Apolipoprotein E ε4 allele affects the relationship between stress and depression in caregivers of patients with Alzheimer's disease

Journal of Geriatric Psychiatry and Neurology

Volumn 14, Issue 3, 2001, Pages 115-119

  Gallagher Thompson, Dolores ^a,b   Ohara, Ruth ^a   Simmons, Alan ^b   Kraemer, Helena C ^a   Murphy, Greer M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E;

ADULT; AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; CAREGIVER; COGNITION; COMMUNITY CARE; DEPRESSION; FEMALE; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MENTAL STRESS; MOOD; PRIORITY JOURNAL; SELF REPORT; CROSS-SECTIONAL STUDY; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; MAJOR DEPRESSION; MALE; MEMORY DISORDER; MENTAL DISEASE; MIDDLE AGED; NEUROPSYCHOLOGICAL TEST; PSYCHOLOGICAL ASPECT;

ADULT; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; APOLIPOPROTEINS E; CAREGIVERS; CROSS-SECTIONAL STUDIES; DEPRESSIVE DISORDER, MAJOR; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MEMORY DISORDERS; MENTAL DISORDERS; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; STRESS, PSYCHOLOGICAL;

EID: 0034741621     PISSN: 08919887     EISSN: None     Source Type: Journal    
DOI: 10.1177/089198870101400303     Document Type: Article

References (54)

1. The effects of stress on memory and the hippocampus throughout the life cycle: Implications for childhood development and aging
2. Individual differences in hypothalamic-pituitary-adrenal activity in later life and hippocampal aging
3. Stress and the aging hippocampus
4. Hypothalamic-pituitary-adrenal axis regulation and human aging
5. Risk factors for Alzheimer's disease: The EURODEM collaborative re-analysis of case-control studies
6. The relationship of stressful life events to intellectual functioning in women over 65
7. Complexity of life-style and maintenance of intellectual abilities
8. Protective and damaging effects of stress mediators
9. The elders life stress inventory: Egocentric and nonegocentric stress
10. Development of an instrument to measure stress in the older adult
11. Stress and adaptational outcomes. The problem of confounded measures
12. Impact of psychoeducational interventions on distressed family care-givers
13. The role of social relations in health promotion
14. An analysis of coping in a middle-aged community sample
15. Health psychology: What is an unhealthy environment and how does it get under the skin?
16. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
17. The apo E epsilon 4 allele is associated with decline on delayed recall performance in community-dwelling older adults
18. Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E
19. Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease
20. Apolipoprotein E, dementia, and cortical deposition of beta-amyloid protein
21. Apolipoprotein E4 promotes incipient Alzheimer pathology in the elderly
22. Apolipoprotein E in nerve injury and repair
23. Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism
24. ApoE genotype and survival from intracerebral haemorrhage
25. Predictors of cognitive decline after cardiac operation
26. Apolipoprotein E epsilon 4 associated with chronic traumatic brain injury in boxing
27. ApoE as a prognostic factor for post-traumatic coma
28. Apolipoprotein E epsilon 4 allele is associated with deposition of amyloid beta-protein following head injury
29. Apolipoprotein-E deficiency results in an altered stress responsiveness in addition to an impaired spatial memory in young mice
30. Derangement in stress response of apolipoprotein E-deficient mice
31. Increased 3-nitrotyrosine in brains of Apo E-deficient mice
32. Apolipoprotein E deficiency worsens outcome from global cerebral ischemia in the mouse
33. Dominant negative effects of apolipoprotein E4 revealed in transgenic models of neurodegenerative disease
34. Psychiatric and physical morbidity effects of dementia caregiving: Prevalence, correlates, and causes
35. Primary stressors and depressive symptoms in caregivers of dementia patients
36. "Mini-Mental State". A practical method for grading the cognitive state of patients for the clinician
37. Assessment of behavioral problems in dementia: The revised memory and behavior problems checklist
38. Computerized tests of attention, memory and motor performance applied to geriatric research
39. The Geriatric Depression Scale: A comprehensive review
40. Geriatric Depression Scale (GDS): Recent evidence and development of a shorter version
41. The Geriatric Depression Scale: Its development and recent application
42. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with Hhal
43. No association between apolipoprotein E epsilon 4 allele and rate of decline in Alzheimer's disease
44. The National Institute on Aging/Alzheimer's Association recommendations on the application of apolipoprotein E genotyping to Alzheimer's disease
45. Diagnosis and treatment of depression in patients with Alzheimer's disease and other dementias
46. Depression in patients with Parkinson's disease
47. Treatment issues in poststroke depression
48. Apolipoprotein E-epsilon 4 allele frequency in late-onset depression
49. Association of the APOE epsilon 4 allele with clinical subtypes of late life depression
50. Apolipoprotein E status and depression in a longitudinal investigation of community-dwelling older adults
51. Apolipoprotein E-epsilon 4 frequency in geriatric depression
52. The millennium of mind, brain, and behavior