Quantitative histology and cytochrome P-450 immunocytochemistry of the lung parenchyma following 6 months of exposure of strain A/J mice to cigarette sidestream smoke

Inhalation Toxicology

Volumn 8, Issue 9, 1996, Pages 927-945

  Pinkerton, Kent E ^a   Peake, Janice L ^a   Espiritu, Imelda ^a   Goldsmith, Michael ^a   Witschi, Hanspeter ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0030471649     PISSN: 08958378     EISSN: None     Source Type: Journal    
DOI: 10.3109/08958379609034271     Document Type: Article

References (42)

1. Adams, J. D., O'Mara-Adams, K. J., and Hoffmann, D. 1987. Toxic and carcinogenic agents in undiluted mainstream smoke and sidestream smoke of different types of cigarettes. Carcinogenesis 8:729-731.
2. Anandatheerthavarada, H. K., Williams, J. F., and Wecker, L. 1993. Differential effect of chronic nicotine administration on brain cytochrome P4501A1/2 and P4502E1. Biochem. Biophys. Res. Commun. 194:312-318.
3. Bolender, R. P., Hyde, D. M., and Dehoff, R. T. 1993. Lung morphometry: a new generation of tools and experiments for organ, tissue, cell, and molecular biology. Am. J. Physiol. 265:L521-L548.
4. Bonham, G. S., and Wilson, R. W. 1981. Children's health in families with cigarette smokers. Am. J. Public Health 71:290-293.
5. Buckpitt, A., Chang, A. M., Weir, A., Van Winkle, L., Duan, X., Philpot, R., and Plopper, C. 1995. Relationship of cytochrome P450 activity to Clara cell cytotoxicity. IV. Metabolism of naphthalene and naphthalene oxide in microdissected airways from mice, rats, and hamsters. Mol. Pharmacol. 47:74-81.
6. Coggins, C. R., Ayres, P. H., Mosberg, A. T., Ogden, M. W., Sagartz, J. W., and Hayes, A. W. 1992. Fourteen-day inhalation study in rats, using aged and diluted sidestream smoke from a reference cigarette. I. Inhalation toxicology and histopathology. Fundam. Appl. Toxicol. 19:133-140.
7. Coggins, C. R., Ayres, P. H., Mosberg, A. T., Sagartz, J. W., and Hayes, A. W. 1993. Subchronic inhalation study in rats using aged and diluted sidestream smoke from a reference cigarette, Inhal. Toxicol. 5:77-96.
8. Cruz-Orive, L. M. 1990. On the empirical variance of a fractionator estimate. J. Microsc. 160:89-95.
9. De Vito, M. J., Maier, W. E., Diliberto, J. J., and Birnbaum, L. S. 1993, Comparative ability of various PCBs, PCDFs, and TCDD to induce cytochrome P450 1A1 and 1A2 activity following 4 weeks of treatment. Fundam. Appl. Toxicol. 20:125-130.
10. Ekwo, E. E., Weinberger, M. M., Lachenbruch, P. A., and Huntley, W. H. 1983. Relationship of parental smoking and gas cooking to respiratory disease in children. Chest 84:662-668.
11. Finch, G. L., Nikula, K. J., Belinsky, S. A., Barr, E. B., Stoner, G. D., and Lechner, J. F. 1996. Failure of cigarette smoke to induce or promote lung cancer in the A/J mouse. Cancer Lett. 99:161-167.
12. Forkert, P. G., Jackson, A. C., Parkinson, A., and Chen, S. 1996a. Diminished expression of CYP1A1 in urethane-induced lung tumors in strain A/J mice: Analysis by in situ hybridization and immunohistochemical methods. Am. J. Respir. Cell Mol. Biol. 14:444-453.
13. Forkert, P. G., Lord, A. J. A., and Parkinson, A. 1996b. Alterations in expression of CYP1A1 and NADPH-cytochrome P450 reductase during lung tumor development in SWR/J mice. Carcinogenesis 17:127-132.
14. Gebremichael, A., Chiang, A. M., Buckpitt, A. R., Plopper, C. G., and Pinkerton, K. E. 1995. Postnatal development of cytochrome P4501A1 and 2B1 in rat lung and liver: Effect of aged and diluted sidestream cigarette smoke. Toxicol. Appl. Pharmacol. 135:246-253.
15. Gonzalez, F. J., and Gelboin, H. V. 1994. Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins. Drug Metab. Rev. 26:165-183.
16. Guerin, M. R., Jenkins, R. A, and Tomkins, B. A. 1992. The chemistry of environmental tobacco smoke: Composition and measurement. Indoor Air Research Series. Boca Raton, FL: Lewis.
17. Hoffmann, D., Adams, J. D., and Brunnemann, K. D. 1987. A critical look at N-nitrosamines in environmental tobacco smoke. Toxicol. Lett. 35:1-8.
18. Ji, C. M., Plopper, C. G., Witschi, H. P., and Pinkerton, K. E. 1994. Exposure to sidestream cigarette smoke alters bronchiolar epithelial cell differentiation in the postnatal rat lung. Am. J. Respir. Cell. Mol. Biol. 11:312-320.
19. Joad, J. P., Pinkerton, K. E ., and Brie, J. M. 1993. Effects of sidestream smoke exposure and age on pulmonary function and airway reactivity in developing rats. Pediatr. Pulmonol. 16:281-288.
20. Joad, J. P., Bric, J. M., and Pinkerton, K. E. 1995a. Sidestream smoke effects on lung morphology and C-fibers in young guinea pigs. Toxicol. Appl. Pharmacol. 131:289-296.
21. Joad, J. P., Ji, C., Kott, K. S., Brie, J. M., and Pinkerton, K. E. 1995b. In utero and postnatal effects of sidestream cigarette smoke exposure on lung function, hyperresponsiveness, and neuroendocrine cells in rats. Toxicol. Appl. Pharmacol. 132:63-71.
22. Kawamoto, T., Yoshikawa, M., Matsuno, K., Kayama, F., Oyama, T., Arashidani, K., and Kodama, Y. 1993. Effect of side-stream cigarette smoke on the hepatic cytochrome P450. Arch. Environ. Contam. Toxicol. 25:255-259.
23. Lee, C., Peake, J., Chang, A., Buckpitt, A. R., Plopper, C. G., and Pinkerton, K. E. 1996. Site-specific induction of CYP1A1 in developing rat lung by environmental tobacco smoke (ETS). Fundam. Appl. Toxicol. 30(1, Part 2):277.
24. Lee, M. J., and Dinsdale, D. 1995. The subcellular distribution of NADPH-cytochrome P450 reductase and isoenzymes of cytochrome P450 in the lungs of rats and mice. Biochem. Pharmacol. 49:1387-1394.
25. Leuenberger, P., Schwartz, J., Ackermann-Liebrich, U., Blaser, K., Bolognini, G., Bongard, J. P., Brandli, O., Braun, P., Bron, C., and Brutsche, M. 1994. Passive smoking exposure in adults and chronic respiratory symptoms (SAPALDIA Study). Am. J. Respir. Crit. Care Med. 150:1221-1228.
26. Lofroth, C., Burton, R. M., Forehand, L., Hammond, S. K., Seila, R. L., Zweidinger, R. B., and Lewtas, J. 1989. Characterization of environmental tobacco smoke. Environ Sci. Technol 23:610-614.
27. Nagata, K., Martin, B. M., Gillette, J. R., and Sasame, H. A. 1990. Isozymes of cytochrome P-450 that metabolize naphthalene in liver and lung of untreated mice. Drug Metab. Dispos. 18:557-564.
28. National Research Council. 1986. Environmental tobacco smoke. Measuring exposures and assessing health effects. Washington, DC: National Academy Press.
29. Penn, A., Chen, L. C., and Snyder, C. A. 1994. Inhalation of steady-state sidestream smoke from one cigarette promotes arteriosclerotic plaque development. Circulation 90:1363-1367.
30. Plopper, C. G., Suverkropp, C., Morin, D., Nishio, S. and Buckpitt, A. 1992. Relationship of cytochrome P-450 activity to Clara cell cytotoxicity. I. Histopathologic comparison of the respiratory tract of mice, rats and hamsters after parenteral administration of naphthalene. J. Pharmacol. Exp. Ther. 261:353-363.
31. Scherle, W. 1970. A simple method for volumetry of organs in quantitative stereology. Mikroskopie 26:57-60.
32. Schmeltz, I., Tosk, J., and Hoffmann, D. 1976. Formation and determination of naphthalenes in cigarette smoke. Anal. Chem. 48:645-650.
33. Stone, K. C., Mercer, R. R., Gehr, P., Stockstill, B., and Crapo, J. D. 1992. Allometric relationships of cell numbers and size in the mammalian lung. Am. J. Respir. Cell. Mol. Biol. 6:235-243.
34. Teague, S. V., Pinkerton, K. E., Goldsmith, M., Gebremichael, A., Chang, S., Jenkins, R. A., and Moneyhun, J. H. 1994. Sidestream cigarette smoke generation and exposure system for environmental tobacco smoke studies, Inhal. Toxicol. 6:79-93.
35. Tredaniel, J., Boffetta, P., Saracci, R., and Hirsch, A. 1994. Exposure to environmental tobacco smoke and adult non-neoplastic respiratory diseases. Eur. Respir. J 7:173-185.
36. U.S. Environmental Protection Agency. 1992. Respiratory Health Effects of Passive Smoking: Lung Cancer and Other Disorders (EPA/600/6-90/006F). Washington, DC: Office of Health and Environmental Assessment, U.S. EPA.
37. U.S. Surgeon General. 1986. The Health Consequences of Involuntary Smoking. A Report of the Surgeon General. Washington, DC: DHHS (CDC) 87-8398.
38. Villard, P H., Seree, E., and Lacarlogie, Faculte de Pharmacie, Marseille, France. 1994, Effect of cigarette smoke on hepatic and pulmonary cytochromes P450 in mouse: Evidence for CYP2E1 induction in lung. Biochem. Biophys. Res. Commun 202:1731-1737.
39. von Meyerinck, L., Scherer, G., Adlkofer, F., Wenzel-Hartung, R., Brune, H., and Thomas, C. 1989. Exposure of rats and hamsters to sidestream smoke from cigarettes in a subchronic inhalation study. Exp. Pathol. 37:186-189.
40. Weibel, E. R. 1979. Stereological methods. Volume 1: Practical methods for biological morphometry. London: Academic Press.
41. Witschi, H. P., and Rajini, P. 1994. Cell kinetics in the respiratory tract of hamsters exposed to cigarette sidestream smoke, Inhal. Toxicol. 6:321-333.
42. Witschi, H. P., Oreffo, V. I. C., and Pinkerton, K. E. 1995. Six month exposure of strain A/J mice to cigarette sidestream smoke: Cell kinetics and lung tumor data. Fundam. Appl. Toxicol. 26:32-40.