Identification and characterization of coding single-nucleotide polymorphisms within a human olfactory receptor gene cluster

Gene

Volumn 260, Issue 1-2, 2000, Pages 87-94

  Sharon, Dror ^a   Gilad, Yoav ^a   Glusman, Gustavo ^a   Khen, Miriam ^a   Lancet, Doron ^a   Kalush, Francis ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Evolution; Genome diversity; Linkage disequilibrium; Olfaction

Indexed keywords

G PROTEIN COUPLED RECEPTOR; NUCLEOTIDE;

ARTICLE; CENTROMERE; CHROMOSOME 17P; EVOLUTION; GENE CLUSTER; GENE LINKAGE DISEQUILIBRIUM; GENETIC RECOMBINATION; GENOTYPE; HUMAN; OLFACTORY RECEPTOR; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; AMINO ACID SUBSTITUTION; DNA; GENE FREQUENCY; HUMANS; MULTIGENE FAMILY; POINT MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, ODORANT; SEQUENCE ANALYSIS, DNA; VARIATION (GENETICS);

EID: 0034736579     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(00)00467-4     Document Type: Article

References (38)

1. Specific anosmia and the concept of primary odors
2. Structure and function of receptors coupled to G proteins
3. Linkage disequilibrium relationships among four polymorphisms within the human fibrinogen gene cluster
4. Olfactory receptor gene cluster on human chromosome 17: Possible duplication of an ancestral receptor repertoire
5. A novel multigene family may encode odorant receptors: A molecular basis for odor recognition
6. Organization and evolution of olfactory receptor genes on human chromosome 11
7. Characterization of single-nucleotide polymorphisms in coding regions of human genes
8. Location of mouse and human genes corresponding to conserved canine olfactory receptor gene subfamilies
9. Population genetics - Making sense out of sequence
10. Variations on a theme: Cataloging human DNA sequence variation
11. Dichotomy of single-nucleotide polymorphism haplotypes in olfactory receptor genes and pseudogenes
12. Evidence for gene conversion in the generation of extensive polymorphism in the promoter of the growth hormone gene
13. Sequence analysis in the olfactory receptor gene cluster on human chromosome 17: Recombinatorial events affecting receptor diversity
14. Genome dynamics, polymorphisms and mutations in a 350 kb human olfactory receptor gene cluster
15. Sequence, structure, and evolution of a complete human olfactory receptor gene cluster
16. The olfactory receptor gene superfactory: Gene mining classification and nomenclature
17. Evidence for genetic determination in human twins of olfactory thresholds for a standard odorant
18. Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis
19. Evidence for balancing selection at HLA
20. Linkage disequilibrium as a gene-mapping tool
21. The use of a genetic map of biallelic markers in linkage studies
22. Comparative analysis of human DNA variations by fluorescence-based sequencing of PCR products
23. Olfactory receptors
24. Probability model for molecular recognition in biological receptor repertoires: Significance to the olfactory system
25. Low nucleotide diversity in man
26. Restriction endonuclease fingerprinting (REF): A sensitive method for screening mutations in long, contiguous segments of DNA
27. Analysis of complex genetic systems by ARMS-SSCP: Application to HLA genotyping
28. DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene
29. The variable and conserved interfaces of modeled olfactory receptor proteins
30. A molecular dissection of spatial patterning in the olfactory system
31. Distribution of olfactory receptor genes in the human genome
32. DnaSP version 2.0: A novel software package for extensive molecular population genetics analysis
33. Molecular phylogeny of the hominoids: Inferences from multiple independent DNA sequence data sets
34. Primate evolution of an olfactory receptor cluster: Diversification by gene conversion and recent emergence of pseudogenes
35. Members of the olfactory receptor gene family are contained in large blocks of DNA duplicated polymorphically near the ends of human chromosomes
36. Large-scale identification, mapping, and genotyping of single- nucleotide polymorphisms in the human genome
37. Ability to smell androstenone is genetically determined