Mg2+-dependent modification of the N-methyl-D-aspartate receptor following graded hypoxia in the cerebral cortex of newborn piglets

Neuroscience

Volumn 92, Issue 2, 1999, Pages 685-692

  Fritz, K I ^a   Mishra, O P ^a   Delivoria Papadopoulos, M ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Hypoxia; Magnesium; Newborn; NMDA receptor; Phosphorylation

Indexed keywords

CREATINE PHOSPHATE; DIZOCILPINE MALEATE; GLUCOSE; MAGNESIUM ION; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; AMINO ACID RECEPTOR BLOCKING AGENT; MAGNESIUM;

ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; BRAIN CORTEX; BRAIN DEVELOPMENT; BRAIN HYPOXIA; BRAIN LEVEL; BRAIN OXYGEN CONSUMPTION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DEPHOSPHORYLATION; ENERGY METABOLISM; GLUCOSE BLOOD LEVEL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BLOCKING; RECEPTOR INTRINSIC ACTIVITY; SWINE; ANIMAL; ANOXIA; CHANNEL GATING; DRUG EFFECT; METABOLISM; PHYSIOLOGY;

ANIMALS; ANIMALS, NEWBORN; ANOXIA; CEREBRAL CORTEX; DIZOCILPINE MALEATE; ENERGY METABOLISM; EXCITATORY AMINO ACID ANTAGONISTS; ION CHANNEL GATING; MAGNESIUM; PHOSPHOCREATINE; RECEPTORS, N-METHYL-D-ASPARTATE; SWINE;

EID: 0032587986     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(98)00761-1     Document Type: Article

References (48)

1. Albers G., Goldberg M.P., Choi D.W. N-Methyl-D-aspartate antagonists: ready for clinical trial in brain ischemia? Ann. Neurol. 25:1989;398-403.
2. Burgard E.C., Hablitz J.J. Developmental changes in the voltage-dependence of neocortical NMDA responses. Brain Res. 80:1994;275-278.
3. 2+ block of NMDA-receptor channels as a mechanism of modulation. Nature. 356:1992;521-523.
4. 2+ in acutely isolated hippocampal neurons. J. Neurophysiol. 73:1995;515-524.
5. Collingridge G.L., Lester R.A. Excitatory amino acid receptors in the vertebrate central nervous system. Pharmac. Rev. 40:1989;145-210.
6. DiGiacomo J., Pane C., Gwiazdowski S., Mishra O.P., Delivoria-Papadopoulos M. Effect of graded hypoxia on brain cell membrane injury in newborn piglets. Biol. Neonate. 61:1992;25-52.
7. Edmonds B., Gibb A.J., Colquhoun D. Mechanisms of activation of glutamate receptors and the time course of excitatory synaptic currents. A. Rev. Physiol. 57:1995;495-519.
8. Ehlers M.D., Tingley W.G., Huganir R.L. Regulated subcellular distribution of the NR1 subunit of the NMDA receptor. Science. 269:1995;1734-1737.
9. Fritz K.I., Groenendaal F., McGowan J.E., Mishra O.P., Delivoria-Papadopoulos M. Effect of cerebral hypoxia on NMDA receptor binding characteristics after treatment with 3-(carboxypiperazin-4-yl)propyl-1-phosphonic acid (CPP) in newborn piglets. Brain Res. 729:1996;66-74.
10. Golding E.M., Vink R. Inhibition of phospholipase C with neomycin improves metabolic and neurologic outcome following traumatic brain injury. Brain Res. 668:1994;46-53.
11. Grether J.K., Nelson K.B., Emery E.S., Cummins S.K. Prenatal and perinatal factors and cerebral palsy in very low birth weight infants. J. Pediat. 128:1996;407-414.
12. Harik S.I., Douli G.H., Dick A.P.K. Specific ouabain binding to brain microvessels and choroid plexus. J. cerebr. Blood Flow Metab. 5:1985;6-160.
13. Harrison V., Peat G. Red blood cell magnesium and hypoxic-ischemic encephalopathy. Early Human Dev. 47:1997;287-296.
14. Hoffman D., McGowan J.E., Marro P.J., Mishra O.P., Delivoria-Papadopoulos M. Hypoxia-induced modification of the N-methyl-D-aspartate receptor in the brain of the newborn piglet. Neurosci. Lett. 167:1994;156-160.
15. 4 infusion on NMDA receptor binding characteristics during cerebral cortical hypoxia in the newborn piglet. Brain Res. 644:1994;144-149.
16. 2+ blockade of NMDA receptors. Neurosci. Lett. 173:1994;75-78.
17. Ikonomidou C., Turski L. Neurodegenerative disorders: clues from glutamate and energy metabolism. Crit. Rev. Neurobiol. 10:1996;239-263.
18. Imaizumi S., Kayama T., Suzuki J. Chemiluminescence in hypoxic brain - the first report. Correlation between energy metabolism and free radical reaction. Stroke. 15:1984;1061-1065.
19. ++ of N-methyl-D-aspartate channels. Biophys. J. 57:1990;1085-1090.
20. Johnston M., McDonald M., Chen C. and Trescher W. (1991) Role of excitatory amino acid receptors in perinatal hypoxic-ischemic brain injury. In Excitatory Amino Acids (eds Meldrum B. S., Moroni F., Simon R. P. and Woods J. H.), pp. 711-716. Raven, New York.
21. 2+ block of N-methyl-D-aspartate receptor-mediated synaptic potentials in developing visual cortex. Proc. natn. Acad. Sci. U.S.A. 90:1993;7114-7118.
22. Kawajiri S., Dingledine R. Multiple structural determinants of voltage-dependent magnesium block in recombinant NMDA receptors. Neuropharmacology. 32:1993;1203-1211.
23. Kupper J., Ascher P., Neyton J. Probing the pore region of recombinant N-methyl-D-aspartate channels using external and internal magnesium block. Proc. natn. Acad. Sci. U.S.A. 93:1996;8648-8653.
24. Lamprecht W., Stein P., Heinz F. and Weisser H. (1974) Creatine phosphate. In Methods of Enzymatic Analysis (ed. Bergmeyer H. U.), pp. 1777-1781. Academic, New York.
25. ++ of the NMDA-activated channel in cultured rat neurons. J. Physiol. 491:1996;121-135.
26. Lowry O., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J. biol. Chem. 193:1951;265-275.
27. MacDonald H.M., Mulligan J.C., Allen A.C., Taylor P.M. Neonatal asphyxia. I. Relationship of obstetric and neonatal complications to neonatal mortality in 38,405 consecutive deliveries. J. Pediat. 96:1980;898-902.
28. McDonald J.W., Johnston M.V. Physiological and pathological roles of excitatory amino acids during central nervous system development. Brain Res. 15:1990;41-70.
29. McDonald J.W., Johnston M.V. Excitatory amino acid neurotoxicity in the developing brain. NIDA Res. Monogr. Ser. 133:1993;185-205.
30. 31P magnetic resonance spectroscopy and behavioral studies. J. Neurotrauma. 5:1998;17-31.
31. McIntosh T.K., Vink R., Yamakami I., Faden A.I. Magnesium protects against neurological deficit after brain injury. Brain Res. 482:1989;252-260.
32. Mishra O.P., Delivoria-Papadopoulos M. Lipid peroxidation in developing fetal guinea pig brain during normoxia and hypoxia. Devl Brain Res. 45:1989;129-135.
33. Mishra O.P., Delivoria-Papadopoulos M. NMDA receptor modification in the fetal guinea pig brain during hypoxia. Neurochem. Res. 17:1992;1211-1216.
34. Monaghan D., Bridges R., Cotman C. The excitatory amino acid receptors: their classes, pharmacology and distinct properties in the function of the central nervous system. A. Rev. Pharmac. Toxic. 29:1989;365-402.
35. Nabekura J., Kawamoto I., Akaike N. Developmental change in voltage dependency of NMDA receptor-mediated response in nucleus tractus solitarii neurons. Brain Res. 648:1994;152-156.
36. Nikoa S., Chance B., Smith D.S., Mayevsky A., Reilly M.P., Alter C., Asakura T. Cerebral energy metabolism and oxygen state during hypoxia in neonate and adult dogs. Pediat. Res. 28:1990;54-62.
37. Puza S., Goel R., Hoffman D., Mishra O.P., Morgan M.A., Delivoria-Papadopoulos M. Pretreatment with magnesium protects NMDA receptor in fetal guinea pig brain during hypoxia. Prenatal Neonatal Med. 1:1996;349-354.
38. Raymond L.A., Tingley W.G., Blackstone C.D., Roche K.W., Huganir R.L. Glutamate receptor modulation by protein phosphorylation. J. Physiol., Paris. 88:1994;181-192.
39. 3H]MK-801 binding to the NMDA receptor/ionophore complex is regulated by divalent cations: evidence for multiple regulatory sites. Eur. J. Pharmac. 151:1988;103-112.
40. Reynolds I.J., Miller R.J. Allosteric modulation of N-methyl-D-aspartate receptors. Adv. Pharmac. 21:1990;101-126.
41. Roche K.W., Tingley W.G., Huganir R.L. Glutamate receptor phosphorylation and synaptic plasticity. Curr. Biol. 4:1994;383-388.
42. Schendel D.E., Berg C.J., Yeargin-Allsopp M., Boyle C.A. Prenatal magnesium sulfate exposure and the risk for cerebral palsy or mental retardation among very low-birth-weight children aged 3 to 5 years. J. Am. med. Ass. 276:1996;1805-1810.
43. Sharma G., Stevens C.F. Interactions between two divalent ion binding sites in N-methyl-D-aspartate receptor channels. Proc. natn. Acad. Sci. U.S.A. 93:1996;14170-14175.
44. Strecker G.J., Jackson M.B., Dudek F.E. Blockade of NMDA-activated channels by magnesium in the immature rat hippocampus. J. Neurophysiol. 72:1994;1538-1548.
45. Volpe J. J. (1987) Neurology of the Newborn. W. B. Saunders, Philadelphia, PA.
46. 3H]MK-801 to the N-methyl-D-aspartate receptor: pharmacological evidence for the existence of a polyamine recognition site. Molec. Pharmac. 36:1989;575-581.
47. Wolfe L.S. Eicosanoids: prostaglandins, thromboxanes, leukotrienes, and other derivatives of carbon-20 unsaturated fatty acids. J. Neurochem. 38:1982;1-14.
48. 2+ blockade of NMDA current in mechanically injured neurons. Science. 274:1996;1921-1923.