Phosphorylation of the nuclear transport machinery down-regulates nuclear protein import in vitro

Journal of Biological Chemistry

Volumn 275, Issue 23, 2000, Pages 17848-17856

  Kehlenbach, Ralph H ^a   Gerace, Larry ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KARYOPHERIN; STAUROSPORINE;

ARTICLE; CELL TRANSPORT; CONTROLLED STUDY; DOWN REGULATION; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; CARRIER PROTEINS; CELL MEMBRANE PERMEABILITY; CELL NUCLEUS; ENZYME INHIBITORS; HELA CELLS; HUMANS; KARYOPHERINS; KINETICS; MICROCYSTINS; NUCLEAR ENVELOPE; NUCLEAR PROTEINS; OKADAIC ACID; PEPTIDES, CYCLIC; PHOSPHORYLATION; PROTEIN KINASES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; THIONUCLEOTIDES;

EID: 0034625427     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M001455200     Document Type: Article

References (54)

1. Stoffler, D., Fahrenkrog, B., and Aebi, U. (1999) Curr. Opin. Cell Biol. 11, 391-401
2. Mattaj, I. W., and Englmeier, L. (1998) Annu. Rev. Biochem. 67, 265-306
3. Görlich, D., and Kutay, U. (1999) Annu. Rev. Cell Dev. Biol. 15, 607-660
4. Nakielny, S., and Dreyfuss, G. (1999) Cell 99, 677-690
5. Dingwall, C., and Laskey, R. A. (1991) Trends Biochem. Sci. 16, 478-481
6. Siomi, H., and Dreyfuss, G. (1995) J. Cell Biol. 129, 551-560
7. Pollard, V. W., Michael, W. M., Nakielny, S., Siomi, M. C., Wang, F., and Dreyfuss, G. (1996) Cell 86, 985-994
8. Fischer, U., Huber, J., Boelens, W. C., Mattaj, I. W., and Lührmann, R. (1995) Cell 82, 475-483
9. Wen, W., Meinkoth, J. L., Tsien, R. Y., and Taylor, S. S. (1995) Cell 82, 463-473
10. Fornerod, M., Ohno, M., Yoshida, M., and Mattaj, I. W. (1997) Cell 90, 1051-1060
11. Fukuda, M., Asano, S., Nakamura, T., Adachi, M., Yoshida, M., Yanagida, M., and Nishida, E. (1997) Nature 390, 308-311
12. Coutavas, E., Ren, M., Oppenheim, J. D., D'Eustachio, P., and Rush, M. G. (1993) Nature 366, 585-587
13. Bischoff, F. R., Krebber, H., Smirnova, E., Dong, W., and Ponstingl, H. (1995) EMBO J 14, 705-715
14. Rexach, M., and Blobel, G. (1995) Cell 83, 683-692
15. Görlich, D., Pante, N., Kutay, U., Aebi, U., and Bischoff, F. R. (1996) EMBO J. 15, 5584-5594
16. Shah, S., Tugendreich, S., and Forbes, D. (1998) J. Cell Biol. 141, 31-49
17. Delphin, C., Guan, T., Melchior, F., and Gerace, L. (1997) Mol. Biol. Cell 8, 2379-2390
18. Kehlenbach, R. H., Dickmanns, A., Kehlenbach, A., Guan, T., and Gerace, L. (1999) J. Cell Biol. 145, 645-657
19. Yokoyama, N., Hayashi, N., Seki, T., Panté, N., Ohba, T., Nishii, K., Kuma, K., Hayashida, T., Miyata, T., Aebi, U., Fukui, M., and Nishimoto, T. (1995) Nature 376, 184-188
20. Wilken, N., Senecal, J. L., Scheer, U., and Dabauvalle, M. C. (1995) Eur. J. Cell Biol. 68, 211-219
21. Wu, J., Matunis, M. J., Kraemer, D., Blobel, G., and Coutavas, E. (1995) J. Biol. Chem. 270, 14209-14213
22. Panté, N., Bastos, R., McMorrow, I., Burke, B., and Aebi, U. (1994) J. Cell Biol. 126, 603-617
23. Mishra, K., and Parnaik, V. K. (1995) Exp. Cell Res. 216, 124-134
24. Radu, A., Moore, M. S., and Blobel, G. (1995) Cell 81, 215-222
25. Cordes, V. C., Reidenbach, S., Kohler, A., Stuurman, N., van Driel, R., and Franke, W. W. (1993) J. Cell Biol. 123, 1333-1344
26. Sukegawa, J., and Blobel, G. (1993) Cell 72, 29-38
27. Guan, T., Muller, S., Klier, G., Panté, N., Blevitt, J. M., Haner, M., Paschal, B., Aebi, U., and Gerace, L. (1995) Mol. Biol. Cell 6, 1591-1603
28. Melchior, F., and Gerace, L. (1998) Trends Cell Biol. 8, 175-179
29. Kaffman, A., and O'Shea, E. K. (1999) Annu. Rev. Cell Dev. Biol. 15, 291-339
30. Beals, C. R., Clipstone, N. A., Ho, S. N., and Crabtree, G. R. (1997) Genes Dev. 11, 824-834
31. Beals, C. R., Sheridan, C. M., Turck, C. W., Gardner, P., and Crabtree, G. R. (1997) Science 275, 1930-1934
32. Feldherr, C. M., and Akin, D. (1991) J. Cell Biol. 115, 933-939
33. Feldherr, C. M., and Akin, D. (1994) Exp. Cell Res. 215, 206-210
34. Feldherr, C., and Akin, D. (1995) Mol. Cell. Biol. 15, 7043-7049
35. Azuma, Y., Takio, K., Tabb, M. M., Vu, L., and Nomura, M. (1997) Biochimie (Paris) 79, 247-259
36. Miller, M. W., Caracciolo, M. R., Berlin, W. K., and Hanover, J. A. (1999) Arch. Biochem. Biophys. 367, 51-60
37. Melchior, F., Sweet, D. J., and Gerace, L. (1995) Methods Enzymol. 257, 279-291
38. Hu, T., Guan, T., and Gerace, L. (1996) J. Cell Biol. 134, 589-601
39. Paschal, B. M., and Gerace, L. (1995) J. Cell Biol. 129, 925-937
40. Kehlenbach, R. H., Dickmanns, A., and Gerace, L. (1998) J. Cell Biol. 141, 863-874
41. Adam, S. A., Marr, R. S., and Gerace, L. (1990) J. Cell Biol. 111, 807-816
42. Snow, C. M., Senior, A., and Gerace, L. (1987) J. Cell Biol. 104, 1143-1156
43. Klebe, C., Bischoff, F. R., Ponstingl, H., and Wittinghofer, A. (1995) Biochemistry 34, 639-647
44. Palacios, I., Weis, K., Klebe, C., Mattaj, I. W., and Dingwall, C. (1996) J. Cell Biol. 133, 485-494
45. Klemm, J. D., Beals, C. R., and Crabtree, G. R. (1997) Curr. Biol. 7, 638-644
46. Wolff, B., Sanglier, J. J., and Wang, Y. (1997) Chem. Biol. 4, 139-147
47. Eckstein, F. (1975) Angew. Chem. Int. Ed. Engl. 14, 160-166
48. Sheppeck, J. E., II, Gauss, C. M., and Chamberlin, A. R. (1997) Bioorg. Med. Chem. 5, 1739-1750
49. Allen, P. B., Kwon, Y. G., Nairn, A. C., and Greengard, P. (1998) J. Biol. Chem. 273, 4089-4095
50. Shibasaki, F., Price, E. R., Milan, D., and McKeon, F. (1996) Nature 382, 370-373
51. Robinson, J. P., Darzynkiewicz, Z., Dean, P. N., Dressier, L. G., Rabinovitch, P. S., Stewart, C. C., Tanke, H. J., and Wheeless, L. L., eds (1997) Current Protocols in Cytometry, John Wiley & Sons, Inc., New York
52. Favreau, C., Worman, H. J., Wozniak, R. W., Frappier, T., and Courvalin, J. C. (1996) Biochemistry 35, 8035-8044
53. Shah, S., and Forbes, D. J. (1998) Curr. Biol. 8, 1376-1386
54. Czubryt, M. P., Austria, J. A., and Pierce, G. N. (2000) J. Cell Biol. 148, 7-16