In vivo adenoviral transduction of the neonatal rat cochlea and middle ear

Hearing Research

Volumn 151, Issue 1-2, 2001, Pages 30-40

  Dazert, Stefan ^a   Aletsee, Christoph ^a,b   Brors, Dominik ^a   Gravel, Claude ^c   Sendtner, Michael ^a   Ryan, Allen ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CENTRE DE RECHERCHE DE L INSTITUT UNIVERSITAIRE EN SANTÉ MENTALE DE QUÉBEC   (Canada)

Author keywords

Adenovirus vector; Cochlea; Gene transfer; Middle ear; Neonatal rat

Indexed keywords

BETA GALACTOSIDASE;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL INFILTRATION; CLONING VECTOR; COCHLEA; CONGENITAL DISORDER; CONTROLLED STUDY; CORTI ORGAN; EARDRUM; EPITHELIUM CELL; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSDUCTION; HAIR CELL; INFLAMMATION; INNER EAR; LEUKOCYTE; MESENCHYME; MIDDLE EAR; MUCOSA CELL; NEWBORN; NONHUMAN; PERILYMPH; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPORTER GENE; SPIRAL GANGLION; STROMA; TIME; TISSUE DISTRIBUTION; VESTIBULAR SYSTEM; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALS; ANIMALS, NEWBORN; BETA-GALACTOSIDASE; COCHLEA; EAR, MIDDLE; GENE EXPRESSION; GENES, REPORTER; GENETIC VECTORS; HUMANS; MUCOUS MEMBRANE; RATS; RATS, SPRAGUE-DAWLEY; TRANSDUCTION, GENETIC;

EID: 0034747743     PISSN: 03785955     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5955(00)00189-1     Document Type: Article

References (31)

1. Effects of cyclophosphamide on the pathogenesis of cytomegalovirus-induced labyrinthitis
2. Transfection of neonatal rat cochlear cells in vitro with an adenovirus vector
3. Focal delivery of fibroblast growth factor-1 by transfected cells induces spiral ganglion neurite targeting in vitro
4. General anesthesia in new born rodents for experimental microsurgery of the ear
5. Gene transfer into the mammalian inner ear using HSV-1 and vaccinia virus vectors
6. Gene delivery into the central nervous system by nasal instillation in rats
7. In vivo gene therapy with p53 or p21 adenovirus for prostate cancer
8. Defining responsiveness of avian cochlear neurons to brain-derived neurotrophic factor and nerve growth factor by HSV-1-mediated gene transfer
9. Adenoviral gene trasfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads to long-term survival of axotomized motor neurons
10. Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors (see comments)
11. Functional expression of exogenous proteins in mammalian sensory hair cells infected with adenoviral vectors
12. high efficiency gene transfer into the embryonic chicken CNS using B-subgroup retroviruses
13. Adenovirus-mediated gene therapy of hepatocellular carcinoma using cancer-specific gene expression
14. In vivo gene transfer into the embryonic inner ear using retroviral vectors
15. Development of in vivo gene therapy for hearing disorders: introduction of adeno-associated virus into the cochlea of the guinea pig
16. Basic fibroblast growth factor (FGF-2) protects rat cochlear hair cells in organotypical culture from aminoglycoside injury
17. Adenovirus-mediated in vivo gene transfer in guinea pig middle ear mucosa
18. Cellular events in tolerance. I. Induction and loss of tolerance in neonatal and adult rats
19. Adenoviral-mediated gene transfer into guinea pig cochlear cells in vivo
20. Adenovirus-mediated gene transfer to normal and atherosclerotic arteries. A novel approach
21. Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy
22. Transforming growth factor alpha treatment alters intracellular calcium levels in hair cells and protects them from ototoxic damage in vitro
23. Brain-derived neurotrophic factor gene therapy prevents spiral ganglion degeneration after hair cell loss
24. Transduction of the contralateral ear after adenovirus-mediated cochlear gene transfer
25. Transduction of LacZ gene into leukemia cells using viral vectors of retrovirus and adenovirus
26. FK506 immunosuppression to control the immune reactions triggered by first-generation adenovirus-mediated gene transfer
27. Cationic liposome mediated transgene expression in the guinea pig cochlea
28. Inner ear transgene expression after adenoviral vector inoculation in the endolymphatic sac
29. Adenoviral-mediated gene transfer into primary human and mouse mammary epithelial cells in vitro and in vivo
30. Establishment of conditionally immortalized rat utricular epithelial cell lines using a retrovirus-mediated gene transfer technique