Self-selection by genetically modified committed lymphocyte precursors reverses the phenotype of JAK3-deficient mice without myeloablation

Human Gene Therapy

Volumn 11, Issue 17, 2000, Pages 2353-2364

  Bunting, K D ^a,b   Lu, T ^a   Kelly, P F ^a   Sorrentino, B P ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b HOLLAND LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

JANUS KINASE; VIRUS VECTOR; JAK3 PROTEIN, MOUSE; JANUS KINASE 3; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; GENE THERAPY; HEMATOPOIETIC STEM CELL; INFLUENZA VIRUS A; MOUSE; NEWBORN; NONHUMAN; PHENOTYPE; PROLYMPHOCYTE; RETROVIRUS; VIRUS INFECTION; ANIMAL; ANTIBODY PRODUCTION; BONE MARROW CELL; CELL TRANSPLANTATION; CYTOLOGY; GENE VECTOR; GENETIC SELECTION; GENETICS; IMMUNOLOGY; LIVER; LYMPHOCYTE; METHODOLOGY; MOUSE MUTANT; ORTHOMYXOVIRUS INFECTION; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; SURVIVAL RATE;

ANIMALS; ANIMALS, NEWBORN; ANTIBODY FORMATION; CELL TRANSPLANTATION; GENE THERAPY; GENETIC VECTORS; HEMATOPOIETIC STEM CELLS; INFLUENZA A VIRUS; JANUS KINASE 3; LIVER; LYMPHOCYTES; MICE; MICE, MUTANT STRAINS; MYELOID CELLS; ORTHOMYXOVIRIDAE INFECTIONS; PHENOTYPE; PROTEIN-TYROSINE KINASES; RETROVIRIDAE; SELECTION (GENETICS); SEVERE COMBINED IMMUNODEFICIENCY; SURVIVAL RATE;

EID: 0034694076     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/104303400750038462     Document Type: Article

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