Thiol-disulfide isomerization in thrombospondin: Effects of conformation and protein disulfide isomerase

Blood

Volumn 89, Issue 9, 1997, Pages 3205-3212

  Huang, Evelyn M ^a   Detwiler, Thomas C ^a   Milev, Youli ^a   Essex, David W ^a,b  

^a STATE UNIVERSITY OF NEW YORK   (United States)

^b SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISULFIDE; PROTEIN DISULFIDE ISOMERASE; THIOL DERIVATIVE; THROMBOSPONDIN;

ANTIBODY SPECIFICITY; ARTICLE; CONFORMATIONAL TRANSITION; DISULFIDE BOND; DRUG EFFECT; ENDOPLASMIC RETICULUM; EXTRACELLULAR MATRIX; FIBRINOLYSIS; FLOW CYTOMETRY; HEMOSTASIS; HUMAN; HUMAN CELL; IMMUNOASSAY; ISOMERISM; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN CONFORMATION;

EID: 0030904864     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v89.9.3205     Document Type: Article

References (25)

1. Frazier W: Structure and function of thrombospondin. Trends Glycosci & Glycotechnol 4:152, 1992
2. Mumby EJ, Raugi GJ, Bornstein P: Interactions of thrombospondin with extracellular matrix proteins. J Cell Biol 98:646, 1984
3. Galvin NJ, Vance PM, Dixit VM, Fink B, Frazier WA: Interaction of human thrombospondin with types I-V collagen: Direct binding and electron microscopy. J Cell Biol 104:1413, 1987
4. Hogg PJ, Owensby DA, Chesterman CN: Thrombospondin 1 is a tight-binding competitive inhibitor of neutrophil cathepsin G. J Biol Chem 268:21811, 1993
5. Hogg PJ, Jimenez BM, Stathakis P, Chesterman CN: Platelet-derived growth factor binds tightly and specifically to thrombospondin 1. Thromb Haemost 73:964a, 1995
6. Misenheimer TM, Mosher DF: Calcium binding to thrombospondin 1. J Biol Chem 270:1729, 1995
7. Danishefsky KJ, Alexander RJ, Detwiler TC: Formation of a stable complex of thrombin and the secreted platelet glycoprotein G (thrombin-sensitive protein, thrombospondin) by thiol-disulfide exchange. Biochemistry 23:4984, 1984
8. Miller JJ, Browne PC, Detwiler TC: Complexes of thrombin with secreted platelet proteins. Biochem Biophys Res Commun 151:9, 1988
9. Detwiler TC, Chang AC, Speziale MV, Browne PC, Miller JJ, Chen K: Complexes of thrombin with proteins secreted by activated platelets. Semin Thromb Hemost 18:60, 1992
10. Speziale MV, Detwiler TC: Free thiols of platelet thrombospondin. Evidence for disulfide isomerization. J Biol Chem 265:17859, 1990
11. Sun X, Skorstengaard K, Mosher DF: Disulfides modulate RGD-inhibitable cell adhesive activity of thrombospondin. J Cell Biol 118:693, 1992
12. Essex DW, Chen K, Swiatkowska M: Localization of protein disulfide isomerase to the external surface of the platelet plasma membrane, Blood 86:2168, 1995
13. Chen K, Detwiler TC, Essex DW: Characterization of protein disulfide isomerase released from activated platelets. Br J Haematol 425, 1995
14. Chen K, Lin Y, Detwiler TC: Protein disulfide isomerase activity is released by activated platelets. Blood 79:2226, 1992
15. Dixit VM, Galvin NJ, O'Rourke KM, Frazier WA: Monoclonal antibodies that recognize calcium-dependent structures of human thrombospondin. J Biol Chem 261:1962, 1986
16. Hillson DA, Lambert N, Freedman RB: Formation and isomerization of disulfide bonds in proteins: Protein disulfide isomerase. Methods Enzymol 107:281, 1984
17. Lawler J, Derick LH, Connolly JE, Chen JH, Chao FC: The structure of human platelet thrombospondin. J Biol Chem 260:3762, 1985
18. Lawler J, Simons ER: Cooperative binding of calcium to thrombospondin. J Biol Chem 258:12098, 1983
19. Dixit VM, Haverstick DM, O'Rourke KM, Hennessy SW, Grant GA, Santoro SA, Frazier WA: A monoclonal antibody against human thrombospondin inhibits platelet aggregation. Proc Natl Acad Sci USA 82:3472, 1985
20. Lawler J, Weinstein R, Hynes RO: Cell attachment to throiribospondin: The role of Arg-Gly-Asp, calcium and integrin receptors. J Cell Biol 107:2351, 1988
21. Narasimhan C, Lai CS, Haas A, McCarthy J: One free sulfhydryl group of plasma fibronectin becomes titratable upon binding of the protein to solid substrates. J Biochem 27:4970, 1988
22. Ugarova TP, Budzynski AZ, Shattil SJ, Rugged ZM, Ginsberg MH, Plow EF: Conformational changes in fibrinogen elicited by its interaction with platelet membrane glycoprotein GPIIb-IIIa. J Biol Chem 268:21060, 1993
23. Leung LLK, L WX, McGregor JL, Alberecht G, Howard RJ: CD36 peptides enhance or inhibit CD36-thrombospondin bindings: A two-step process of ligand-receptor interaction. J Biol Chem 267:18244, 1992
24. Hogg PJ, Owensby DA, Mosher DF, Misenheimer TM, Chesterman CN: Thrombospondin is a tight-binding competitive inhibitor of neutrophil elastase. J Biol Chem 268:7139, 1993
25. Hogg PJ: Thrombospondin 1 as an enzyme inhibitor. Thromb Haemost 72:787, 1994