Mechanism of measles virus failure to activate NF-κB in neuronal cells

Journal of NeuroVirology

Volumn 7, Issue 1, 2001, Pages 25-34

  Fang, Yu Yan ^a,b   Song, Zan Min ^a,b   Dhib Jalbut, Suhayl ^a,b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b DEPARTMENT OF VETERANS AFFAIRS   (United States)

Author keywords

I B ; Measles virus; Neuronal cells; NF B

Indexed keywords

BETA INTERFERON; CYCLOHEXIMIDE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOPROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MEMBRANE COFACTOR PROTEIN; VIRUS RECEPTOR;

ANTIGEN EXPRESSION; ANTIVIRAL ACTIVITY; ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; EXPOSURE; EXPRESSION VECTOR; GENE EXPRESSION; GENE INDUCTION; GENETIC TRANSFECTION; GLIA CELL; HOST RESISTANCE; HUMAN; HUMAN CELL; MEASLES; MEASLES VIRUS; MOLECULAR RECOGNITION; NERVE CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION;

ANTIGENS, CD; ANTIGENS, CD46; CELL LINE; DNA-BINDING PROTEINS; HUMANS; I-KAPPA B PROTEINS; MEASLES VIRUS; MEMBRANE GLYCOPROTEINS; NEUROGLIA; NEURONS; NF-KAPPA B; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN ISOFORMS; PROTEIN SYNTHESIS INHIBITORS; SIGNAL TRANSDUCTION; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034794396     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.1080/135502801300069610     Document Type: Article

References (53)

1. Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme
2. Constitutive phosphorylation of IκBα by casein kinase II
3. Coupling of a signal response domain in IκBα to multiple pathways for NFκB activation
4. Control of IκBα proteolysis by site-specific, signal-induced phosphorylation
5. Mapping of the primary binding site of measles virus to its receptor CD46
6. Placenta growth factor: Identification and characterization of a novel isoform generated by RNA alternative splicing
7. The double-stranded RNA-dependent protein kinase PKR: Structure and function
8. Adult human glial cells can present target antigens to HLA-restricted cytotoxic T-cells
9. Direct evidence that interferon-β mediates enhanced HLA-class I expression in measles virus-infected cells
10. Measles virus diseases
11. Differential up-regulation of HLA class I molecules on neuronal and glial cell lines by virus infection correlates with differential induction of IFN-β
12. Failure of measles virus to activate nuclear factor-κB in neuronal cells: Implications on the immune response to viral infections in the central nervous system
13. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
14. The human CD46 molecule is a receptor for measles virus (Edmonston strain)
15. Mechanistic aspects of NFκB regulation: The emerging role of phosphorylation and proteolysis
16. Major histocompatibility complex class I expression on neurons in subacute sclerosing panencephalitis and experimental subacute measles encephalitis
17. The immune response in viral encephalitis
18. Characterization of an immediate-early gene induced in adherent monocytes that encode IκB-like activity
19. Viral persistence in neurons explained by lack of major histocompatibility class I expression
20. Augmentation of major histocompatibility complex class I and ICAM-1 expression on glial cells following measles virus infection: Evidence for the role of type-1 interferon
21. Double-stranded RNA-dependent protein kinase activates transcription factor NF-κB by phosphorylating IκB
22. Induction of MHC class I antigens on glial cells is dependent on persistent mouse hepatitis virus infection
23. Raf-1 protein kinase activates the NF-κB transcription factor by dissociating the cytoplasmic NF-κB-IκB complex
24. Membrane cofactor protein (MCP or CD46): Newest member of the regulators of complement activation gene cluster
25. Membrane cofactor protein
26. Flavivirus infection up-regulates the expression of class I and class II major histocompatibility antigens on and enhances T cell recognition of astrocytes in vitro
27. Phosphorylation of canine distemper virus P protein by protein kinase C-ζ and casein kinase II
28. MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1
29. Positive and negative control of human interferon-β gene expression
30. Catalysis by a multiprotein IκB kinase complex
31. Immune mechanisms relating to viral infections of the nervous system
32. IKK-1 and IKK-2: Cytokine-activated IκB kinases essential for NF-κB activation
33. Differential regulation of IκB kinase α and β by two upstream kinases, NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1
34. Human membrane cofactor protein (CD46) acts as a cellular receptor for measles virus
35. Measles virus haemagglutinin induces down-regulation of gp57/67, a molecule involved in virus binding
36. LD78β, a non-allelic variant of human MIP-1 α (LD78α), has enhanced receptor interactions and potent HIV suppressive activity
37. Major Egr3 isoforms are generated via alternate translation start sites and differ in their abilities to activate transcription
38. Absence of measles virus receptor (CD46) in lesions of subacute sclerosing panencephalitis brains
39. An isoform of Nurr1 functions as a negative inhibitor of the NGFI-B family signaling
40. Viral persistence
41. NF-κB activation by tumour necrosis factor requires the Akt serine-threonine kinase
42. Membrane cofactor protein of the complement system: Alternative splicing of serine/threonine/proline-rich exons and cytoplasmic tails produces multiple isoforms that correlate with protein phenotype
43. A calcium-dependent antibody for identification and purification of recombinant proteins
44. IKK-γ is an essential regulatory subunit of the IκB kinase complex
45. Purification and characterization of a membrane protein (gp45-70) that is a cofactor for cleavage of C3b and C4b
46. Quantitative analysis of membrane cofactor protein (MCP) of complement. High expression of MCP on human leukemia cell lines, which is down-regulated during cell differentiation
47. In vitro activation and nuclear translocation of NF-κB catalyzed by cyclic AMP-dependent protein kinase and protein kinase C
48. Coronavirus infection induces H-2 antigen expression on oligodendrocytes and astrocytes
49. Inducible cAMP early repressor ICER down-regulation of CREB gene expression in Sertoli cells
50. Neuron-specific regulation of major histocompatibility complex class I, interferon-β, and anti-viral state genes
51. Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase
52. A big gene linked to small eyes encodes multiple Mitf isoforms: Many promoters make light work
53. CREB as a memory modulator: Induced expression of a dCREB2 activator isoform enhances long-term memory in Drosophila