Blockade of voltage-sensitive Na+ channels by the 5-HT(1A) receptor agonist 8-OH-DPAT: Possible significance for neuroprotection

European Journal of Pharmacology

Volumn 406, Issue 3, 2000, Pages 319-324

  Melena, José ^a   Chidlow, Glyn ^a   Osborne, Neville N ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

5 HT(1A) receptor; 8 OH DPAT; Ca2+ channel; Ischemia; Na+ channel; Neuroprotection

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; BATRACHOTOXIN; BUSPIRONE; CALCIUM ION; FLESINOXAN; IODINE 125; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; OMEGA CONOTOXIN MVIIA; OMEGA CONOTOXIN MVIIC; SAXITOXIN; SEROTONIN 1A AGONIST; SEROTONIN 1A ANTAGONIST; SODIUM ION; TETRODOTOXIN; TRITIUM; VERATRIDINE;

ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN PROTECTION; ION CHANNEL; LIGAND BINDING; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; RAT; SEROTONINERGIC SYSTEM; SODIUM CHANNEL; SODIUM TRANSPORT;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMAL; BATRACHOTOXINS; CALCIUM; NEUROPROTECTIVE AGENTS; OMEGA-CONOTOXINS; PIPERAZINES; PYRIDINES; RATS; SAXITOXIN; SEROTONIN AGONISTS; SODIUM; SODIUM CHANNEL BLOCKERS; SUPPORT, NON-U.S. GOV'T;

EID: 0034693242     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00688-9     Document Type: Article

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