Protective effects of maternal buspirone treatment on serotonin reuptake sites in ethanol-exposed offspring

Developmental Brain Research

Volumn 92, Issue 2, 1996, Pages 190-198

  Kim, Jung Ae ^a   Druse, Mary J ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

5 HT(1A); Buspirone; Ethanol; Fetal alcohol syndrome; Reuptake; Serotonin

Indexed keywords

ALCOHOL; BUSPIRONE; CITALOPRAM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING SITE; BRAIN DEVELOPMENT; BRAIN REGION; CONTROLLED STUDY; EMBRYO; FETAL ALCOHOL SYNDROME; FETUS; NEWBORN; NONHUMAN; PRENATAL EXPOSURE; PRIORITY JOURNAL; RAT; SEROTONIN UPTAKE; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030007023     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-3806(96)00015-6     Document Type: Article

References (52)

1. Abel, E.L. and Sokol, R.J., A revised conservative estimate of the incidence of FAS and its economic impact, Alcohol. Clin. Exp. Res., 15 (1991) 514-524.
2. Akbari, J.M., Whitaker-Azmitia, P.M. and Azmitia, E.C., Prenatal cocaine decreases the trophic factor S-100 beta and induced microcephaly: reversal by postnatal 5-HT1A receptor agonist, Neurosci. Lett., 170 (1994) 141-144.
3. Andrade, R. and Nicoll, R.A., Novel anxiolytics discriminate between postsynaptic serotonin receptors mediating different physiological responses on single neurons of the rat hippocampus, Naunyn-Schmiedeberg's Arch. Pharmacol., 336 (1987) 5-10.
4. B but not NGF, EGF, insulin or calmodulin is a CNS serotonergic growth factor, Brain Res., 516 (1990) 354-356.
5. Barnes, D.E. and Walker, D.W., Prenatal ethanol exposure permanently reduces the number of pyramidal neurons in rat hippocampus, Dev. Brain Res., 1 (1981) 333-340.
6. Bonthius, D.J. and West, J.R., Alcohol-induced neuronal loss in developing rats: increased brain damage with binge exposure, Alcohol. Clin. Exp. Res., 14 (1990) 107-118.
7. Breese, C.R., D'Costa, A., Ingram, R.L., Lenham, J. and Sonntag, W.E., Long-term suppression of insulin-like growth factor-1 in rats after in utero ethanol exposure: relationship to somatic growth, J. Pharmacol. Exp. Ther., 264 (1993) 448-456.
8. Brodie, C., Kentroti, S. and Vernadakis, A., Growth factors attenuate the cholinotoxic effects of ethanol during early neuroembryogenesis in the chick embryo, Int. J. Dev. Neurosci., 9 (1991) 203-213.
9. Brodie, C. and Vernadakis, A., Ethanol increases cholinergic and decreases GABAergic neuronal expression in cultures derived from 8-day-old chick embryo cerebral hemispheres: interaction of ethanol and growth factors, Dev. Brain Res., 65 (1992) 253-257.
10. Budnik, V., Wu, C.F. and White, K., Altered branching of serotonin-containing neurons in Drosophila mutants unable to synthesize serotonin and dopamine, J. Neurosci., 9 (1989) 2866-2877.
11. Chubakov, A.R., Gromova, E.A., Konovalov, G.V., Sarkisova, E.F. and Chumasov, E.I., The effects of serotonin on the morpho-functional development of rat cerebral neocortex in tissue culture, Brain Res., 369 (1986) 285-297.
12. Cimino, M., Ponzio, F., Achilli, G., Vantini, G., Perego, C., Algeri, S., and Garrattini, S., Dopaminergic effects of buspirone, a novel anxiolytic agent, Biochem. Pharmacol., 32 (1983) 1069-1074.
13. Clarren, S.K., Alvord, E.C. Jr., Sumi, S.M., Streissguth, A.P. and Smith, D.W., Brain malformations related to prenatal exposure to ethanol, J. Pediatr., 92 (1978) 64-67.
14. Cowan, P.J., Anderson, I.M. and Grahame-Smith, D.G., Neuroendocrine effects of azapirones, J. Clin. Psychopharmacol., 10 (1990) 21S-25S.
15. 3H]imipramine, J. Pharmacol. Exp. Ther., 242 (1987) 364-371.
16. D'Amato, R.J., Blue, M.E., Largent, B.L., Lynch, D.R., Ledbetter, D.J., Molliver, M.E. and Snyder, S.H., Ontogeny of the serotonergic projection to rat neocortex: Transient expression of a dense innervation to primary sensory areas, Proc. Natl. Acad. Sci. USA, 84 (1987) 4322-4326.
17. DeVitry, F., Hamon, M., Catelon, J., Bubois, M. and Thibault, J., Serotonin initiates and autoamplifies its own synthesis during mouse central nervous system development, Proc. Natl. Acad. Sci. USA, 83 (1986) 8629-8633.
18. Done, C.J. and Sharpt, T., Biochemical evidence for the regulation of central noradrenergic activity by 5-HT1A receptors: microdialysis studies in the awake and anesthetized rat. Neuropharmacology, 33 (1994) 411-421.
19. Druse, M.J. and Paul, L.H., Effects of in utero ethanol exposure on serotonin uptake in cortical regions, Alcohol, 5 (1989) 455-459.
20. Druse, M.J., Kuo, A. and Tajuddin, N., Effects of in utero ethanol exposure on the developing serotonergic system, Alcohol. Clin. Exp. Res., 15 (1991) 678-684.
21. Druse, M.J., Effects of in utero ethanol exposure on the development of CNS neurotransmitter systems. In: M.W. Miller (Ed.), Development of the Central Nervous System. Effects of Alcohol and Opiates, Wiley-Liss, New York, 1992, pp. 139-167.
22. Druse, M.J., Effects of maternal alcohol consumption on the developing nervous system. In: R.R. Watson (Ed.), Alcohol and Neurobiology. Brain Development and Hormone Regulation, CRC Press, New York, 1992, pp. 1-30.
23. Feighner, J.P., Merideth, C.H. and G.A. Hendrickson, A double-blind comparison of buspirone and diazepam in outpatients with generalized anxiety disotder, J. Clin. Psychiatry, 43 (1982) 103-108.
24. Fletcher, P.J. and Davies, M., The involvement of 5-hydroxytryptaminergic and dopaminergic mechanisms in the eating induced by buspirone, gepirone and ipsapirone, Br. J. Pharmacol., 99 (1990) 519-525.
25. Haydon, P.G., McCobb, D.P. and Kater, S.B., Serotonin selectively inhibits growth cone motility and synaptogenesis of specific identified neurons, Science, 236 (1984) 561-564.
26. Haydon, P.G., McCobb, D.P. and Kater, S.B., The regulation of neurite outgrowth, growth cone motility, and electrical synaptogenesis by serotonin, J. Neurobiol., 18 (1987) 197-215.
27. Heaton, M.B., Swanson, D.J., Paiva, M. and Walker, D.W., Ethanol exposure affects trophic factor activity and responsiveness in chick embryo, Alcohol, 9 (1992) 161-166.
28. Heaton, M.B., Paiva, M., Swanson, D.J. and Walker, D.W., Responsiveness of cultured septal and hippocampal neurons to ethanol and neurotrophic substances, J. Neurosci. Res., 39 (1994) 305-318.
29. Lauder, J.M. and Krebs, H., Serotonin as a differentiation signal in early neurogenesis, Dev. Neurosci., 1 (1978) 15-30.
30. Lauder, J.M., Towle, A.C., Patrick, K., Henderson, P. and Krebs, H., Decreased serotonin content of embryonic raphe neurons following maternal administration of p-chlorophenylalanine: a quantitative immunocytochemical study, Dev. Brain Res., 20 (1985) 107-114.
31. Lauder, J.M., Ontogeny of the serotonergic system in the rat: serotonin as a developmental signal, Ann. NY Acad. Sci., 600 (1990) 297-313.
32. Miller, M.W. and Potempa, G., Numbers of neurons and glia in mature rat somatosensory cortex: Effects of prenatal exposure to ethanol, J. Comp. Neurol., 293 (1990) 92-102.
33. Noronha, A.B. and Druse, M.J., Maternal ethanol consumption and synaptic membrane glycoproteins in offspring, J. Neurosci. Res., 8 (1982) 83-97.
34. Paxinos, G. and Watson, C., The Rat Brain in Stereotaxic Coordinates, Academic Press, Sydney, 1986.
35. Pentney R.J. and Miller, M.W., Effects of ethanol on neuronal morphogenesis. In: M.W. Miller (Ed.), Development of the Central Nervous System. Effects of Alcohol and Opiates, Wiley-Liss, New York, 1992, pp. 71-108.
36. Pranzatelli, M.R. and Martens, J.M., Plasticity and ontogeny of the central 5-HT transporter: effect of neonatal 5, 7- dihydroxytryptamine lesions in the rat, Dev. Brain Res., 70 (1992) 191-195.
37. Rahman, H., Kentroti, S. and Vernadakis, A., The critical period for ethanol effects on cholinergic neuronal expression in neuroblast-enriched cultures derived from 3-day-old chick embryo: NGF ameliorates the cholinotoxic effects of ethanol, Int. J. Dev. Neurosci., 12 (1994) 397-404.
38. Rathbun, W. and Druse, M.J., Dopamine, serotonin and acid metabolites in brain regions from the developing offspring of ethanol treated rats, J. Neurochem., 44 (1985) 57-62.
39. Rimele, T.J., Henry, D.E., Lee, D.K.H., Geiger, G., Heaslip, R.J. and Grimes, D., Tissue-dependent alpha adrenoceptor activity of buspirone and related compounds, J. Pharmacol. Exp. Ther., 241 (1987) 771-778.
40. Sanger, D.J. and Shoemaker, H., Discriminative stimulus properties of 8-OH-DPAT: relationship to affinity to 5-HT1A receptors, Psychopharmacology, 108 (1992) 85-92.
41. Savage, D.D. and Swartzwelder, H.S., Effects of perinatal ethanol exposure on hippocampal formation. In: R.R. Watson (Ed.), Alcohol and Neurobiology. Brain Development and Hormone Regulation, CRC Press, New York, 1992, pp. 177-200.
42. Shemer, A., Whitaker-Azmitia, P.M. and Azmitia, E.C., Effects of prenatal 5-methoxytryptamine and parachlorophenylalanine on serotonergic uptake and behavior in the neonatal rat, Pharmacol. Biochem. Behav., 30 (1988) 547-851.
43. Shemer, A.V., Azmitia, E.C. and Whitaker-Azmitia, P.M. (1991) Dose-related effects of prenatal 5-methoxytryptamine (5-MT) on development of serotonin terminal density and behavior, Dev. Brain Res., 59 (1991) 59-63.
44. Singh, S.P., Srivenugopal, K.S., Ehmann, S., Yuan, X.-H. and Snyder, A.K., Insulin-like growth factors (IGF-I and IGF-II), IGF-binding proteins and IGF gene expression in the offspring of ethanol-fed rats, J. Lab. Clin. Med., 125 (1994) 183-192.
45. 1 receptors, Alcohol, 5 (1989) 465-470.
46. Tajuddin, N.F. and Druse, M.J., Treatment of pregnant alcohol-consuming rats with buspirone: effects of serotonin and 5-hydroxyindoleacetic acid content in offspring, Alcohol. Clin. Exp. Res., 17 (1993) 110-114.
47. Valles, S., Lindo, L., Montoliu, C., Renau-Piqueras, J. and Guerri, C., Prenatal exposure to ethanol induces changes in the nerve growth factor and its receptor in proliferating astrocytes in primary culture, Brain Res., 656 (1994) 281-286.
48. VanderMaelen, C.P., Matheson, G.K., Wilderman, R.C. and Patterson, L.A., Inhibition of serotonergic dorsal raphe neurons by systemic and iontophoretic administration of buspirone, a non-benzodiazepine anxiolytic drug, Eur. J. Pharmacol., 129 (1986) 123-130.
49. Volk, B., Delayed histogenesis in the 'embryofetal alcohol syndrome', Acta Neuropathol. (Berl.), 39 (1977) 157-163.
50. Whitaker-Azmitia, P.M. and Azmitia, E.C., Autoregulation of fetal serotonergic neuronal development: role of high affinity serotonin receptors, Neurosci. Lett., 67 (1986) 307-312.
51. Whitaker-Azmitia, P.M., Shemer, A.V., Caruso, J., Molino, L. and Azmitia, E.C., Role of high affinity serotonin receptors in neuronal growth, Ann. NY Acad. Sci., 600 (1990) 315-330.
52. 1A receptors S-100 beta in development and plasticity, Perspect. Dev. Neurobiol., 2 (1994) 2333-2338.