Blockade of voltage-sensitive sodium channels by NS-7, a novel neuroprotective compound, in the rat brain

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 355, Issue 5, 1997, Pages 601-608

  Shimidzu, Takako ^a   Itoh, Yoshinori ^a   Tatsumi, Shigeru ^a   Hayashi, Seiji ^a   Ukai, Yojiro ^a   Yoshikuni, Yoshiaki ^a   Kimura, Kiyoshi ^a  

^a NIPPON SHINYAKU CO LTD   (Japan)

Author keywords

Batrachotoxin; Cardiac myocyte; Cerebral cortex; Glutamate release; Neuroprotectant; Saxitoxin; Voltage sensitive sodium channel

Indexed keywords

4 (4 FLUOROPHENYL) 2 METHYL 6 (5 PIPERIDINOPENTYLOXY)PYRIMIDINE; ACONITINE; BATRACHOTOXININ A 20ALPHA BENZOATE; LAMOTRIGINE; NEUROPROTECTIVE AGENT; PHENYTOIN; PROCAINE; SAXITOXIN; SODIUM CHANNEL; UNCLASSIFIED DRUG; VERATRIDINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN MEMBRANE; CONTROLLED STUDY; HEART MUSCLE CELL; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; RAT;

ACONITINE; ANALYSIS OF VARIANCE; ANIMALS; BATRACHOTOXINS; BINDING, COMPETITIVE; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTAMIC ACID; HEART; INJECTIONS, INTRAVENOUS; MALE; MYOCARDIUM; NEUROPROTECTIVE AGENTS; NEUROTOXINS; POTASSIUM CHLORIDE; PYRIMIDINES; RATS; RATS, WISTAR; SAXITOXIN; SODIUM CHANNELS; SYNAPTOSOMES; VERATRIDINE;

EID: 0030941528     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00004990     Document Type: Article

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