Enhanced aggregation of human neutrophils by MnCl2 or DTT differentiates the roles of L-selectin and β2-integrins

Journal of Leukocyte Biology

Volumn 60, Issue 3, 1996, Pages 356-364

  Lynam, Eric B ^a   Rogelj, Snezna ^a   Edwards, Bruce S ^b   Sklar, Larry A ^a,c  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^b LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^c LOS ALAMOS NATIONAL LABORATORY   (United States)

Author keywords

DREG200; Flow cytometry; IB4; PMN adhesion

Indexed keywords

DITHIOTHREITOL; FORMYLPEPTIDE; INTEGRIN; L SELECTIN; MANGANESE CHLORIDE;

ARTICLE; CELL AGGREGATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; NEUTROPHIL; PRIORITY JOURNAL;

EID: 0029792214     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.60.3.356     Document Type: Article

References (35)

1. O'Flaherty, J. T., Kreutzer, D. L., Ward, P. A. (1977) Neutrophil aggregation and swelling induced by chemotactic agents. J. Immunol. 119, 232-239.
2. Kuijpers, T. W., Koenderman, L., Weening, R. S., Verhoeven, A. J., Roos, D. (1990) Continuous cell activation is necessary for stable interaction of complement receptor type 3 with its counter-structure in the aggregation response of human neutrophils. Eur. J. Immunol. 20, 501-508.
3. Simon, S. I., Chambers, J. D., Sklar, L. A. (1990) Flow cytometric analysis and modeling of cell-cell adhesive interactions: the neutrophil as a model. J. Cell Biol. 111, 2747-2756.
4. 2-integrin and L-selectin-dependent in blood and isolated cells. J. Immunol. 149, 2765-2771.
5. 2-integrin and L-selectin are obligatory receptors in neutrophil aggregation. Blood 82, 1097-1106.
6. Guyer, D.G., Moore, K.L., Lynam, E.B., Schammel, C.M.G., Rogelj, S., McEver, R.P., Sklar, L.A. (1996) P-selectin glycoprotein ligand-1 (PSGL-1) is a ligand for L-selectin in neutrophil aggregation. Blood In press.
7. Bennett, T. A., Schammel, C. M. G., Lynam, E. B., Guyer, D. A., Mellors, A., Edwards, B., Rogelj, S., Sklar, L. A. (1995) Evidence for a third component in neutrophil aggregation: potential roles of O-linked glycoproteins as L-selectin counter-structures. J. Leukoc. Biol. 58, 510-518.
8. O'Flaherty, J. T., Showell, H. J., Becker, E. L., Ward, P. A. (1978) Substances which aggregate neutrophils. Mechanism of action. Am. J. Pathol. 92, 155-166.
9. Corbi, A. L., Kishimoto, T. K., Miller, L. J., Springer, T. A. (1988) The human leukocyte adhesion glycoprotein Mac-1 (complement receptor type 3, CD11b) alpha subunits; cloning, primary structure, and relation to the integrins, von Willebrand factor, and factor B. J. Biol. Chem. 263, 12403-12411.
10. Arnaout, M. A., Gupta, S. K., Pierce, M. W., Tenen, D. G. (1988) Amino acid sequence of the alpha subunit of human leukocyte adhesion receptor Mo-1 (complement receptor type 3). J. Cell. Biol. 106, 2153-2158.
11. Graham, I. L., Brown, E. J. (1991) Extracellular calcium results in a conformational change in Mac-1 (CD11b/CD18) on neutrophils: differentiation of adhesion and phagocytosis functions of Mac-1. J. Immunol. 146, 685-691.
12. Altieri, D. C. (1991) Occupancy of CD11b/CD18 (Mac-1) divalent ion binding site(s) induces leukocyte adhesion. J. Immunol. 147, 1891-1898.
13. Davis, G. E., Camarillo, C. W. (1993) Regulation of integrin mediated myeloid cell adhesion to fibronectin: influence of disulfide reducing agents, divalent cations, and phorbol ester. J. Immunol. 151, 7138-7150.
14. Kishimoto, T. K., Jutila, M. A., Berg, E. L., Butcher, E. C. (1989) Neutrophil Mac-1 and MEL-14 adhesion proteins inversely regulated by chemotactic factors. Science 245, 1238-1241.
15. Altieri, D. C., Edgington, T. S. (1988) A monoclonal antibody reacting with distinct adhesion molecules defines a transition in the functional state of the receptor CD11b/CD18 (Mac-1). J. Immunol. 141, 2656-2660.
16. Dransfield, I., Cabañas, C., Barrett, J., Hogg, N. (1992) Interaction of leukocyte integrin with ligand is necessary but not sufficient for function. J. Cell Biol. 116, 1527-1535.
17. Landis., R. C., Bennett, R. J., Hogg, N. (1993) A novel LFA-1 activation epitope maps to the I domain. J. Cell. Biol. 120, 1519-1527.
18. Diamond, M. S., Springer, T. A. (1993) A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen. J. Cell Biol. 120, 545-556.
19. Robinson, M. K., Andrew, D., Rosen, H., Brown, D., Ortlepp, S., Stephens, P., Butcher, E. C. (1992) Antibody against the LEU-CAM β chain (CD18) promotes both LFA-1 and CR3 dependent adhesion events. J. Immunol. 148, 1080-1085.
20. Andrew, D., Shock, A., Ball, E., Ortlepp, S., Bell, J., Robinson, M. (1993) Kim-185, a monoclonal antibody to CD18 which induces a change in the conformation of CD18 and promotes both LFA-1- and CR3-dependent adhesion. Eur. J. Immunol. 23, 2217-2222.
21. Schwartz, B. R., Harlan, J. M. (1989) Sulfhydryl reducing agents promote neutrophil adherence without increasing surface expression of CD11b/CD18 (Mac-1, Mo-1). Biochem. Biophys. Res. Commun. 165, 51-57.
22. Cleland, W. W. (1963) Dithiothreitol, a new protective reagent for SH groups. Biochem. 3, 480-486.
23. Carlos, T. M., Harlan, J. M. (1990) Membrane proteins involved in phagocyte adherence to endothelium. Immunol. Rev. 114, 5-28.
24. Edwards, B. S., Curry, M. S., Southon, E. A., Chong, A. S. F, Graf, L. H. (1995) Evidence for a dithiol-activated signaling pathway in natural killer cell avidity regulation of leukocyte function antigen-1: structural requirements and relationship to phorbol ester- and CD16-triggered pathways. Blood 86, 2288-2301.
25. Kishimoto, T. K., O'Connor, K., Lee, A., Roberts, T. M., Springer, T. A. (1987) Cloning of the beta subunit of the leukocyte adhesion proteins: homology to an extracellular matrix receptor defines a novel supergene family. Cell 60, 755-765.
26. Terstappen, L. W., Loken, M. R. (1988) Five dimensional flow cytometry as a new approach for blood and bone marrow differentials. Cytometry 9, 548-556.
27. Lynam, E. B., Simon, S. I., Rochon, Y. P., Sklar, L. A. (1994) Lipopolysaccharide enhances CD11b/CD18 function but inhibits neutrophil aggregation. Blood 83, 3303-3311.
28. Baggiolini, M., Boulay, F., Badwey, J. A., Curnutte, J. T. (1993) Activation of neutrophil leukocytes: chemoattractant receptors and respiratory burst. FASEB J. 7, 1004-1010.
29. Wright, S. A., Ramos, R. A., Hermanowski-Vosatka, A., Rockwell, P., Detmers, P. A. (1991) Activation of the adhesive capacity of CR3 on neutrophils by endotoxin: dependence on LBP and CD14. J. Exp. Med. 173, 1281-1286.
30. Bennet, T. A., Lynam, E. B., Sklar, L. A., Rogelj, S. (1996) A hydroxamate-based metalloprotease inhibitor blocks the shedding of the L-selectin adhesion molecule from leukocytes: functional consequences for neutrophil aggregation. J. Immunol. 156, 3093-3097.
31. 2-integrins in vivo. Proc. Natl. Acad. Sci. USA 88, 7538-7542.
32. Butcher, E. C. (1991) Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 67, 1033-1036.
33. Springer, T. A. (1994) Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76, 301-314.
34. 2-integrins by stimulated human neutrophils analyzed by flow cytometry. J. Leukoc. Biol. 53, 462-469.
35. Hughes, B. J., Hollers, J. C., Crockett-Torabi, E., Smith, C. W. (1992) Recruitment of CD11b/CD18 to the neutrophil surface and adhesion dependent cell locomotion. J. Clin. Invest. 90, 1687-1696.