Presidential address to The American Association of Immunologists: The road less traveled by: The role of innate immunity in the adaptive immune response

Journal of Immunology

Volumn 161, Issue 2, 1998, Pages 539-544

  Janeway Jr , Charles A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; PROTEIN SERINE THREONINE KINASE;

ADAPTATION; CAENORHABDITIS ELEGANS; DROSOPHILA; HUMAN; IMMUNE RESPONSE; IMMUNITY; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; T LYMPHOCYTE ACTIVATION;

ALLERGY AND IMMUNOLOGY; ANIMALS; AUTOBIOGRAPHY; HISTORY, 19TH CENTURY; HISTORY, 20TH CENTURY; HUMANS; IMMUNITY, ACTIVE; IMMUNITY, NATURAL; INFECTION; PORTRAITS; SOCIETIES, MEDICAL; UNITED STATES;

EID: 2642618620     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (6)

1. Janeway, C. A., Jr. 1989. Approaching the asymptote?: evolution and revolution in immunology. Cold Spring Harbor Symp. Quant. Biol. 54:1.
2. Liu, Y., and C. A. Janeway, Jr. 1992. Cells that present both specific ligand and costimulatory activity are the most efficient inducers of clonal expansion of normal CD4 T cells. Proc. Natl. Acad. Sci. USA 89:3845.
3. Lemaitre, B., E. Nicolas, L. Michaut, J. M. Reichart, and J. A. Hoffmann. 1996. The dorsoventral regulatory gene casette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86:973.
4. Medzhitov, R. M., and C. A. Janeway, Jr. 1998. An ancient system of host defense. Curr. Opin. Immunol. 10:12.
5. Medzhitov, R. M., P. Preston-Hurlburt, and C. A. Janeway, Jr. 1997. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388:394.
6. Fearon, D. T., and R. M. Locksley. 1996. The instructive role of innate immunity in the acquired immune response. Science 272:50.