Induced κ receptor editing shows no allelic preference in a mouse pre-B cell line

Journal of Immunology

Volumn 165, Issue 12, 2000, Pages 7058-7063

  Liu, X ^a   Linden, M ^a   Van Ness, B ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; IMMUNOGLOBULIN HEAVY CHAIN;

ALLELE; ANIMAL CELL; ANTIGEN RECOGNITION; ARTICLE; B LYMPHOCYTE; CELL MATURATION; CONTROLLED STUDY; GENE LOCUS; GENE REARRANGEMENT; GENE TARGETING; GENETIC TRANSFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING;

EID: 0034671951     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.12.7058     Document Type: Article

References (29)

1. B-cell-receptor-dependent positive and negative selection in immature B cells
2. Corrective recombination of mouse immunoglobulin κ alleles in Abelson murine leukemia virus-transformed pre-B cells
3. Receptor editing, immune diversification, and self-tolerance
4. Immunoglobulin heavy chain gene replacement a mechanism of receptor editing
5. Light chain replacement a new model for antibody gene rearrangement
6. Functional immunoglobulin light chain genes are replaced by ongoing rearrangements of germline Vk genes to downstream Jk segment in a murine B cell Line
7. Receptor editing occurs frequently during B cell development
8. Activation of immunoglobulin κ gene rearrangement correlates with induction of germline κ gene transcription
9. Coordinate transcription and V(D)J recombination of the κ immunoglobulin light-chain locus NF-kB-dependent and independent pathways of activation
10. Down-regulation of RAG1 and RAG2 gene expression in pre-B cells after functional immunoglobulin heavy chain rearrangement
11. V(D)J recombinase activity in a subset of germinal center B lymphocytes
12. κ Chain monoallelic demethylation and the establishment of allelic exclusion
13. Receptor editing and commitment in B lymphocytes
14. Changes in locus-specific V(D)J recombinase activity induced by immunoglobulin gene products during B cell development
15. Roles of IgH and L chains and of surrogate H and L chains in the development of cells of the B lymphocyte lineage
16. Immunoglobulin heavy-chain protein controls B cell development by regulating germline transcription and retracting V(D)J recombination
17. Functional immunoglobulin transgenes guide ordered B-cell differentiation in RAG-1-deficient mice
18. Influence of immunoglobulin heavy- and light-chain expression on B-cell differentiation
19. A theory of allelic and isotype exclusion for immunoglobulin genes
20. Allelic exclusion model questioned (I)
21. Immune receptor editing revise and select
22. Development of B-1 cells segregation of phosphatidylcholine-specific B cells to the B-1 population occurs after immunoglobulin gene expression
23. RAG-1-deficient mice have no mature B and T lymphocytes
24. RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination
25. V(D)J recombination molecular biology and regulation
26. Models for antigen receptor gene rearrangement 1 Biased receptor editing in B cells implications for allelic exclusion
27. Transcription of the unrearranged mouse Cκ locus sequence structure of the initiation region and comparison of activity with a rearranged Vκ-Cκ gene
28. The coupling between enhancer activity and hypomethylation of κ immunoglobulin genes is developmentally regulated
29. The importance of the 3'-enhancer region in immunoglobulin κ gene expression