Differential expression of glutamate receptor subtypes in human brainstem sites involved in perinatal hypoxia-ischemia

Journal of Comparative Neurology

Volumn 427, Issue 2, 2000, Pages 196-208

  Panigrahy, Ashok ^a   Rosenberg, Paul A ^a   Assmann, Susan ^b   Foley, Erin C ^a   Kinney, Hannah C ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NEW ENGLAND RESEARCH INSTITUTES   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

AMPA receptor; Excitotoxicity; Kainate receptor; NMDA receptor; Nucleus of the solitary tract

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; GLUTAMATE RECEPTOR; GLUTAMIC ACID; GLUTAMINE; KAINIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID;

ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRAIN MATURATION; BRAIN STEM; CELL MATURATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; FETUS; HUMAN; HUMAN TISSUE; HYPOXIA; IMAGE ANALYSIS; ISCHEMIA; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR BINDING;

2-AMINO-5-PHOSPHONOVALERATE; ADULT; AGED; ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; BRAIN STEM; CHILD, PRESCHOOL; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GLYCINE; HUMANS; HYPOXIA-ISCHEMIA, BRAIN; INFANT; INFANT, NEWBORN; MIDDLE AGED; NEUROPROTECTIVE AGENTS; PHENCYCLIDINE; PREGNANCY; RECEPTORS, AMPA; RECEPTORS, GLUTAMATE; RECEPTORS, GLYCINE; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, PHENCYCLIDINE; SUDDEN INFANT DEATH;

EID: 0034645464     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-9861(20001113)427:2<196::AID-CNE3>3.0.CO;2-9     Document Type: Article

References (59)

1. Role of glutamate as the central neurotransmitter in the hypoxic ventilatory response
2. AMPA/kainate receptors modulate the survival in vitro of embryonic brainstem cells
3. 3H]5,7-dichlorokynurenic acid, a novel radioligand labels NMDA receptor-associated glycine binding sites
4. GABA(A), NMDA and AMPA receptors: A developmentally regulated 'menage a trois'
5. Non-NMDA receptors modulate respiratory drive in fetal sheep
6. The molecular basis of NMDA receptor subtypes: Native receptor diversity is predicted by subunit composition
7. The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death
8. Magnesium ions increase binding affinities of dissociative anesthetic receptors but not NMDA receptors in rat brain
9. Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A
10. Mechanisms of cerebral injury in perinatal asphyxia and strategies for prevention
11. Mg 2+-dependant modification of the N-methyl-D-aspartate receptor following graded hypoxia in the cerebral cortex of newborn piglets
12. Characterization of ventilatory responses to hypoxia in neonatal rats
13. Evidence for transient perinatal glutamatergic innervation of globus pallidus
14. Current concepts of hypoxic-ischemic cerebral injury in the term newborn
15. Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain
16. Peripheral chemoreceptors respond to hypoxia in pontine-lesioned fetal lambs in utero
17. Hypoxic and ischemic disorders of infants and children
18. Glutamate receptors in cortical plasticity: Molecular and cellular biology
19. A glycine site associated with N-methyl-D-aspartate receptors: Characterization and identification of a new class of antagonists
20. Perinatal neuropathology
21. 'Reactive gliosis' in the medulla oblongata of victims of the sudden infant death syndrome
22. Decreased muscarinic receptor binding in the arcuate nucleus in sudden infant death syndrome
23. Non-NMDA receptor-mediated neurotoxicity in cortical culture
24. AMPA elicits long-lasting, partly hypothermia-sensitive calcium responses in acutely dissociated or cultured embryonic brainstem cells
25. Molecular diversity of the NMDA receptor channel
26. Ligand affinities at recombinant N-methyl-D-aspartate receptors depend on subunit composition
27. Regional, developmental and interspecies expression of the four NMDAR2 subunits, examined using monoclonal antibodies
28. Effect of N-methyl-D-aspartate-receptor blockade on hypoxic ventilatory response in unanesthetized piglets
29. Excitatory amino acids as a final common pathway for neurologic disorders
30. Ontogeny of NMDA R1 subunit protein expression in five regions of rat brain
31. N-methyl-Daspartate: Different subunit requirements for binding of glutamate antagonists, glycine antagonists, and channel-blocking agents
32. AMPA receptor protein in developing rat brain: Glutamate receptor-1 expression and localization change at regional cellular, and subcellular levels with maturation
33. Depressed ventilatory response to hypoxia in hypothermic newborn piglets: Role of glutamate
34. Physiological and pathological roles of excitatory amino acids during central nervous system development
35. Differential ontogenic development of three receptors comprising the NMDA receptor/channel complex in rat hippocampus
36. 3H-glycine binding sites in rat brain by quantitative receptor autoradiography
37. Functional change of NMDA receptors related to enhancement of susceptibility to neurotoxicity in the developing pontine nucleus
38. In vivo release of glutamate in nucleus tractus solitarii of the rat during hypoxia
39. Heteromeric NMDA receptors: Molecular and functional distinction of subtypes
40. Developmental and regional expression in the rat brain and functional properties of four NMDA receptors
41. 3H-CGP 39653 in rat brain
42. Developmental change in voltage dependency of NMDA receptor-mediated response in nucleus tractus solitarii neurons
43. Molecular diversity of glutamate receptors and implications for brain function
44. NMDA and non-NMDA receptors are co- localized at excitatory synapses of rat hypoglossal motoneurons
45. NMDA receptors mediate peripheral chemoreceptor afferent input in the conscious rat
46. 3H- kainate binding in human brainstem sites vulnerable to perinatal hypoxia-ischemia
47. Differential expression of three glutamate receptor genes in the developing rat brain: An in-situ hybridization study
48. N-methyl-D-aspartate receptor proteins NR2A and NR2B are differentially distributed in the developing rat central nervous system as revealed by subunit-specific antibodies
49. Involvement of the N-methyl-D-aspartate (NMDA) receptor in synapse elimination during cerebellar development
50. Modification of the glycine (co-activator) binding site of the N-methyl-Daspartate receptor in the guinea pig fetus brain during development following hypoxia
51. Prevention of normally occurring and deafferentation-induced neuronal death in chick brainstem auditory neurons by periodic blockade of AMPA/kainate receptors
52. Developmental and regional expression of NMDA receptor subtypes containing the NR2D subunit in rat brain
53. 3H-strychnine as the ligand
54. Different sensitivities of NMDA receptor subtypes to noncompetitive antagonists
55. Heterogeneity of the N-methyl-D-aspartate ionosphere complex in rat brain, as revealed by ligand-binding techniques
56. Excitatory amino acid receptors in the brain: Membrane binding and receptor autoradiographic approaches
57. Phasic and long-term depression in brainstem nucleus tractus solitarius neurons: Differing roles of AMPA receptor desensitization
58. Expression of mRNAs encoding subunits of the N-methyl-D-aspartate receptor in cultured cortical neurons