Pathogenesis and evolution of virulence in enteropathogenic and enterohemorrhagic Escherichia coli

Journal of Clinical Investigation

Volumn 107, Issue 5, 2001, Pages 539-548

  Donnenberg, Michael S ^a   Whittam, Thomas S ^b  

^a UNIVERSITY OF MARYLAND   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI ENDOTOXIN; VIRULENCE FACTOR;

BACTERIAL VIRULENCE; CLINICAL FEATURE; CYTOSKELETON; ESCHERICHIA COLI; EVOLUTION; GENETIC POLYMORPHISM; HOST PARASITE INTERACTION; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PHENOTYPE; PLASMID; PRIORITY JOURNAL; REVIEW;

EID: 0035095613     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI12404     Document Type: Review

References (46)

1. Genetic variation and evolutionary processes in natural populations of Escherichia coli
2. Evolutionary relationships among pathogenic and nonpathogenic Escherichia coli strains inferred from multilocus enzyme electrophoresis and mdh sequence studies
3. The complete genome sequence of Escherichia coli K-12
4. Molecular archaeology of the Escherichia coli genome
5. Genome sequence of enterohaemorrhagic Escherichia coli O157:H7
6. Recombination and population structure in Escherichia coli
7. Parallel evolution of virulence in pathogenic Escherichia coli
8. Clonal relationship among invasive and non-invasive strains of enteroinvasive Escherichia coli serogroups
9. The link between phylogeny and virulence in Escherichia coli extraintestinal infection
10. Phylogenetic analysis of Escherichia coli strains causing neonatal meningitis suggests horizontal gene transfer from a predominant pool of highly virulent B2 group strains
11. Diarrheagenic Escherichia coli
12. Virulence determinants of uropathogenic Escherichia coli
13. Interactions between enteropathogenic Escherichia coli and epithelial cells
14. Effects of bfp mutations on biogenesis of functional enteopathogenic Escherichia coli type IV pili
15. The role of BfpF a member of the PilT family of putative nucleotide-binding proteins in type IV pilus biogenesis and in interactions between enteropathogenic Escherichia coli and host cells
16. The type IV bundle-forming pilus of enteropathogenic Escherichia coli undergoes dramatic alterations in structure associated with bacterial adherence, aggregation and dispersal
17. Type IV pili, transient bacterial aggregates, and virulence of enteropathogenic Escherichia coli
18. Enteropathogenic and enterohaemorrhagic Escherichia coli: More subversive elements
19. Type III secretion systems: Machines to deliver bacterial proteins into eukaryotic cells?
20. Enteropathogenic Escherichia coli: Cellular harassment
21. Phosphorylation of tyrosine 474 of the enteropathogenic Escherichia coli (EPEC) Tir receptor molecule is essential for actin nucleating activity and is preceded by additional host modifications
22. Crystal structure of enteropathogenic Escherichia coli intimin-receptor complex
23. Insertion of EspD into epithelial target cell membranes by infecting enteropathogenic Escherichia coli
24. Expression of the EspB protein of enteropathogenic Escherichia coli within HeLa cells affects stress fibers and cellular morphology
25. Enteropathogenic E. coli acts through WASP and Arp2/3 complex to form actin pedestals
26. A novel proline-rich protein, EspF, is secreted from enteropathogenic Escherichia coli via the type III export pathway
27. Translocated EspF protein from enteropathogenic Escherichia coli disrupts host intestinal barrier function
28. Role of EspF in host cell death induced by enteropathogenic Escherichia coli
29. A large toxin from pathogenic Escherichia coli strains that inhibits lymphocyte activation
30. Clonal analysis of EPEC serogroups
31. Escherichia coli serogroup O111 includes several clones of diarrheagenic strains with different virulence properties
32. Complete DNA sequence and structural analysis of the enteropathogenic Escherichia coli adherence factor plasmid
33. Molecular variation among type IV pilin (bfpA) genes from diverse enteropathogenic Escherichia coli strains
34. Current concepts: Escherichia coli O157:H7 and the hemolytic-uremic syndrome
35. Escherichia coli O157:H7: Clinical, diagnostic, and epidemiological aspects of human infection
36. The epidemiology of infections caused by Escherichia coli O157:H7, other enterohemorrhagic E. coli, and the associated hemolytic uremic syndrome
37. The complete DNA sequence and analysis of the large virulence plasmid of Escherichia coli O157:H7
38. Complete nucleotide sequences of 93-kb and 3.3-kb plasmids of an enterohemorrhagic Escherichia coli O157:H7 derived from Sakai outbreak
39. Primary cultures of human endothelial cells are susceptible to low doses of Shiga toxins and undergo apoptosis
40. The cloned locus of enterocyte effacement from enterohemorrhagic Escherichia coli O157:H7 is unable to confer the attaching and effacing phenotype upon E-coli K-12
41. Virulence properties of atypical EPEC strains
42. Genotypic and phenotypic changes in the emergence of Escherichia coli O157:H7
43. Molecular evolution and mosaic structure of α, β, and γ intimins of pathogenic Escherichia coli
44. Isogenic lysogens of diverse shiga toxin 2-encoding bacteriophages produce markedly different amounts of Shiga toxin
45. A genomic island, termed high-pathogenicity island, is present in certain non-O157 Shiga toxin-producing Escherichia coli clonal lineages
46. Molecular characteristics and epidemiological significance of Shiga toxin-producing Escherichia coli O26 strains