Pseudopackaging of adenovirus type 5 genomes into capsids containing the hexon proteins of adenovirus serotypes B, D, or E

Journal of Virology

Volumn 75, Issue 1, 2001, Pages 45-51

  Ostapchuk, P ^a   Hearing, P ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUTRALIZING ANTIBODY; VIRUS PROTEIN; VIRUS VECTOR;

ADENOVIRUS; ANTIGENICITY; ARTICLE; CYTOTOXIC T LYMPHOCYTE; DNA PACKAGING; GENE TARGETING; HUMORAL IMMUNITY; IMMUNE RESPONSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TEMPERATURE SENSITIVE MUTANT; TRANSGENE; VIRION; VIRUS ASSEMBLY; VIRUS CAPSID; VIRUS GENOME; VIRUS PARTICLE;

ADENOVIRIDAE; BASE SEQUENCE; CAPSID; DNA, VIRAL; GENOME, VIRAL; MOLECULAR SEQUENCE DATA; SEROTYPING; VIRUS ASSEMBLY;

EID: 0034751122     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.1.45-51.2001     Document Type: Article

References (48)

1. Phylogenetic relationships among adenovirus serotypes
2. Poly(lactic-glycolic) acid copolymer encapsulation of recombinant adenovirus reduces immunogenicity in vivo
3. Adenovirus vectors for gene delivery
4. Suppression of the immune response to an adenovirus vector and enhancement of intratumoral transgene expression by low-dose etoposide
5. Gene transfer by adenovectors
6. Interactions between the immune system and gene therapy vectors: Bidirectional regulation of response and expression
7. Assembly of adenovirus major capsid protein is mediated by a nonvirion protein
8. Immune responses to adenovirus and adeno-associated virus in humans
9. Repeated administration of adenoviral vectors in lungs of human CD4 transgenic mice treated with a nondepleting CD4 antibody
10. Gene therapy with recombinant adenovirus vectors: Evaluation of the host immune response
11. Transient immunosuppression with 15-deoxyspergualin prolongs reporter gene expression and reduces humoral immune response after adenoviral gene transfer
12. Analysis of 15 adenovirus hexon proteins reveals the location and structure of seven hypervariable regions containing serotype-specific residues
13. Structure, function and specificity of the DNA packaging signals in double-stranded DNA viruses
14. Adenovirus type 5 and 7 capsid chimera: Fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes
15. Construction and characterization of hexon-chimeric adenoviruses: Specification of adenovirus serotype
16. Characteristics of a human cell line transformed by DNA from human adenovirus type 5
17. Variability of human systemic humoral immune responses to adenovirus gene transfer vectors administered to different organs
18. Adenoviruses
19. Oral tolerization to adenoviral antigens permits long-term gene expression using recombinant adenoviral vectors
20. Blunting of immune responses to adenoviral vectors in mouse liver and lung with CTLA4Ig
21. Transient immunosuppression with deoxyspergualin improves longevity of transgene expression and ability to readminister adenoviral vector to the mouse lung
22. Humoral and cellular immune responses of nonhuman primates to long-term repeated lung exposure to Ad2/CFTR-2
23. Circumventing the immune response to adenovirus-mediated gene therapy
24. Characterization of a temperature-sensitive, hexon transport mutant of type 5 adenovirus
25. Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4Ig administration
26. High-capacity adenoviral vectors for gene transfer and somatic gene therapy
27. Transient immunosuppression by FK506 permits a sustained high-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscles of adult dystrophic (mdx) mice
28. Circumvention of anti-adenovirus neutralizing immunity by administration of an adenoviral vector of an alternate serotype
29. 'Sero-switch' adenovirus-mediated in vivo gene transfer: Circumvention of anti-adenovirus humoral immune defenses against repeat adenovirus vector administration by changing the adenovirus sero-type
30. Adenovirus protein-protein interactions: Hexon and protein VI
31. Coloration of silver-stained protein bands in polyacrylamide gels is caused by light scattering from silver grains of characteristic sizes
32. Circumvention of vector-specific neutralizing antibody response by alternating use of human and non-human adenoviruses: Implications in gene therapy
33. Structural and functional diversity of adenovirus capsid components
34. PEGylation of adenovirus with retention of infectivity and protection from neutralizing antibody in vitro and in vivo
35. Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration
36. Type-specific epitope locations revealed by X-ray crystallographic study of adenovirus type 5 hexon
37. Identification and characterization of an immunologically conserved adenovirus early region 11,000 Mr protein and its association with the nuclear matrix
38. Cellular components interact with adenovirus type 5 minimal DNA packaging domains
39. Worldwide epidemiology of human adenovirus infections
40. Adenoviridae: The viruses and their replication
41. Adenovirus type 40 and 41 growth in vitro: Host range diversity reflected by differences in patterns of DNA replication
42. Immune responses to transgene-encoded protehns limit the stability of gene expression after injection of replication-defective adenovirus vectors
43. Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
44. Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy
45. Transient subversion of CD40 ligand function diminishes immune responses to adenovirus vectors in mouse liver and lung tissues
46. Role of viral antigens in destructive cellular immune responses to adenovirus vector-transduced cells in mouse lungs
47. Adenovirus-mediated gene transfer for cystic fibrosis: Quantitative evaluation of repeated in vivo administration to the lung