Childhood myeloid leukaemias

Best Practice and Research: Clinical Haematology

Volumn 14, Issue 3, 2001, Pages 573-591

  Hall, Georgina W ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

AML; Childhood MDS; Infant leukaemia; JMML; llq23; Monosomy 7

Indexed keywords

ALKYLATING AGENT; ANTHRACYCLINE DERIVATIVE; EPIPODOPHYLLOTOXIN DERIVATIVE; GRANULOCYTE COLONY STIMULATING FACTOR; GYRASE INHIBITOR; NEUROFIBROMIN;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; BLACKFAN DIAMOND ANEMIA; BLOOD ANALYSIS; BONE MARROW; BONE MARROW BIOPSY; CANCER GROWTH; CANCER SUSCEPTIBILITY; CHILD; CHILDHOOD LEUKEMIA; CHROMOSOME 11Q; CHROMOSOME 7; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME ARM; CHROMOSOME BREAKAGE; CHROMOSOME DELETION; CHRONIC MYELOID LEUKEMIA; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN SYNDROME; FANCONI ANEMIA; HUMAN; HUMAN CELL; INCIDENCE; INFANT; LEUKEMOGENESIS; MONOSOMY 7; MORPHOLOGY; MYELODYSPLASIA; MYELODYSPLASTIC SYNDROME; MYELOID LEUKEMIA; MYELOMONOCYTIC LEUKEMIA; NEUROFIBROMATOSIS; NEUTROPENIA; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; PROGNOSIS; SHWACHMAN SYNDROME; TRISOMY 8;

EID: 0034760207     PISSN: 15216926     EISSN: None     Source Type: Journal    
DOI: 10.1053/beha.2001.0155     Document Type: Article

References (111)

1. Pathology of acute myeloid leukemia
2. Biology and treatment of infant leukaemias
3. Chromosomal abnormalities in 478 children with acute myeloid leukemia: Clinical characteristics and treatment outcome in a cooperative Pediatric Oncology Group Study - POG 8821
4. Molecular cytogenetics of childhood hematological malignancies
5. Molecular cytogenetics of childhood acute myelogenous leukaemias
6. Dietary flavonoids and the MLL gene: A pathway to infant leukemia?
7. Prognostic factors in infants with acute myeloid leukemia
8. Backtracking leukemia to birth: Identification of clonotypic gene fusion sequences in neonatal blood spots
9. In utero rearrangements in the trithorax-related oncogene in infant leukaemias
10. Infant acute leukemias show the same biased distribution of ALL1 gene breaks as topoisomerase II related secondary acute leukemias
11. ALL-I gene rearrangements in DNA topoisomerase II inhibitor-related leukemia in children
12. Maternal exposure to potential inhibitors of DNA topoisomerase II and infant leukemia (United States): A report from the Children's Cancer Group
13. Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia
14. t(I;22)(p13;q13) in four children with acute megakaryoblastic leukemia (M7), two with Down syndrome
15. Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia
16. A new recurrent translocation, t(5;11)(q35;p15.5), associated with del(5q) in childhood acute myeloid leukemia. The UK Cancer Cytogenetics Group (UKCCG)
17. A novel gene is fused in NUP98 in the t(5;11)(q35;p15.5) in de novo childhood AML
18. t(7;12)(q36;p13), a new recurrent translocation involving ETV6 in infant leukaemia
19. Childhood Monosomy 7: Epidemiology, biology and mechanistic implications
20. Monosomy 7 in childhood: A myeloproliferative disorder
21. Myelodysplastic syndrome, juvenile myelomonocytic leukemia, and acute myeloid leukemia associated with complete or partial monosomy 7
22. Monosomy 7 and 7q- associated with myeloid malignancy
23. Evidence implicating heterozygous deletion of chromosome 7 in the pathogenesis of familial leukaemia associated with monosomy 7
24. Therapy-related myelodysplastic syndrome and acute myeloid leukemia in children: Correlation between chromosomal abnormalities and prior therapy
25. Cytogenetic and molecular delineation of a region of chromosome 7 commonly deleted in malignant myeloid disease
26. Delineation of multiple deleted regions in 7q in myeloid disorders
27. Molecular cytogenetic characterization of a critical region in bands 7q35-q36 commonly deleted in malignant myeloid disorders
28. Instability of chromosome 7 in colony forming cells of patients with aplastic anemia
29. Myelodysplastic syndrome and acute myelogenous leukemia as a late clonal complication in children with acquired aplastic anemia
30. Transformation of severe aplastic anemia to myelodysplastic syndrome with monosomy 7 in a patient who achieved transfusion independence after immunosuppressive therapy
31. Transient Monosomy 7
32. Familial acute myeloid leukemia with monosomy 7: Late onset and involvement of a multipotential progenitor cell
33. Topoisomerase II inhibitor-related acute myeloid leukaemia
34. Epipodophyllotoxin-related acute myeloid leukaemia
35. Breast cancer and other secondary neoplasms after childhood Hodgkin's disease
36. Increased frequency of dicentric chromosomes in therapy-related MDS and AML compared to de novo disease is significantly related to previous treatment with alkylating agents and suggests a specific susceptibility breakage at the centromere
37. MLL fusion genes in the 11q23 acute leukemias
38. Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: Correlation with scaffold attachment regions and topoisomerase consensus binding sites
39. Pseudo-rearrangement of the MLL gene at chromosome 11q23: A cautionary note on genotype analysis of leukaemia patients
40. DNA cleavage within the MLL breakpoint cluster region is a specific event which occurs as part of higher-order chromatin fragmentation during the initial stages of apoptosis
41. Secondary acute myeloblastic leukaemia (AML) (expressing 11q23 mutation) occurring 11 months after chemotherapy/radiotherapy for paediatric non-Hodgkin lymphoma
42. t(9;11)(p22;p15) in acute myeloid leukemia results in a fusion between NUO98 and the gene encoding transcriptional coactivators p52 and p75-lens epithelium-derived growth factor (LEDGF)
43. Potential role for DNA topoisomerase II poisons in the generation of t(11;20)(p15;q11) translocations
44. The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9
45. Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia
46. The inv(11)(p15q22) chromosome translocation of de novo and therapy-related myeloid malignancies results in fusion of the nucleoporin gene, NUP98, with the putative RNA helicase gene, DDX10
47. NUP98-HOXD13 gene fusion in therapy-related acute myelogenous leukemia
48. The (4;11)(q21;p15) translocation fuses the NUP98 and RAPIGDSI genes and is recurrent in T-cell acute lymphocytic leukemia
49. NUP98 is fused to PMXI homeobox gene in human acute myelogenous leukemia with chromosome translocation t(1;11)(q23;p15)
50. 11p15 translocations involving the NUP98 gene in childhood therapy-related acute myeloid leukemia myelodysplastic syndrome
51. Neuroblastoma and treatment-related myelodysplasia leukemia: The Memorial Sloan-Kettering experience and a literature review
52. Transient therapy-related myelodysplastic syndrome associated with monosomy 7 and 11q23 translocation
53. Myelodysplastic syndrome during recombinant human growth hormone supplementation after treatment for neuroblastoma
54. Leukemia in Down's syndrome
55. Survival from acute non-lymphocytic leukaemia. 1971-1988: A population based study
56. Chromosome 7 abnormalities in children with Down syndrome and preleukemia
57. Myelodysplastic syndromes
58. Cryptic deletions and inversions of chromosome 21 in a phenotypically normal infant with transient abnormal myelopoiesis: A molecular cytogenetic study
59. Transient abnormal myelopoiesis of infancy associated with trisomy 21
60. Additional chromosome abnormalities in transient abnormal myelopoiesis in Down's syndrome patients
61. Deletions of chromosome 21 restricted to the leukemic cells of children with Down syndrome and leukemia
62. Overexpression of bcl-2 in transient abnormal myelopoiesis associated with Down syndrome
63. Constitutional trisomy 8 and myelodysplasia: Report of a case and review of the literature
64. Chronic myelomonocytic leukaemia in a child with constitutional partial trisomy 8 mosaicism
65. Shwachman's syndrome
66. Haematological abnormalities in Shwachman-Diamond syndrome
67. Inherited bone marrow failure syndromes
68. Malignant myeloid transformation with isochromosome 7q in Shwachman-Diamond syndrome
69. Shwachman-Diamond syndrome with exocrine pancreatic dysfunction and bone marrow failure maps to the centromeric region of chromosome 7
70. Diamond-Blackfan anemia. Natural history and sequelae of treatment
71. Pentasomy 21 in leukemia complicating Diamond-Blackfan anemia
72. Clinical and laboratory evidence for a trilineage haematopoietic defect in patients with refractory Diamond-Blackfan anaemia
73. Diamond-Blackfan anaemia
74. The genetics of Fanconi's anaemia
75. Myelodysplastic syndrome associated with monosomy 7 in a child with Bloom syndrome
76. Inherited bone marrow failure syndromes
77. Hematologic abnormalities in Fanconi anemia: An International Fanconi Anemia Registry study
78. Fanconi anemia: Myelodysplasia as a predictor of outcome
79. Accelerated telomere shortening and telomerase activation in Fanconi's anaemia
80. Long-term safety of treatment with recombinant human granulocyte colony-stimulating factor (r-metHuG-CSF) in patients with severe congenital neutropenias
81. Mutations in the gene for the granulocyte-colony-stimulating factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia
82. Development of AML/MDS in a subset of patients (PTS) with severe chronic neutropenia (SCN)
83. Monosomy 7 and activating RAS mutations accompany malignant transformation in patients with congenital neutropenia
84. Myelodysplasia and acute myeloid leukemia in cases of aplastic anaemia and congenital neutropenia following G-CSF administration
85. Juvenile myelomonocytic leukemia
86. Acute leukemia as a natural sequel to primary thrombocythemia
87. CD7, CD34-positive stem cell leukemia arising in agnogenic myeloid metaplasia
88. Primary hemorrhagic thrombocythemia
89. A syndrome of lymphoblastic lymphoma, eosinophilia, and myeloid hyperplasia malignancy associated with t(8;13)(p11;q11): Description of a distinctive clinicopathologic entity
90. Chronic myelomonocytic leukaemia with t(8;9)(p11;q34) in childhood: An example of the 8p 11 myeloproliferative disorder?
91. Childhood myelodysplastic syndrome in Denmark: Incidence and predisposing conditions
92. Paediatric myelodysplasia
93. A case of myelodysplasia with eosinophilia having a translocation t(5;12)(q31;q13) restricted to myeloid cells but not involving eosinophils
94. Differentiating juvenile myelomonocytic leukemia from infectious disease
95. Loss of the normal NFI allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders
96. Chronic myelomonocytic leukemia in childhood: A retrospective analysis of 110 cases. European Working Group on Myelodysplastic Syndromes in Childhood (EWOG-MDS)
97. Persistent Epstein-Barr virus infection mimicking juvenile chronic myelogeneous leukemia: Immunologic and hematologic studies
98. Pediatric myelodysplasia: A study of 68 children and a new prognostic scoring system
99. Clonality in juvenile chronic myelogenous leukemia
100. Pattern of hematopoietic lineage involvement in children with neurofibromatosis, type 1 and malignant myeloid disorders
101. RAS mutations and clonality analysis in children with juvenile myelomonocytic leukemia (JMML)
102. Selective hypersensitivity to granulocyte-macrophage colony-stimulating factor by juvenile chronic myeloid leukaemia hematopoietic progenitors
103. Genetic analysis is consistent with the hypothesis that NFI limits myeloid cell growth through p21ras
104. Mutations of the ras proto-oncogenes in childhood monosomy 7
105. Abnormalities of the p53 gene in juvenile myelomonocytic leukaemia
106. Myelodysplastic and myeloproliferative disorders of childhood: A study of 167 patients
107. Chromosome pattern in juvenile chronic myelogenous leukemia. myelodysplastic syndrome, and acute leukemia associated with neurofibromatosis
108. The NFI gene in myelopoiesis and childhood myelodysplastic syndromes
109. Mutations of the NFI gene in children with juvenile myleomonocytic leukemia without clinical evidence of neurofibromatosis, type I
110. Homozygous inactivation of the NFI gene in bone marrow cells from children with neurofibromatosis type I and malignant myeloid disorders
111. Fusion of the homeobox gene HLXB9 and the ETV6 gene in infant acute myeloid leukemias with the t(7;12)(q36;p13)