-
1
-
-
0025876591
-
The p53 tumour suppressor gene
-
Levine, A. J., Momand, J., and Finlay, C. A. The p53 tumour suppressor gene. Nature (Lond.), 357: 453-456, 1991.
-
(1991)
Nature (Lond.)
, vol.357
, pp. 453-456
-
-
Levine, A.J.1
Momand, J.2
Finlay, C.A.3
-
2
-
-
0030119061
-
The two faces of tumor suppressor p53
-
Smith. M. L., and Fornace, A. J., Jr. The two faces of tumor suppressor p53. Am. J. Pathol., 148: 1019-1022, 1996.
-
(1996)
Am. J. Pathol.
, vol.148
, pp. 1019-1022
-
-
Smith, M.L.1
Fornace Jr., A.J.2
-
3
-
-
0026801062
-
Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
-
Livingstone, L. R., White, A., Sprouse, J., Livanos, E., Jacks, T., and Tlsty, T. D. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell, 70: 923-935, 1992.
-
(1992)
Cell
, vol.70
, pp. 923-935
-
-
Livingstone, L.R.1
White, A.2
Sprouse, J.3
Livanos, E.4
Jacks, T.5
Tlsty, T.D.6
-
4
-
-
0028204160
-
DNA strand breaks: The DNA template alterations that trigger p53-dependent DNA damage response pathways
-
Nelson, W. G., and Kastan, M. B. DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways. Mol. Cell. Biol., 74: 1815-1823, 1994.
-
(1994)
Mol. Cell. Biol.
, vol.74
, pp. 1815-1823
-
-
Nelson, W.G.1
Kastan, M.B.2
-
5
-
-
0026496885
-
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
-
Kastan, M. B., Zhan, Q, El-Deiry, W. S., Carrier, F., Jacks, T., Walsh, W. V., Plunkett, B. S., Vogelstein, B., and Fornace, J., AJ. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell, 77: 587-597, 1992.
-
(1992)
Cell
, vol.77
, pp. 587-597
-
-
Kastan, M.B.1
Zhan, Q.2
El-Deiry, W.S.3
Carrier, F.4
Jacks, T.5
Walsh, W.V.6
Plunkett, B.S.7
Vogelstein, B.8
Fornace, J.9
J., A.10
-
6
-
-
0024436187
-
Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents
-
Fornace, A. J., Nebert, D. W., Hollander, M. C., Leuthy, J. D., Papathanasiou, M., Fargnoli, J., and Holbrook, N. J. Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents. Mol. Cell. Biol., 9: 4196-4203, 1989.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 4196-4203
-
-
Fornace, A.J.1
Nebert, D.W.2
Hollander, M.C.3
Leuthy, J.D.4
Papathanasiou, M.5
Fargnoli, J.6
Holbrook, N.J.7
-
7
-
-
0028175990
-
The p53-dependent γ-ray response of GADD45
-
Zhan, Q., Bae, I., Kastan, M. B., and Fornace, A. J., Jr. The p53-dependent γ-ray response of GADD45. Cancer Res., 54: 2755-2760, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 2755-2760
-
-
Zhan, Q.1
Bae, I.2
Kastan, M.B.3
Fornace Jr., A.J.4
-
8
-
-
0029858044
-
Mutations in the p53 and SCID genes cooperate in tumorigenesis
-
Nacht, M., Strasser, A., Chan, Y. R., Harris, A. W., Schlissel, M., Bronson, R. T., and Jacks, T. Mutations in the p53 and SCID genes cooperate in tumorigenesis. Genes Dev., 10: 2055-2066, 1996.
-
(1996)
Genes Dev.
, vol.10
, pp. 2055-2066
-
-
Nacht, M.1
Strasser, A.2
Chan, Y.R.3
Harris, A.W.4
Schlissel, M.5
Bronson, R.T.6
Jacks, T.7
-
9
-
-
0029858143
-
V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors
-
Guidos, C. J., Williams, C. J., Grandal, L, Knowles, G., Huang, M. T., and Danska, J. S. V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors. Genes Dev., 10: 2038-2054, 1996.
-
(1996)
Genes Dev.
, vol.10
, pp. 2038-2054
-
-
Guidos, C.J.1
Williams, C.J.2
Grandal, L.3
Knowles, G.4
Huang, M.T.5
Danska, J.S.6
-
10
-
-
0027298576
-
Induction of cellular p53 activity by DNA-damaging agents and growth arrest
-
Zhan, Q., Carrier, F., and Fornace, A. J., Jr. Induction of cellular p53 activity by DNA-damaging agents and growth arrest. Mol. Cell. Biol., 13: 4242-4250, 1993.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 4242-4250
-
-
Zhan, Q.1
Carrier, F.2
Fornace Jr., A.J.3
-
11
-
-
0028212767
-
Benzo(a)pyrene-7,8-diol-9,10-epoxide-DNA adducts and increased p53 protein in mouse skin
-
Lond.
-
Bjelogrlic, N. M., Makinen, M., Stenback, F., and Vahakangas, K. Benzo(a)pyrene-7,8-diol-9,10-epoxide-DNA adducts and increased p53 protein in mouse skin. Carcinogenesis (Lond.), 15: 771-774, 1994.
-
(1994)
Carcinogenesis
, vol.15
, pp. 771-774
-
-
Bjelogrlic, N.M.1
Makinen, M.2
Stenback, F.3
Vahakangas, K.4
-
12
-
-
0027500246
-
Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents
-
Fritsche, M., Haessler, C., and Brandner, G. Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents. Oncogene, 8: 307-318, 1993.
-
(1993)
Oncogene
, vol.8
, pp. 307-318
-
-
Fritsche, M.1
Haessler, C.2
Brandner, G.3
-
13
-
-
0021616838
-
UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells
-
Maltzman, W., and Czyzyk, L. UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells. Mol. Cell. Biol., 4: 1689-1694, 1984.
-
(1984)
Mol. Cell. Biol.
, vol.4
, pp. 1689-1694
-
-
Maltzman, W.1
Czyzyk, L.2
-
14
-
-
0021228029
-
Growth regulation of a cellular tumour antigen, p53, in nontransformed cells
-
Reich, N. C., and Levine, A. J. Growth regulation of a cellular tumour antigen, p53, in nontransformed cells. Nature (Lond.), 308: 199-201, 1984.
-
(1984)
Nature (Lond.)
, vol.308
, pp. 199-201
-
-
Reich, N.C.1
Levine, A.J.2
-
15
-
-
0025376482
-
Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2
-
Bischoff, J. R., Friedman, P. N., Marshak, D. R., Prives, C., and Beach, D. Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2. Proc. Natl. Acad. Sci. USA, 87: 4766-4770, 1990.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 4766-4770
-
-
Bischoff, J.R.1
Friedman, P.N.2
Marshak, D.R.3
Prives, C.4
Beach, D.5
-
16
-
-
0026316735
-
Guanine nucleotide biosynthesis is regulated by the cellular p53 concentration
-
Sherley, J. L. Guanine nucleotide biosynthesis is regulated by the cellular p53 concentration. J. Biol. Chem., 266: 24815-24828, 1991.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 24815-24828
-
-
Sherley, J.L.1
-
17
-
-
0029964158
-
1-, cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage
-
1-, cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage. Genes Dev., 10: 934-947, 1996.
-
(1996)
Genes Dev.
, vol.10
, pp. 934-947
-
-
Linke, S.P.1
Clarkin, K.C.2
Di Leonardo, A.3
Tsou, A.4
Wahl, G.M.5
-
18
-
-
0026093164
-
Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein
-
Martinez, J., Georgoff, I., Martinez, J., and Levine, A. J. Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein. Genes Dev., 5: 151-159, 1991.
-
(1991)
Genes Dev.
, vol.5
, pp. 151-159
-
-
Martinez, J.1
Georgoff, I.2
Martinez, J.3
Levine, A.J.4
-
19
-
-
0026046039
-
Nuclear localization is essential for the activity of p53 protein
-
Shaulsky, G., Goldfinger, N., Tosky, M. S, Levine, A. J., and Rotter, V. Nuclear localization is essential for the activity of p53 protein. Oncogene, 6: 2055-2065, 1991.
-
(1991)
Oncogene
, vol.6
, pp. 2055-2065
-
-
Shaulsky, G.1
Goldfinger, N.2
Tosky, M.S.3
Levine, A.J.4
Rotter, V.5
-
20
-
-
0026656853
-
Wild-type p53 is a cell cycle checkpoint determinant following irradiation
-
Kuerbitz, S. J., Plunkett, B. S., Walsh, W. V., and Kastan, M. B. Wild-type p53 is a cell cycle checkpoint determinant following irradiation, Proc. Natl. Acad. Sci. USA, 89: 7491-7495, 1992.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7491-7495
-
-
Kuerbitz, S.J.1
Plunkett, B.S.2
Walsh, W.V.3
Kastan, M.B.4
-
21
-
-
0026530821
-
Expression of p53 in human neuroblastoma- and neuroepithelioma-derived cell lines
-
Davidoff, A. M., Pence, J. C., Shorter, N. A., lglehart, J. D., and Marks, J. R. Expression of p53 in human neuroblastoma- and neuroepithelioma-derived cell lines. Oncogene, 7: 127-133, 1992.
-
(1992)
Oncogene
, vol.7
, pp. 127-133
-
-
Davidoff, A.M.1
Pence, J.C.2
Shorter, N.A.3
Lglehart, J.D.4
Marks, J.R.5
-
22
-
-
0026448672
-
Regulation of the specific DNA binding function of p53
-
Hupp, T. R., Meek, D. W., Midgley, C. A., and Lane, D. P. Regulation of the specific DNA binding function of p53. Cell, 71: 875-886, 1992.
-
(1992)
Cell
, vol.71
, pp. 875-886
-
-
Hupp, T.R.1
Meek, D.W.2
Midgley, C.A.3
Lane, D.P.4
-
23
-
-
0028221013
-
Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway
-
Chen, C. Y., Oliner, J. D., Zhan, Q., Fornace, A. J., Jr, Vogelstein, B., and Kastan, M. B. Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway. Proc. Natl. Acad. Sci. USA, 91: 2684-2688, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 2684-2688
-
-
Chen, C.Y.1
Oliner, J.D.2
Zhan, Q.3
Fornace Jr., A.J.4
Vogelstein, B.5
Kastan, M.B.6
-
24
-
-
0023793476
-
Radioprotection of cells in culture by WR-2721 and derivatives: Form of the drug responsible for protection
-
Smoluk, G. D., Fahey, R. C., Calabro-Jones, P. M., Aguilera, J. A., and Ward, J. F. Radioprotection of cells in culture by WR-2721 and derivatives: form of the drug responsible for protection. Cancer Res., 48: 3641-3647, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 3641-3647
-
-
Smoluk, G.D.1
Fahey, R.C.2
Calabro-Jones, P.M.3
Aguilera, J.A.4
Ward, J.F.5
-
25
-
-
0022259419
-
Mammalian cells are not killed by DNA single-strand breaks caused by hydroxyl radicals from hydrogen peroxide
-
Ward, J. F., Blakely, W. F., and Joner, E. I. Mammalian cells are not killed by DNA single-strand breaks caused by hydroxyl radicals from hydrogen peroxide. Radiât. Res., 103: 383-392, 1985.
-
(1985)
Radiât. Res.
, vol.103
, pp. 383-392
-
-
Ward, J.F.1
Blakely, W.F.2
Joner, E.I.3
-
26
-
-
0027537489
-
Doxorubicin-induced DNA breaks, topoisomerase II activity and gene expression in human melanoma cells
-
Ramachandran, C., Samy, T. S., Huang, X. L., Yuan, Z. K., and Krishan, A. Doxorubicin-induced DNA breaks, topoisomerase II activity and gene expression in human melanoma cells. Biochem. Pharmacol., 45: 1367-1371, 1993.
-
(1993)
Biochem. Pharmacol.
, vol.45
, pp. 1367-1371
-
-
Ramachandran, C.1
Samy, T.S.2
Huang, X.L.3
Yuan, Z.K.4
Krishan, A.5
-
27
-
-
78651117965
-
A molecular mechanism of mitomycin action: Linking of complementary DNA strands
-
Iyer, V. N., and Szybalski, W. A molecular mechanism of mitomycin action: linking of complementary DNA strands. Proc. Natl. Acad. Sci. USA, 50: 355-362, 1963.
-
(1963)
Proc. Natl. Acad. Sci. USA
, vol.50
, pp. 355-362
-
-
Iyer, V.N.1
Szybalski, W.2
-
28
-
-
0025360932
-
Recognition between mitomycin C and specific DNA sequences for cross-link formation
-
Borowy-Borowski, H., Lipman, R., and Tomasz, M. Recognition between mitomycin C and specific DNA sequences for cross-link formation. Biochemistry, 29: 2999-3006, 1990.
-
(1990)
Biochemistry
, vol.29
, pp. 2999-3006
-
-
Borowy-Borowski, H.1
Lipman, R.2
Tomasz, M.3
-
29
-
-
0025090818
-
Protection from cellular oxidative injury and calcium intrusion by N-(2-mercaptoethyl)-1,3-propanediamine, WR 1065
-
Polla, B. S., Donati, Y., Kondo, M., Tochon-Danguy, H. J., and Bonjour, J. P. Protection from cellular oxidative injury and calcium intrusion by N-(2-mercaptoethyl)-1,3-propanediamine, WR 1065. Biochem. Pharmacol., 40: 1469-1475, 1990.
-
(1990)
Biochem. Pharmacol.
, vol.40
, pp. 1469-1475
-
-
Polla, B.S.1
Donati, Y.2
Kondo, M.3
Tochon-Danguy, H.J.4
Bonjour, J.P.5
-
30
-
-
0021151237
-
Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II
-
Washington DC
-
Tewey, K. M., Rowe, T. C., Yang, L., Halligan, B. D., and Liu, L. F. Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II. Science (Washington DC), 226: 466-468, 1984.
-
(1984)
Science
, vol.226
, pp. 466-468
-
-
Tewey, K.M.1
Rowe, T.C.2
Yang, L.3
Halligan, B.D.4
Liu, L.F.5
-
31
-
-
0028071860
-
Differential intracellular processing of the anthracycline drug ME2303 in doxorubicin-sensitive (A2780) and -resistant (A2780AD) human ovarian cancer cells as studied with confocal laser scanning microscopy and image analysis
-
Huxham, I. M., Barlow, A. L., Lewis, A. D., Plumb, J., Mairs, R. J., Gaze, M. N., and Workman, P. Differential intracellular processing of the anthracycline drug ME2303 in doxorubicin-sensitive (A2780) and -resistant (A2780AD) human ovarian cancer cells as studied with confocal laser scanning microscopy and image analysis. Int. J. Cancer, 59: 94-102, 1994.
-
(1994)
Int. J. Cancer
, vol.59
, pp. 94-102
-
-
Huxham, I.M.1
Barlow, A.L.2
Lewis, A.D.3
Plumb, J.4
Mairs, R.J.5
Gaze, M.N.6
Workman, P.7
-
32
-
-
0024459570
-
Repair of DNA single- and double-strand breaks in proliferating and quiescent murine tumor cells
-
Sweigert, S. E., Eguchi-Kasai, K., Warters, R. L, and Dethlefsen, L. A. Repair of DNA single- and double-strand breaks in proliferating and quiescent murine tumor cells. Int. J. Radiat. Biol., 56: 253-264, 1989.
-
(1989)
Int. J. Radiat. Biol.
, vol.56
, pp. 253-264
-
-
Sweigert, S.E.1
Eguchi-Kasai, K.2
Warters, R.L.3
Dethlefsen, L.A.4
-
33
-
-
0027267939
-
Induction and repair of double-strand breaks in the replicating DNA of HeLa cells
-
Warters, R. L., and Lyons, B. W. Induction and repair of double-strand breaks in the replicating DNA of HeLa cells. Radiat. Res., 134: 337-342, 1993.
-
(1993)
Radiat. Res.
, vol.134
, pp. 337-342
-
-
Warters, R.L.1
Lyons, B.W.2
-
34
-
-
0021978722
-
On the nature of a defect in cells from individuals with ataxia-telangiectasia
-
Washington DC
-
Cornforth, M. N., and Bedford, J. S. On the nature of a defect in cells from individuals with ataxia-telangiectasia. Science (Washington DC), 227: 1589-1591, 1985.
-
(1985)
Science
, vol.227
, pp. 1589-1591
-
-
Cornforth, M.N.1
Bedford, J.S.2
-
35
-
-
0020418308
-
A comparison of the DNA and chromosome repair kinetics after irradiation
-
Hittleman, W. N., and Pollard, M. A comparison of the DNA and chromosome repair kinetics after irradiation. Radiat. Res., 92: 497-509, 1982.
-
(1982)
Radiat. Res.
, vol.92
, pp. 497-509
-
-
Hittleman, W.N.1
Pollard, M.2
-
36
-
-
0029049828
-
Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors
-
Moll, U. M., LaQuaglia, M., Benard, J., and Riou, G. Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors. Proc. Natl. Acad. Sci. USA, 92: 4407-4411, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4407-4411
-
-
Moll, U.M.1
LaQuaglia, M.2
Benard, J.3
Riou, G.4
-
37
-
-
0026694826
-
Two distinct mechanisms alter p53 in breast cancer: Mutation and nuclear exclusion
-
Moll, U. M., Riou, G., and Levine, A. J. Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion. Proc. Natl. Acad. Sci. USA, 89: 7262-7266, 1992.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7262-7266
-
-
Moll, U.M.1
Riou, G.2
Levine, A.J.3
-
38
-
-
0027221174
-
Mutant p53 proteins have diverse intracellular abilities to oligomerize and activate transcription
-
Miller, C. W., Chumakov, A., Said, J., Chen, D. L., Aslo, A., and Koeffler, H. P. Mutant p53 proteins have diverse intracellular abilities to oligomerize and activate transcription. Oncogene, 8: 1815-1824. 1993.
-
(1993)
Oncogene
, vol.8
, pp. 1815-1824
-
-
Miller, C.W.1
Chumakov, A.2
Said, J.3
Chen, D.L.4
Aslo, A.5
Koeffler, H.P.6
-
39
-
-
0028131554
-
Transcriptional activation by p53 correlates with suppression of growth but not transformation
-
Crook, T., Marston, N. J., Sara, E. A., and Vousden, K. H. Transcriptional activation by p53 correlates with suppression of growth but not transformation. Cell, 79: 817-827, 1994.
-
(1994)
Cell
, vol.79
, pp. 817-827
-
-
Crook, T.1
Marston, N.J.2
Sara, E.A.3
Vousden, K.H.4
-
40
-
-
0026054909
-
Growth suppression of human breast cancer cells by the introduction of a wild-type p53 gene
-
Casey, G., Lo-Hsueh, M., Lopez, M. E., Vogelstein, B., and Stanbridge, E. J. Growth suppression of human breast cancer cells by the introduction of a wild-type p53 gene. Oncogene, 6: 1791-1797, 1991.
-
(1991)
Oncogene
, vol.6
, pp. 1791-1797
-
-
Casey, G.1
Lo-Hsueh, M.2
Lopez, M.E.3
Vogelstein, B.4
Stanbridge, E.J.5
-
41
-
-
0019401161
-
Monoclonal antibodies specific for simian virus 40 tumor antigens
-
Harlow, E., Crawford, L V., Pim, D. C., and Williamson, N. M. Monoclonal antibodies specific for simian virus 40 tumor antigens. J. Virol., 39: 861-869, 1981.
-
(1981)
J. Virol.
, vol.39
, pp. 861-869
-
-
Harlow, E.1
Crawford, L.V.2
Pim, D.C.3
Williamson, N.M.4
-
42
-
-
0023394825
-
Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines
-
Hinds, P. W., Finlay, C. A., Frey, A. B., and Levine, A. J. Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines. Mol. Cell. Biol., 7: 2863-2869, 1987.
-
(1987)
Mol. Cell. Biol.
, vol.7
, pp. 2863-2869
-
-
Hinds, P.W.1
Finlay, C.A.2
Frey, A.B.3
Levine, A.J.4
|