Neurogenic vasodilation in rabbit basilar isolated artery: Involvement of calcitonin-gene related peptide

European Journal of Pharmacology

Volumn 395, Issue 1, 2000, Pages 61-68

  Olivar, Teresa ^a,b   Razzaque, Zerin ^a   Nwagwu, Margaret ^a   Longmore, Jenny ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

^b UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

CGRP (calcitonin gene related peptide); Migraine; Sensory nerve fibre; Vasodilation

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; CALCITONIN GENE RELATED PEPTIDE[8-37]; CAPSAICIN; PEPTIDE FRAGMENT; PROSTAGLANDIN F2 ALPHA; PROTEIN SUBUNIT; SEROTONIN 1 AGONIST; SUMATRIPTAN; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL TISSUE; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTICLE; BASILAR ARTERY; BLOOD VESSEL INNERVATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DESENSITIZATION; ELECTROSTIMULATION; ISOLATED ARTERY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION;

ANIMALS; BASILAR ARTERY; CALCITONIN GENE-RELATED PEPTIDE; CAPSAICIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; HUMANS; MALE; OXAZOLES; PEPTIDE FRAGMENTS; PYRROLIDINES; RABBITS; RECEPTORS, CALCITONIN GENE-RELATED PEPTIDE; RECEPTORS, VASOACTIVE INTESTINAL PEPTIDE; SEROTONIN AGONISTS; SUMATRIPTAN; VASOACTIVE INTESTINAL PEPTIDE; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATION;

EID: 0034696883     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00153-9     Document Type: Article

References (29)

1. Caterina M.J., Schumacher M.A., Tominaga M., Rosen T.A., Levine J.D., Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature. 389:1997;816-824.
2. Edvinsson L., Fredholm B.B., Hamel E., Jansen I., Verrecchia C. Perivascular peptides relax cerebral arteries concomitant with stimulation of cyclic adenosine monophosphate accumulation or release of endothelium derived relaxing factor. Neurosci. Lett. 58:1985;213-217.
3. Edvinsson L., Jansen I. Vasomotor responses and receptor characterisation of human cranial arteries and veins. Olesen J., Tfelt-Hansen P., Welch K.M.A. The Headaches. 1993;117-127 Raven Press, New York.
4. Goadsby P.J., Edvinsson L. The trigeminovascular system and migraine: studies characterising cerebrovascular and neuropeptide changes seen in humans and cats. Ann. Neurol. 33:1993;48-56.
5. Goadsby P.J., Edvinsson L. Human in vivo evidence for trigeminovascular activation in cluster headache. Neuropeptide changes and effects of acute attacks therapies. Brain. 117:1994;427-434.
6. Goadsby P.J., Edvinsson L., Ekman R. Vasoactive peptide release in the extracerebral circulation of humans during migraine headache. Ann. Neurol. 28:1990;183-187.
7. Goadsby P.J., Knight Y.E., Hoskin K.L., Butler P. Stimulation of an intracranial trigeminally-innervated structure selectively increases cerebral blood flow. Brain Res. 751:1997;247-252.
8. Goadsby P.J., Lambert G.A., Lance J.W. Stimulation of the trigeminal ganglion increases flow in the extracerebral but not the cerebral circulation of the monkey. Brain Res. 381:1986;63-67.
9. Humphrey P.P.A., Feniuk W. Mode of action of the anti-migraine drug sumatriptan. Trends Pharmacol. Sci. 12:1991;444-446.
10. Kurosawa M., Messlinger K., Pawlak M., Schmidt R.F. Increase of meningeal blood flow after electrical stimulation of rat dura mater encephala: mediation by calcitonin gene-related peptide. Br. J. Pharmacol. 114:1995;1397-1402.
11. Lambert G.A., Bogduk N., Goadsby P.J., Duckworth J.W., Lance J.W. Decreased carotid arterial resistance in cats in response to trigeminal stimulation. J. Neurosurg. 61:1984;307-315.
12. Longmore J., Dowson A.J., Hill R.G. Advances in migraine therapy - 5-HT receptor subtype specific agonists. Curr. Opin. CPNS Invest. Drugs. 1:1999;39-53.
13. Longmore J., Hogg J.E., Hutson P.H., Hill R.G. Comparison of the effects of αhCGRP (8-37) and βhCGRP (8-37) on αhCGRP evoked responses in isolated tissue preparations and SK-N-MC cells: implications for receptor classification. Eur. J. Pharmacol. 265:1994;53-59.
14. 1D-immunoreactivity within the human trigemino-cerebrovascular system: implications for the discovery of new anti-migraine drugs. Cephalalgia. 17:1997;833-842.
15. Lynn B. Efferent functions of nociceptors. Belmonte C., Cervero F. Neurobiology of Nociceptors. 1996;418-438 Oxford Univ. Press.
16. 1D Receptor Agonist PNU-142633. Presented at IBC Migraine Conference, Philadelphia, April 1999:1999.
17. Moskowitz M.A. Neurogenic versus vascular mechanisms of sumatriptan and ergot alkaloids in migraine. Trends Pharmacol. Sci. 13:1992;307-312.
18. 1B/D receptors ligands: an answer from GTPγs binding studies with stably transfected C6-glial cell lines. Neuropharmacology. 35:1997;499-512.
19. Poyner D. Pharmacological receptors for calcitonin gene-related peptide and amylin. Trends Pharmacol. Sci. 16:1995;424-428.
20. Ray B.S., Wolff H.G. Experimental studies on headache. Pain sensitive structures of the head and their significance in headache. Arch. Surg. 41:1940;813-856.
21. Razzaque Z., Longmore J., Hill R.G. Differences in the effects of ketanserin and GR127935 on 5-HT receptor mediated responses in rabbit saphenous vein and guinea-pig jugular vein. Eur. J. Pharmacol. 283:1995;199-206.
22. 1Dβ-receptor binding affinity. Br. J. Pharmacol. 119:1996;. 112 pp.
23. 1B receptor. J. Med. Chem. 42:1999;677-690.
24. Tilford N.S., Baxter G.S. The actions of ketanserin and ritanserin on contractile responses to sumatriptan in rabbit basilar artery. Br. J. Pharmacol. 112:1994;. 478 pp.
25. Tran-Dinh Y.R., Thurel C., Cunin G., Serrie A., Seylaz J. Cerebral vasodilation after the thermocoagulation of the trigeminal ganglion in humans. Neurosurgery. 31:1992;658-662.
26. Uddman R., Edvinsson L. Neuropeptide in the cerebral circulation. Cerebrovasc. Brain Metab. Rev. 1:1989;230-252.
27. Van Rossum D., Hanisch U.-K., Quirion R. Neuroanatomical localisation, pharmacological characterisation and functions of CGRP, related peptides and their receptors. Neurosci. Behav. Rev. 21:1997;649-678.
28. Williamson D.J., Hargreaves R.J., Hill R.G., Shepheard S.L. Sumatriptan inhibits neurogenic vasodilation of dural blood vessels in the anaesthetised rat-intravital microscope studies. Cephalalgia. 17:1997;526-531.
29. Williamson D.J., Hargreaves R.J., Hill R.G., Shepheard S.L. Intravital microscope studies on the effects of neurokinin agonists and calcitonin gene-related peptide on dural vessel diameter in the anaesthetised rat. Cephalalgia. 17:1997;518-524.