Single intracerebroventricular bolus injection of a recombinant adenovirus expressing leptin results in reduction of food intake and body weight in both lean and obese Zucker fa/fa rats

Regulatory Peptides

Volumn 92, Issue 1-3, 2000, Pages 57-64

  Muzzin, Patrick ^a   Cusin, Isabelle ^a   Charnay, Yves ^b   Rohner Jeanrenaud, Françoise ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b Division of Neuropsychiatry   (Switzerland)

Author keywords

Cerebrospinal fluid; Energy balance; Ependymal cells; Feeding behavior; Gene transfer; Obesity

Indexed keywords

COMPLEMENTARY DNA; LEPTIN; LEPTIN RECEPTOR;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BOLUS INJECTION; BRAIN VENTRICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; FEMALE; FOOD INTAKE; GENE TRANSFER; HYPERPHAGIA; HYPOTHALAMUS; LEAN BODY WEIGHT; MISSENSE MUTATION; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; PROTEIN EXPRESSION; RAT; SATIETY; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMAL; BODY WEIGHT; CEREBRAL VENTRICLES; COMPARATIVE STUDY; EATING; FEMALE; GENE EXPRESSION; GENETIC VECTORS; INJECTIONS, INTRAVENTRICULAR; LEPTIN; MICE; OBESITY; RATS; RATS, ZUCKER; RECOMBINANT FUSION PROTEINS; SUPPORT, NON-U.S. GOV'T;

EID: 0034714046     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-0115(00)00150-6     Document Type: Article

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