Inhibition of attaching and effacing lesion formation following enteropathogenic Escherichia coli and Shiga toxin-producing E. coli infection

Infection and Immunity

Volumn 69, Issue 11, 2001, Pages 7152-7158

  Johnson Henry, K ^a   Wallace, J L ^a   Basappa, N S ^a   Soni, R ^a   Wu, G K P ^a   Sherman, P M ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ALPHA ACTININ; ARACHIDONATE 5 LIPOXYGENASE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NORDIHYDROGUAIARETIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PHOSPHOLIPASE C INHIBITOR; SHIGA TOXIN; WORTMANNIN;

ARTICLE; BACTERIAL COLONIZATION; BACTERIUM ADHERENCE; CELL ULTRASTRUCTURE; CYTOSKELETON; ENTEROBACTER INFECTION; EPITHELIUM CELL; ESCHERICHIA COLI; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTININ; ANDROSTADIENES; ARACHIDONATE 5-LIPOXYGENASE; BACTERIAL ADHESION; CELL LINE; CHROMONES; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; ESCHERICHIA COLI; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; MORPHOLINES; NITROBENZENES; NORDIHYDROGUAIARETIC ACID; PHOSPHOLIPASE C; PHOSPHOLIPID ETHERS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; SHIGA TOXIN; SIGNAL TRANSDUCTION; SULFONAMIDES;

EID: 0034773509     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.11.7152-7158.2001     Document Type: Article

References (36)

1. Protein phosphorylation by protein kinase C in HEp-2 cells infected with enteropathogenic Escherichia coli
2. Do eicosanoids cause colonic dysfunction in experimental E. coli O157:H7 (EHEC) infection?
3. Pathogenesis and evolution of virulence in enteropathogenic and enterohemorrhagic Escherichia coli
4. The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton
5. A diarrheal pathogen, enteropathogenic Escherichia coli (EPEC), triggers a flux of inositol phosphates in infected epithelial cells
6. Phosphoinositide kinases
7. NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro
8. Recruitment of cytoskeletal and signaling proteins to enteropathogenic and enterohemorrhagic Escherichia coli pedestals
9. Enteropathogenic E. coli translocated intimin receptor, Tir, interacts directly with alpha-actinin
10. Role of intimin and bundle-forming pili in enteropathogenic Escherichia coli adhesion to pediatric intestinal tissue in vitro
11. Signal transduction responses following adhesion of verocytotoxin-producing Escherichia coli
12. α-actinin accumulation in epithelial cells infected with attaching and effacing gastrointestinal pathogens
13. Cyclooxygenase selectivity and the risk of gastro-intestinal complications of various non-steroidal anti-inflammatory drugs: A clinical consideration
14. Actin accumulation at sites of bacterial adhesion to tissue culture cells: Basis of a new diagnostic test for enteropathogenic and enterohemorrhagic Escherichia coli
15. A third secreted protein that is encoded by the enteropathogenic Escherichia coli pathogenicity island is required for transduction of signals and for attaching and effacing activities in host cells
16. Cytoskeleton reorganization by G protein-coupled receptors is dependent on phosphoinositide 3-kinase γ, a Rac guanosine exchange factor, and Rac
17. Phosphoinositide lipids as signaling molecules: Common themes for signal transduction, cytoskeletal regulation, and membrane trafficking
18. Translocated EspF protein from enteropathogenic Escherichia coli disrupts host intestinal barrier function
19. The Yersinia Yops inhibit invasion of Listeria, Shigella, and Edwardsiella but not Salmonella into epithelial cells
20. Signal transduction and invasion of epithelial cells by S. typhimurium
21. Rac mediates growth factor-induced arachidonic acid release
22. Epidermal growth factor-induced actin remodeling is regulated by 5-lipoxygenase and cyclooxygenase products
23. Cholera toxin B subunit activates arachidonic acid metabolism
24. Signal transduction pathways involved in enterohemorrhagic Escherichia coli-induced alterations in T84 epithelial permeability
25. Infection of T84 cells with enteropathogenic Escherichia coli alters barrier and transport functions
26. Selective inhibition of phosphatidylinositol phospholipase C by cytotoxic ether lipid analogues
27. Eicosanoids and their role in the pathogenesis of diarrhoeal diseases
28. Enteropathogenic and enterohaemorrhagic Escherichia coli and diarrhoea
29. Expression of attaching/effacing activity by enteropathogenic Escherichia coli depends on growth phase, temperature, and protein synthesis upon contact with epithelial cells
30. Activation of NF-kappa B in intestinal epithelial cells by enteropathogenic Escherichia coli
31. Signaling to the actin cytoskeleton
32. + secretion in human distal colon driven by prostaglandin E2
33. Molecular physiology and pathophysiology of tight junctions. V. Assault of the tight junction by enteric pathogens
34. The molecular biology of mammalian arachidonic acid metabolism
35. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
36. Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction