CodY is required for nutritional repression of Bacillus subtilis genetic competence

Journal of Bacteriology

Volumn 178, Issue 20, 1996, Pages 5910-5915

  Serror, Pascale ^a,b   Sonenshein, Abraham L ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CEMAGREF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BACTERIAL DNA; DEOXYRIBONUCLEASE I; GENE PRODUCT; PLASMID DNA;

ARTICLE; BACILLUS SUBTILIS; BACTERIUM CULTURE; CULTURE MEDIUM; DNA FOOTPRINTING; ENZYME ASSAY; GENE MUTATION; GENE REPRESSION; GENETIC TRANSFORMATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REGULATOR GENE;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS);

EID: 0029837946     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.178.20.5910-5915.1996     Document Type: Article

References (47)

1. Albano, M., J. Hahn, and D. Dubnau. 1987. Expression of competence genes in Bacillus subtilis. J. Bacteriol. 169:3110-3117.
2. Atkinson, M. R., and S. H. Fisher. 1991. Identification of genes and gene products whose expression is activated during nitrogen-limited growth in Bacillus subtilis. J. Bacteriol. 173:23-27.
3. Atkinson, M. R., L. V. Wray, and S. H. Fisher. 1990. Regulation of histidine and proline degradation enzymes by amino acid availability in Bacillus subtilis. J. Bacteriol. 172:4758-4765.
4. Belitsky, B. R., P. J. Janssen, and A. L. Sonenshein. 1995. Sites required for GltC-dependent regulation of Bacillus subtilis glutamate synthase expression. J. Bacteriol. 177:5686-5695.
5. D'Souza, C., M. M. Nakano, N. Corbell, and P. Zuber. 1993. Amino-acylation site mutations in amino acid-activating domains of surfactin synthetase: effects on surfactin production and competence development in Bacillus subtilis. J. Bacteriol. 175:3502-3510.
6. D'Souza, C., M. M. Nakano, and P. Zuber. 1994. Identification of comS, a gene of the srfA operon that regulates the establishment of genetic competence in Bacillus subtilis. Proc. Natl. Acad. Sci. USA 91:9397-9401.
7. Dubnau, D. 1993. Genetic exchange and homologous recombination, p. 555-584. In A. L. Sonenshein, J. A. Hoch, and R. Losick (ed.), Bacillus subtilis and other gram-positive bacteria: biochemistry, physiology, and molecular genetics. American Society for Microbiology, Washington, D.C.
8. Dubnau, D., and R. Davidoff-Abelson. 1971. Fate of transforming DNA following uptake by competent Bacillus subtilis. J. Mol. Biol. 56:209-211.
9. Dubnau, D., J. Hahn, L. Kong, M. Roggiani, and Y. Weinrauch. 1991. Genetic competence as a post-exponential global response. Semin. Dev. Biol. 2:3-11.
10. Dubnau, D., and M. Roggiani. 1990. Growth medium-independent genetic competence mutants of Bacillus subtilis. J. Bacteriol. 172:4048-4055.
11. Fisher, S. H., K. Rohrer, and A. E. Ferson. 1996. Role of CodY in regulation of the Bacillus subtilis hut operon. J. Bacteriol. 178:3779-3784.
12. Fouet, A., and A. L. Sonenshein. 1990. A target for carbon source-dependent negative regulation of the citB promoter of Bacillus subtilis. J. Bacteriol. 172:835-844.
13. Grossman, A. D. 1995. Genetic networks controlling the initiation of sporulation and the development of genetic competence in Bacillus subtilis. Annu. Rev. Genet. 29:477-508.
14. Guillen, N., Y. Weinrauch, and D. Dubnau. 1989. Cloning and characterization of the regulatory Bacillus subtilis competence genes, comA and comB. J. Bacteriol. 171:5353-5361.
15. Hahn, J., and D. Dubnau. 1991. Growth stage signal transduction and the requirements for srfA induction in development of competence. J. Bacteriol. 173:7275-7282.
16. Hahn, J., L. Kong, and D. Dubnau. 1994. The regulation of competence transcription factor synthesis constitutes a critical control point in the regulation of competence in Bacillus subtilis. J. Bacteriol. 176:5753-5761.
17. Hamoen, L. Personal communication.
18. Hamoen, L. W., H. Eshuis, J. Jongbloed, G. Venema, and D. van Sinderen. 1995. A small gene, designated comS, located within the coding region of the fourth amino acid-activation domain of srfA, is required for competence development in Bacillus subtilis. Mol. Microbiol. 15:55-63.
19. Kong, L., and D. Dubnau. 1994. Regulation of competence-specific gene expression by Mec-mediated protein-protein interaction in Bacillus subtilis. Proc. Natl. Acad. Sci. USA 91:5793-5797.
20. Kong, L., K. J. Siranosian, A. D. Grossman, and D. Dubnau. 1993. Sequence and properties of mecA, a negative regulator of genetic competence in Bacillus subtilis. Mol. Microbiol. 9:365-373.
21. Magnuson, R., J. Solomon, and A. D. Grossman. 1994. Biochemical and genetic characterization of a competence pheromone from B. subtilis. Cell 77:207-216.
22. Marahiel, M. A. Personal communication.
23. Mathiopoulos, C., J. P. Mueller, F. J. Slack, C. G. Murphy, S. Patankar, G. Bukusoglu, and A. L. Sonenshein. 1991. A Bacillus subtilis dipeptide transport system expressed early during sporulation. Mol. Microbiol. 5:1903-1913.
24. Msadek, T., F. Kunst, and G. Rapoport. 1994. MecB of Bacillus subtilis, a member of the ClpC ATPase family, is a pleiotropic regulator controlling competence gene expression and growth at high temperature. Proc. Natl. Acad. Sci. USA 91:5788-5792.
25. Mueller, J. P., G. Bukusoglu, and A. L. Sonenshein. 1992. Transcriptional regulation of Bacillus subtilis glucose starvation-inducible genes: control of gsiA by the ComP-ComA signal transduction system. J. Bacteriol. 174:4361-4373.
26. Nakano, M. M., L. Xia, and P. Zuber. 1991. Transcription initiation of the srfA operon, which is controlled by the comP-comA signal transduction system in Bacillus subtilis. J. Bacteriol. 173:5487-5493.
27. Nakano, M. M., and P. Zuber. 1991. The primary role of ComA in establishment of the competence state in Bacillus subtilis is to activate expression of srfA. J. Bacteriol. 173:7269-7274.
28. Perego, M., C. Hanstein, K. M. Welsh, T. Djavakhishvili, P. Glaser, and J. A. Hoch. 1994. Multiple protein-aspartate phosphatases provide a mechanism for the integration of diverse signals in the control of development in B. subtilis. Cell 79:1047-1055.
29. Perego, M., C. F. Higgins, S. R. Pearce, M. P. Gallagher, and J. A. Hoch. 1991. The oligopeptide transport system of Bacillus subtilis plays a role in the initiation of sporulation. Mol. Microbiol. 5:173-185.
30. Perego, M., G. B. Spiegelman, and J. A. Hoch. 1988. Structure of the gene for the transition state regulator, abrB: regulator synthesis is controlled by spoOA sporulation gene in Bacillus subtilis. Mol. Microbiol. 2:689-699.
31. Roggiani, M., and D. Dubnau. 1993. ComA, a phosphorylated response regulator protein of Bacillus subtilis, binds to the promoter region of srfA. J. Bacteriol. 175:3182-3187.
32. Rudner, D. Z., J. R. LeDeaux, K. Ireton, and A. D. Grossman. 1991. The spo0K locus of Bacillus subtilis is homologous to the oligopeptide permease locus and is required for sporulation and competence. J. Bacteriol. 173:1388-1398.
33. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
34. Serror, P., and A. L. Sonenshein. 1996. Interaction of CodY, a novel Bacillus subtilis DNA-binding protein, with the dpp promoter region. Mol. Microbiol. 20:843-852.
35. Serror, P., and A. L. Sonenshein. Unpublished results.
36. Slack, F. J., J. P. Mueller, and A. L. Sonenshein. 1993. Mutations that relieve nutritional repression of the Bacillus subtilis dipeptide permease operon. J. Bacteriol. 175:4605-4614.
37. Slack, F. J., J. P. Mueller, M. A. Strauch, C. Mathiopoulos, and A. L. Sonenshein. 1991. Transcriptional regulation of a Bacillus subtilis dipeptide transport operon. Mol. Microbiol. 5:1915-1925.
38. Slack, F. J., P. Serror, E. Joyce, and A. L. Sonenshein. 1995. A gene required for nutritional repression of the Bacillus subtilis dipeptide permease operon. Mol. Microbiol. 15:689-702.
39. Solomon, J., R. Magnuson, A. Srivastava, and A. D. Grossman. 1995. Convergent sensing pathways mediate response to two extracellular competence factors in Bacillus subtilis. Genes Dev. 9:547-558.
40. Steinmetz, M., and R. Richter. 1994. Plasmids designed to alter the antibiotic resistance expressed by insertion mutations in Bacillus subtilis, through in vivo recombination. Gene 142:79-83.
41. Strauch, M. A. 1993. AbrB, a transition state regulator, p. 757-764. In A. L. Sonenshein, J. A. Hoch, and R. Losick (ed.), Bacillus subtilis and other gram-positive bacteria: biochemistry, physiology, and molecular genetics. American Society for Microbiology, Washington, D.C.
42. van Sinderen, D., A. Luttinger, L. Kong, D. Dubnau, G. Venema, and L. Hamoen. 1995. comK encodes the competence transcription factor, the key regulatory protein for competence development in Bacillus subtilis. Mol. Microbiol. 15:455-462.
43. van Sinderen, D., A. ten Berge, B. J. Hayema, L. Hamoen, and G. Venema. 1994. Molecular cloning and sequence of comK, a gene required for genetic competence in Bacillus subtilis. Mol. Microbiol. 11:695-703.
44. van Sinderen, D., and G. Venema. 1994. comK acts as an autoregulatory control switch in the signal transduction route to competence in Bacillus subtilis. J. Bacteriol. 176:5762-5770.
45. van Sinderen, D., S. Withoff, H. Boels, and G. Venema. 1990. Isolation and characterization of comL, a transcription unit involved in competence development of Bacillus subtilis. Mol. Gen. Genet. 224:396-404.
46. Vasantha, N., and E. Freese. 1979. Enzyme changes during Bacillus subtilis sporulation caused by deprivation of guanine nucleotides. J. Bacteriol. 144: 1119-1125.
47. Young, F. E., and J. Spizizen. 1961. Physiological and genetic factors affecting transformation of Bacillus subtilis. J. Bacteriol. 81:823-829.