KvLQT1, a voltage-gated potassium channel responsible for human cardiac arrhythmias

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 8, 1997, Pages 4017-4021

  Yang, Wen Pin ^a   Levesque, Paul C ^a   Little, Wayne A ^a   Conder, Mary Lee ^a   Shalaby, Fouad Y ^a   Blanar, Michael A ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; CLOFILIUM; CYCLIC AMP; DOFETILIDE; POTASSIUM CHANNEL; VOLTAGE GATED CHANNEL FORMING PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CHROMOSOME 11; ELECTROPHYSIOLOGY; GENE EXPRESSION; HEART ARRHYTHMIA; HUMAN; LONG QT SYNDROME; MOLECULAR CLONING; NONHUMAN; OOCYTE; OPEN READING FRAME; POTASSIUM CONDUCTANCE; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; TORSADE DES POINTES; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; GENE EXPRESSION; HEART; HUMANS; KCNQ POTASSIUM CHANNELS; KCNQ1 POTASSIUM CHANNEL; MOLECULAR SEQUENCE DATA; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; TACHYCARDIA, VENTRICULAR; XENOPUS;

ANIMALIA; MUSTELA VISON; XENOPUS LAEVIS;

EID: 0030890712     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.8.4017     Document Type: Article

References (26)

1. Wang, Q., Curran, M. E., Splawski, I., Burns, T. C., Millholland, J. M., VanRaay, T. J., Shen, J., Timothy, K. W., Vincent, G. M., Jager, T. D., Schwartz, P. J., Towbin, J. A., Moss, A. J., Atkinson, D. L., Landes, G. M., Conners, T. D. & Keating, M. T. (1996) Nat. Genet. 12, 17-23.
2. Curran, M. E., Splawski, I., Timothy, K. W., Vincent, G. M., Green, E. D. & Keating, M. T. (1995) Cell 80, 795-803.
3. Wang, Q., Shen, J., Splawski, I., Atkinson, D., Li, Z., Robinson, J. L., Moss, A. J., Towbin, J. A. & Keating, M. T. (1995) Cell 80, 805-811.
4. Roden, D. M., Lazzara, R., Rosen, M., Schwartz, P. J., Towbin, J. & Vincent, G. M. (1996) Circulation 94, 1996-2012.
5. Kass, R. S. & Davies, M. P. (1996) Cardiovasc. Res. 32, 443-454.
6. Sanguinetti, M. C., Jiang, C., Curran, M. E. & Keating, M. T. (1995) Cell 81, 299-307.
7. Sanguinetti, M. C., Curran, M. E., Spector, P. S. & Keating, M. T. (1996) Proc. Natl. Acad. Sci. USA 93, 2208-2212.
8. Bennett, P. B., Yazawa, K., Makita, N. & George, A. L., Jr. (1995) Nature (London) 376, 683-685.
9. Levesque, P. C., Hart, P. J., Hume, J. R., Kenyon, J. L. & Horowitz, B. (1992) Circ. Res. 71, 1002-1007.
10. Issa, J.-P. J. & Baylin, S. B. (1996) Nat. Med. 2, 281-282.
11. Honoré, E., Attali, B., Romey, G., Heurteaux, C., Ricard, P., Lesage, F., Lazdunski, M. & Barhanin, J. (1991) EMBO J. 10, 2805-2811.
12. Arena, J. P. & Kass, R. S. (1988) Mol. Pharmacol. 34, 60-66.
13. Colatsky, T. J., Follmer, C. H. & Starmer, C. F. (1990) Circulation 82, 2235-2242.
14. Sanguinetti, M. C. & Jurkiewicz, N. K. (1990) J. Gen. Physiol. 96, 195-215.
15. Wang, Z., Fermini, B. & Nattel, S. (1993) Circ. Res. 73, 1061-1076.
16. Jurkiewicz, N. K. & Sanguinetti, M. C. (1993) Circ. Res. 72, 75-83.
17. Blumenthal, E. M. & Kaczmarek, L. K. (1992) J. Neurosci. 12, 290-296.
18. Snyders, D. J. & Chaudhary, A. (1996) Mol. Pharmacol. 49, 949-955.
19. Balser, J. R., Bennett, P. B., Hondeghem, L. M. & Roden, D. M. (1991) Circ. Res. 69, 519-529.
20. Deal, K. K., England, S. K. & Tamkun, M. M. (1996) Physiol. Rev. 76, 49-67.
21. Folander, K., Smith, J. S., Antanavage, J., Bennett, C., Stein, R. B. & Swanson, R. (1990) Proc. Natl. Acad. Sci. USA 87, 2975-2979.
22. Varnum, M. D., Busch, A. E., Bond, C. T., Maylie, J. & Adelman, J. P. (1993) Proc. Natl. Acad. Sci. USA 90, 11528-11532.
23. Ben-Efraim, I., Shai, Y. & Attali, B. (1996) J. Biol. Chem. 271, 8768-8771.
24. Barhanin, J., Lesage, F., Guillemare, E., Fink, M., Lazdunski, M. & Romey, G. (1996) Nature (London) 384, 78-80.
25. Sanguinetti, M. C., Curran, M. E., Zou, A., Shen, J., Spector, P. S., Atkinson, D. L. & Keating, M. T. (1996) Nature (London) 384, 80-83.
26. Lee, M. P., Hu, R.-J., Johnson, L. A. & Fineberg, A. P. (1997) Nat. Genet. 15, 181-185.