ATPase kinetic characterization and single molecule behavior of mutant human kinesin motors defective in microtubule-based motility

Biochemistry

Volumn 39, Issue 18, 2000, Pages 5265-5273

  Shimizu, Takashi ^a,b   Thorn, Kurt S ^b,c   Ruby, Aaron ^b   Vale, Ronald D ^b,c,d  

^a NATL INST FOR ADV INTERDISC RES   (Japan)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; KINESIN; TUBULIN;

ARTICLE; BINDING KINETICS; CONFORMATIONAL TRANSITION; ENZYME ACTIVITY; ENZYME KINETICS; HUMAN; HYDROLYSIS; MICROTUBULE ASSEMBLY; MOLECULAR BIOLOGY; MUTATION; NUCLEOTIDE TRANSPORT; PHOSPHATE TRANSPORT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN STRUCTURE; VELOCITY;

ADENOSINE TRIPHOSPHATASES; BINDING SITES; FLUORESCENCE; HUMANS; KINESIN; KINETICS; MICROTUBULES; MODELS, MOLECULAR; MOLECULAR MOTOR PROTEINS; MUTATION; PHOSPHATES; PROTEIN BINDING; PROTEIN FOLDING;

EID: 0034625119     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9928344     Document Type: Article

References (45)

1. Hirokawa, N. (1998) Science 279, 519-526.
2. Liao, G., and Gundersen, G. G. (1998) J. Biol. Chem. 273, 9797-9803.
3. Prahlad, V., Yoon, M., Moir, R. D., Vale, R. D., and Goldman, R. D. (1998) J. Cell Biol. 143, 159-170.
4. Vale, R. D., and Fletterick, R. J. (1997) Annu. Rev. Cell Dev. Biol. 12, 745-777.
5. Yang, J. T., Saxton, W. M., Stewart, R. J., Raff, E. C., and Goldstein, L. S. (1990) Science 249, 42-47.
6. Ray, S., Meyhofer, E., Milligan, R. A., and Howard, J. (1993) J. Cell Biol. 121, 1083-1093.
7. Schnitzer, M. J., and Block, S. M. (1997) Nature 388, 386-390.
8. Hua, W., Young, E. C., Fleming, M. L., and Gelles, J. (1997) Nature 388, 390-393.
9. Lohman, T. M., Thorn, K., and Vale, R. D. (1998) Cell 93, 9-12.
10. Ma, Y. Z., and Taylor, E. W. (1997) J. Biol. Chem. 272, 717-723.
11. Ma, Y.-Z., and Taylor, E. W. (1997) J. Biol. Chem. 272, 724-730.
12. Moyer, M. L., Gilbert, S. P., and Johnson, K. A. (1998) Biochemistry 37, 800-813.
13. Gilbert, S. P., Moyer, M. L., and Johnson, K. A. (1998) Biochemistry 37, 792-799.
14. Ma, Y. Z., and Taylor, E. W. (1995) Biochemistry 34, 13242-13251.
15. Hackney, D. D. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 6314-6318.
16. Gilbert, S. P., Webb, M. R., Brune, M., and Johnson, K. A. (1995) Nature 373, 671-676.
17. Kull, F. J., Sablin, E. P., Lau, R., Fletterick, R. J., and Vale, R. D. (1996) Nature 380, 550-555.
18. Sack, S., Muller, J., Marx, A., Thormahlen, M., Mandelkow, E. M., Brady, S. T., and Mandelkow, E. (1997) Biochemistry 36, 16155-16165.
19. Kozielski, F., Sack, S., Marx, A., Thormahlen, M., Schonbrunn, E., Biou, V., Thompson, A., Mandelkow, E.-M., and Mandelkow, E. (1997) Cell 91, 985-994.
20. Sablin, E. P., Case, R. B., Dai, S. C., Hart, C. L., Ruby, A., Vale, R. D., and Fletterick, R. J. (1998) Nature 395, 813-816.
21. Sablin, E. P., Kull, F. J., Cooke, R., Vale, R. D., and Fletterick, R. J. (1996) Nature 380, 555-559.
22. Gulick, A. M., Song, H., Endow, S. A., and Rayment, I. (1998) Biochemistry 37, 1769-1777.
23. Kull, F. J., Vale, R. D., and Fletterick, R. J. (1998) J. Muscle Res. Cell Motil. 19, 877-886.
24. Vale, R. D. (1996) J. Cell Biol. 135, 291-302.
25. Woehlke, G., Ruby, A. K., Hart, C. L., Ly, B., Hom-Booher, N., and Vale, R. D. (1997) Cell 90, 207-216.
26. Hiratsuka, T. (1983) Biochim. Biophys. Acta 742, 596-508.
27. Case, R. B., Pierce, D. W., Hom-Booher, N., Hart, C. L., and Vale, R. D. (1997) Cell 90, 959-966.
28. Pierce, D. W., and Vale, R. D. (1998) Methods Enzymol. 298, 154-171.
29. Press, W. H., Teukolsky, S. A., Vetterling, W. T., and Flannery, B. P. (1992) Numerical recipes in C, 2nd ed., Cambridge University Press, Cambridge, U.K.
30. Sosa, H., Dias, P., Hoenger, A., Whittaker, M., Wilson-Kubalek, E., Sablin, E., Fletterick, R. J., Vale, R. D., and Milligan, R. A. (1997) Cell 90, 217-224.
31. Rice, S., Lin, A. W., Safer, D., Hart, C. L., Naber, N., Carragher, B. O., Cain, S. M., Pechatnikova, E., Wilson-Kubalek, E. M., Whittaker, M., Pate, E., Cooke, R., Taylor, E. W., Milligan, R. A., and Vale, R. D. (1999) Nature 402, 778-784.
32. Ma, Y. Z., and Taylor, E. W. (1995) Biochemistry 34, 13233-13241.
33. Cheng, J.-Q., Jiang, W., and Hackney, D. D. (1998) Biochemistry 37, 5288-5295.
34. Hackney, D. D., Malik, A. S., and Wright, K. W. (1989) J. Biol. Chem. 264, 15943-15948.
35. Sadhu, A., and Taylor, E. W. (1992) J. Biol. Chem. 267, 11352-11359.
36. Gilbert, S. P., and Johnson, K. A. (1994) Biochemistry 33, 1951-1960.
37. Lockhart, A., Cross, R. A., and McKillop, D. F. (1995) FEBS Lett. 368, 531-535.
38. Romberg, L., Pierce, D. W., and Vale, R. D. (1998) J. Cell Biol. 140, 1407-1416.
39. Matthews, B. W. (1996) FASEB J. 10, 35-41.
40. Sondek, J., Lambright, D. G., Noel, J. P., Hamm, H. E., and Sigler, P. B. (1994) Nature 372, 276-279.
41. Coleman, D. E., Berghuis, A. M., Lee, E., Linder, M. E., Gilman, A. G., and Sprang, S. R. (1994) Science 265, 1405-1412.
42. Ruppel, K. M., and Spudich, J. A. (1996) Mol. Biol. Cell 7, 1123-1136.
43. Case, R. B., Rice, S., Hart, C. L., Ly, B., and Vale, R. D. (2000) Curr. Biol. 10, 157-160.
44. Lambright, D. G., Noel, J. P., Hamm, H. E., and Sigler, P. B. (1994) Nature 369, 621-628.
45. Pierce, D. W., Hom-Booher, N., Otsuka, A. J., and Vale, R. D. (1999) Biochemistry 38, 5412-5421.