Regulation of p53 by metal ions and by antioxidants: Dithiocarbamate down-regulates p53 DNA-binding activity by increasing the intracellular level of copper

Molecular and Cellular Biology

Volumn 17, Issue 10, 1997, Pages 5699-5706

  Verhaegh, Gerald W ^a,b   Richard, Marie Jeanne ^c   Hainaut, Pierre ^b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^c HÔPITAL MICHALLON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; COPPER ION; DITHIOCARBAMIC ACID; METAL ION; PROTEIN P53;

ARTICLE; CELL STRAIN MCF 7; CONTROLLED STUDY; HUMAN; HUMAN CELL; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DNA BINDING; STRUCTURE ACTIVITY RELATION; TUMOR SUPPRESSOR GENE;

EID: 0030764172     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.10.5699     Document Type: Article

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