Neuroprotection against N-methyl-D-aspartate-induced excitotoxicity in rat magnocellular nucleus basalis by the 5-HT(1A) receptor agonist 8-OH-DPAT

European Journal of Pharmacology

Volumn 358, Issue 2, 1998, Pages 147-152

  Oosterink, Bart J ^a   Mechiel Korte, S ^a   Nyakas, Csaba ^a,b   Korf, Jakob ^a   Luiten, Paul G M ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

5 HT(1A) receptor; 8 OH DPAT; Excitotoxicity; Homeothermic condition; Neuroprotection; NMDA (N methyl D aspartate)

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; IPSAPIRONE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; N METHYL DEXTRO ASPARTIC ACID; SEROTONIN 1A AGONIST;

ANIMAL EXPERIMENT; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; DRUG EFFECT; HYPERPOLARIZATION; INTRAPERITONEAL DRUG ADMINISTRATION; MAGNOCELLULAR NUCLEUS; MALE; NERVE INJURY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ACETYLCHOLINESTERASE; ANIMALS; EXCITATORY AMINO ACID AGONISTS; MALE; N-METHYLASPARTATE; NEUROPROTECTIVE AGENTS; PYRIMIDINES; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN AGONISTS; SUBSTANTIA INNOMINATA;

EID: 0031717754     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00614-1     Document Type: Article

References (32)

1. 1A antagonists. Trends Neurosci. 19:1996;378.
2. Becquet D., Hery M., Deprez P., Faudon M., Fache M.P., Giraud P., Hery F. N-methyl-D-aspartic acid/glycine interactions of the control of 5-hydroxy-tryptamine release in raphe primary cultures. J. Neurochem. 61:1993;1692.
3. Bowen D.M., Najlerahim A., Procter A.W., Francis P.T., Murphy E. Circumscribed changes of the cerebral cortex in neuropsychiatric disorders of later life. Proc. Natl. Acad. Sci. USA. 86:1989;9504.
4. Bowen D.M., Francis P.T., Pangalos M.N., Stephens P.H., Procter A.W. Treatment strategies for Alzheimer's disease. The Lancet. 339:1992;132.
5. Choi D.W. Calcium: still center-stage in hypoxic-ischemic neuronal death. Trends Neurosci. 18:1995;58.
6. Dodd P.R., Scott H.L., Westphalen R.I. Excitotoxic mechanism in the pathogenesis of dementia. Neurochem. Int. 3:1994;203.
7. 2 receptors: microdialysis studies in the awake and anaesthetized rat. Neuropharmacology. 33:1994;411.
8. Fort P., Khateb A., Pegna A., Mühlethaler M., Jones D.E. Noradrenergic modulation of cholinergic nucleus basalis neurons demonstrated by in vitro pharmacological and immunohistochemical evidence in the guinea-pig brain. Eur. J. Neurosci. 7:1995;1502.
9. 1A receptor. Biochemistry. 33:1994;4283.
10. Greiner C., Hülsmann S., Wassmann H., Mosskopp D., Schmidinger A., Wölfer A., Köhling R., Lücke A., Speckmann E.-J. Neuroprotection of mild hypothermia: differential effects. Brain Res. 786:1998;267.
11. Hedreen J.C., Bacon S.J., Price D.L. A modified histochemical technique to visualize acetylcholinesterase-containing axons. J. Histochem. Cytochem. 33:1985;134.
12. Khateb A., Fort P., Alonso A., Jones D.E., Mühlethaler M. Pharmacological and immunohistochemical evidence for serotonergic modulation of cholinergic nucleus basalis neurons. Eur. J. Neurosci. 5:1993;541.
13. 1A receptors are expressed by a subpopulation of cholinergic neurons in the rat medial septum and diagonal band of Broca - a double immunocytochemical study. Neuroscience. 74:1996;14.
14. 2+ antagonist nimodipine, influence of aging and developmental drug treatment. Neurodegeneration. 4:1995;307.
15. Middlemiss D.N., Palmer A.M., Edel N., Bowen D.M. Binding of the novel serotonin agonist 8-hydroxy-2-(di-n-propylamino)tetralin in normal and Alzheimer brain. J. Neurochem. 46:1986;993.
16. Nocon H., Daniel W., Danek L., Melzacka M. Cerebral pharmacokinetics of ipsapirone in rats after different routes of administration. J. Pharm. Pharmacol. 42:1990;642.
17. 1A receptor binding sites in rat cortex, hippocampus and cholinergic basal forebrain nuclei during aging. J. Chem. Neuroanat. 13:1997;53.
18. 1A receptor activation. Br. J. Pharmacol. 106:1992;603.
19. 2+-induced neurodegeneration in rat nucleus basalis. In: Teelken, A., Korf, J. (Eds.), Neurochemistry: Cellular, Molecular and Clinical Aspects. Plenum, London, pp. 401-406.
20. Paxinos, G., Watson, C., 1989. The Rat Brain in Stereotaxic Coordinates, Academic Press, Sydney.
21. 11C ]WAY100635 Eur. J. Pharmacol. 301:1996;R5.
22. Prehn J.H., Welsch M., Backhauß C., Nuglish J., Ausmeier F., Karkoutly C., Krieglstein J. Effects of serotonergic drugs in experimental brain ischemia. Brain Res. 630:1993;10.
23. 1A receptor-induced attenuation of postsynaptic responses in the rat in vivo. Naunyn-Schmiedeberg's Arch. Pharmacol. 346:1992;138.
24. Rothman S.M., Olney J.W. Excitotoxicity and the NMDA-receptor-still lethal after eight years. Trends Neurosci. 18:1995;57.
25. Sparks D.L., Hunsaker J.C., Slevin J.T., DeKosky S.T., Kryscio R.J., Markesbery W.R. Monoaminergic and cholinergic synaptic markers in the nucleus basalis (nbM): normal age-related changes and the effect of heart disease and Alzheimer's disease. Ann. Neurol. 31:1992;611.
26. 2 agonists. Synapse. 1:1987;3.
27. Srkalovic G., Selim M., Rea M.A., Glass J.D. Serotonergic inhibition of extracellular glutamate in the suprachiasmatic nuclear region assessed using in vivo brain microdialysis. Brain Res. 656:1994;302.
28. 2+- and glutamatergic receptor-evoked arachidonic acid and NO/cGMP release in adult hippocampus. Neurochem. Int. 28:1996;439.
29. Stuiver B.T., Douma B.R.K., Bakker R., Nyakas C., Luiten P.G.M. In vivo protection against NMDA-induced neurodegeneration by MK-801 and nimodipine: combined therapy and temporal course of protection. Neurodegeneration. 5:1996;153.
30. Verkhratsky A., Toescu E.C. Calcium and neuronal ageing. Trends Neurosci. 21:1997;2.
31. 1A receptor ligands. J. Med. Chem. 41:1998;157.
32. Zornow M.H. Inhibition of glutamate release: a possible mechanism of hypothermic neuroprotection. J. Neurosurg. Anesthesiol. 7:1995;148.