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Volumn 219, Issue , 1999, Pages 76-96

Biological functions of connexin genes revealed by human genetic defects, dominant negative approaches and targeted deletions in the mouse

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 32; CONNEXIN 43; GAP JUNCTION PROTEIN;

EID: 0032605229     PISSN: None     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Article
Times cited : (42)

References (38)
  • 1
    • 0030979840 scopus 로고    scopus 로고
    • Structural abnormalities and deficient maintenance of peripheral nerve myelin in mice lacking the gap junctional protein connexin32
    • Anzini P, Neuberg DH, Schachner M et al 1997 Structural abnormalities and deficient maintenance of peripheral nerve myelin in mice lacking the gap junctional protein connexin32. J Neurosci 17:4545-4561
    • (1997) J Neurosci , vol.17 , pp. 4545-4561
    • Anzini, P.1    Neuberg, D.H.2    Schachner, M.3
  • 2
    • 0027772413 scopus 로고
    • Connexin mutations in X-linked Charcot-Marie-Tooth disease
    • Bergoffen J, Scherer SS, Wang S et al 1993 Connexin mutations in X-linked Charcot-Marie-Tooth disease. Science 262:2039-2042
    • (1993) Science , vol.262 , pp. 2039-2042
    • Bergoffen, J.1    Scherer, S.S.2    Wang, S.3
  • 3
    • 0029060788 scopus 로고
    • Mutations of the connexin43 gap-junction gene in patients with heart malformations and defects of laterality
    • Britz-Cunningham SH, Shah MM, Zuppan CW, Fletcher WH 1995 Mutations of the connexin43 gap-junction gene in patients with heart malformations and defects of laterality. N Engl J Med 332:1323-1329
    • (1995) N Engl J Med , vol.332 , pp. 1323-1329
    • Britz-Cunningham, S.H.1    Shah, M.M.2    Zuppan, C.W.3    Fletcher, W.H.4
  • 4
    • 0028018967 scopus 로고
    • Null mutations of connexin32 in patients with X-linked Charcot-Marie-Tooth disease
    • Bruzzone R, White TW, Scherer SS, Fischbeck KH, Paul DL 1994 Null mutations of connexin32 in patients with X-linked Charcot-Marie-Tooth disease. Neuron 13:1253-1260
    • (1994) Neuron , vol.13 , pp. 1253-1260
    • Bruzzone, R.1    White, T.W.2    Scherer, S.S.3    Fischbeck, K.H.4    Paul, D.L.5
  • 5
    • 0029986744 scopus 로고    scopus 로고
    • A role for an inhibitory connexin in testis?
    • Chang M, Werner R, Dahl G 1996 A role for an inhibitory connexin in testis? Dev Biol 175:50-56
    • (1996) Dev Biol , vol.175 , pp. 50-56
    • Chang, M.1    Werner, R.2    Dahl, G.3
  • 6
    • 0032101281 scopus 로고    scopus 로고
    • Enhanced secretion of amylase from exocrine pancreas in connexin32-deficient mice
    • Chanson M, Fanjul M, Bosco D et al 1998 Enhanced secretion of amylase from exocrine pancreas in connexin32-deficient mice. J Cell Biol 141:1267-1275
    • (1998) J Cell Biol , vol.141 , pp. 1267-1275
    • Chanson, M.1    Fanjul, M.2    Bosco, D.3
  • 7
    • 9844252338 scopus 로고    scopus 로고
    • Prelingual deafness: High prevalence of a 30delG mutation in the connexin26 gene
    • Denoyelle F, Weil D, Maw MA et al 1997 Prelingual deafness: high prevalence of a 30delG mutation in the connexin26 gene. Hum Mol Genet 6:2173-2177
    • (1997) Hum Mol Genet , vol.6 , pp. 2173-2177
    • Denoyelle, F.1    Weil, D.2    Maw, M.A.3
  • 8
    • 0040065086 scopus 로고    scopus 로고
    • Connexin32 and X-linked Charcot-Marie-Tooth disease
    • Spray DC, Dermietzel R (eds) Springer-Verlag, Heidelberg
    • Deschênes SM, Bone LJ, Fischbeck KH, Scherer SS 1996 Connexin32 and X-linked Charcot-Marie-Tooth disease. In: Spray DC, Dermietzel R (eds) Gap junctions in the nervous system. Springer-Verlag, Heidelberg, p 213-227
    • (1996) Gap Junctions in the Nervous System , pp. 213-227
    • Deschênes, S.M.1    Bone, L.J.2    Fischbeck, K.H.3    Scherer, S.S.4
  • 9
    • 0030809793 scopus 로고    scopus 로고
    • Dominant negative abrogation of connexin-mediated growth control by mutant connexin genes
    • Duflot-Dancer A, Mesnil M, Yamasaki H 1997 Dominant negative abrogation of connexin-mediated growth control by mutant connexin genes. Oncogene 15:2151-2158
    • (1997) Oncogene , vol.15 , pp. 2151-2158
    • Duflot-Dancer, A.1    Mesnil, M.2    Yamasaki, H.3
  • 10
    • 0032559798 scopus 로고    scopus 로고
    • Transplacental uptake of glucose is decreased in embryonic lethal connexin26 deficient mice
    • Gabriel H-D, Jung D, Bützler C et al 1998 Transplacental uptake of glucose is decreased in embryonic lethal connexin26 deficient mice. J Cell Biol 140:1453-1461
    • (1998) J Cell Biol , vol.140 , pp. 1453-1461
    • Gabriel, H.-D.1    Jung, D.2    Bützler, C.3
  • 11
    • 0029825134 scopus 로고    scopus 로고
    • Failure to detect connexin43 mutations in 38 cases of sporadic and familial heterotaxy
    • Gebbia M, Towbin J, Casey B 1996 Failure to detect connexin43 mutations in 38 cases of sporadic and familial heterotaxy. Circulation 94:1909-1912
    • (1996) Circulation , vol.94 , pp. 1909-1912
    • Gebbia, M.1    Towbin, J.2    Casey, B.3
  • 12
    • 0031283282 scopus 로고    scopus 로고
    • Disruption of α3 connexin gene leads to proteolysis and cataractogenesis in mice
    • Gong X, Li E, Kliev G et al 1997 Disruption of α3 connexin gene leads to proteolysis and cataractogenesis in mice. Cell 91:833-843
    • (1997) Cell , vol.91 , pp. 833-843
    • Gong, X.1    Li, E.2    Kliev, G.3
  • 14
    • 0030983063 scopus 로고    scopus 로고
    • Slow ventricular conduction in mice heterozygous for a connexin43 null mutation
    • Guerrero PA, Schuessler RB, Davies LM et al 1997 Slow ventricular conduction in mice heterozygous for a connexin43 null mutation. J Clin Invest 99:1991-1998
    • (1997) J Clin Invest , vol.99 , pp. 1991-1998
    • Guerrero, P.A.1    Schuessler, R.B.2    Davies, L.M.3
  • 15
    • 0345561557 scopus 로고    scopus 로고
    • Doubly mutant mice, deficient in connexin32 and 43, show normal prenatal development of organs where the two gap junction proteins are expressed in the same cells
    • in press
    • Houghton ED, Thönnissen E, Kidder GM et al 1999 Doubly mutant mice, deficient in connexin32 and 43, show normal prenatal development of organs where the two gap junction proteins are expressed in the same cells. Dev Gen, in press
    • (1999) Dev Gen
    • Houghton, E.D.1    Thönnissen, E.2    Kidder, G.M.3
  • 16
    • 0031007349 scopus 로고    scopus 로고
    • Connexin26 mutations in hereditary non-syndromic sensorineural deafness
    • Kelsell DP, Dunlop J, Stevens HP et al 1997 Connexin26 mutations in hereditary non-syndromic sensorineural deafness. Nature 387:80-83
    • (1997) Nature , vol.387 , pp. 80-83
    • Kelsell, D.P.1    Dunlop, J.2    Stevens, H.P.3
  • 17
    • 0028843286 scopus 로고
    • Gap junctions in rat cochlea: Immunochemical and ultrastructural analysis
    • Kikuchi T, Kimar R, Paul DL, Adams J 1995 Gap junctions in rat cochlea: immunochemical and ultrastructural analysis. Anat Embryol 91:101-118
    • (1995) Anat Embryol , vol.91 , pp. 101-118
    • Kikuchi, T.1    Kimar, R.2    Paul, D.L.3    Adams, J.4
  • 18
    • 0032567957 scopus 로고    scopus 로고
    • Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient mice
    • Kirchhoff S, Nelles E, Hagendorff A, Krüger O, Traub O, Willecke K 1998 Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient mice. Curr Biol 8:299-302
    • (1998) Curr Biol , vol.8 , pp. 299-302
    • Kirchhoff, S.1    Nelles, E.2    Hagendorff, A.3    Krüger, O.4    Traub, O.5    Willecke, K.6
  • 19
    • 0030028301 scopus 로고    scopus 로고
    • The gap junction communication channel
    • Kumar NM, Gilula NB 1996 The gap junction communication channel. Cell 84:381-388
    • (1996) Cell , vol.84 , pp. 381-388
    • Kumar, N.M.1    Gilula, N.B.2
  • 20
    • 0029742875 scopus 로고    scopus 로고
    • The role of gap junction membrane channels in development
    • Lo CW 1996 The role of gap junction membrane channels in development. J Bioenerg Biomembr 28:379-385
    • (1996) J Bioenerg Biomembr , vol.28 , pp. 379-385
    • Lo, C.W.1
  • 22
    • 0030696172 scopus 로고    scopus 로고
    • Animal models for inherited peripheral neuropathies
    • Martini R 1997 Animal models for inherited peripheral neuropathies. J Anat 191:321-336
    • (1997) J Anat , vol.191 , pp. 321-336
    • Martini, R.1
  • 23
    • 0023378034 scopus 로고
    • Junctional coupling modulates secretion of exocrine pancreas
    • Meda P, Bruzzone R, Bosco D, Orci L 1987 Junctional coupling modulates secretion of exocrine pancreas. Proc Natl Acad Sci USA 84:4901-4904
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 4901-4904
    • Meda, P.1    Bruzzone, R.2    Bosco, D.3    Orci, L.4
  • 24
    • 0343687249 scopus 로고    scopus 로고
    • Defective propagation of signals generated by sympathetic nerve stimulation in the liver of connexin32-deficient mice
    • Nelles E, Bützler C, Jung D et al 1996 Defective propagation of signals generated by sympathetic nerve stimulation in the liver of connexin32-deficient mice. Proc Natl Acad Sci USA 93:9565-9570
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9565-9570
    • Nelles, E.1    Bützler, C.2    Jung, D.3
  • 25
    • 0029977355 scopus 로고    scopus 로고
    • Connexin32 mutations from X-linked Charcot-Marie-Tooth disease patients: Functional defects and dominant negative effects
    • Omori Y, Mesnil M, Yamasaki H 1996 Connexin32 mutations from X-linked Charcot-Marie-Tooth disease patients: functional defects and dominant negative effects. Mol Biol Cell 7:907-916
    • (1996) Mol Biol Cell , vol.7 , pp. 907-916
    • Omori, Y.1    Mesnil, M.2    Yamasaki, H.3
  • 26
    • 0028231331 scopus 로고
    • Charcot-Marie-Tooth disease: A new paradigm for the mechanism of inherited disease
    • Patel IP, Lupski JR 1994 Charcot-Marie-Tooth disease: a new paradigm for the mechanism of inherited disease. Trends Genet 10:128-133
    • (1994) Trends Genet , vol.10 , pp. 128-133
    • Patel, I.P.1    Lupski, J.R.2
  • 27
    • 0004600209 scopus 로고    scopus 로고
    • Absence of mutations in the regulatory domain of the gap junction protein connexin43 in patients with visceroatrial heterotaxy
    • Penman-Splitt M, Tsai M, Burn J, Goodship JA 1997 Absence of mutations in the regulatory domain of the gap junction protein connexin43 in patients with visceroatrial heterotaxy. Heart 77:369-370
    • (1997) Heart , vol.77 , pp. 369-370
    • Penman-Splitt, M.1    Tsai, M.2    Burn, J.3    Goodship, J.A.4
  • 29
    • 0028907907 scopus 로고
    • Cardiac malformation in neonatal mice lacking connexin43
    • Reaume AG, de Sousa AP, Kulkarni S et al 1995 Cardiac malformation in neonatal mice lacking connexin43. Science 267:1831-1834
    • (1995) Science , vol.267 , pp. 1831-1834
    • Reaume, A.G.1    De Sousa, A.P.2    Kulkarni, S.3
  • 31
    • 0030018119 scopus 로고    scopus 로고
    • Immunolocalization of GLUT1 and connexin26 in the rat placenta
    • Shin BC, Suzuki T, Matsuzaki T et al 1996 Immunolocalization of GLUT1 and connexin26 in the rat placenta. Cell Tissue Res 285:83-89
    • (1996) Cell Tissue Res , vol.285 , pp. 83-89
    • Shin, B.C.1    Suzuki, T.2    Matsuzaki, T.3
  • 32
    • 0031016934 scopus 로고    scopus 로고
    • Female infertility in mice lacking connexin37
    • Simon AM, Goodenough DA, Li E, Paul DL 1997 Female infertility in mice lacking connexin37. Nature 385:525-529
    • (1997) Nature , vol.385 , pp. 525-529
    • Simon, A.M.1    Goodenough, D.A.2    Li, E.3    Paul, D.L.4
  • 33
    • 0032567887 scopus 로고    scopus 로고
    • Mice lacking connexin40 have cardiac conduction abnormalities characteristic of first-degree atriaventricular block and bundle branch block
    • Simon AM, Goodenough DA, Paul DL 1998 Mice lacking connexin40 have cardiac conduction abnormalities characteristic of first-degree atriaventricular block and bundle branch block. Curr Biol 8:295-298
    • (1998) Curr Biol , vol.8 , pp. 295-298
    • Simon, A.M.1    Goodenough, D.A.2    Paul, D.L.3
  • 34
    • 0031240077 scopus 로고    scopus 로고
    • High incidence of spontaneous and chemically induced liver tumors in mice deficient for connexin32
    • Temme A, Buchmann A, Gabriel H-D, Nelles E, Schwarz M, Willecke K 1997 High incidence of spontaneous and chemically induced liver tumors in mice deficient for connexin32. Curr Biol 7:713-716
    • (1997) Curr Biol , vol.7 , pp. 713-716
    • Temme, A.1    Buchmann, A.2    Gabriel, H.-D.3    Nelles, E.4    Schwarz, M.5    Willecke, K.6
  • 38
    • 9844245885 scopus 로고    scopus 로고
    • Connexin26 mutations associated with the most common form of non-syndromic neurosensory autosomal recessive deafness (DFNB1) in Mediterraneans
    • Zelante L, Gasparini P, Estivill X et al 1997 Connexin26 mutations associated with the most common form of non-syndromic neurosensory autosomal recessive deafness (DFNB1) in Mediterraneans. Hum Mol Genet 6:1605-1609
    • (1997) Hum Mol Genet , vol.6 , pp. 1605-1609
    • Zelante, L.1    Gasparini, P.2    Estivill, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.