The effects of ciliary neurotrophic factor on the hypothalamo-pituitary gonadal axis in vitro in female rats

Journal of Neuroendocrinology

Volumn 12, Issue 10, 2000, Pages 1009-1013

  Stanley, S A ^a   Todd, J F ^a   Small, C J ^a   Kim, M S ^a   Heath, M M ^a   Anand, P ^a   Ghateind, M A ^a   Bloom, S R ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Ciliary neurotrophic factor; Hypothalamic explants; Luteinizing hormone; Luteinizing hormone releasing hormone; Pituitary

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; CYTOKINE; GONADORELIN; LEPTIN; LEPTIN RECEPTOR; LUTEINIZING HORMONE;

AGED; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BASAL METABOLIC RATE; CELL CULTURE; COMPLEX FORMATION; CONTROLLED STUDY; ESTRUS CYCLE; FEMALE; GONAD FUNCTION; GONADORELIN RELEASE; HYPOPHYSIS CELL; HYPOPHYSIS FUNCTION; HYPOTHALAMUS; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; IN VITRO STUDY; LUTEINIZING HORMONE RELEASE; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; SECOND MESSENGER; SEQUENCE HOMOLOGY;

ANIMALS; CILIARY NEUROTROPHIC FACTOR; FEMALE; GENITALIA, FEMALE; GONADOTROPIN-RELEASING HORMONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; LEPTIN; LUTEINIZING HORMONE; PITUITARY GLAND; RATS; RATS, WISTAR;

EID: 0033833973     PISSN: 09538194     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2826.2000.00550.x     Document Type: Article

References (29)

1. Effects of the obese gene product on body weight regulation in ob/ob mice
2. Leptin is a metabolic signal to the reproductive system
3. Leptin accelerates the onset of puberty in normal female mice
4. Leptin and ciliary neurotropic factor (CNTF) inhibit fasting-induced suppression of luteinizing hormone release in rats: Role of neuropeptide Y
5. Neuropoietic cytokines in the hematopoietic fold
6. Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration
7. Localization of CNTF immuno-reactivity to neurons and astroglia in the CNS
8. Injury-induced regulation of ciliary neurotrophic factor mRNA in the adult rat brain
9. Cerebrospinal-fluid ciliary neurotrophic factor in neurological patients
10. Increase of ciliary neurotrophic factor (CNTF) in the ischemic rat brain as determined by a sensitive enzymelinked immunoassay
11. Ciliary neurotrophic factor and its receptor complex
12. The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors
13. Ciliary neurotrophic factor corrects obesity and diabetes associated with leptin deficiency and resistance
14. Ciliary neurotrophic factor is catabolic and shares with IL-6 the capacity to induce an acute phase response
15. Role of leptin in hypothalamic-pituitary function
16. Galanin is a paracrine inhibitor of gonadotroph function in the female rat
17. Agouti related peptide (Agrp) stimulates the hypothalamo pituitary gonadal axis in vivo and in vitro in male rats
18. Glucagon-like peptide-1 (GLP-1) releases thyrotropin (TSH): Characterization of binding sites for GLP-1 on alpha-TSH cells
19. Recruitment and maturation of small subsets of luteinizing hormone gonadotropes during the estrous cycle
20. Glucagon-like peptide-1 stimulates luteinizing hormone-releasing hormone secretion in a rodent hypothalamic neuronal cell line
21. Influence of endogenous leptin tone on the estrous cycle and luteinizing hormone pulsatility in female rats
22. Leptin receptor immunoreactivity is associated with the Golgi apparatus of hypothalamic neurons and glial cells
23. Expression of a leptin receptor in immortalized gonadotropin-releasing hormone-secreting neurons
24. LHRF, LHRH, LHRH: What controls the secretion of this hormone?
25. Ciliary neurotrophic factor induces type-2 astrocyte differentiation in culture
26. Agonistic and antagonistic variants of ciliary neurotrophic factor (CNTF) reveal functional differences between membrane-bound and soluble CNTF alpha-receptor
27. Expression and androgen regulation of the ciliary neurotrophic factor receptor (CNTFRalpha) in muscles and spinal cord
28. Sexual dimorphism in the spinal cord is absent in mice lacking the ciliary neurotrophic factor receptor