Multiple dose study of interactions between artesunate and artemisinin in healthy volunteers

British Journal of Clinical Pharmacology

Volumn 52, Issue 4, 2001, Pages 377-385

  Zhang, Shu Qiu ^a   Hai, Trinh Ngoc ^b   Ilett, Kenneth F ^c   Huong, Dinh Xuan ^b   Davis, Timothy M E ^c   Ashton, Michael ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b National Institute of Malariology Parasitology and Entomology Hanoi   (Viet Nam)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Artemisinin; Artesunate; Dihydroartemisinin; Induction; Inhibition; Pharmacokinetics

Indexed keywords

ARTEMISININ; ARTESUNATE; DIHYDROARTEMISININ; MW 284; MW 384; PRODRUG;

ARTICLE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG ELIMINATION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RACE; ULTRAVIOLET RADIATION; VIET NAM; VOLUNTEER;

ADMINISTRATION, ORAL; ADULT; ANTIMALARIALS; AREA UNDER CURVE; ARTEMISININS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG ADMINISTRATION SCHEDULE; DRUG INTERACTIONS; HALF-LIFE; HUMANS; LINEAR MODELS; MALE; METABOLIC CLEARANCE RATE; SESQUITERPENES;

EID: 0034795604     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0306-5251.2001.01461.x     Document Type: Article

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