메뉴 건너뛰기




Volumn 70, Issue 4, 1996, Pages 989-997

Cell surface expression of the human N-methyl-D-aspartate receptor subunit 1a requires the co-expression of the NR2A subunit in transfected cells

Author keywords

antibody; biotinylation; ion channels; NMDA receptors; plasma membrane; transfection

Indexed keywords

CELL SURFACE RECEPTOR; COMPLEMENTARY DNA; DEXAMETHASONE; ION CHANNEL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RECEPTOR SUBUNIT;

EID: 0030065055     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(95)00419-X     Document Type: Article
Times cited : (90)

References (46)
  • 1
    • 0027185380 scopus 로고
    • Homomeric and native α7 acetylcholine receptors exhibit remarkably similar but non-identical pharmacological properties, suggesting that the native receptor is a heteromeric protein complex
    • Anand R., Peng X. and Lindstrom J. (1995) Homomeric and native α7 acetylcholine receptors exhibit remarkably similar but non-identical pharmacological properties, suggesting that the native receptor is a heteromeric protein complex. Fedn Eur. biochem. Socs Lett. 327, 241-246.
    • (1995) Fedn Eur. Biochem. Socs Lett. , vol.327 , pp. 241-246
    • Anand, R.1    Peng, X.2    Lindstrom, J.3
  • 3
    • 0028934398 scopus 로고
    • Transfection of N-methyl-D-aspartate receptors in a nonneuronal cell line leads to cell death
    • Anegawa N. J., Lynch D. R., Verdoorn T. A. and Pritchett D. B. (1995) Transfection of N-methyl-D-aspartate receptors in a nonneuronal cell line leads to cell death. J. Neurochem. 64, 2004-2012.
    • (1995) J. Neurochem. , vol.64 , pp. 2004-2012
    • Anegawa, N.J.1    Lynch, D.R.2    Verdoorn, T.A.3    Pritchett, D.B.4
  • 4
    • 0028263401 scopus 로고
    • Stable transfection of the NMDAR1 subunit in Chinese hamster ovary cells fails to produce a functional N-methyl-D-aspartate receptor
    • Boeckman F. A. and Aizenman E. (1994) Stable transfection of the NMDAR1 subunit in Chinese hamster ovary cells fails to produce a functional N-methyl-D-aspartate receptor. Neurosci. Lett. 173, 189-192.
    • (1994) Neurosci. Lett. , vol.173 , pp. 189-192
    • Boeckman, F.A.1    Aizenman, E.2
  • 5
    • 0027490681 scopus 로고
    • Protein chemical characterization and immunocytochemical localization of the NMDA receptor subunit NMDA R1
    • Brose N., Gasic G. P., Vetter D. E., Sullivan J. M. and Heinemann S. F. (1993) Protein chemical characterization and immunocytochemical localization of the NMDA receptor subunit NMDA R1. J. biol. Chem. 268, 22,663-22,671.
    • (1993) J. Biol. Chem. , vol.268 , pp. 22663-22671
    • Brose, N.1    Gasic, G.P.2    Vetter, D.E.3    Sullivan, J.M.4    Heinemann, S.F.5
  • 6
    • 0026640405 scopus 로고
    • Immunological detection of the NMDAR1 glutamate receptor subunit expressed in human embryonic kidney 293 cells and in rat brain
    • Chazot P. L., Cik M. and Stephenson F. A. (1992) Immunological detection of the NMDAR1 glutamate receptor subunit expressed in human embryonic kidney 293 cells and in rat brain. J. Neurochem. 59, 1176-1178.
    • (1992) J. Neurochem. , vol.59 , pp. 1176-1178
    • Chazot, P.L.1    Cik, M.2    Stephenson, F.A.3
  • 7
    • 0027938709 scopus 로고
    • Molecular characterization of N-methyl-D-aspartate receptors expressed in mammalian cells yields evidence for the coexistence of three subunit types within a discrete receptor molecule
    • Chazot P. L., Coleman S. K., Cik M. and Stephenson A. (1994) Molecular characterization of N-methyl-D-aspartate receptors expressed in mammalian cells yields evidence for the coexistence of three subunit types within a discrete receptor molecule. J. biol. Chem. 269, 24,403-24,409.
    • (1994) J. Biol. Chem. , vol.269 , pp. 24403-24409
    • Chazot, P.L.1    Coleman, S.K.2    Cik, M.3    Stephenson, A.4
  • 8
    • 0027746221 scopus 로고
    • Optimal expression of cloned NMDAR1/NMDAR2A heteromeric glutamate receptors: A biochemical characterization
    • Cik M., Chazot P. L. and Stephenson F. A. (1993) Optimal expression of cloned NMDAR1/NMDAR2A heteromeric glutamate receptors: a biochemical characterization. Biochem. J. 296, 877-883.
    • (1993) Biochem. J. , vol.296 , pp. 877-883
    • Cik, M.1    Chazot, P.L.2    Stephenson, F.A.3
  • 9
    • 0024390434 scopus 로고
    • Fibroblasts transfected with Torpedo acetylcholine receptor βγ, and δ subunit cDNAs express functional receptors when transfected with a retroviral α recombinant
    • Claudio T., Paulson H. L., Green W. N., Ross A. F., Hartmann D. S. and Hayden D, (1989) Fibroblasts transfected with Torpedo acetylcholine receptor βγ, and δ subunit cDNAs express functional receptors when transfected with a retroviral α recombinant. J. Cell Biol. 108, 2277-2290.
    • (1989) J. Cell Biol. , vol.108 , pp. 2277-2290
    • Claudio, T.1    Paulson, H.L.2    Green, W.N.3    Ross, A.F.4    Hartmann, D.S.5    Hayden, D.6
  • 10
    • 0023084134 scopus 로고
    • Use of eukaryotic expression technology in the functional analysis of cloned genes
    • Cullen B. R. (1987) Use of eukaryotic expression technology in the functional analysis of cloned genes. Meth. Enzym. 152, 684-704.
    • (1987) Meth. Enzym. , vol.152 , pp. 684-704
    • Cullen, B.R.1
  • 12
    • 0026686821 scopus 로고
    • Cloning of an apparent splice variant of rat N-methyl-D-aspartate receptor NMDAR1 with altered sensitivity to polyamines and activators of protein kincase C
    • Durand G. M., Gregor P., Zheng X., Bennett M. V. L., Uhl G. R. and Zukin R. S. (1992) Cloning of an apparent splice variant of rat N-methyl-D-aspartate receptor NMDAR1 with altered sensitivity to polyamines and activators of protein kincase C. Proc. natn. Acad. Sci. U.S.A. 89, 9359-9363.
    • (1992) Proc. Natn. Acad. Sci. U.S.A. , vol.89 , pp. 9359-9363
    • Durand, G.M.1    Gregor, P.2    Zheng, X.3    Bennett, M.V.L.4    Uhl, G.R.5    Zukin, R.S.6
  • 13
    • 0028998419 scopus 로고
    • Ion-channel assembly
    • Green W. and Millar N. (1995) Ion-channel assembly. Trends Neurosci. 18, 280-287.
    • (1995) Trends Neurosci. , vol.18 , pp. 280-287
    • Green, W.1    Millar, N.2
  • 14
    • 0028795941 scopus 로고
    • Recombinant human NMDA homomeric NMDAR1 receptors expressed in mammalian cells form a high-affinity glycine antagonist binding site
    • Grimwood S., Le Bourdellès B. and Whiting P. J. (1995) Recombinant human NMDA homomeric NMDAR1 receptors expressed in mammalian cells form a high-affinity glycine antagonist binding site. J. Neurochem. 64, 525-530.
    • (1995) J. Neurochem. , vol.64 , pp. 525-530
    • Grimwood, S.1    Le Bourdellès, B.2    Whiting, P.J.3
  • 16
    • 0025902142 scopus 로고
    • Assembly of the mammalian muscle acetylcholine receptor in transfected Cos cells
    • Gu Y., Forsayeth J. R., Verrall S., Yu X. M. and Hall Z. W. (1991) Assembly of the mammalian muscle acetylcholine receptor in transfected Cos cells. J. Cell Biol. 114, 799-807.
    • (1991) J. Cell Biol. , vol.114 , pp. 799-807
    • Gu, Y.1    Forsayeth, J.R.2    Verrall, S.3    Yu, X.M.4    Hall, Z.W.5
  • 17
    • 0024367836 scopus 로고
    • Cloning by functional expression of a member of the glutamate receptor family
    • Hollmann M., O'Shea-Greenfield A., Rogers S. W. and Heinemann S. (1989) Cloning by functional expression of a member of the glutamate receptor family. Nature 342, 643-648.
    • (1989) Nature , vol.342 , pp. 643-648
    • Hollmann, M.1    O'Shea-Greenfield, A.2    Rogers, S.W.3    Heinemann, S.4
  • 18
    • 0028596211 scopus 로고
    • N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1
    • Hollmann M., Maron C. and Heinemann S. (1994) N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1. Neuron 13, 1331-1343.
    • (1994) Neuron , vol.13 , pp. 1331-1343
    • Hollmann, M.1    Maron, C.2    Heinemann, S.3
  • 21
    • 0027478586 scopus 로고
    • Molecular cloning and chromosomal localization of the key subunit of the human N-methyl-D-aspartate receptor
    • Karp S. J., Masu M., Eki T., Ozawa K. and Nakanishi S. (1993) Molecular cloning and chromosomal localization of the key subunit of the human N-methyl-D-aspartate receptor. J. biol. Chem. 268, 3728-3733.
    • (1993) J. Biol. Chem. , vol.268 , pp. 3728-3733
    • Karp, S.J.1    Masu, M.2    Eki, T.3    Ozawa, K.4    Nakanishi, S.5
  • 23
    • 0027360286 scopus 로고
    • Characterization of the NMDAR1, NMDAR2a and NMDAR2c receptor proteins
    • Köpke A. K., Bonk I., Sydow S., Menke H. and Spiess J. (1993) Characterization of the NMDAR1, NMDAR2a and NMDAR2c receptor proteins. Protein Sci. 2, 2066-2076.
    • (1993) Protein Sci. , vol.2 , pp. 2066-2076
    • Köpke, A.K.1    Bonk, I.2    Sydow, S.3    Menke, H.4    Spiess, J.5
  • 24
    • 0027716526 scopus 로고
    • Assembly of the inhibitory glycine receptor: Identification of amino acid sequence motifs governing subunit stoichiometry
    • Kuhse J., Laube B., Magalei D. and Betz H. (1993) Assembly of the inhibitory glycine receptor: identification of amino acid sequence motifs governing subunit stoichiometry. Neuron 11, 1049-1056.
    • (1993) Neuron , vol.11 , pp. 1049-1056
    • Kuhse, J.1    Laube, B.2    Magalei, D.3    Betz, H.4
  • 26
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 277, 680-685.
    • (1970) Nature , vol.277 , pp. 680-685
    • Laemmli, U.K.1
  • 27
    • 0028206275 scopus 로고
    • Cloning, functional co-expression and pharmacological characterization of human cDNAs encoding NMDA receptor NMDAR1 and NMDAR2A subunits
    • Le Bourdellès B., Wafford K. A., Kemp J. A., Marshall G., Bain C., Wilcox A. S., Sikela J. M. and Whiting P. J. (1994) Cloning, functional co-expression and pharmacological characterization of human cDNAs encoding NMDA receptor NMDAR1 and NMDAR2A subunits. J. Neurochem. 62, 2091-2098.
    • (1994) J. Neurochem. , vol.62 , pp. 2091-2098
    • Le Bourdellès, B.1    Wafford, K.A.2    Kemp, J.A.3    Marshall, G.4    Bain, C.5    Wilcox, A.S.6    Sikela, J.M.7    Whiting, P.J.8
  • 30
    • 0020616951 scopus 로고
    • Assembly in vivo of mouse acetylcholine receptor: Identification of an α subunit species that may be an assembly intermediate
    • Merlie J. P. and Lindstrom J. (1983) Assembly in vivo of mouse acetylcholine receptor: identification of an α subunit species that may be an assembly intermediate. Cell 34, 747-757.
    • (1983) Cell , vol.34 , pp. 747-757
    • Merlie, J.P.1    Lindstrom, J.2
  • 31
    • 0027538458 scopus 로고
    • Biochemical and immunocytochemical characterization of antipeptide antibodies to a cloned GluR1 glutamate receptor subunit: Cellular and subcellular distribution in the rat forebrain
    • Molnár E., Baude A., Richmond S. A., Patel P. B., Somogyi P. and McIlhinney R. A. J. (1993) Biochemical and immunocytochemical characterization of antipeptide antibodies to a cloned GluR1 glutamate receptor subunit: cellular and subcellular distribution in the rat forebrain. Neuroscience 53, 307-326.
    • (1993) Neuroscience , vol.53 , pp. 307-326
    • Molnár, E.1    Baude, A.2    Richmond, S.A.3    Patel, P.B.4    Somogyi, P.5    McIlhinney, R.A.J.6
  • 32
    • 0028343648 scopus 로고
    • Developmental and regional expression in the rat brain and functional properties of four NMDA receptors
    • Monyer H., Burnashev N., Laurie D. L., Sakmann B. and Seeburg P. H. (1994) Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 12, 529-540.
    • (1994) Neuron , vol.12 , pp. 529-540
    • Monyer, H.1    Burnashev, N.2    Laurie, D.L.3    Sakmann, B.4    Seeburg, P.H.5
  • 35
    • 0025221685 scopus 로고
    • A family of glutamate receptor genes: Evidence for the formation of heteromultimeric receptors with distinct channel properties
    • Nakanishi N., Schneider N. A. and Axel R. (1990) A family of glutamate receptor genes: evidence for the formation of heteromultimeric receptors with distinct channel properties. Neuron 5, 569-581.
    • (1990) Neuron , vol.5 , pp. 569-581
    • Nakanishi, N.1    Schneider, N.A.2    Axel, R.3
  • 36
    • 0028087773 scopus 로고
    • The NMDA receptor subunits NMDAR2A and NMDAR2B show histological and ultrastructural localization patterns similar to those of NMDAR1
    • Petralia R. S., Wang Y.-X. and Wenthold R. J. (1994) The NMDA receptor subunits NMDAR2A and NMDAR2B show histological and ultrastructural localization patterns similar to those of NMDAR1. J. Neurosci. 14, 6102-6120.
    • (1994) J. Neurosci. , vol.14 , pp. 6102-6120
    • Petralia, R.S.1    Wang, Y.-X.2    Wenthold, R.J.3
  • 37
    • 0028157362 scopus 로고
    • Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody
    • Petralia R. S., Yokotani N. and Wenthold R. J. (1994) Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody. J. Neurosci. 14, 667-696.
    • (1994) J. Neurosci. , vol.14 , pp. 667-696
    • Petralia, R.S.1    Yokotani, N.2    Wenthold, R.J.3
  • 38
    • 0027200341 scopus 로고
    • Molecular cloning, functional expression and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain
    • Planells-Cases R., Sun W., Ferrer-Montiel A. V. and Montai M. (1993) Molecular cloning, functional expression and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain. Proc. natn. Acad. Sci. U.S.A. 90, 5057-5061.
    • (1993) Proc. Natn. Acad. Sci. U.S.A. , vol.90 , pp. 5057-5061
    • Planells-Cases, R.1    Sun, W.2    Ferrer-Montiel, A.V.3    Montal, M.4
  • 39
    • 85031230378 scopus 로고    scopus 로고
    • Pharmacological properties of recombinant human N-methyl-D-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse fibroblast cells
    • in press
    • Priestley T., Laughton P., Myers J., Le Bourdellès B., Kerby J. and Whiting P. J. Pharmacological properties of recombinant human N-methyl-D-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse fibroblast cells. Molec. Pharmacol. (in press).
    • Molec. Pharmacol.
    • Priestley, T.1    Laughton, P.2    Myers, J.3    Le Bourdellès, B.4    Kerby, J.5    Whiting, P.J.6
  • 40
    • 0026098974 scopus 로고
    • Assembly of Torpedo acetylcholine receptors in Xenopus oocytes
    • Saedi M. S., Conroy W. G. and Lindstrom J. (1991) Assembly of Torpedo acetylcholine receptors in Xenopus oocytes. J. Cell Biol. 112, 1007-1015.
    • (1991) J. Cell Biol. , vol.112 , pp. 1007-1015
    • Saedi, M.S.1    Conroy, W.G.2    Lindstrom, J.3
  • 41
    • 0028219211 scopus 로고
    • Changing subunit composition of heteromeric NMDA receptors during development of rat cortex
    • Sheng M., Cummings J., Roldan L. A., Jan Y. N. and Jan L. Y. (1994) Changing subunit composition of heteromeric NMDA receptors during development of rat cortex. Nature 368, 144-147.
    • (1994) Nature , vol.368 , pp. 144-147
    • Sheng, M.1    Cummings, J.2    Roldan, L.A.3    Jan, Y.N.4    Jan, L.Y.5
  • 42
    • 0028019479 scopus 로고
    • Rapid turnover rate of the hippocampal synaptic NMDA-R1 receptor subunits
    • Soltesz I., Zhou Z., Smith G. M. and Mody I. (1994) Rapid turnover rate of the hippocampal synaptic NMDA-R1 receptor subunits. Neurosci. Lett. 181, 5-8.
    • (1994) Neurosci. Lett. , vol.181 , pp. 5-8
    • Soltesz, I.1    Zhou, Z.2    Smith, G.M.3    Mody, I.4
  • 43
    • 0026766877 scopus 로고
    • Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing
    • Sugihara H., Moriyoshi K., Ishii T., Masu M. and Nakanishi S. (1992) Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing. Biochem. biophys. Res. Commun. 185, 826-832.
    • (1992) Biochem. Biophys. Res. Commun. , vol.185 , pp. 826-832
    • Sugihara, H.1    Moriyoshi, K.2    Ishii, T.3    Masu, M.4    Nakanishi, S.5
  • 44
    • 0027207494 scopus 로고
    • Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurons from excitotoxicity and reduce focal ischaemic infarctions
    • Wahlestedt C., Golanov E., Yamamoto S., Yee F., Ericson H., Yoo H., Inturrisi C. E. and Reis D. J. (1993) Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurons from excitotoxicity and reduce focal ischaemic infarctions. Nature 363, 260-263.
    • (1993) Nature , vol.363 , pp. 260-263
    • Wahlestedt, C.1    Golanov, E.2    Yamamoto, S.3    Yee, F.4    Ericson, H.5    Yoo, H.6    Inturrisi, C.E.7    Reis, D.J.8
  • 46
    • 0028873973 scopus 로고
    • Expression of mRNAs encoding subunits of the NMDA receptor in developing rat brain
    • Zhong J., Carrozza D. P., Williams K., Pritchett D. B. and Molinoff P. B. (1995) Expression of mRNAs encoding subunits of the NMDA receptor in developing rat brain. J. Neurochem. 64, 531-539.
    • (1995) J. Neurochem. , vol.64 , pp. 531-539
    • Zhong, J.1    Carrozza, D.P.2    Williams, K.3    Pritchett, D.B.4    Molinoff, P.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.