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Volumn 76, Issue 1, 2000, Pages 64-72

μ Opioid receptor: Role for the amino terminus as a determinant of ligand binding affinity

Author keywords

Endomorphin; Fentanyl; Methadone; Morphine; Opioid receptor

Indexed keywords

BREMAZOCINE; CYCLAZOCINE; ENDOMORPHIN 1; ENDOMORPHIN 2; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; FENTANYL; METHADONE; MORPHINE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; NALOXONE; OPIATE PEPTIDE;

EID: 0034629233     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(99)00332-0     Document Type: Article
Times cited : (55)

References (55)
  • 1
    • 0030040907 scopus 로고    scopus 로고
    • The conserved aspartate residue in the third putative transmembrane domain of the δ-opioid receptor is not the anionic counterpart for cationic opiate binding but is a constituent of the receptor binding site
    • Befort K., Tabbara L., Bausch S., Chavkin C., Evans C., Kieffer B. The conserved aspartate residue in the third putative transmembrane domain of the δ-opioid receptor is not the anionic counterpart for cationic opiate binding but is a constituent of the receptor binding site. Mol. Pharmacol. 49:1996;216-223.
    • (1996) Mol. Pharmacol. , vol.49 , pp. 216-223
    • Befort, K.1    Tabbara, L.2    Bausch, S.3    Chavkin, C.4    Evans, C.5    Kieffer, B.6
  • 2
    • 0029937609 scopus 로고    scopus 로고
    • Role of aromatic transmembrane residues of the δ-opioid receptor in ligand recognition
    • Befort K., Tabbara L., Kling D., Maigret B., Kieffer B. Role of aromatic transmembrane residues of the δ-opioid receptor in ligand recognition. J. Biol. Chem. 271:1996;10161-10168.
    • (1996) J. Biol. Chem. , vol.271 , pp. 10161-10168
    • Befort, K.1    Tabbara, L.2    Kling, D.3    Maigret, B.4    Kieffer, B.5
  • 4
    • 0031973007 scopus 로고    scopus 로고
    • Mutagenesis of a single amino acid in the rat μ-opioid receptor discriminates ligand binding
    • Bot G., Blake A.D., Li S., Reisine T. Mutagenesis of a single amino acid in the rat μ-opioid receptor discriminates ligand binding. J. Neurochem. 70:1998;358-365.
    • (1998) J. Neurochem. , vol.70 , pp. 358-365
    • Bot, G.1    Blake, A.D.2    Li, S.3    Reisine, T.4
  • 5
    • 0027335582 scopus 로고
    • o mediates the coupling of the μ opioid receptor to adenylyl cyclase in cloned neural cells and brains
    • o mediates the coupling of the μ opioid receptor to adenylyl cyclase in cloned neural cells and brains. Proc. Natl. Acad. Sci. U. S. A. 90:1993;4062-4066.
    • (1993) Proc. Natl. Acad. Sci. U. S. A. , vol.90 , pp. 4062-4066
    • Carter, B.D.1    Medzihradsky, F.2
  • 6
    • 0027202213 scopus 로고
    • Molecular cloning and functional expression of a μ-opioid receptor from rat brain
    • Chen Y., Mestek A., Liu J., Hurley J.A., Yu L. Molecular cloning and functional expression of a μ-opioid receptor from rat brain. Mol. Pharmacol. 44:1993;8-12.
    • (1993) Mol. Pharmacol. , vol.44 , pp. 8-12
    • Chen, Y.1    Mestek, A.2    Liu, J.3    Hurley, J.A.4    Yu, L.5
  • 8
    • 0033516657 scopus 로고    scopus 로고
    • Identification of an interaction between residue 6 of the natural peptide ligand and a distinct residue within the amino-terminal tail of the secretin receptor
    • Dong M., Wang Y., Hadac E.M., Pinon D.L., Holicky E., Miller L.J. Identification of an interaction between residue 6 of the natural peptide ligand and a distinct residue within the amino-terminal tail of the secretin receptor. J. Biol. Chem. 274:1999;19161-19167.
    • (1999) J. Biol. Chem. , vol.274 , pp. 19161-19167
    • Dong, M.1    Wang, Y.2    Hadac, E.M.3    Pinon, D.L.4    Holicky, E.5    Miller, L.J.6
  • 10
    • 0027275029 scopus 로고
    • Primary structures and expression from a cDNA of rat opioid receptor delta- And mu-subtypes
    • Fukuda K., Kato S., Mori K., Nishi M., Takeshima H. Primary structures and expression from a cDNA of rat opioid receptor delta- and mu-subtypes. FEBS Lett. 327:1993;311-314.
    • (1993) FEBS Lett. , vol.327 , pp. 311-314
    • Fukuda, K.1    Kato, S.2    Mori, K.3    Nishi, M.4    Takeshima, H.5
  • 11
    • 0029131679 scopus 로고
    • Identification of the amino acid residues involved in selective agonist binding in the first extracellular loop of the δ- And μ-opioid receptors
    • Fukuda K., Terasako K., Kato S., Mori K. Identification of the amino acid residues involved in selective agonist binding in the first extracellular loop of the δ- and μ-opioid receptors. FEBS Lett. 373:1995;177-181.
    • (1995) FEBS Lett. , vol.373 , pp. 177-181
    • Fukuda, K.1    Terasako, K.2    Kato, S.3    Mori, K.4
  • 13
    • 0024459590 scopus 로고
    • Multiple opioid receptors: Ligand selectivity profiles and binding site signatures
    • Goldstein A., Naidu A. Multiple opioid receptors: ligand selectivity profiles and binding site signatures. Mol. Pharmacol. 36:1989;265-272.
    • (1989) Mol. Pharmacol. , vol.36 , pp. 265-272
    • Goldstein, A.1    Naidu, A.2
  • 16
    • 0029013360 scopus 로고
    • Analysis of selective binding epitopes for the κ-opioid receptor antagonist nor-binaltorphimine
    • Hjorth S.A., Thirstrup K., Grandy D.K., Schwartz T.W. Analysis of selective binding epitopes for the κ-opioid receptor antagonist nor-binaltorphimine. Mol. Pharmacol. 47:1995;1089-1094.
    • (1995) Mol. Pharmacol. , vol.47 , pp. 1089-1094
    • Hjorth, S.A.1    Thirstrup, K.2    Grandy, D.K.3    Schwartz, T.W.4
  • 17
    • 0019976367 scopus 로고
    • Solubilization and characterization of active opiate binding sites from mammalian brain
    • Howells R.D., Gioannini T., Hiller J.M., Simon E.J. Solubilization and characterization of active opiate binding sites from mammalian brain. J. Pharmacol. Exp. Ther. 222:1982;629-634.
    • (1982) J. Pharmacol. Exp. Ther. , vol.222 , pp. 629-634
    • Howells, R.D.1    Gioannini, T.2    Hiller, J.M.3    Simon, E.J.4
  • 18
    • 0027052952 scopus 로고
    • The δ opioid receptor: Isolation of a cDNA by expression cloning and pharmacological characterization
    • Kieffer B.L., Befort K., Gaveriaux-Ruff C., Hirth C.G. The δ opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization. Proc. Natl. Acad. Sci. U. S. A. 89:1992;12048-12052.
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 12048-12052
    • Kieffer, B.L.1    Befort, K.2    Gaveriaux-Ruff, C.3    Hirth, C.G.4
  • 20
    • 0027444691 scopus 로고
    • A single residue, aspartic acid 95, in the δ opioid receptor specifies selective high affinity agonist binding
    • Kong H., Raynor K., Yasuda K., Moe S.T., Portoghese P.S., Bell G.I., Reisine T. A single residue, aspartic acid 95, in the δ opioid receptor specifies selective high affinity agonist binding. J. Biol. Chem. 268:1993;23055-23058.
    • (1993) J. Biol. Chem. , vol.268 , pp. 23055-23058
    • Kong, H.1    Raynor, K.2    Yasuda, K.3    Moe, S.T.4    Portoghese, P.S.5    Bell, G.I.6    Reisine, T.7
  • 21
    • 0021891884 scopus 로고
    • Assembly of asparagine-linked oligosaccharides
    • Kornfeld R., Kornfeld S. Assembly of asparagine-linked oligosaccharides. Annu. Rev. Biochem. 54:1985;631-664.
    • (1985) Annu. Rev. Biochem. , vol.54 , pp. 631-664
    • Kornfeld, R.1    Kornfeld, S.2
  • 22
    • 0027403710 scopus 로고
    • Mu and delta opioid receptors differentially couple to G protein subtypes in membranes of human neuroblastoma SH-SY5Y cells
    • Laugwitz K.-I., Offermanns S., Spicher K., Schultz G. Mu and delta opioid receptors differentially couple to G protein subtypes in membranes of human neuroblastoma SH-SY5Y cells. Neuron. 10:1993;233-242.
    • (1993) Neuron , vol.10 , pp. 233-242
    • Laugwitz, K.-I.1    Offermanns, S.2    Spicher, K.3    Schultz, G.4
  • 23
    • 0032901479 scopus 로고    scopus 로고
    • Regulation of opioid receptor activities
    • Law P.-Y., Loh H.H. Regulation of opioid receptor activities. J. Pharmacol. Exp. Ther. 289:1999;607-624.
    • (1999) J. Pharmacol. Exp. Ther. , vol.289 , pp. 607-624
    • Law, P.-Y.1    Loh, H.H.2
  • 24
    • 0032031040 scopus 로고    scopus 로고
    • μ Opioid receptor knockout in mice: Effects on ligand-induced analgesia and morphine lethality
    • Loh H.H., Liu H.C., Cavalli A., Yang W., Chen Y.F., Wei L.N. μ Opioid receptor knockout in mice: effects on ligand-induced analgesia and morphine lethality. Mol. Brain Res. 54:1998;321-326.
    • (1998) Mol. Brain Res. , vol.54 , pp. 321-326
    • Loh, H.H.1    Liu, H.C.2    Cavalli, A.3    Yang, W.4    Chen, Y.F.5    Wei, L.N.6
  • 26
    • 0028887626 scopus 로고
    • Opioid receptor mRNA expression in the rat CNS: Anatomical and functional implications
    • Mansour A., Fox C.A., Akil H., Watson S.J. Opioid receptor mRNA expression in the rat CNS: anatomical and functional implications. Trends Neurosci. 18:1995;22-29.
    • (1995) Trends Neurosci. , vol.18 , pp. 22-29
    • Mansour, A.1    Fox, C.A.2    Akil, H.3    Watson, S.J.4
  • 28
    • 0029017044 scopus 로고
    • A chimeric study of the molecular basis of affinity and selectivity of the κ and the δ opioid receptors
    • Meng F., Hoversten M.T., Thompson R.C., Taylor L., Watson S.J., Akil H. A chimeric study of the molecular basis of affinity and selectivity of the κ and the δ opioid receptors. J. Biol. Chem. 270:1995;12730-12736.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12730-12736
    • Meng, F.1    Hoversten, M.T.2    Thompson, R.C.3    Taylor, L.4    Watson, S.J.5    Akil, H.6
  • 32
    • 0029093909 scopus 로고
    • Model of human chorionic gonadotropin and lutropin receptor interaction that explains signal transduction of the glycoprotein hormones
    • Moyle W.R., Campbell R.K., Rao S.N., Ayad N.G., Bernard M.P., Han Y., Wang Y. Model of human chorionic gonadotropin and lutropin receptor interaction that explains signal transduction of the glycoprotein hormones. J. Biol. Chem. 270:1995;20020-20031.
    • (1995) J. Biol. Chem. , vol.270 , pp. 20020-20031
    • Moyle, W.R.1    Campbell, R.K.2    Rao, S.N.3    Ayad, N.G.4    Bernard, M.P.5    Han, Y.6    Wang, Y.7
  • 33
    • 1842335688 scopus 로고    scopus 로고
    • Novel "restoration of function" mutagenesis strategy to identify amino acids of the δ-opioid receptor involved in ligand binding
    • Pepin M.-C., Yue S.Y., Roberts E., Wahlestedt C., Walker P. Novel "restoration of function" mutagenesis strategy to identify amino acids of the δ-opioid receptor involved in ligand binding. J. Biol. Chem. 272:1997;9260-9267.
    • (1997) J. Biol. Chem. , vol.272 , pp. 9260-9267
    • Pepin, M.-C.1    Yue, S.Y.2    Roberts, E.3    Wahlestedt, C.4    Walker, P.5
  • 34
    • 0028038183 scopus 로고
    • Human formyl peptide receptor ligand binding domain(s)
    • Perez H.D., Vilander L., Andrews W.H., Holmes R. Human formyl peptide receptor ligand binding domain(s). J. Biol. Chem. 269:1994;22485-22487.
    • (1994) J. Biol. Chem. , vol.269 , pp. 22485-22487
    • Perez, H.D.1    Vilander, L.2    Andrews, W.H.3    Holmes, R.4
  • 35
    • 0029856581 scopus 로고    scopus 로고
    • Functional analysis of cloned opioid receptors in transfected cell lines
    • Piros E.T., Hales T.G., Evans C.J. Functional analysis of cloned opioid receptors in transfected cell lines. Neurochem. Res. 21:1996;1277-1285.
    • (1996) Neurochem. Res. , vol.21 , pp. 1277-1285
    • Piros, E.T.1    Hales, T.G.2    Evans, C.J.3
  • 36
    • 0028169458 scopus 로고
    • Ability of δ-opioid receptors to interact with multiple G-proteins is independent of receptor density
    • Prather P.L., McGinn T.M., Erickson L.J., Evans C.J., Loh H.H., Law P.Y. Ability of δ-opioid receptors to interact with multiple G-proteins is independent of receptor density. J. Biol. Chem. 269:1994;21293-21302.
    • (1994) J. Biol. Chem. , vol.269 , pp. 21293-21302
    • Prather, P.L.1    McGinn, T.M.2    Erickson, L.J.3    Evans, C.J.4    Loh, H.H.5    Law, P.Y.6
  • 37
    • 0028006303 scopus 로고
    • Pharmacological characterization of the cloned κ-, δ-, and μ-opioid receptors
    • Raynor K., Kong H., Chen Y., Yasuda K., Yu L., Bell G.I., Reisine T. Pharmacological characterization of the cloned κ-, δ-, and μ-opioid receptors. Mol. Pharmacol. 45:1994;330-334.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 330-334
    • Raynor, K.1    Kong, H.2    Chen, Y.3    Yasuda, K.4    Yu, L.5    Bell, G.I.6    Reisine, T.7
  • 38
    • 0029908852 scopus 로고    scopus 로고
    • Sensitivity of opioid receptor binding to N-substituted maleimides and methanethiosulfonate derivatives
    • Shahrestanifar M., Howells R.D. Sensitivity of opioid receptor binding to N-substituted maleimides and methanethiosulfonate derivatives. Neurochem. Res. 21:1996;1295-1299.
    • (1996) Neurochem. Res. , vol.21 , pp. 1295-1299
    • Shahrestanifar, M.1    Howells, R.D.2
  • 39
    • 0029863220 scopus 로고    scopus 로고
    • Studies on inhibition of μ and δ opioid receptor binding by dithiothreitol and N-ethylmaleimide
    • Shahrestanifar M., Wang W.W., Howells R.D. Studies on inhibition of μ and δ opioid receptor binding by dithiothreitol and N-ethylmaleimide. J. Biol. Chem. 271:1996;5505-5512.
    • (1996) J. Biol. Chem. , vol.271 , pp. 5505-5512
    • Shahrestanifar, M.1    Wang, W.W.2    Howells, R.D.3
  • 43
    • 0028170438 scopus 로고
    • μ-Opioid receptor: Charged transmembrane domain amino acids are critical for agonist recognition and intrinsic activity
    • Surratt C.K., Johnson P.S., Moriwaki A., Seidleck B.K., Blaschak C.J., Wang J.B., Uhl G.R. μ-Opioid receptor: charged transmembrane domain amino acids are critical for agonist recognition and intrinsic activity. J. Biol. Chem. 269:1994;20548-20553.
    • (1994) J. Biol. Chem. , vol.269 , pp. 20548-20553
    • Surratt, C.K.1    Johnson, P.S.2    Moriwaki, A.3    Seidleck, B.K.4    Blaschak, C.J.5    Wang, J.B.6    Uhl, G.R.7
  • 44
    • 0029873472 scopus 로고    scopus 로고
    • Construction of a high affinity switch in the κ-opioid receptor
    • Thirstrup K., Elling C.E., Hjorth S.A., Schwartz T.W. Construction of a high affinity switch in the κ-opioid receptor. J. Biol. Chem. 271:1996;7875-7878.
    • (1996) J. Biol. Chem. , vol.271 , pp. 7875-7878
    • Thirstrup, K.1    Elling, C.E.2    Hjorth, S.A.3    Schwartz, T.W.4
  • 45
    • 0027504836 scopus 로고
    • Cloning and pharmacological characterization of a rat mu opioid receptor
    • Thompson R.C., Mansour A., Akil H., Watson S.J. Cloning and pharmacological characterization of a rat mu opioid receptor. Neuron. 11:1993;903-913.
    • (1993) Neuron , vol.11 , pp. 903-913
    • Thompson, R.C.1    Mansour, A.2    Akil, H.3    Watson, S.J.4
  • 46
    • 10144241052 scopus 로고    scopus 로고
    • Involvement of Trp-284, Val-296, and Val-297 of the human δ-opioid receptor in binding of δ-selective ligands
    • Valiquette M., Vu H.K., Yue S.Y., Wahlestedt C., Walker P. Involvement of Trp-284, Val-296, and Val-297 of the human δ-opioid receptor in binding of δ-selective ligands. J. Biol. Chem. 271:1996;18789-18796.
    • (1996) J. Biol. Chem. , vol.271 , pp. 18789-18796
    • Valiquette, M.1    Vu, H.K.2    Yue, S.Y.3    Wahlestedt, C.4    Walker, P.5
  • 47
    • 0026513428 scopus 로고
    • Studies on the role of amino acids 38-45 in the expression of a functional thyrotropin receptor
    • Wadsworth H.L., Russo D., Nagayama Y., Chazenbalk G.D., Rapoport B. Studies on the role of amino acids 38-45 in the expression of a functional thyrotropin receptor. Mol. Endocrinol. 6:1992;394-398.
    • (1992) Mol. Endocrinol. , vol.6 , pp. 394-398
    • Wadsworth, H.L.1    Russo, D.2    Nagayama, Y.3    Chazenbalk, G.D.4    Rapoport, B.5
  • 49
    • 0028143479 scopus 로고
    • Human κ opiate receptor second extracellular loop elevates dynorphin's affinity for human μ/κ chimeras
    • Wang J.B., Johnson P.S., Wu J.M., Wang W.F., Uhl G.R. Human κ opiate receptor second extracellular loop elevates dynorphin's affinity for human μ/κ chimeras. J. Biol. Chem. 269:1994;25966-25969.
    • (1994) J. Biol. Chem. , vol.269 , pp. 25966-25969
    • Wang, J.B.1    Johnson, P.S.2    Wu, J.M.3    Wang, W.F.4    Uhl, G.R.5
  • 50
    • 0029586680 scopus 로고
    • Studies on μ and δ opioid receptor selectivity utilizing chimeric and site-mutagenized receptors
    • Wang W.W., Shahrestanifar M., Jin J., Howells R.D. Studies on μ and δ opioid receptor selectivity utilizing chimeric and site-mutagenized receptors. Proc. Natl. Acad. Sci. U. S. A. 92:1995;12436-12440.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 12436-12440
    • Wang, W.W.1    Shahrestanifar, M.2    Jin, J.3    Howells, R.D.4
  • 51
    • 0032402450 scopus 로고    scopus 로고
    • Molecular basis of receptor/G-protein-coupling selectivity
    • Wess J. Molecular basis of receptor/G-protein-coupling selectivity. Pharmacol. Ther. 80:1998;231-264.
    • (1998) Pharmacol. Ther. , vol.80 , pp. 231-264
    • Wess, J.1
  • 52
    • 0029045917 scopus 로고
    • The third extracellular loop of the μ opioid receptor is important for agonist selectivity
    • Xue J.-C., Chen C., Zhu J., Kunapuli S.P., de Riel J.K., Yu L., Liu-Chen L.-Y. The third extracellular loop of the μ opioid receptor is important for agonist selectivity. J. Biol. Chem. 270:1995;12977-12979.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12977-12979
    • Xue, J.-C.1    Chen, C.2    Zhu, J.3    Kunapuli, S.P.4    De Riel, J.K.5    Yu, L.6    Liu-Chen, L.-Y.7
  • 53
    • 0026666733 scopus 로고
    • Identification of amino acid residues of rat angiotensin II receptor for ligand binding by site directed mutagenesis
    • Yamano Y., Ohyama K., Chaki S., Guo D.-F., Inagami T. Identification of amino acid residues of rat angiotensin II receptor for ligand binding by site directed mutagenesis. Biochem. Biophys. Res. Commun. 187:1992;1426-1431.
    • (1992) Biochem. Biophys. Res. Commun. , vol.187 , pp. 1426-1431
    • Yamano, Y.1    Ohyama, K.2    Chaki, S.3    Guo, D.-F.4    Inagami, T.5
  • 55
    • 0030933655 scopus 로고    scopus 로고
    • A potent and selective endogenous agonist for the μ-opiate receptor
    • Zadina J.E., Hackler L., Ge L.-J., Kastin A.J. A potent and selective endogenous agonist for the μ-opiate receptor. Nature. 386:1997;499-502.
    • (1997) Nature , vol.386 , pp. 499-502
    • Zadina, J.E.1    Hackler, L.2    Ge, L.-J.3    Kastin, A.J.4


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