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Volumn 129, Issue 2-3, 1998, Pages 145-156

Localization of cytochrome P4501A1 and covalent binding of a mutagenic heterocyclic amine in blood vessel endothelia of rodents

Author keywords

CYP1A1; Endothelium; Food mutagen; Heart; Immunohistochemistry; Lymph node; Muscle; Uterus

Indexed keywords

CYTOCHROME P450; HETEROCYCLIC AMINE; MUTAGENIC AGENT;

EID: 0032555775     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(98)00087-0     Document Type: Article
Times cited : (23)

References (56)
  • 1
    • 0023154641 scopus 로고
    • Identification of heme oxygenase and cytochrome P450 in the rabbit heart
    • Abraham N.G., Pinto A., Levere R.D., Mullane K. Identification of heme oxygenase and cytochrome P450 in the rabbit heart. J. Mol. Cell. Cardiol. 19:1987;73-81.
    • (1987) J. Mol. Cell. Cardiol. , vol.19 , pp. 73-81
    • Abraham, N.G.1    Pinto, A.2    Levere, R.D.3    Mullane, K.4
  • 2
    • 0022372228 scopus 로고
    • Presence of cytochrome P450-dependent monooxygenase in intimal cells of the hog aorta
    • Abraham N.G., Pinto A., Mullane K.M., Levere R.D., Spokas E. Presence of cytochrome P450-dependent monooxygenase in intimal cells of the hog aorta. Hypertension. 7:1985;899-904.
    • (1985) Hypertension , vol.7 , pp. 899-904
    • Abraham, N.G.1    Pinto, A.2    Mullane, K.M.3    Levere, R.D.4    Spokas, E.5
  • 3
    • 0030788885 scopus 로고    scopus 로고
    • Endothelium-derived hyperpolarizing factor: Characterization as a cytochrome P4501A-linked metabolite of arachidonic acid in perfused rat mesenteric prearteriolar bed
    • Adeagbo A.S. Endothelium-derived hyperpolarizing factor: characterization as a cytochrome P4501A-linked metabolite of arachidonic acid in perfused rat mesenteric prearteriolar bed. Am. J. Hypertens. 10:1997;763-771.
    • (1997) Am. J. Hypertens. , vol.10 , pp. 763-771
    • Adeagbo, A.S.1
  • 4
    • 0023608290 scopus 로고
    • Immunohistochemical determination of inducibility phenotype with a monoclonal antibody to a methylcholanthrene-inducible isozyme of cytochrome P450
    • Anderson L.M., Ward J.M., Park S.S., Jones A.B., Junker J.L., Gelboin H.V., Rice J.M. Immunohistochemical determination of inducibility phenotype with a monoclonal antibody to a methylcholanthrene-inducible isozyme of cytochrome P450. Cancer Res. 47:1987;6079-6085.
    • (1987) Cancer Res. , vol.47 , pp. 6079-6085
    • Anderson, L.M.1    Ward, J.M.2    Park, S.S.3    Jones, A.B.4    Junker, J.L.5    Gelboin, H.V.6    Rice, J.M.7
  • 5
    • 0031838333 scopus 로고    scopus 로고
    • Induction of ethoxyresorufin O-deethylase (EROD) and endothelial activation of the heterocyclic amine Trp-P-1 in bird embryo hearts
    • Annas A., Brunström B., Brandt I., Brittebo E.B. Induction of ethoxyresorufin O-deethylase (EROD) and endothelial activation of the heterocyclic amine Trp-P-1 in bird embryo hearts. Arch. Toxicol. 72:1998;411-419.
    • (1998) Arch. Toxicol. , vol.72 , pp. 411-419
    • Annas, A.1    Brunström, B.2    Brandt, I.3    Brittebo, E.B.4
  • 8
    • 0018805143 scopus 로고
    • Metabolism of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in cultured human fetal aortic smooth muscle cells
    • Bond J.A., Kocan R.M., Benditt E.P., Juchau M.R. Metabolism of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in cultured human fetal aortic smooth muscle cells. Life Sci. 25:1979;425-430.
    • (1979) Life Sci. , vol.25 , pp. 425-430
    • Bond, J.A.1    Kocan, R.M.2    Benditt, E.P.3    Juchau, M.R.4
  • 9
    • 0023130756 scopus 로고
    • Metabolic activation of phenacetin in rat nasal mucosa: Dose dependent binding to the glands of Bowman
    • Brittebo E.B. Metabolic activation of phenacetin in rat nasal mucosa: Dose dependent binding to the glands of Bowman. Cancer Res. 47:1987;1449-1456.
    • (1987) Cancer Res. , vol.47 , pp. 1449-1456
    • Brittebo, E.B.1
  • 10
    • 0028197180 scopus 로고
    • Metabolic activation of the food mutagen Trp-P-1 in endothelial cells of heart and kidney in cytochrome P450-induced mice
    • Brittebo E.B. Metabolic activation of the food mutagen Trp-P-1 in endothelial cells of heart and kidney in cytochrome P450-induced mice. Carcinogenesis. 15:1994;667-672.
    • (1994) Carcinogenesis , vol.15 , pp. 667-672
    • Brittebo, E.B.1
  • 11
    • 0028364375 scopus 로고
    • Metabolic activation of the food mutagen 3-amino-1,4-dimethyl-5H-pyrido-[4,3-b]indole (Trp-P-1) in endothelial cells of cytochrome P450-induced mice
    • Brittebo E.B., Brandt I. Metabolic activation of the food mutagen 3-amino-1,4-dimethyl-5H-pyrido-[4,3-b]indole (Trp-P-1) in endothelial cells of cytochrome P450-induced mice. Cancer Res. 54:1994;2887-2894.
    • (1994) Cancer Res. , vol.54 , pp. 2887-2894
    • Brittebo, E.B.1    Brandt, I.2
  • 12
    • 0030827474 scopus 로고    scopus 로고
    • Cell- And tissue-specific metabolic activation of chemicals as determined by autoradiography. In vivo and in vitro correlations
    • Brittebo E.B., Brandt I. Cell- and tissue-specific metabolic activation of chemicals as determined by autoradiography. In vivo and in vitro correlations. Toxicol. In Vitro. 11:1997;417-426.
    • (1997) Toxicol. in Vitro , vol.11 , pp. 417-426
    • Brittebo, E.B.1    Brandt, I.2
  • 13
    • 17744417304 scopus 로고    scopus 로고
    • Glucocorticoid potentiation of cytochrome P4501A1 induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin in porcine and human endothelial cells in culture
    • Celander M., Weisbrod R., Stegeman J.J. Glucocorticoid potentiation of cytochrome P4501A1 induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin in porcine and human endothelial cells in culture. Biochem. Biophys. Res. Commun. 232:1997;749-753.
    • (1997) Biochem. Biophys. Res. Commun. , vol.232 , pp. 749-753
    • Celander, M.1    Weisbrod, R.2    Stegeman, J.J.3
  • 14
    • 0029794001 scopus 로고    scopus 로고
    • Modulation of endothelium-dependent hyperpolarization and relaxation to acetylcholine in rat mesenteric artery by cytochrome P450 enzyme activity
    • Chen G., Cheung D.W. Modulation of endothelium-dependent hyperpolarization and relaxation to acetylcholine in rat mesenteric artery by cytochrome P450 enzyme activity. Circ. Res. 79:1996;827-833.
    • (1996) Circ. Res. , vol.79 , pp. 827-833
    • Chen, G.1    Cheung, D.W.2
  • 15
    • 0028334140 scopus 로고
    • Cytochrome P450 during ontogenic development: Occurence in the ductus arteiosus and other tissues
    • Coceani F., Kelsey L., Ackerley C., Rabinovitch M., Gelboin H. Cytochrome P450 during ontogenic development: occurence in the ductus arteiosus and other tissues. Can. J. Physiol. Pharmacol. 72:1994;217-226.
    • (1994) Can. J. Physiol. Pharmacol. , vol.72 , pp. 217-226
    • Coceani, F.1    Kelsey, L.2    Ackerley, C.3    Rabinovitch, M.4    Gelboin, H.5
  • 16
    • 0030973973 scopus 로고    scopus 로고
    • An investigation into the role of rat skeletal muscle as a site for xenobiotic metabolism using microsomes and isolated cells
    • Crosbie S.J., Blain P.G., Williams F.M. An investigation into the role of rat skeletal muscle as a site for xenobiotic metabolism using microsomes and isolated cells. Hum. Exp. Toxicol. 16:1997;138-145.
    • (1997) Hum. Exp. Toxicol. , vol.16 , pp. 138-145
    • Crosbie, S.J.1    Blain, P.G.2    Williams, F.M.3
  • 17
    • 0028798307 scopus 로고
    • Short synthetic peptides exploited for reliable and specific targeting of antibodies to the C-termini of cytochrome P450 enzymes
    • Edwards R.J., Singleton A.M., Murray B.P., Davies D.S., Boobis A.R. Short synthetic peptides exploited for reliable and specific targeting of antibodies to the C-termini of cytochrome P450 enzymes. Biochem. Pharmacol. 49:1995;39-47.
    • (1995) Biochem. Pharmacol. , vol.49 , pp. 39-47
    • Edwards, R.J.1    Singleton, A.M.2    Murray, B.P.3    Davies, D.S.4    Boobis, A.R.5
  • 19
    • 0028230708 scopus 로고
    • Expression of cytochrome P450s and microsomal epoxide hydrolase in primary cultures of human umbilical vein endothelial cells
    • Farin F.M., Pohlman T.H., Omiecinski C.J. Expression of cytochrome P450s and microsomal epoxide hydrolase in primary cultures of human umbilical vein endothelial cells. Toxicol. Appl. Pharmacol. 124:1994;1-9.
    • (1994) Toxicol. Appl. Pharmacol. , vol.124 , pp. 1-9
    • Farin, F.M.1    Pohlman, T.H.2    Omiecinski, C.J.3
  • 21
    • 0029985411 scopus 로고    scopus 로고
    • Alterations in expression of CYP1A1 and NADPH-cytochrome P450 reductase during lung tumor development in SWR/J mice
    • Forkert P.G., Lord J.A., Parkinson A. Alterations in expression of CYP1A1 and NADPH-cytochrome P450 reductase during lung tumor development in SWR/J mice. Carcinogenesis. 17:1996;127-132.
    • (1996) Carcinogenesis , vol.17 , pp. 127-132
    • Forkert, P.G.1    Lord, J.A.2    Parkinson, A.3
  • 22
    • 0024317866 scopus 로고
    • Cytochromes P450 in murine lung. An immunohistochemical study with monoclonal antibodies
    • Forkert P.G., Vessey M.L., Park S.S., Gelboin H.V., Cole S.P. Cytochromes P450 in murine lung. An immunohistochemical study with monoclonal antibodies. Drug. Metab. Dispos. 17:1989;551-555.
    • (1989) Drug. Metab. Dispos. , vol.17 , pp. 551-555
    • Forkert, P.G.1    Vessey, M.L.2    Park, S.S.3    Gelboin, H.V.4    Cole, S.P.5
  • 23
    • 0022872207 scopus 로고
    • Immunocytochemical localization of cytochrome P450 in hepatic and extra-hepatic tissues of the rat with a monoclonal antibody against cytochrome P450c
    • Foster J.R., Elcombe C.R., Boobis A.R., Davies D.S., Sesardic D., McQuade J., Robson R.T., Hayward C., Lock E.A. Immunocytochemical localization of cytochrome P450 in hepatic and extra-hepatic tissues of the rat with a monoclonal antibody against cytochrome P450c. Biochem. Pharmacol. 35:1986;4543-4554.
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 4543-4554
    • Foster, J.R.1    Elcombe, C.R.2    Boobis, A.R.3    Davies, D.S.4    Sesardic, D.5    McQuade, J.6    Robson, R.T.7    Hayward, C.8    Lock, E.A.9
  • 24
    • 0031017779 scopus 로고    scopus 로고
    • Evidence against a role of cytochrome P450-derived arachidonic acid metabolites in endothelium-dependent hyperpolarization by acetylcholine in rat mesenteric artery
    • Fukao M., Hattori Y., Kanno M., Sakuma I., Kitabatake A. Evidence against a role of cytochrome P450-derived arachidonic acid metabolites in endothelium-dependent hyperpolarization by acetylcholine in rat mesenteric artery. Br. J. Pharmacol. 120:1997;439-446.
    • (1997) Br. J. Pharmacol. , vol.120 , pp. 439-446
    • Fukao, M.1    Hattori, Y.2    Kanno, M.3    Sakuma, I.4    Kitabatake, A.5
  • 25
    • 0028959189 scopus 로고
    • Cytochrome P450-dependent effects of bradykinin in the rat heart
    • Fulton D., Mahboubi K., McGiff J.C., Quilley J. Cytochrome P450-dependent effects of bradykinin in the rat heart. Br. J. Pharmacol. 114:1995;99-102.
    • (1995) Br. J. Pharmacol , vol.114 , pp. 99-102
    • Fulton, D.1    Mahboubi, K.2    McGiff, J.C.3    Quilley, J.4
  • 27
    • 0025854668 scopus 로고
    • Developmentally regulated cytochrome P4501A1 expression in cultured rat vascular smooth muscle cells
    • Giachelli C.M., Majesky M.W., Schwartz S.M. Developmentally regulated cytochrome P4501A1 expression in cultured rat vascular smooth muscle cells. J. Biol. Chem. 266:1991;3981-3986.
    • (1991) J. Biol. Chem. , vol.266 , pp. 3981-3986
    • Giachelli, C.M.1    Majesky, M.W.2    Schwartz, S.M.3
  • 28
    • 0025823398 scopus 로고
    • Great Lakes embryo mortality, edema, and deformities syndrome (GLEMEDS) in colonial fish-eating birds: Similarity to chick-edema disease
    • Gilbertson M., Kubiak T., Ludwig J., Fox G. Great Lakes embryo mortality, edema, and deformities syndrome (GLEMEDS) in colonial fish-eating birds: Similarity to chick-edema disease. J. Toxicol. Environ. Health. 33:1991;455-520.
    • (1991) J. Toxicol. Environ. Health , vol.33 , pp. 455-520
    • Gilbertson, M.1    Kubiak, T.2    Ludwig, J.3    Fox, G.4
  • 29
    • 0018310411 scopus 로고
    • Immunological comparison of hepatic and extrahepatic cytochromes P450
    • Guengerich F.P., Mason P.S. Immunological comparison of hepatic and extrahepatic cytochromes P450. Mol. Pharmacol. 15:1979;154-164.
    • (1979) Mol. Pharmacol. , vol.15 , pp. 154-164
    • Guengerich, F.P.1    Mason, P.S.2
  • 30
    • 0030995904 scopus 로고    scopus 로고
    • Correlation of 2,3,7,8-tetrachlorodibenzo-p-dioxin induction of cytochrome P4501A in vascular endothelium with toxicity in early life stages of lake trout
    • Guiney P.D., Smolowitz R.M., Peterson R.E., Stegeman J.J. Correlation of 2,3,7,8-tetrachlorodibenzo-p-dioxin induction of cytochrome P4501A in vascular endothelium with toxicity in early life stages of lake trout. Toxicol. Appl. Pharmacol. 143:1997;256-273.
    • (1997) Toxicol. Appl. Pharmacol. , vol.143 , pp. 256-273
    • Guiney, P.D.1    Smolowitz, R.M.2    Peterson, R.E.3    Stegeman, J.J.4
  • 31
    • 0028802649 scopus 로고
    • Sheep lung cytochrome P4501A1 (CYP1A1): CDNA cloning and transcriptional regulation by oxygen tension
    • Hazinski T.A., Noisin E., Hamon I., De Matteo A. Sheep lung cytochrome P4501A1 (CYP1A1): cDNA cloning and transcriptional regulation by oxygen tension. J. Clin. Invest. 96:1995;2083-2089.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2083-2089
    • Hazinski, T.A.1    Noisin, E.2    Hamon, I.3    De Matteo, A.4
  • 33
    • 0027946666 scopus 로고
    • Immunohistochemical localization of CYP1A and CYP3A-like isozymes in hepatic and extrahepatic tissues of atlantic cod (Gadus morhua L.), a marine fish
    • Husøy A.M., Myers M.S., Willis M.L., Collier T.K., Celander M., Goksøyr A. Immunohistochemical localization of CYP1A and CYP3A-like isozymes in hepatic and extrahepatic tissues of atlantic cod (Gadus morhua L.), a marine fish. Toxicol. Appl. Pharmacol. 129:1994;294-308.
    • (1994) Toxicol. Appl. Pharmacol. , vol.129 , pp. 294-308
    • Husøy, A.M.1    Myers, M.S.2    Willis, M.L.3    Collier, T.K.4    Celander, M.5    Goksøyr, A.6
  • 34
    • 0347600814 scopus 로고
    • Aryl 4-monooxygenase and cytochrome P450 in the aorta: Possible role in atherosclerosis
    • Juchau M.R., Bond J.A., Benditt E.P. Aryl 4-monooxygenase and cytochrome P450 in the aorta: possible role in atherosclerosis. Proc. Natl. Acad. Sci. USA. 73:1976;3723-3725.
    • (1976) Proc. Natl. Acad. Sci. USA , vol.73 , pp. 3723-3725
    • Juchau, M.R.1    Bond, J.A.2    Benditt, E.P.3
  • 35
    • 0023115083 scopus 로고
    • Immunological identification and effects of 3-methylcholanthrene and phenobarbital on rat pulmonary cytochrome P450
    • Keith I.M., Olson Jr E.B., Wilson N.M., Jefcoate C.R. Immunological identification and effects of 3-methylcholanthrene and phenobarbital on rat pulmonary cytochrome P450. Cancer. Res. 47:1987;1878-1882.
    • (1987) Cancer. Res. , vol.47 , pp. 1878-1882
    • Keith, I.M.1    Olson Jr, E.B.2    Wilson, N.M.3    Jefcoate, C.R.4
  • 36
    • 0027791631 scopus 로고
    • Cytochrome P450 1A1 cDNA from plaice (Pleuronectes platessa) and induction of P4501A1 mRNA in various tissues by 3-methylcholantrene and isosafrole
    • Leaver M.J., Pirrit L., George S.G. Cytochrome P450 1A1 cDNA from plaice (Pleuronectes platessa) and induction of P4501A1 mRNA in various tissues by 3-methylcholantrene and isosafrole. Mol. Marine Biol. Biotechnol. 2:1993;338-345.
    • (1993) Mol. Marine Biol. Biotechnol. , vol.2 , pp. 338-345
    • Leaver, M.J.1    Pirrit, L.2    George, S.G.3
  • 37
    • 0025768619 scopus 로고
    • Carcinogenic tryptophan pyrolysis products in the environment
    • Manabe S., Wada O. Carcinogenic tryptophan pyrolysis products in the environment. J. Toxicol. Sci. Suppl. 1:1991;63-72.
    • (1991) J. Toxicol. Sci. Suppl. , vol.1 , pp. 63-72
    • Manabe, S.1    Wada, O.2
  • 38
    • 0027272647 scopus 로고
    • Microsomal cytochrome P4501A1 dependent monooxygenase activity in guinea pig heart: Induction, inhibition, and increased activity by addition of exogenous NADPH-cytochrome P450 reductase
    • McCallum G.P., Horton J.E., Falkner K.C., Bend J.R. Microsomal cytochrome P4501A1 dependent monooxygenase activity in guinea pig heart: induction, inhibition, and increased activity by addition of exogenous NADPH-cytochrome P450 reductase. Can. J. Physiol. Pharmacol. 71:1993;151-156.
    • (1993) Can. J. Physiol. Pharmacol. , vol.71 , pp. 151-156
    • McCallum, G.P.1    Horton, J.E.2    Falkner, K.C.3    Bend, J.R.4
  • 39
    • 0027085797 scopus 로고
    • Distribution of cytochrome P450 1A1 and NADPH-cytochrome P450 reductase in lungs of rabbits treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin: Ultrastructural immunolocalization and in situ hybridization
    • Overby L.H., Nishio S., Weir A., Carver G.T., Plopper C.G., Philpot R.M. Distribution of cytochrome P450 1A1 and NADPH-cytochrome P450 reductase in lungs of rabbits treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin: Ultrastructural immunolocalization and in situ hybridization. Mol. Pharmacol. 41:1992;1039-1046.
    • (1992) Mol. Pharmacol. , vol.41 , pp. 1039-1046
    • Overby, L.H.1    Nishio, S.2    Weir, A.3    Carver, G.T.4    Plopper, C.G.5    Philpot, R.M.6
  • 40
    • 0026068899 scopus 로고
    • Cytochrome P450-dependent vasodilator responses to arachidonic acid in the isolated, perfused kidney of the rat
    • Oyekan A.O., McGiff J.C., Quilley J. Cytochrome P450-dependent vasodilator responses to arachidonic acid in the isolated, perfused kidney of the rat. Circ. Res. 68:1991;958-965.
    • (1991) Circ. Res. , vol.68 , pp. 958-965
    • Oyekan, A.O.1    McGiff, J.C.2    Quilley, J.3
  • 42
    • 0030471649 scopus 로고    scopus 로고
    • Quantitative histology and cytochrome P450 immunocytochemistry of the lung parenchyma following 6 months of exposure strain A/J mice to cigarette sidestream smoke
    • Pinkerton K.E., Peake J.L., Espiritu I., Goldsmith M., Witschi H. Quantitative histology and cytochrome P450 immunocytochemistry of the lung parenchyma following 6 months of exposure strain A/J mice to cigarette sidestream smoke. Inhal. Toxicol. 8:1996;927-945.
    • (1996) Inhal. Toxicol. , vol.8 , pp. 927-945
    • Pinkerton, K.E.1    Peake, J.L.2    Espiritu, I.3    Goldsmith, M.4    Witschi, H.5
  • 43
    • 0022643368 scopus 로고
    • Cytochrome P450-dependent monooxygenase activity and endothelial-dependent relaxations induced by arachidonic acid
    • Pinto A., Abraham A.G., Mullane K.M. Cytochrome P450-dependent monooxygenase activity and endothelial-dependent relaxations induced by arachidonic acid. J. Pharmacol. Exp. Ther. 236:1986;445-451.
    • (1986) J. Pharmacol. Exp. Ther. , vol.236 , pp. 445-451
    • Pinto, A.1    Abraham, A.G.2    Mullane, K.M.3
  • 44
    • 0030481562 scopus 로고    scopus 로고
    • A transferable, beta naphthoflavone inducible, hyperpolarizing factor is synthesized by native and cultured porcine coronary endothelial cells
    • Popp R., Bauersachs J., Hecker M., Fleming I., Busse R. A transferable, beta naphthoflavone inducible, hyperpolarizing factor is synthesized by native and cultured porcine coronary endothelial cells. J. Physiol. 497:1996;699-709.
    • (1996) J. Physiol. , vol.497 , pp. 699-709
    • Popp, R.1    Bauersachs, J.2    Hecker, M.3    Fleming, I.4    Busse, R.5
  • 45
    • 0028055135 scopus 로고
    • Aryl hydrocarbon hydroxylase activity in chemically induced and toremifene-treated mammary tumors in rats
    • Pyykkö K., Ala-Uotila S., Jaakola U.M., Lähde M. Aryl hydrocarbon hydroxylase activity in chemically induced and toremifene-treated mammary tumors in rats. Int. J. Cancer. 56:1994;140-145.
    • (1994) Int. J. Cancer , vol.56 , pp. 140-145
    • Pyykkö, K.1    Ala-Uotila, S.2    Jaakola, U.M.3    Lähde, M.4
  • 46
    • 0020619294 scopus 로고
    • Benoxaprofen suppression of polychlorinated biphenyl toxicity without alteration of mixed function oxidase function
    • Rifkind A.B., Muschick H. Benoxaprofen suppression of polychlorinated biphenyl toxicity without alteration of mixed function oxidase function. Nature. 303:1983;524-526.
    • (1983) Nature , vol.303 , pp. 524-526
    • Rifkind, A.B.1    Muschick, H.2
  • 47
    • 0021860557 scopus 로고
    • Cytochrome P450 monooxygenase system. Localization in smooth muscle of rabbit aorta
    • Serabjit-Singh C.J., Bend J.R., Philpot R.M. Cytochrome P450 monooxygenase system. Localization in smooth muscle of rabbit aorta. Mol. Pharmacol. 28:1985;72-79.
    • (1985) Mol. Pharmacol. , vol.28 , pp. 72-79
    • Serabjit-Singh, C.J.1    Bend, J.R.2    Philpot, R.M.3
  • 49
    • 0030006119 scopus 로고    scopus 로고
    • Characterization of microsomal cytochrome P450 enzymes involved in the oxidation of xenobiotic chemicals in human fetal liver and adult lungs
    • Shimada T., Yamazaki H., Mimura M., Wakamiya N., Ueng Y.F., Guengerich F.P., Inui Y. Characterization of microsomal cytochrome P450 enzymes involved in the oxidation of xenobiotic chemicals in human fetal liver and adult lungs. Drug. Metab. Dispos. 24:1996;515-522.
    • (1996) Drug. Metab. Dispos. , vol.24 , pp. 515-522
    • Shimada, T.1    Yamazaki, H.2    Mimura, M.3    Wakamiya, N.4    Ueng, Y.F.5    Guengerich, F.P.6    Inui, Y.7
  • 50
    • 0027077438 scopus 로고
    • Characterization of human lung microsomal cytochrome P4501A1 and its role in oxidation of chemical carcinogens
    • Shimada T., Yun C.H., Yamazaki H., Gautier J.C., Beaune P.H., Guengerich F.P. Characterization of human lung microsomal cytochrome P4501A1 and its role in oxidation of chemical carcinogens. Mol. Pharmacol. 41:1992;856-864.
    • (1992) Mol. Pharmacol. , vol.41 , pp. 856-864
    • Shimada, T.1    Yun, C.H.2    Yamazaki, H.3    Gautier, J.C.4    Beaune, P.H.5    Guengerich, F.P.6
  • 51
    • 0027093870 scopus 로고
    • Cytochrome P4501A induction in tissues, including olfactory epithelium, of topminnows (Poeciliopsis spp.) by waterborne benzo[a]pyrene
    • Smolowitz R.M., Schultz M.E., Stegeman J.J. Cytochrome P4501A induction in tissues, including olfactory epithelium, of topminnows (Poeciliopsis spp.) by waterborne benzo[a]pyrene. Carcinogenesis. 13:1992;2395-2402.
    • (1992) Carcinogenesis , vol.13 , pp. 2395-2402
    • Smolowitz, R.M.1    Schultz, M.E.2    Stegeman, J.J.3
  • 52
    • 0028953763 scopus 로고
    • Induction of cytochrome P4501A1 by aryl hydrocarbon receptor agonists in porcine aorta endothelial cells in culture and cytochrome P4501A1 activity in intact cells
    • Stegeman J.J., Hahn M.E., Weisbrod R., Woodin B.R., Joy J.S., Najibi S., Cohen R.A. Induction of cytochrome P4501A1 by aryl hydrocarbon receptor agonists in porcine aorta endothelial cells in culture and cytochrome P4501A1 activity in intact cells. Mol. Pharmacol. 47:1995;296-306.
    • (1995) Mol. Pharmacol. , vol.47 , pp. 296-306
    • Stegeman, J.J.1    Hahn, M.E.2    Weisbrod, R.3    Woodin, B.R.4    Joy, J.S.5    Najibi, S.6    Cohen, R.A.7
  • 53
    • 0024331916 scopus 로고
    • Cytochrome P4501A1 induction and localization in endothelium of vertebrate (teleost) heart
    • Stegeman J.J., Miller M.R., Hinton D.E. Cytochrome P4501A1 induction and localization in endothelium of vertebrate (teleost) heart. Mol. Pharmacol. 36:1989;723-729.
    • (1989) Mol. Pharmacol. , vol.36 , pp. 723-729
    • Stegeman, J.J.1    Miller, M.R.2    Hinton, D.E.3
  • 54
    • 0026059145 scopus 로고
    • Immunohistochemical localization of environmentally induced cytochrome P4501A1 in multiple organs of the marine teleost Stenotomus chrysops (Scup)
    • Stegeman J.J., Smolowitz R.M., Hahn M.E. Immunohistochemical localization of environmentally induced cytochrome P4501A1 in multiple organs of the marine teleost Stenotomus chrysops (Scup). Toxicol. Appl. Pharmacol. 110:1991;486-504.
    • (1991) Toxicol. Appl. Pharmacol. , vol.110 , pp. 486-504
    • Stegeman, J.J.1    Smolowitz, R.M.2    Hahn, M.E.3
  • 55
    • 0022007203 scopus 로고
    • Carcinogenicity of mutagenic heterocyclic amines formed during the cooking process
    • Sugimura T. Carcinogenicity of mutagenic heterocyclic amines formed during the cooking process. Mut. Res. 150:1985;33-41.
    • (1985) Mut. Res. , vol.150 , pp. 33-41
    • Sugimura, T.1
  • 56
    • 0030913808 scopus 로고    scopus 로고
    • Evidence against the involvement of cytochrome P450 metabolites in endothelium-dependent hyperpolarization of the rat main mesenteric artery
    • Vanheel B., Van de Voorde J. Evidence against the involvement of cytochrome P450 metabolites in endothelium-dependent hyperpolarization of the rat main mesenteric artery. J. Physiol. Lond. 501:1997;331-341.
    • (1997) J. Physiol. Lond. , vol.501 , pp. 331-341
    • Vanheel, B.1    Van De Voorde, J.2


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