Identification of syntaxin 1A as a novel binding protein for presenilin-1

Molecular Brain Research

Volumn 78, Issue 1-2, 2000, Pages 100-107

  Smith, Stephanie K F ^a   Anderson, Howard A ^b   Yu, Gang ^c   Robertson, Alan G S ^a   Allen, Shelley J ^a   Tyler, Sue J ^a   Naylor, Ruth L ^a   Mason, Grant ^a   Wilcock, Gordon W ^a   Roche, Paul A ^b   Fraser, Paul E ^c   Dawbarn, David ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Alzheimer's disease; Presenilin 1; Syntaxin; Thioredoxin

Indexed keywords

BINDING PROTEIN; GLUTATHIONE TRANSFERASE; PRESENILIN 1; SYNTAXIN; SYNTAXIN 1A; THIOREDOXIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; CIRCULAR DICHROISM; GENE MUTATION; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN EXPRESSION; RAT; SYNAPSE VESICLE;

ALZHEIMER DISEASE; ANTIGENS, SURFACE; CELL MEMBRANE; CLONING, MOLECULAR; GENE EXPRESSION; GLYCEROL; HUMANS; MEMBRANE PROTEINS; MOLECULAR WEIGHT; NERVE TISSUE PROTEINS; NEURONS; PRECIPITIN TESTS; PRESENILIN-1; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SUBCELLULAR FRACTIONS; SYNAPTIC VESICLES; SYNTAXIN 1; THIOREDOXIN; TWO-HYBRID SYSTEM TECHNIQUES;

BACTERIA (MICROORGANISMS);

EID: 0034737988     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(00)00079-6     Document Type: Article

References (25)

1. D. Beher, C. Elle, J. Underwood, J.B. Davis, R. Ward, E. Karran, C.L. Masters, K. Beyreuther, G. Multhaup, Proteolytic fragments of Alzheimer's disease-associated presenilin 1 are present in synaptic organelles and growth cone membranes of rat brain, J. Neurochem. 72 (1999) 1564-1573.
2. D. Blacker, R.E. Tanzi, The genetics of Alzheimer disease - current status and future prospects, Arch. Neur. 55 (1998) 294-296.
3. J.D. Buxbaum, E-K. Choi, Y. Luo, C. Lilliehook, A.C. Crowley, D.E. Merriam, W. Wasco, Calsenilin: A calcium binding protein that interacts with the Presenilins and regulates the levels of a Presenilin fragment, Nat. Med. 4 (1998) 1177-1181.
4. A. Capell, R. Saffrich, J-C. Olivo, L. Meyn, J. Walter, J. Grünberg, P. Mathews, R. Nixon, C. Dotti, C. Haass, Cellular expression and proteolytic processing of presenilin proteins is developmentally regulated during neuronal differentiation, J. Neurochem. 69 (1997) 2432-2440.
5. R.A. Conlon, A.G. Reaume, J. Rossant, Notch-1 is required for the co-ordinate segmentation of somites, Development 121 (1995) 1533-1545.
6. B. DeStrooper, P. Saftig, K. Craessaerts, H. Vanderstichele, G. Guhde, W. Annaert, K. VonFigura, F. VanLeuven, Deficiency of Presenilin-1 inhibits the normal cleavage of amyloid precursor protein, Nature 391 (1998) 387-390.
7. M. Hrabe de Angelis, J. McIntyre, A. Gossler, Maintenance of somite borders in mice requires the Delta homologue Dll1, Nature 386 (1997) 717-721.
8. E.R. LaVallie, E.A. Diblasio, S. Kovacic, K.L. Grant, PF. Schendel, J.M. McCoy, A thioredoxin gene fusion expression system that circumvents inclusion body formation in the E. coli cytoplasm, Biotechnology 11 (1993) 187-193.
9. G. Lévesque, G. Yu, M. Nishimura, D.-M. Zhang, L. Lévesque, H. Yu, D. Xu, Y. Liang, E. Rogaeva, M. Ikeda, M. Duthie, N. Murgolo, L. Wang, P. VanderVere, M.L. Bayne, C.D. Strader, J.M. Rommens, P.E. Fraser, P. St George-Hyslop, Presenilins interact with armadillo proteins including neural specific plakophilin related protein and β-catenin, J. Neurochem. 72 (1998) 999-1008.
10. L. Lévesque, W. Annaert, K. Craessaets, P. Mathews, M. Seeger, R.A. Nixon, F. Van Leuven, S. Gandy, D. Westaway, P. St George-Hyslop, B. DeStrooper, P.E. Fraser, Developmental expression of wild-type and mutant presenilin 1 in hippocampal neurons from transgenic mice: Evidence for novel species - specific properties of human presenilin-1, Mol. Med. 5 (1999) 542-554.
11. E. LevyLahad, W. Wasco, P. Poorkaj, D.M. Romano, J. Oshima, W.H. Pettingell, C.E. Yu, P.D. Jondro, S.D. Schmidt, K. Wang, A.C. Crowley, Y.H. Fu, S.Y. Guenette, D. Galas, E. Nemens, E.M. Wijsman, T.D. Bird, G.D. Schellenberg, R.E. Tanzi, Candidate gene for the chromosome-1 familial Alzheimer's disease locus, Science 269 (1995) 973-977.
12. E.I. Rogaev, R. Sherrington, E.A. Rogaeva, G. Lévesque, M. Ikeda, Y. Liang, H. Chi, C. Lin, K. Holman, T. Tsuda, L. Mar, S. Sorbi, B. Nacmias, S. Piacentini, L. Amaducci, I. Chumakov, D. Cohen, L. Lannfelt, P.E. Fraser, J.M. Rommens, P.H. St GeorgeHyslop, Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome-1 related to the Alzheimer's disease type-3 gene, Nature 376 (1995) 775-778.
13. J. Shen, R.T. Bronson, D.F. Chen, W.M. Xia, D.J. Selkoe, S. Tonegawa, Skeletal and CNS defects in Presenilin-1-deficient mice, Cell 89 (1997) 629-639.
14. Z.-H. Sheng, J. Rettig, M. Takahashi, W.A. Catterall, Identification of a syntaxin-binding site on N-type calcium channels, Neuron 13 (1994) 1303-1313.
15. R. Sherrington, E.I. Rogaev, Y. Liang, E.A. Rogaeva, G. Levesque, M. Ikeda, H. Chi, C. Lin, G. Li, K. Holman, T. Tsuda, L. Mar, J.F. Foncin, A.C. Bruni, M.P. Montesi, S. Sorbi, I. Rainero, L. Pinessi, L. Nee, I. Chumakov, D. Pollen, A. Brookes, P. Sanseau, R.J. Polinsky, W. Wasco, H.A.R. daSilva, J.L. Haines, M.A. Pericak-Vance, R.E. Tanzi, A.D. Roses, P.E. Fraser, J.M. Rommens, P.H. St. GeorgeHyslop, Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease, Nature 375 (1995) 754-760.
16. G. Strahl, A. Adachi, Nuclear access and action of notch in vivo, Cell 93 (1998) 649-660.
17. A. Takashima, M. Murayama, O. Murayama, T. Kohno, T. Honda, K. Yasutake et al., Presenilin 1 associates with glycogen synthase kinase-3 beta and its substrate tau, Proc. Natl. Acad. Sci. (USA) 95 (1998) 9637-9641.
18. R.E. Tanzi, D.M. Kovacs, T.-W. Kim, R.D. Moir, S.Y. Guenette, W. Wasco, The gene defects responsible for familial Alzheimer's disease, Neurobiol. Dis. 3 (1996) 159.
19. M.L. Vitale, E.P. Seward, J.M. Trifaro, Chromaffin cell cortical actin network dynamics control the size of the release-ready vesicle pool and the initial rate of exocytosis, Neuron 14 (1995) 353-363.
20. M.S. Wolfe, W.M. Xia, B.L. Ostaszewski, T.S. Diehl, W.T. Kimberly, D.J. Selkoe, Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity, Nature 398 (1999) 513-517.
21. P.C. Wong, H. Zheng, H. Chen, M.W. Becher, D.J.S. Sirinathsinghji, M.E. Trumbauer, H.Y. Chen, D.L. Price, L.H.T. VanderPloeg, S.S. Sisodia, Presenilin 1 is required for Notch1 and Dll1 expression in the paraxial mesoderm, Nature 387 (1997) 288-292.
22. Y.H. Ye, N. Lukinova, M.E. Fortini, Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants, Nature 398 (1999) 525-529.
23. G. Yu, F. Chen, G. Levesque, M. Nishimura, D.-M. Zhang, L. Levesque, E. Rogaeva, D. Xu, Y. Liang, M. Duthie, P.H. St. George-Hyslop, P.E. Fraser, The Presenilin 1 protein is a component of a high molecular weight intracellular complex that contains β-catenin, J. Biol. Chem. 273 (1998) 16470-16475.
24. W.J. Zhang, S.W. Han, D.W. McKeel, A. Goate, J.Y. Wu, Interaction of presenilins with the filamin family of actin-binding proteins, J. Neurosci. 18 (1998) 914-922.
25. J.H. Zhou, U. Liyanage, M. Medina, C. Ho, A.D. Simmons, M. Lovett, K.S. Kosik, Presenilin 1 interaction in the brain with a novel member of the armadillo family, Neuroreport 8 (1997) 2085-2090.