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Volumn 1, Issue 1, 2000, Pages 18-30

Type-Specific Epitope Locations Revealed by X-Ray Crystallographic Study of Adenovirus Type 5 Hexon

Author keywords

Adenovirus; epitopes; gene therapy; hexon; X ray diffraction

Indexed keywords

CAPSID PROTEIN; EPITOPE; HEXON CAPSID PROTEIN, ADENOVIRUS; HYBRID PROTEIN; VIRUS ANTIGEN;

EID: 0033661024     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.1999.0001     Document Type: Article
Times cited : (140)

References (64)
  • 1
    • 0031667814 scopus 로고    scopus 로고
    • Characterization of intertype specific epitopes on adenovirus hexons
    • Ádám É., Nász I., Hudecz F., Lengyel A., Mezö G., Dobay O. Characterization of intertype specific epitopes on adenovirus hexons. Arch. Virol. 143:1998;1669-1682.
    • (1998) Arch. Virol. , vol.143 , pp. 1669-1682
    • Ádám, É.1    Nász, I.2    Hudecz, F.3    Lengyel, A.4    Mezö, G.5    Dobay, O.6
  • 2
    • 0020327029 scopus 로고
    • A common sequence in the inverted terminal repetitions of human and avian adenoviruses
    • Aleström P., Stenlund A., Li P., Pettersson U. A common sequence in the inverted terminal repetitions of human and avian adenoviruses. Gene. 18:1982;193-197.
    • (1982) Gene , vol.18 , pp. 193-197
    • Aleström, P.1    Stenlund, A.2    Li, P.3    Pettersson, U.4
  • 3
    • 0028151167 scopus 로고
    • The refined crystal structure of hexon, the major coat protein of adenovirus type 2, at 2.9 Å resolution
    • Athappilly F. K., Murali R., Rux J. J., Cai Z., Burnett R. M. The refined crystal structure of hexon, the major coat protein of adenovirus type 2, at 2.9 Å resolution. J. Mol. Biol. 242:1994;430-455.
    • (1994) J. Mol. Biol. , vol.242 , pp. 430-455
    • Athappilly, F.K.1    Murali, R.2    Rux, J.J.3    Cai, Z.4    Burnett, R.M.5
  • 4
    • 0027938740 scopus 로고
    • Phylogenetic relationships among adenovirus serotypes
    • Bailey A., Mautner V. Phylogenetic relationships among adenovirus serotypes. Virology. 205:1994;438-452.
    • (1994) Virology , vol.205 , pp. 438-452
    • Bailey, A.1    Mautner, V.2
  • 5
    • 0033578669 scopus 로고    scopus 로고
    • Viral evolution revealed by bacteriophage PRD1 and human adenovirus coat protein structures
    • Benson S. D., Bamford J. K. H., Bamford D. H., Burnett R. M. Viral evolution revealed by bacteriophage PRD1 and human adenovirus coat protein structures. Cell. 98:1999;825-833.
    • (1999) Cell , vol.98 , pp. 825-833
    • Benson, S.D.1    Bamford, J.K.H.2    Bamford, D.H.3    Burnett, R.M.4
  • 7
    • 85027779617 scopus 로고
    • A system for collection and on-line integration of X-ray diffraction data from a multiwire area detector
    • Blum M., Metcalf P., Harrison S. C., Wiley D. C. A system for collection and on-line integration of X-ray diffraction data from a multiwire area detector. J. Appl. Crystallogr. 20:1987;235-242.
    • (1987) J. Appl. Crystallogr. , vol.20 , pp. 235-242
    • Blum, M.1    Metcalf, P.2    Harrison, S.C.3    Wiley, D.C.4
  • 8
    • 0026597444 scopus 로고
    • Free R value: A novel statistical quantity for assessing the accuracy of crystal structures
    • Brünger A. T. Free R value: A novel statistical quantity for assessing the accuracy of crystal structures. Nature. 355:1992;472-475.
    • (1992) Nature , vol.355 , pp. 472-475
    • Brünger, A.T.1
  • 9
    • 0029561893 scopus 로고
    • DNA packaging orders the membrane of bacteriophage PRD1
    • Butcher S. J., Bamford D. H., Fuller S. D. DNA packaging orders the membrane of bacteriophage PRD1. EMBO J. 14:1995;6078-6086.
    • (1995) EMBO J. , vol.14 , pp. 6078-6086
    • Butcher, S.J.1    Bamford, D.H.2    Fuller, S.D.3
  • 10
    • 0020405893 scopus 로고
    • Assembly of adenovirus major capsid protein is mediated by a nonvirion protein
    • Cepko C. L., Sharp P. A. Assembly of adenovirus major capsid protein is mediated by a nonvirion protein. Cell. 31:1982;407-415.
    • (1982) Cell , vol.31 , pp. 407-415
    • Cepko, C.L.1    Sharp, P.A.2
  • 11
    • 0026551721 scopus 로고
    • The sequence of the genome of adenovirus type 5 and its comparison with the genome of adenovirus type 2
    • Chroboczek J., Bieber F., Jacrot B. The sequence of the genome of adenovirus type 5 and its comparison with the genome of adenovirus type 2. Virology. 186:1992;280-285.
    • (1992) Virology , vol.186 , pp. 280-285
    • Chroboczek, J.1    Bieber, F.2    Jacrot, B.3
  • 12
    • 0028103275 scopus 로고
    • The CCP4 Suite: Programs for protein crystallography
    • Collaborative Computational Project Number 4
    • Collaborative Computational Project Number 4. The CCP4 Suite: Programs for protein crystallography. Acta Crystallogr. D50:1994;760-763.
    • (1994) Acta Crystallogr. , vol.50 , pp. 760-763
  • 13
    • 0015222935 scopus 로고
    • Characterization of crystals of type 5 adenovirus hexon
    • Cornick G., Sigler P. B., Ginsberg H. S. Characterization of crystals of type 5 adenovirus hexon. J. Mol. Biol. 57:1971;397-401.
    • (1971) J. Mol. Biol. , vol.57 , pp. 397-401
    • Cornick, G.1    Sigler, P.B.2    Ginsberg, H.S.3
  • 14
    • 0030066708 scopus 로고    scopus 로고
    • Analysis of 15 adenovirus hexon proteins reveals the location and structure of seven hypervariable regions containing serotype-specific residues
    • Crawford-Miksza L., Schnurr D. P. Analysis of 15 adenovirus hexon proteins reveals the location and structure of seven hypervariable regions containing serotype-specific residues. J. Virol. 70:1996;1836-1844.
    • (1996) J. Virol. , vol.70 , pp. 1836-1844
    • Crawford-Miksza, L.1    Schnurr, D.P.2
  • 15
    • 0028144562 scopus 로고
    • Expression of a foreign epitope on the surface of the adenovirus hexon
    • Crompton J., Toogood C. I., Wallis N., Hay R. T. Expression of a foreign epitope on the surface of the adenovirus hexon. J. Gen. Virol. 75:1994;133-139.
    • (1994) J. Gen. Virol. , vol.75 , pp. 133-139
    • Crompton, J.1    Toogood, C.I.2    Wallis, N.3    Hay, R.T.4
  • 16
    • 0028891941 scopus 로고
    • Immunological adenovirus variant strains of subgenus D: Comparison of the hexon and fiber sequences
    • Eiz B., Adrian T., Pring-Åkerblom P. Immunological adenovirus variant strains of subgenus D: Comparison of the hexon and fiber sequences. Virology. 213:1995;313-320.
    • (1995) Virology , vol.213 , pp. 313-320
    • Eiz, B.1    Adrian, T.2    Pring-Åkerblom, P.3
  • 17
    • 0027609916 scopus 로고
    • SETOR: Hardware lighted three-dimensional solid model representations of macromolecules
    • Evans S. V. SETOR: Hardware lighted three-dimensional solid model representations of macromolecules. J. Mol. Graph. 11:1993;134-138.
    • (1993) J. Mol. Graph. , vol.11 , pp. 134-138
    • Evans, S.V.1
  • 18
    • 0015222959 scopus 로고
    • Structural proteins of adenovirus. V. Size and structure of the adenovirus type 2 hexon
    • Franklin R. M., Pettersson U., Åkervall K., Strandberg B., Philipson L. Structural proteins of adenovirus. V. Size and structure of the adenovirus type 2 hexon. J. Mol. Biol. 57:1971;383-395.
    • (1971) J. Mol. Biol. , vol.57 , pp. 383-395
    • Franklin, R.M.1    Pettersson, U.2    Åkervall, K.3    Strandberg, B.4    Philipson, L.5
  • 19
    • 0031743088 scopus 로고    scopus 로고
    • Construction and characterization of hexon-chimeric adenoviruses: Specification of adenovirus serotype
    • Gall J. G. D., Crystal R. G., Falck-Pedersen E. Construction and characterization of hexon-chimeric adenoviruses: Specification of adenovirus serotype. J. Virol. 72:1998;10260-10264.
    • (1998) J. Virol. , vol.72 , pp. 10260-10264
    • Gall, J.G.D.1    Crystal, R.G.2    Falck-Pedersen, E.3
  • 20
    • 0029869840 scopus 로고    scopus 로고
    • Adenovirus type 5 and 7 capsid chimera: Fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes
    • Gall J., Kass-Eisler A., Leinwand L., Falck-Pedersen E. Adenovirus type 5 and 7 capsid chimera: Fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes. J. Virol. 70:1996;2116-2123.
    • (1996) J. Virol. , vol.70 , pp. 2116-2123
    • Gall, J.1    Kass-Eisler, A.2    Leinwand, L.3    Falck-Pedersen, E.4
  • 22
    • 0026401671 scopus 로고
    • Antigenic relationships among the 47 human adenoviruses determined in reference horse antisera
    • Hierholzer J. C., Stone Y. O., Broderson J. R. Antigenic relationships among the 47 human adenoviruses determined in reference horse antisera. Arch. Virol. 121:1991;179-197.
    • (1991) Arch. Virol. , vol.121 , pp. 179-197
    • Hierholzer, J.C.1    Stone, Y.O.2    Broderson, J.R.3
  • 23
    • 0028205447 scopus 로고
    • Enlarged representative set of protein structures
    • Hobohm U., Sander C. Enlarged representative set of protein structures. Protein Sci. 3:1994;522-524.
    • (1994) Protein Sci. , vol.3 , pp. 522-524
    • Hobohm, U.1    Sander, C.2
  • 24
    • 0030994260 scopus 로고    scopus 로고
    • Adenovirus type 5 fiber knob binds to MHC class I α2 domain at the surface of human epithelial and B lymphoblastoid cells
    • Hong S. S., Karayan L., Tournier J., Curiel D. T., Boulanger P. A. Adenovirus type 5 fiber knob binds to MHC class I α2 domain at the surface of human epithelial and B lymphoblastoid cells. EMBO J. 16:1997;2294-2306.
    • (1997) EMBO J. , vol.16 , pp. 2294-2306
    • Hong, S.S.1    Karayan, L.2    Tournier, J.3    Curiel, D.T.4    Boulanger, P.A.5
  • 26
    • 0030039296 scopus 로고    scopus 로고
    • PROMOTIF - A program to identify and analyze structural motifs in proteins
    • Hutchinson E. G., Thornton J. M. PROMOTIF - A program to identify and analyze structural motifs in proteins. Protein Sci. 5:1996;212-220.
    • (1996) Protein Sci. , vol.5 , pp. 212-220
    • Hutchinson, E.G.1    Thornton, J.M.2
  • 27
    • 84889120137 scopus 로고
    • Improved methods for building protein models in electron density maps and the location of errors in these models
    • Jones T. A., Zou J.-Y., Cowan S. W., Kjeldgaard M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A47:1991;110-119.
    • (1991) Acta Crystallogr. , vol.47 , pp. 110-119
    • Jones, T.A.1    Zou, J.-Y.2    Cowan, S.W.3    Kjeldgaard, M.4
  • 28
    • 0018895859 scopus 로고
    • Limited proteolysis and a reactive cysteine residue define accessible regions in the native conformation of the adenovirus hexon protein
    • Jörnvall H., Philipson L. Limited proteolysis and a reactive cysteine residue define accessible regions in the native conformation of the adenovirus hexon protein. Eur. J. Biochem. 104:1980;237-247.
    • (1980) Eur. J. Biochem. , vol.104 , pp. 237-247
    • Jörnvall, H.1    Philipson, L.2
  • 29
    • 85046526624 scopus 로고
    • Evaluation of single-crystal X-ray diffraction data from a position-sensitive detector
    • Kabsch W. Evaluation of single-crystal X-ray diffraction data from a position-sensitive detector. J. Appl. Crystallogr. 21:1988;916-924.
    • (1988) J. Appl. Crystallogr. , vol.21 , pp. 916-924
    • Kabsch, W.1
  • 31
    • 0021214407 scopus 로고
    • Adenovirus hexon: Sequence comparison of subgroup C serotypes 2 and 5
    • Kinloch R., Mackay N., Mautner V. Adenovirus hexon: Sequence comparison of subgroup C serotypes 2 and 5. J. Biol. Chem. 259:1984;6431-6436.
    • (1984) J. Biol. Chem. , vol.259 , pp. 6431-6436
    • Kinloch, R.1    MacKay, N.2    Mautner, V.3
  • 33
    • 0026244229 scopus 로고
    • MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
    • Kraulis P. J. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures. J. Appl. Crystallogr. 24:1991;946-950.
    • (1991) J. Appl. Crystallogr. , vol.24 , pp. 946-950
    • Kraulis, P.J.1
  • 34
    • 0030857432 scopus 로고    scopus 로고
    • Hydropathic characteristics of adenovirus hexons
    • Li Q.-G., Lindman K., Wadell G. Hydropathic characteristics of adenovirus hexons. Arch. Virol. 142:1997;1307-1322.
    • (1997) Arch. Virol. , vol.142 , pp. 1307-1322
    • Li, Q.-G.1    Lindman, K.2    Wadell, G.3
  • 35
    • 0014329310 scopus 로고
    • The polypeptides of adenovirus. I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12
    • Maizel J. V. Jr., White D. O., Scharff M. D. The polypeptides of adenovirus. I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12. Virology. 36:1968;115-125.
    • (1968) Virology , vol.36 , pp. 115-125
    • Maizel J.V., Jr.1    White, D.O.2    Scharff, M.D.3
  • 36
    • 0029983685 scopus 로고    scopus 로고
    • "sero-switch" adenovirus-mediated in vivo gene transfer: Circumvention of anti-adenovirus humoral immune defenses against repeat adenovirus vector administration by changing the adenovirus serotype
    • Mastrangeli A., Harvey B. G., Yao J., Wolff G., Kovesdi I., Crystal R. G., Falck-Pedersen E. "Sero-switch" adenovirus-mediated in vivo gene transfer: Circumvention of anti-adenovirus humoral immune defenses against repeat adenovirus vector administration by changing the adenovirus serotype. Hum. Gene Ther. 7:1996;79-87.
    • (1996) Hum. Gene Ther. , vol.7 , pp. 79-87
    • Mastrangeli, A.1    Harvey, B.G.2    Yao, J.3    Wolff, G.4    Kovesdi, I.5    Crystal, R.G.6    Falck-Pedersen, E.7
  • 37
    • 0030815133 scopus 로고    scopus 로고
    • Raster3D: Photorealistic molecular graphics
    • Merritt E. A., Bacon D. J. Raster3D: Photorealistic molecular graphics. Methods Enzymol. 277:1997;505-524.
    • (1997) Methods Enzymol. , vol.277 , pp. 505-524
    • Merritt, E.A.1    Bacon, D.J.2
  • 38
    • 0014573011 scopus 로고
    • The structural and functional diversity of adenovirus capsid components
    • Norrby E. The structural and functional diversity of adenovirus capsid components. J. Gen. Virol. 5:1969;221-236.
    • (1969) J. Gen. Virol. , vol.5 , pp. 221-236
    • Norrby, E.1
  • 39
    • 0021112807 scopus 로고
    • Structure of tomato bushy stunt virus IV. The virus particle at 2.9 Å resolution
    • Olson A. J., Bricogne G., Harrison S. C. Structure of tomato bushy stunt virus IV. The virus particle at 2.9 Å resolution. J. Mol. Biol. 171:1983;61-93.
    • (1983) J. Mol. Biol. , vol.171 , pp. 61-93
    • Olson, A.J.1    Bricogne, G.2    Harrison, S.C.3
  • 40
    • 0000649842 scopus 로고    scopus 로고
    • Improved structure refinement through maximum likelihood
    • Pannu N. S., Read R. J. Improved structure refinement through maximum likelihood. Acta Crystallogr. A52:1996;659-668.
    • (1996) Acta Crystallogr. , vol.52 , pp. 659-668
    • Pannu, N.S.1    Read, R.J.2
  • 41
    • 0014436679 scopus 로고
    • Crystallization of an adenovirus protein (the hexon)
    • Pereira H. G., Valentine R. C., Russell W. C. Crystallization of an adenovirus protein (the hexon). Nature. 219:1968;946-947.
    • (1968) Nature , vol.219 , pp. 946-947
    • Pereira, H.G.1    Valentine, R.C.2    Russell, W.C.3
  • 42
    • 0027270579 scopus 로고
    • The hexon genes of adenoviruses of subgenus C: Comparison of the variable regions
    • Pring-Åkerblom P., Adrian T. The hexon genes of adenoviruses of subgenus C: Comparison of the variable regions. Res. Virol. 144:1993;117-127.
    • (1993) Res. Virol. , vol.144 , pp. 117-127
    • Pring-Åkerblom, P.1    Adrian, T.2
  • 43
    • 0028867144 scopus 로고
    • Sequence characterization and comparison of human adenovirus subgenus B and E hexons
    • Pring-Åkerblom P., Trijssenaar F. E., Adrian T. Sequence characterization and comparison of human adenovirus subgenus B and E hexons. Virology. 212:1995;232-236.
    • (1995) Virology , vol.212 , pp. 232-236
    • Pring-Åkerblom, P.1    Trijssenaar, F.E.2    Adrian, T.3
  • 45
    • 0023059423 scopus 로고
    • Three-dimensional structure of the adenovirus major coat protein hexon
    • Roberts M. M., White J. L., Grütter M. G., Burnett R. M. Three-dimensional structure of the adenovirus major coat protein hexon. Science. 232:1986;1148-1151.
    • (1986) Science , vol.232 , pp. 1148-1151
    • Roberts, M.M.1    White, J.L.2    Grütter, M.G.3    Burnett, R.M.4
  • 46
    • 0030032665 scopus 로고    scopus 로고
    • Adenovirus uncoating and nuclear establishment are not affected by weak base amines
    • Rodriguez E., Everitt E. Adenovirus uncoating and nuclear establishment are not affected by weak base amines. J. Virol. 70:1996;3470-3477.
    • (1996) J. Virol. , vol.70 , pp. 3470-3477
    • Rodriguez, E.1    Everitt, E.2
  • 47
    • 0000972520 scopus 로고
    • Isolation of a cytopathogenic agent from human adenoids undergoing spontaneous degeneration in tissue culture
    • Rowe W. P., Huebner R. J., Gillmore L. K., Parrott R. H., Ward T. G. Isolation of a cytopathogenic agent from human adenoids undergoing spontaneous degeneration in tissue culture. Proc. Soc. Exp. Biol. Med. 84:1953;570-573.
    • (1953) Proc. Soc. Exp. Biol. Med. , vol.84 , pp. 570-573
    • Rowe, W.P.1    Huebner, R.J.2    Gillmore, L.K.3    Parrott, R.H.4    Ward, T.G.5
  • 48
    • 0031903186 scopus 로고    scopus 로고
    • Circumvention of immunity to the adenovirus major coat protein hexon
    • Roy S., Shirley P. S., McClelland A., Kaleko M. Circumvention of immunity to the adenovirus major coat protein hexon. J. Virol. 72:1998;6875-6879.
    • (1998) J. Virol. , vol.72 , pp. 6875-6879
    • Roy, S.1    Shirley, P.S.2    McClelland, A.3    Kaleko, M.4
  • 50
    • 0022921876 scopus 로고
    • Linear DNA replication: Inverted terminal repeats of five closely related Escherichia coli bacteriophages
    • Savilahti H., Bamford D. H. Linear DNA replication: Inverted terminal repeats of five closely related Escherichia coli bacteriophages. Gene. 49:1986;199-205.
    • (1986) Gene , vol.49 , pp. 199-205
    • Savilahti, H.1    Bamford, D.H.2
  • 51
    • 0039226970 scopus 로고    scopus 로고
    • B.N. Fields, D.M. Knipe, & P.M. Howley. New York: Raven Press
    • Shenk T. Fields B. N., Knipe D. M., Howley P. M. Virology. 1996;2111-2148 Raven Press, New York.
    • (1996) Virology , pp. 2111-2148
    • Shenk, T.1
  • 52
    • 0023645549 scopus 로고
    • Refined structure of southern bean mosaic virus at 2.9 Å resolution
    • Silva A. M., Rossmann M. G. Refined structure of southern bean mosaic virus at 2.9 Å resolution. J. Mol. Biol. 197:1987;69-87.
    • (1987) J. Mol. Biol. , vol.197 , pp. 69-87
    • Silva, A.M.1    Rossmann, M.G.2
  • 53
    • 0026006259 scopus 로고
    • Image reconstruction reveals the complex molecular organization of adenovirus
    • Stewart P. L., Burnett R. M., Cyrklaff M., Fuller S. D. Image reconstruction reveals the complex molecular organization of adenovirus. Cell. 67:1991;145-154.
    • (1991) Cell , vol.67 , pp. 145-154
    • Stewart, P.L.1    Burnett, R.M.2    Cyrklaff, M.3    Fuller, S.D.4
  • 54
    • 0027184774 scopus 로고
    • Difference imaging of adenovirus: Bridging the resolution gap between X-ray crystallography and electron microscopy
    • Stewart P. L., Fuller S. D., Burnett R. M. Difference imaging of adenovirus: Bridging the resolution gap between X-ray crystallography and electron microscopy. EMBO J. 12:1993;2589-2599.
    • (1993) EMBO J. , vol.12 , pp. 2589-2599
    • Stewart, P.L.1    Fuller, S.D.2    Burnett, R.M.3
  • 55
    • 0029155390 scopus 로고
    • Adenovirus types 2, 8, and 37 associated with genital infections in patients attending a sexually transmitted disease clinic
    • Swenson P. D., Lowens M. S., Celum C. L., Hierholzer J. C. Adenovirus types 2, 8, and 37 associated with genital infections in patients attending a sexually transmitted disease clinic. J. Clin. Microbiol. 33:1995;2728-2731.
    • (1995) J. Clin. Microbiol. , vol.33 , pp. 2728-2731
    • Swenson, P.D.1    Lowens, M.S.2    Celum, C.L.3    Hierholzer, J.C.4
  • 56
    • 0026654483 scopus 로고
    • Antipeptide antisera define neutralizing epitopes on the adenovirus hexon
    • Toogood C. I., Crompton J., Hay R. T. Antipeptide antisera define neutralizing epitopes on the adenovirus hexon. J. Gen. Virol. 73:1992;1429-1435.
    • (1992) J. Gen. Virol. , vol.73 , pp. 1429-1435
    • Toogood, C.I.1    Crompton, J.2    Hay, R.T.3
  • 57
    • 84913050729 scopus 로고
    • An efficient general-purpose least-squares refinement program for macromolecular structures
    • Tronrud D. E., Eyck L. T., Matthews B. W. An efficient general-purpose least-squares refinement program for macromolecular structures. Acta Crystallogr. A43:1987;489-501.
    • (1987) Acta Crystallogr. , vol.43 , pp. 489-501
    • Tronrud, D.E.1    Eyck, L.T.2    Matthews, B.W.3
  • 58
    • 0022348579 scopus 로고
    • Molecular composition of the adenovirus type 2 virion
    • van Oostrum J., Burnett R. M. Molecular composition of the adenovirus type 2 virion. J. Virol. 56:1985;439-448.
    • (1985) J. Virol. , vol.56 , pp. 439-448
    • Van Oostrum, J.1    Burnett, R.M.2
  • 59
    • 0025025328 scopus 로고
    • Antibodies with specificities against a dispase-produced 15-kilodalton hexon fragment neutralize adenovirus type 2 infectivity
    • Varga M. J., Bergman T., Everitt E. Antibodies with specificities against a dispase-produced 15-kilodalton hexon fragment neutralize adenovirus type 2 infectivity. J. Virol. 64:1990;4217-4225.
    • (1990) J. Virol. , vol.64 , pp. 4217-4225
    • Varga, M.J.1    Bergman, T.2    Everitt, E.3
  • 60
    • 0033061221 scopus 로고    scopus 로고
    • RGD inclusion in the hexon monomer provides adenovirus type 5-based vectors with a fiber knob-independent pathway for infection
    • Vigne E., Mahfouz I., Dedieu J.-F., Brie A., Perricaudet M., Yeh P. RGD inclusion in the hexon monomer provides adenovirus type 5-based vectors with a fiber knob-independent pathway for infection. J. Virol. 73:1999;5156-5161.
    • (1999) J. Virol. , vol.73 , pp. 5156-5161
    • Vigne, E.1    Mahfouz, I.2    Dedieu, J.-F.3    Brie, A.4    Perricaudet, M.5    Yeh, P.6
  • 62
    • 0023908115 scopus 로고
    • Neutralization of adenoviruses: Kinetics, stoichiometry, and mechanisms
    • Wohlfart C. Neutralization of adenoviruses: Kinetics, stoichiometry, and mechanisms. J. Virol. 62:1988;2321-2328.
    • (1988) J. Virol. , vol.62 , pp. 2321-2328
    • Wohlfart, C.1
  • 63
    • 0028937785 scopus 로고
    • Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
    • Yang Y., Li Q., Ertl H. C. J., Wilson J. M. Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses. J. Virol. 69:1995;2004-2015.
    • (1995) J. Virol. , vol.69 , pp. 2004-2015
    • Yang, Y.1    Li, Q.2    Ertl, H.C.J.3    Wilson, J.M.4
  • 64
    • 0028429545 scopus 로고
    • Adenovirus-mediated gene transfer for cystic fibrosis: Quantitative evaluation of repeated in vivo vector administration to the lung
    • Yei S., Mittereder N., Tang K., O'Sullivan C., Trapnell B. C. Adenovirus-mediated gene transfer for cystic fibrosis: Quantitative evaluation of repeated in vivo vector administration to the lung. Gene Ther. 1:1994;192-200.
    • (1994) Gene Ther. , vol.1 , pp. 192-200
    • Yei, S.1    Mittereder, N.2    Tang, K.3    O'Sullivan, C.4    Trapnell, B.C.5


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