Ciliary neurotrophic factor, a gp130 cytokine, regulates preovulatory surges of luteinizing hormone and prolactin in the rat

Neuroendocrinology

Volumn 74, Issue 5, 2001, Pages 281-287

  Watanobe, Hajime ^a   Habu, Satoshi ^b  

^a INTERNATIONAL UNIVERSITY OF HEALTH AND WELFARE   (Japan)

^b AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Ciliary neurotrophic factor; Fasting; Gonadal steroids; Gonadotropins; Interleukins; Ovulation; Prolactin

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; LUTEINIZING HORMONE; PROLACTIN; STEROID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; COMPARATIVE STUDY; CONTROLLED STUDY; DIET RESTRICTION; DILUTION; DOSE RESPONSE; FEEDING; FEMALE; HORMONAL REGULATION; HORMONE ACTION; MEASUREMENT; NONHUMAN; OVARIECTOMY; OVULATION; PRIORITY JOURNAL; RAT; REPRODUCTION;

ANIMALS; BRAIN; CILIARY NEUROTROPHIC FACTOR; FEMALE; FOLLICULAR PHASE; HUMANS; IMMUNE SERA; INJECTIONS, INTRAVENTRICULAR; LUTEINIZING HORMONE; OVARY; PROLACTIN; RATS; RATS, WISTAR; RECOMBINANT PROTEINS;

EID: 0034766496     PISSN: 00283835     EISSN: None     Source Type: Journal    
DOI: 10.1159/000054695     Document Type: Article

References (36)

1. Ciliary neurotrophic factor: A review
2. The neurotrophins and CNTF: Two families of collaborative neurotrophic factors
3. Interleukin-6-type cytokine signaling through the gp130/Jak/STAT pathway
4. Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor
5. The expression of CNTF message and immunoreactivity in the central and peripheral nervous system of the rat
6. Localization of CNTF immunoreactivity to neurons and astroglia in the CNS
7. Injury-induced regulation of ciliary neurotrophic factor mRNA in the adult rat brain
8. Cerebrospinal-fluid ciliary neurotrophic factor in neurological patients
9. Increase of ciliary neurotrophic factor (CNTF) in the ischemic rat brain as determined by a sensitive enzyme-linked immunoassay
10. Differential regulation of ciliary neurotrophic factor and its receptor in the rat hippocampus following transient global ischemia
11. Immunohistochemical localization of ciliary neurotrophic factor receptor alpha expression in the rat nervous system
12. Ciliary neurotrophic factor receptor alpha-immunoreactivity in the monkey central nervous system
13. Ciliary neurotrophic factor corrects obesity and diabetes associated with leptin deficiency and resistance
14. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
15. Secretory, endocrine, and autocrine/paracrine function of the adipocyte
16. Leptin regulation of neuroendocrine systems
17. The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors
18. Ciliary neurotrophic factor is catabolic and shares with IL-6 the capacity to induce an acute phase response
19. A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis
20. Leptin and ciliary neurotrophic factor (CNTF) inhibit fasting-induced suppression of luteinizing hormone release in rats: Role of neuropeptide Y
21. The effects of ciliary neurotrophic factor on the hypothalamo-pituitary gonadal axis in vitro in female rats
22. A significant role of leptin in the generation of steroid-induced luteinizing hormone and prolactin surges in female rats
23. The melanocortin 4 receptor mediates leptin stimulation of luteinizing hormone and prolactin surges in steroid-primed ovariectomized rats
24. Evidence that physiological levels of circulating leptin exert a stimulatory effect on luteinizing hormone and prolactin surges in rats
25. Nonradioactive receptor binding assay for ciliary neurotrophic factor
26. Identification of ciliary neurotrophic factor (CNTF) residues essential for leukemia inhibitory factor receptor binding and generation of CNTF receptor antagonists
27. Role of leptin in hypothalamic-pituitary function
28. Stimulation of prolactin secretion by chronic, but not acute, administration of leptin in the rat
29. Unlike leptin, ciliary neurotrophic factor does not reverse the starvation-induced changes of serum corticosterone and hypothalamic neuropeptide levels but induces expression of hypothalamic inhibitors of leptin signaling
30. The gp130 cytokines interleukin-11 and ciliary neurotrophic factor regulate through specific receptors the function and growth of lactosomatotropic and folliculostellate pituitary cell lines
31. Prolactin: Structure, function, and regulation of secretion
32. Effects of gp130 cytokines ciliary neurotrophic factor (CNTF) and interleukin-11 on pituitary cells: CNTF receptors on pituitary adenomas and stimulation of prolactin and GH secretion in normal rat anterior pituitary aggregate cultures
33. Anorexia induced by activators of the signal transducer gp130
34. Cytokines and cachexia
35. A significant participation of leukemia inhibitory factor in regulating the reproductive function in rats: A novel action of the pleiotropic cytokine