-
1
-
-
0028943734
-
Apoptosis and the pathogenesis and treatment of disease
-
Thompson C. B. Apoptosis and the pathogenesis and treatment of disease. Science. 267:1995;1456-1462.
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.B.1
-
2
-
-
0028040019
-
Cellular mechanisms of disease series
-
Reed J. C. Cellular mechanisms of disease series. J. Cell Biol. 124:1994;1-6.
-
(1994)
J. Cell Biol.
, vol.124
, pp. 1-6
-
-
Reed, J.C.1
-
3
-
-
0030931876
-
Caspases: The executioners of apoptosis
-
Cohen G. M. Caspases: The executioners of apoptosis. Biochem. J. 326:1997;1-16.
-
(1997)
Biochem. J.
, vol.326
, pp. 1-16
-
-
Cohen, G.M.1
-
4
-
-
0030814675
-
Caspases: Killer proteases
-
Nicholson D. W., Thornberry N. A. Caspases: Killer proteases. TIBS. 22:1997;299-306.
-
(1997)
TIBS
, vol.22
, pp. 299-306
-
-
Nicholson, D.W.1
Thornberry, N.A.2
-
5
-
-
0029670265
-
ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis
-
Nicholson D. W. ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis. Nature Biotech. 14:1996;297-301.
-
(1996)
Nature Biotech.
, vol.14
, pp. 297-301
-
-
Nicholson, D.W.1
-
6
-
-
0030849093
-
A combinatorial approach defines specificities of members of the caspase family and granzyme B: Functional relationships established for key mediators of apoptosis
-
Thornberry N. A., Rano T. A., Peterson E. P., Rasper D. M., Timkey T., Garcia-Calvo M., Houtzager V. M., Nordstrom P. A., Roy S., Vaillancourt J. P., Chapman K. T., Nicholson D. W. A combinatorial approach defines specificities of members of the caspase family and granzyme B: Functional relationships established for key mediators of apoptosis. J. Biol. Chem. 272:1997;17907-17911.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17907-17911
-
-
Thornberry, N.A.1
Rano, T.A.2
Peterson, E.P.3
Rasper, D.M.4
Timkey, T.5
Garcia-Calvo, M.6
Houtzager, V.M.7
Nordstrom, P.A.8
Roy, S.9
Vaillancourt, J.P.10
Chapman, K.T.11
Nicholson, D.W.12
-
7
-
-
0028924496
-
Involvement of multiple proteases during Fas-mediated apoptosis in T lymphocytes
-
Chow S. C., Weis M., Kass G. E. N., Holmström T. H., Eriksson J. E., Orrenius S. Involvement of multiple proteases during Fas-mediated apoptosis in T lymphocytes. FEBS Lett. 364:1995;134-138.
-
(1995)
FEBS Lett.
, vol.364
, pp. 134-138
-
-
Chow, S.C.1
Weis, M.2
Kass, G.E.N.3
Holmström, T.H.4
Eriksson, J.E.5
Orrenius, S.6
-
8
-
-
0029944142
-
Role of CED-3/ICE-family proteases in staurosporine-induced programmed cell death
-
Jacobson M. D., Weil M., Raff M. C. Role of CED-3/ICE-family proteases in staurosporine-induced programmed cell death. J. Cell Biol. 133:1996;1041-1051.
-
(1996)
J. Cell Biol.
, vol.133
, pp. 1041-1051
-
-
Jacobson, M.D.1
Weil, M.2
Raff, M.C.3
-
9
-
-
0030002801
-
Benzyloxycarbonyl-val-ala-asp (OMe) fluoromethylketone (z-VAD-FMK) inhibits apoptosis by blocking the processing of CPP32
-
Slee E. A., Zhu H., Chow S. C., MacFarlane M., Nicholson D. W., Cohen G. M. Benzyloxycarbonyl-val-ala-asp (OMe) fluoromethylketone (z-VAD-FMK) inhibits apoptosis by blocking the processing of CPP32. Biochem. J. 315:1996;21-24.
-
(1996)
Biochem. J.
, vol.315
, pp. 21-24
-
-
Slee, E.A.1
Zhu, H.2
Chow, S.C.3
MacFarlane, M.4
Nicholson, D.W.5
Cohen, G.M.6
-
10
-
-
0030925774
-
Flice is activated by association with the CD95 death-inducing signaling complex (DISC)
-
Medema J. P., Scaffidi C., Kischkel F. C., Shevchenko A., Mann M., Krammer P. H., Peter M. E. Flice is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J. 16:1997;2794-2804.
-
(1997)
EMBO J.
, vol.16
, pp. 2794-2804
-
-
Medema, J.P.1
Scaffidi, C.2
Kischkel, F.C.3
Shevchenko, A.4
Mann, M.5
Krammer, P.H.6
Peter, M.E.7
-
11
-
-
0029853199
-
Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death
-
Rodriguez I., Matsuura K., Ody C., Nagata S., Vassalli P. Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death. J. Exp. Med. 184:1996;2067-2072.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 2067-2072
-
-
Rodriguez, I.1
Matsuura, K.2
Ody, C.3
Nagata, S.4
Vassalli, P.5
-
12
-
-
1842407161
-
Inhibition of ICE slows ALS in mice
-
Friedlander R. M., Brown R. H., Gagliardini V., Wang J., Yuan J. Inhibition of ICE slows ALS in mice. Nature. 388:1997;31.
-
(1997)
Nature
, vol.388
, pp. 31
-
-
Friedlander, R.M.1
Brown, R.H.2
Gagliardini, V.3
Wang, J.4
Yuan, J.5
-
13
-
-
0031009716
-
Caspase activity is required for commitment to Fas-mediated apoptosis
-
Longthorne V. L., Williams G. T. Caspase activity is required for commitment to Fas-mediated apoptosis. EMBO J. 16:1997;3805-3812.
-
(1997)
EMBO J.
, vol.16
, pp. 3805-3812
-
-
Longthorne, V.L.1
Williams, G.T.2
-
14
-
-
0033603847
-
Effects of differential overexpression of Bcl-2 on apoptosis, proliferation and teleomerase activity in Jurkat T cells
-
Johnson V. L., Cooper I. R., Jenkins J. R., Chow S. C. Effects of differential overexpression of Bcl-2 on apoptosis, proliferation and teleomerase activity in Jurkat T cells. Exp. Cell Res. 252:1999;175-184.
-
(1999)
Exp. Cell Res.
, vol.252
, pp. 175-184
-
-
Johnson, V.L.1
Cooper, I.R.2
Jenkins, J.R.3
Chow, S.C.4
-
15
-
-
0030826338
-
FLICE is predominantly expressed as two functionally active isoforms, caspase-8/α and caspase-8/β
-
Scaffidi C., Medema J. P., Krammer P. H., Peter M. E. FLICE is predominantly expressed as two functionally active isoforms, caspase-8/α and caspase-8/β J. Biol. Chem. 272:1997;26953-26958.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26953-26958
-
-
Scaffidi, C.1
Medema, J.P.2
Krammer, P.H.3
Peter, M.E.4
-
16
-
-
0028795758
-
Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)
-
Dhein J., Walczak H., Bäumier C., Debatin K.-M., Krammer P. H. Autocrine T-cell suicide mediated by APO-1/(Fas/CD95). Nature. 373:1995;438-441.
-
(1995)
Nature
, vol.373
, pp. 438-441
-
-
Dhein, J.1
Walczak, H.2
Bäumier, C.3
Debatin, K.-M.4
Krammer, P.H.5
-
17
-
-
0029905761
-
Release of preformed Fas ligand in soluble form is the major factor for activation-induced death of Jurkat cells
-
Martinez-Lorenzo M. J., Alava M. A., Anel A., Pineiro A., Naval J. Release of preformed Fas ligand in soluble form is the major factor for activation-induced death of Jurkat cells. Immunol. 89:1996;511-517.
-
(1996)
Immunol.
, vol.89
, pp. 511-517
-
-
Martinez-Lorenzo, M.J.1
Alava, M.A.2
Anel, A.3
Pineiro, A.4
Naval, J.5
-
18
-
-
15844412409
-
Flice, a novel Fadd-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/Apo-1) death-inducing signaling complex
-
Muzio M., Chinnaiyan A. M., Kischkel F. C., Orourke K., Shevchenko A., Ni J., Scaffidi C., Bretz J. D., Zhang M., Gentz R., Mann M., Krammer P. H., Peter M. E., Dixit V. M. Flice, a novel Fadd-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/Apo-1) death-inducing signaling complex. Cell. 85:1996;817-827.
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
Orourke, K.4
Shevchenko, A.5
Ni, J.6
Scaffidi, C.7
Bretz, J.D.8
Zhang, M.9
Gentz, R.10
Mann, M.11
Krammer, P.H.12
Peter, M.E.13
Dixit, V.M.14
-
19
-
-
0030011398
-
Involvement of Mach, a novel Mort1/Fadd-interacting protease, in Fas/APO-1 and TNF receptor-induced cell death
-
Boldin M. P., Goncharov T. M., Goltsev Y. V., Wallach D. Involvement of Mach, a novel Mort1/Fadd-interacting protease, in Fas/APO-1 and TNF receptor-induced cell death. Cell. 85:1996;803-815.
-
(1996)
Cell
, vol.85
, pp. 803-815
-
-
Boldin, M.P.1
Goncharov, T.M.2
Goltsev, Y.V.3
Wallach, D.4
-
20
-
-
0032536519
-
Caspase are activated in a branch protease cascade and control distinct downstream process in Fas-induced apoptosis
-
Hirata H., Takahashi A., Kobayashi S., Yonehara S., Sawai H., Okazaki T., Yamamoto K., Sasada M. Caspase are activated in a branch protease cascade and control distinct downstream process in Fas-induced apoptosis. J. Exp. Med. 187:1998;587-600.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 587-600
-
-
Hirata, H.1
Takahashi, A.2
Kobayashi, S.3
Yonehara, S.4
Sawai, H.5
Okazaki, T.6
Yamamoto, K.7
Sasada, M.8
-
22
-
-
0026575932
-
The mechanism of action of cyclosporin A and FK506
-
Schreiber S. L., Crabtree G. R. The mechanism of action of cyclosporin A and FK506. Immunol. Today. 13:1992;136-142.
-
(1992)
Immunol. Today
, vol.13
, pp. 136-142
-
-
Schreiber, S.L.1
Crabtree, G.R.2
-
23
-
-
0028926511
-
The regulation and function of p21(ras) during T-cell activation and growth
-
Izquierdo Pastor M., Reif K., Cantrell D. The regulation and function of p21(ras) during T-cell activation and growth. Immunol. Today. 16:1995;159-164.
-
(1995)
Immunol. Today
, vol.16
, pp. 159-164
-
-
Izquierdo Pastor, M.1
Reif, K.2
Cantrell, D.3
-
24
-
-
0026643141
-
Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation
-
Clipstone N. A., Crabtree G. R. Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. Nature. 357:1992;695-697.
-
(1992)
Nature
, vol.357
, pp. 695-697
-
-
Clipstone, N.A.1
Crabtree, G.R.2
-
25
-
-
0027959722
-
Molecular and genetic insights into T cell antigen receptor signal transduction
-
Weiss A., Iwashima M., Irving B., Van Oers N. S. C., Kadlecek T. A., Straus D., Chan A. Molecular and genetic insights into T cell antigen receptor signal transduction. Adv. Exp. Med. Biol. 65:1994;53-62.
-
(1994)
Adv. Exp. Med. Biol.
, vol.65
, pp. 53-62
-
-
Weiss, A.1
Iwashima, M.2
Irving, B.3
Van Oers, N.S.C.4
Kadlecek, T.A.5
Straus, D.6
Chan, A.7
-
26
-
-
0029906828
-
Bax-induced cell death may not require interleukin 1beta-converting enzyme-like proteases
-
Xiang J., Chao D. T., Korsmeyer S. J. Bax-induced cell death may not require interleukin 1beta-converting enzyme-like proteases. Proc. Natl. Acad. Sci. USA. 93:1996;14559-14563.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14559-14563
-
-
Xiang, J.1
Chao, D.T.2
Korsmeyer, S.J.3
-
27
-
-
0031033274
-
Inhibition of CED-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak
-
McCarthy N. J., Whyte M. K. B., Gilbert C. S., Evan G. I. Inhibition of CED-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak. J. Cell Biol. 136:1997;215-227.
-
(1997)
J. Cell Biol.
, vol.136
, pp. 215-227
-
-
McCarthy, N.J.1
Whyte, M.K.B.2
Gilbert, C.S.3
Evan, G.I.4
-
28
-
-
0030994236
-
Evidence for CPP32 activation in the absence of apoptosis during T lymphocyte stimulation
-
Miossec C., Dutilleul V., Fassy F., Diu-Hercend A. Evidence for CPP32 activation in the absence of apoptosis during T lymphocyte stimulation. J. Biol. Chem. 272:1997;13459-13462.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13459-13462
-
-
Miossec, C.1
Dutilleul, V.2
Fassy, F.3
Diu-Hercend, A.4
-
29
-
-
0032494143
-
Dual signaling of the Fas receptor: Initiator of both apoptotic and necrotic cell death pathways
-
Vercammen D., Brouckaert G., Denecker G., Van der Craen M., Declerq W., Fiers W., Vandenbeele P. Dual signaling of the Fas receptor: Initiator of both apoptotic and necrotic cell death pathways. J. Exp. Med. 188:1998;919-930.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 919-930
-
-
Vercammen, D.1
Brouckaert, G.2
Denecker, G.3
Van Der Craen, M.4
Declerq, W.5
Fiers, W.6
Vandenbeele, P.7
|