Effects of in utero ethanol exposure and maternal treatment with a 5-HT(1A) agonist on S100B-containing glial cells

Developmental Brain Research

Volumn 121, Issue 2, 2000, Pages 133-143

  Eriksen, Jason L ^a   Gillespie, Roberta A ^a   Druse, Mary J ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

5 HT(1A) agonist; Astrocyte; Buspirone; Ethanol; Ipsapirone; Midline raphe glial structure; S100B

Indexed keywords

ALCOHOL; BUSPIRONE; IPSAPIRONE; NEUROTROPHIC FACTOR; PROTEIN S 100; PROTEIN S100B; SEROTONIN 1A AGONIST; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DORSAL RAPHE NUCLEUS; DRUG MECHANISM; FEMALE; FETUS; GLIA CELL; HYPOTHESIS; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; MATERNAL TREATMENT; MEDIAN RAPHE NUCLEUS; NONHUMAN; PRENATAL EXPOSURE; PRIORITY JOURNAL; RAPHE NUCLEUS; RAT; SEROTONINERGIC NERVE CELL;

ANIMALS; BUSPIRONE; CALCIUM-BINDING PROTEINS; CELL COUNT; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ETHANOL; FEMALE; FETAL ALCOHOL SYNDROME; GENE EXPRESSION; IN SITU HYBRIDIZATION; NERVE GROWTH FACTORS; NEUROGLIA; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PYRIMIDINES; RAPHE NUCLEI; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; RNA, MESSENGER; S100 PROTEINS; SEROTONIN AGONISTS;

EID: 0034733891     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-3806(00)00029-8     Document Type: Article

References (65)

1. Akbari H.M., Kramer H.K., Whitaker-Azmitia P.M., Spear L.P., Azmitia E.C. Prenatal cocaine exposure disrupts the development of the serotonergic system. Brain Res. 572:1992;57-63.
2. 1A receptor agonist. Neurosci. Lett. 170:1994;141-144.
3. Altman J., Bayer S.A. Atlas of Prenatal Brain Development. 1995;CRC Press, Boca Raton, FL.
4. B but not NGF, EGF, insulin or calmodulin is a CNS serotonergic growth factor. Brain Res. 516:1990;354-356.
5. Azmitia E.C., Rubinstein V.J., Strafaci J.A., Rios J.C., Whitaker-Azmitia P.M. 5-HT1A agonist and dexamethasone reversal of para-chloroamphetamine induced loss of MAP-2 and synaptophysin immunoreactivity in adult rat brain. Brain Res. 677:1995;181-192.
6. 1A receptor in primate brain neurons and glial cells. Neuropsychopharmacology. 14:1996;35-46.
7. Bhave S.V., Hoffman P.L. Ethanol promotes apoptosis in cerebellar granule cells by inhibiting the trophic effect of NMDA. J. Neurochem. 68:1997;578-586.
8. Cartwright M.M., Smith S.M. Increased cell death and reduced neural crest cell numbers in ethanol-exposed embryos: partial basis for the fetal alcohol syndrome phenotype. Alcohol. Clin. Exp. Res. 19:1995;378-386.
9. DeVitry F., Hamon M., Catelon J., Bubois M., Thibault J. Serotonin initiates and autoamplifies its own synthesis during mouse central nervous system development. Proc. Natl. Acad. Sci. USA. 83:1986;8629-8633.
10. Didier-Bazes M., Voutsinos B., Aguera M., Peyron C., Akaoka H., Belin M.F. Specific potentialities of embryonic rat serotonergic neurons to innervate different periventricular targets in the adult brain. J. Comp. Neurol. 382:1997;29-45.
11. Dinopoulos A., Dori I. The development of the serotonergic fiber network of the lateral ventricles of the rat brain: a light and electron microscopic immunocytochemical analysis. Exp. Neurol. 133:1995;73-84.
12. Druse M.J. Neurotransmitter function: changes associated with in utero alcohol exposure. Abel E.L. Fetal Alcohol Syndrome. From Mechanisms to Prevention. 1996;171-189 CRC Press, Boca Raton, FL.
13. Druse J.M., Paul L.H. Effects of in utero ethanol on serotonin uptake in cortical regions of offspring. Alcohol. 5:1989;455-459.
14. Druse M.J., Kuo A., Tajuddin N. Effects of in utero ethanol exposure on the developing serotonergic system. Alcohol. Clin. Exp. Res. 15:1991;678-684.
15. Druse M.J., Tajuddin N., Orrico L.A. In utero ethanol exposure reduces vimentin immunopositive astrocytes in neonatal rats. Soc. Neuroscience Abs. 25:1999;2021.
16. Druse M.J., Hao J.-L., Eriksen J.L. In utero ethanol exposure increases proenkephalin, a precursor of a neuropeptide that is inhibitory to neuronal growth. Alcohol. Clin. Exp. Res. 23:1999;1519-1527.
17. Dunn R., Landry C., O'Hanlon D., Dunn J J., Allore R., Brow I., Marks A. Reduction in S100 protein β subunit mRNA in C6 rat glioma cells following treatment with anti-microtubular drugs. J. Biol. Chem. 262:1987;3562-3566.
18. Guerri C., Renau-Piqueras J. Alcohol, astroglia, and brain development. Mol. Neurobiol. 15:1997;65-81.
19. Guerri C., Saez R., Sancho-Tello M., Martin de Aquilera E., Renau-Piqueras J. Ethanol alters astrocyte development: a study of critical periods using primary cultures. Neurochem. Res. 15:1990;559-565.
20. Guerri C., Saez R., Portoles M., Renau-Piqueras J. Derangement of astrogliogenesis as a possible mechanism involved in alcohol-induced alterations of central nervous system development. Alcohol Alcohol. Suppl. 2:1993;203-208.
21. Guizetti M., Catlin M., Costa L.G. The effects of ethanol on glial cell proliferation: relevance to the fetal alcohol syndrome. Front. Biosci. 2:1997;E93-E98.
22. 3H]8-Hydroxy-2-(di-n-propylamino)tetralin binding to pre- and postsynaptic 5-hydroxytryptamine sites in various regions of the brain. J. Neurochem. 44:1985;1685-1696.
23. Haring J.H., Hagan A., Olson J., Rodgers B. Hippocampal serotonin levels influence the expression of S100B detected by immunocytochemistry. Brain Res. 631:1993;119-123.
24. Haydon P.G., McCobb D.P., Kater S.B. Serotonin selectively inhibits growth cone motility and synaptogenesis of specific identified neurons. Science. 236:1984;561-564.
25. Haydon P.G., McCobb D.P., Kater S.B. The regulation of neurite outgrowth, growth cone motility and electrical synaptogenesis by serotonin. J. Neurobiol. 18:1987;197-215.
26. Holownia A., Ledig M., Menez J.F. Ethanol-induced cell death in cultured rat astroglia. Neurotox. Teratol. 19:1997;141-146.
27. Kennedy L.A., Mukerji S. Ethanol neurotoxicity. 1. Direct effect on replicating astrocytes. Neurobehav. Toxicol. Teratol. 8:1986;11-15.
28. Kim J.-A., Druse M.J. Protective effects of maternal buspirone treatment on serotonin reuptake sites in ethanol-exposed offspring. Dev. Brain Res. 92:1996;190-198.
29. Kim J.-A., Druse M.J. Deficiency of essential neurotrophic factors in conditioned media produced by ethanol-exposed cortical astrocytes. Dev. Brain Res. 96:1996;1-10.
30. 2 receptors in offspring. Alcohol. Clin. Exp. Res. 21:1997;1169-1178.
31. Kligman D., Marshak D.R. Purification and characterization of neurite extension factor from bovine brain. Proc. Natl Acad. Sci. USA. 83:1985;7136-7139.
32. Landry C.F., Ivy G.O., Dunn R.J., Marks A., Brown I.R. Expression of the gene encoding the β-subunit of S-100 protein in the developing rat brain analyzed by in situ hybridization. Mol. Brain Res. 6:1989;251-262.
33. Lauder J.M., Wallace J.A., Wilkie M.B., DiNome A., Krebs H. Roles for serotonin in neurogenesis. Monogr. Neural Sci. 9:1983;3-10.
34. Liesi P. Ethanol-exposed central neurons fail to migrate and undergo apoptosis. J. Neurosci. Res. 48:1997;439-448.
35. Liu J.P., Lauder J.M. S-100 and insulin-like growth factor-II differentially regulate growth of developing serotonin and dopamine neurons in vitro. J. Neurosci. Res. 33:1992;248-256.
36. Lokhorst D.K., Druse M.J. Effects of ethanol on cultured fetal astroglia. Alcohol. Clin. Exp. Res. 17:1993;810-815.
37. Lorez H.P., Richards J.G. 5-HT nerve terminals in the fourth ventricle of the rat brain: their identification and distribution studied by fluorescence histochemistry and electron microscopy. Cell Tissue Res. 165:1975;37-48.
38. Lorez H.P., Richards J.G. Supra-ependymal serotoninergic nerves in mammalian brain: morphological, pharmacological and functional studies. Brain Res. Bull. 9:1982;727-741.
39. Ludwin S.K., Kosek J.C., Eng L.F. The topographical distribution of S-100 and GFA proteins in the adult rat brain: an immunohistochemical study using horseradish peroxidase-labelled antibodies. J. Comp. Neurol. 165:1976;197-207.
40. McCobb D.P., Haydon P.G., Kater S.B. Dopamine and serotonin inhibition of neurite elongation of different identified neurons. J. Neurosci. Res. 19:1988;19-26.
41. Miller M.W., Potempa G. Numbers of neurons and glia in mature rat somatosensory cortex: effects of prenatal exposure to ethanol. J. Comp. Neurol. 29:1990;137-230.
42. Miller M.W., Robertson S. Prenatal exposure to ethanol alters the postnatal development and transformation of radial glia to astrocytes in the cortex. J. Comp. Neurol. 337:1993;253-266.
43. Paxinos G., Törk I., Tecott L.H., Valentino K.L. Atlas of the Developing Rat Brain. 1991;Academic Press, New York.
44. Rathbun W., Druse M.J. Dopamine, serotonin and acid metabolites in brain regions from the developing offspring of ethanol treated rats. J. Neurochem. 44:1985;57-62.
45. Sarnat H.B. Histochemistry and immunocytochemistry of the developing ependyma and choroid plexus. Microsc. Res. Tech. 41:1998;14-28.
46. Selinfreund R.H., Barger S.W., Pledger W.J., Van Eldik L.J. Neurotrophic protein S100 beta stimulates glial cell proliferation. Proc. Natl. Acad. Sci. USA. 88:1991;3554-3558.
47. Shetty A.K., Phillips D.E. Effects of prenatal ethanol exposure on the development of Bergmann glia and astrocytes in the rat cerebellum: an immunohistochemical study. J. Comp. Neurol. 321:1992;19-32.
48. Snyder A.K., Singh S.P., Ehmann S. Effects of ethanol on DNA, RNA, and protein synthesis in rat astrocyte cultures. Alcohol. Clin. Exp. Res. 16:1992;295-300.
49. Tajuddin N., Druse M.J. Treatment of pregnant alcohol-consuming rats with buspirone: effects on serotonin and 5-hydroxyindoleacetic acid content in offspring. Alcohol. Clin. Exp. Res. 17:1993;110-114.
50. Tajuddin N., Druse M.J. In utero ethanol exposure decreased the density of serotonin neurons. Maternal ipsapirone treatment exerted a protective effect. Dev. Brain Res. 117:1999;91-97.
51. Ueda S., Hou X.P., Whitaker-Azmitia P.M., Azmitia E.C. Neuro-glial neurotrophic interaction in the S-100 retarded mutant mouse (Polydactylyl Nagoya). II. Co-cultures study. Brain Res. 633:1994;284-288.
52. Ueda S., Kokotos Leonardi E.T., Bell J., Azmitia E.C. Serotonergic sprouting into transplanted C-6 gliomas is blocked by S-100 antisense gene. Mol. Brain Res. 29:1995;365-368.
53. Valles S., Sancho-Tello M., Mnana R., Climent E., Renau-Piqueras J., Guerri C. Glial fibrillary acidic protein expression in rat brain and in radial glia culture is delayed by prenatal ethanol exposure. J. Neurochem. 67:1996;2425-2433.
54. van Hartesveldt C., Moore B., Hartman B.K. Transient midline raphe glial structure in the developing rat. J. Comp. Neurol. 253:1986;175-184.
55. Voutsinos B., Chouaf I., Mertens P., Ruiz-Flandes P., Joubert Y., Belin M.F., Didier-Bazes M. Tropism of serotonergic neurons towards glial targets in the rat ependyma. Neuroscience. 59:1994;663-672.
56. West M.J., Slomianka L., Gundersen H.J. Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anat. Rec. 231:1991;482-497.
57. Whitaker-Azmitia P.M., Azmitia E.C. Autoregulation of fetal serotonergic neuronal development: role of high affinity serotonin receptors. Neurosci. Lett. 67:1986;307-312.
58. 1A receptors S-100 beta in development and plasticity. Perspect. Dev. Neurobiol. 2:1994;233-238.
59. 1A receptors releases the serotonergic growth factor, protein S-100, and alters astroglial morphology. Brain Res. 528:1990;155-158.
60. 1A receptors to astroglial cells in adult rats: implications for neuronal-glial interactions and psychoactive drug mechanism of action. Synapse. 14:1993;201-205.
61. Yang Q., Hamberger A., Wang S., Haglid K.G. Appearance of neuronal S-100β during development of rat brain. Dev. Brain Res. 91:1996;181-189.
62. Young W.S., Bonner T.I., Brann M.R. Mesencephalic dopamine neurons regulate the expression of neuropeptide mRNAs in the rat forebrain. Proc. Natl. Acad. Sci. USA. 83:1986;9827-9831.
63. Yukhanaov R.Y., Handa R.J. Effect of morphine on proenkephalin gene expression in the rat brain. Brain Res. Bull. 43:1997;349-356.
64. Zhang F.X., Rubin R., Rooney T.A. Ethanol induces apoptosis in cerebellar granule neurons by inhibiting insulin-life growth factor 1 signaling. J. Neurochem. 71:1998;196-204.
65. Zhou F.C., Goodlett C.R., Zhang J.K., Lumeng L., Li T.-K. Prenatal alcohol exposure affects serotonin-immunoreactive neurons in fetal C57BL/6J mice. Alcohol. Clin. Exp. Res. 22:1998;59A.