P-selectin blockade following fluid-percussion injury: Behavioral and immunochemical sequelae

Journal of Neurotrauma

Volumn 16, Issue 1, 1999, Pages 13-25

  Grady, M Sean ^a,b   Cody Jr , Richard F ^a   Maris, Donald O ^a   McCall, Todd D ^a   Seckin, Hakan ^a   Sharar, Sam R ^a   Winn, H Richard ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b Box 359766 ^*  (United States)

Author keywords

Cell adhesion molecule; Fluid percussion injury; Morris water maze; Neuroprotection; Neutrophil migration; P selectin; Rats

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; GLIAL FIBRILLARY ACIDIC PROTEIN; MONOCLONAL ANTIBODY; PADGEM PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; IMMUNOHISTOCHEMISTRY; IMMUNOREGULATION; INFLAMMATORY INFILTRATE; LEUKOCYTE MIGRATION INHIBITION; MALE; MAZE TEST; NEUROPROTECTION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PATHOPHYSIOLOGY; RAT; TASK PERFORMANCE; TREATMENT OUTCOME;

EID: 0032890908     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.1999.16.13     Document Type: Article

References (59)

1. AIHARA, N., HALL, J.J., PITTS, L.H., FUKUDA, K., and NOBLE, L.J. (1995). Altered immunoexpression of microglia and macrophages after mild head injury. J. Neurotrauma 12, 53-63.
2. ALBELDA, S.M., SMITH, S.W., and WARD, P.A. (1994). Adhesion molecules and inflammatory injury. F.A.S.E.B. J. 8, 504-512.
3. ARSENIO-NUNES, M.L., HOSSMAN, K.A., and FARKAS-BARGETON, E. (1973). Ultrastructural and histochemical investigation of the cerebral cortex of cat during and after complete ischaemia. Acta Neuropathol. (Berl.) 26, 329-344.
4. BEVILACQUA, M.P., and NELSON, R.M. (1993). Selectins. J. Clin. Invest. 91, 379.
5. BIAGAS, K.V., UHL, M.W., SCHIDING, J.K., NEMOTO, E.M., and KOCHANEK, P.M. (1992). Assessment of post-traumatic polymorphonuclear leukocyte accumulation in rat brain using tissue myeloperoxidase assay and vinblastine treatment. J. Neurotrauma 9, 363-371.
6. BRAUGHLER, JM., HALL, E.D., MEANS, E.D., WATERS, T.R., and ANDERSON, D.K. (1987). Evaluation of an intensive methylprednisolone sodium succinate dosing regimen in experimental spinal cord injury. J. Neurosurg. 67, 102-105.
7. CAO, W., CARNEY, J.M., DUCHON, A., FLOYD, R.A., and CHEVION, M. (1988). Oxygen free radical involvement in ischemia and reperfusion injury to brain. Neurosci. Lett. 88, 233-238.
8. CARLOS, T.M., CLARK, R.S.B., FRANCIOLA-HIGGINS, D., SCHIDING, J.K., and KOCHANEK, P.M. (1997). Expression of endothelial adhesion molecules and recruitment of neutrophils after traumatic brain injury in rats. J. Leukoc. Biol. 61, 279-285.
9. CARLOS, T.M., and HARLAN, J.M. (1994). Leukocyte-endothelial adhesion molecules. Blood 84, 2068-2101.
10. CHAN, P.H., LONGAR, S., and FISHMAN, R.A. (1987). Protective effects of liposome-entrapped superoxide dismutase on posttraumatic brain edema. Ann. Neurol 21, 540-547.
11. CHIANG, J., KOWADA, M., AMES, A. III, WRIGHT, R.L., and MAJNO, G. (1968). Cerebral ischemia: vascular changes. Am. J. Pathol. 52, 455-476.
12. CLARK, R.S., SCHIDING, J.K., KACZOROWSKI, S.L., MARION, D.W., and KOCHANEK, P.M. (1994). Neutrophil accumulation after traumatic brain injury in rats: comparison of weight drop and controlled cortical impact models. J. Neurotrauma 11, 499-506.
13. CLIFTON, G.L., JIANG, J.Y., LYETH, B.C., JENKINS, L.W., HAMM, R.J., and HAYES, R.L. (1991). Marked protection by moderate hypothermia after experimental traumatic brain injury. J. Cereb. Blood Flow Metab. 11, 114-121.
14. CODY, R.F., MARIS, D.O., and GRADY, M.S. (1995). Single-day testing in the Morris water maze. Soc. Neurosci. Abst. 21, 1731.
15. CORTEZ, S.C., McINTOSH, T.K., and NOBLE, L.J. (1989). Experimental fluid percussion brain injury: vascular disruption and neuronal and glial alterations. Brain Res. 482, 271-282.
16. DAVENPECK, K.L., GAUTHIER, T.W., ALBERTINE, K.H., and LEFER, A.M. (1994). Role of P-selectin in microvascular leukocyte-endothelial interaction in splanchnic ischemia-reperfusion. Am. J. Physiol. 267, H622-H630.
17. DUSTIN, M.L., ROTHLEIN, R., BHAN, A.K., DINARELL, C.A., and SPRINGER, T.A. (1986). Induction by IL-1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J. Immunol. 137, 245-254.
18. GIBBS, S.A., WEISER, M.R., KOBZIK, L., VALERI, C.R., SHEPRO, D., and HECHTMAN, H.B. (1996). P-selectin mediates intestinal ischemic injury by enhancing complement deposition. Surgery 119, 652-656.
19. GNAHN, H., HEFTI, F., HEUMANN, R., SCHWAB, M.E., and THOENEN, H. (1983). NGF-mediated increase of choline acetyltransferase (ChAT) in the neonatal rat forebrain: evidence for a physiological role of NGF in the brain? Dev. Brain Res. 9, 45-52.
20. GRAMMAS, P., LIU, G.J., WOOD, K., and FLOYD, R.A. (1993). Anoxia/reoxygenation induces hydroxyl free radical formation in brain microvessels. Free Radic. Biol. Med. 14, 553-557.
21. GRUNDL, P.D., BIAGAS, K.V., KOCHANEK, P.M., SCHIDING, J.K., BARMADA, M.A., and NEMOTO, E.M. (1994). Early cerebrovascular response to head injury in immature and mature rats. J. Neurotrauma 11, 135-148.
22. HAMM, R.J., DIXON, C.E., GBADEBO, D.M., et al. (1992). Cognitive deficits following traumatic brain injury produced by controlled cortical impact. J. Neurotrauma 9, 11-20.
23. HARLAN, J.M., WINN, R.K., VEDDER, N.B., DOERSCHUK, C.M., and RICE, C.L. (1992). In vivo models of leukocyte adherence to endothelium, in: Adhesion: Its Role in Inflammatory Disease. J.M. Harlan and D.Y. Liu (eds), W.H. Freeman: New York, pps. 117-150.
24. HERNANDEZ, L.A., GRISHAM, M.B., TWOHIG, B., ARFORS, K.E., HARLAN, J.M., and GRANGER, D.N. (1987). Role of neutrophils in ischemia-reperfusion-induced microvascular injury. Am. J. Physiol. 253, H699-H703.
25. HICKS, R.R., SMITH, D.H., LOWENSTEIN, D.H., SAINT MARIE, R.L., and McINTOSH, T.K. (1993). Mild experimental brain injury in the rat induces cognitive deficits associated with regional neuronal loss in the hippocampus. J. Neurotrauma 10, 405-414.
26. JIANG, J.Y., LYETH, B.G., CLIFTON, G.L., JENKINS, L.W., HAMM, R.J., and HAYES, R.H. (1991). Relationship between body and brain temperature in traumatically brain-injured rodents. J. Neurosurg. 74, 492-496.
27. KACZOROWSKI, S.L., SCHIDING, J.K., TOTH, C.A., and KOCHANEK, P.M. (1995). Effect of soluble complement receptor-1 on neutrophil accumulation after traumatic brain injury in rats. J. Cereb. Blood Flow Metab. 15, 860-864.
28. KOCHANEK, P.M. (1993). Ischemic and traumatic brain injury: pathobiology and cellular mechanisms. Crit. Care Med. 21, S333-S335.
29. KOCHANEK, P.M., and HALLENBECK, J.M. (1992). Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke. Stroke 23, 1367-1379.
30. LASKY, L.A. (1992). Selectins: interpreters of cell-specific carbohydrate information during inflammation. Science 285, 964.
31. LEONARD, J.R., GRADY, M.S., LEE, M.E., PAZ, J.C., and WESTRUM, L.E. (1997). Fluid percussion injury causes disruption of the septohippocampal pathway in the rat. Exp. Neurol. 143, 177-187.
32. LEONARD, J.R., MARIS, D.O., and GRADY, M.S. (1994). Fluid percussion injury causes loss of forebrain choline acetyltransferase and nerve growth factor receptor immunoreactive cells in the rat. J. Neurotrauma 11, 379-392.
33. LEVIN, H.S., GROSSMAN, R.G., ROSE, J.E., and TEASDALE, G. (1979). Long-term neuropsychological outcome of closed head injury. J. Neurosurg. 50, 412-422.
34. LOWENSTEIN, D.H., THOMAS, M.J., SMITH, D.H., and McINTOSH, T.K. (1992). Selective vulnerability of dentate hilar neurons following traumatic brain injury: a potential mechanistic link between head trauma and disorders of the hippocampus. J. Neurosci. 12, 4846-4853.
35. MARTY, S., DUSART, I., and PESHANSKI, M. (1991). Glial changes following an excitotoxic lesion in the CNS. I. Microglia/macrophages. Neuroscience 45, 529-539.
36. MATSUO, Y., ONODERA, H., SHIGA, Y., et al. (1994). Correlation between myeloperoxidase-quantified neutrophil accumulation and ischemic brain injury in the rat: effects of neutrophil depletion. Stroke 25, 1469-1475.
37. McINTOSH, T.K., VINK, R., NOBLE, L., et al. (1989). Traumatic brain injury in the rat: characterization of a lateral fluid-percussion model. Neuroscience 28, 233-244.
38. MOREHEAD, M., BARTUS, R.T., DEAN, R.L., et al. (1994). Histopathologic consequences of moderate concussion in an animal model: correlations with duration of unconsciousness. J. Neurotrauma 11, 657-667.
39. MORRIS, R.G.M., GARRUD, P., RAWLINS, J.N.P., and O'KEEFE, J. (1982). Place navigation impaired in rats with hippocampal lesions. Nature 297, 681-683.
40. MULLIGAN, M.S., POLLEY, M.J., BAYER, R.J., NUNN, M.F., PAULSON, J.C., and WARD, P.A. (1992). Neutrophil-dependent acute lung injury: requirement for P-selectin (GMP-140). J. Clin. Invest. 90, 1600-1607.
41. OKADA, Y., COPELAND, B.R., MORI, E., TUNG, M.-M., THOMAS, W.S., and DEL ZOPPO, G.J. (1994). P-selectin and intercellular adhesion molecule-1 expression after focal brain ischemia and reperfusion. Stroke 25, 202-211.
42. OLIVER, C.N., STARKE-REED, P.E., STADTMAN, E.R., LIU, G.J., CARNEY, J.M., and FLOYD, R.A. (1990). Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain. Proc. Natl. Acad. Sci. U.S.A. 87, 5144-5147.
43. POBER, J.S., and COTRAN, R.S. (1990). Cytokines and endothelial cell biology. Physiol. Rev. 70, 427-451.
44. ROSOMOFF, R.L., CLASEN, R.A., HARTSTOCK, R., and BEBIN, J. (1965). Brain reaction to experimental injury after hypothermia. Arch. Neurol. 13, 337-344.
45. SCHOETTLE, R.J., KOCHANEK, P.M., MAGARGEE, M.J., UHL, M.W., and NEMOTO, E.M. (1990). Early polymorphonuclear leukocyte accumulation correlates with the development of posttraumatic cerebral edema in rats. J. Neurotrauma 7, 207-217.
46. SEEKAMP, A., TILL, G.O., MULLIGAN, M.S., et al. (1994). Role of selectins in local and remote tissue injury following ischemia and reperfusion. Am. J. Pathol. 144, 592-598.
47. SHARAR, S.R., SASAKI, S.S., FLAHERTY, L.C., PAULSON, J.C., HARLAN, J.M., and WINN, R.K. (1993). P-selectin blockade does not impair leukocyte host defense against bacterial peritonitis and soft tissue infection in rabbits. J. Immunol. 151, 4982-4988.
48. SHOHAMI, E., SHAPIRA, Y., YADID, G., REISFELD, N., and YEDGAR, S. (1989). Brain phospholipase A2 is activated after experimental closed head injury in the rat. J. Neurochem. 53, 1541-1546.
49. SIESJO, B.K. (1988). Mechanisms of ischemic brain damage. Crit. Care Med. 16, 954-963.
50. SMITH, D.H., LOWENSTEIN, D.H., GENNARELLI, T.A., and McINTOSH, T.K. (1994). Persistent memory dysfunction is associated with bilateral hippocampal damage following experimental brain injury. Neurosci. Lett. 168, 151-154.
51. SOARES, H.D., HICKS, R.R., SMITH, D., and McINTOSH, T.K. (1995). Inflammatory leukocytic recruitment and diffuse neuronal degeneration are separate pathological processes resulting from traumatic brain injury. J. Neurosci. 15, 8223-8233.
52. TOULMOND, S., and ROTHWELL, N.J. (1995). Interleukin-1 receptor antagonist inhibits neuronal damage caused by fluid percussion injury in the rat. Brain Res. 671, 261-266.
53. UHL, M.W., BIAGAS, K.V., GRUNDL, P.D., et al. (1994). Effects of neutropenia on edema, histology, and cerebral blood flow after traumatic brain injury in rats. J. Neurotrauma 11, 303-315.
54. WEISER, M.R., GIBBS, S.A.L., VALERI, C.R., SHEPRO, D., and HECHTMAN, H.B. (1996). Anti-selectin therapy modifies skeletal muscle ischemia and reperfusion injury. Shock 5, 402-407.
55. WHALEN, M.J., CARLOS, T.M., CLARK, R.S.B., et al. (1997). The effect of brain temperature on acute inflammation after traumatic brain injury in rats. J. Neurotrauma 14, 561-572.
56. WHALEN, M.J., CARLOS, T.M., KOCHANEK, P.M., BELL, M.J., CARCILLO, J.A., and ADELSON, P.D. (1997). Soluble P-selectin is increased in CSF in children with severe head injury. J. Cereb. Blood Flow Metab. 17, S77.
57. WINN, R.K., LIGGITT, D., VEDDER, N.B., PAULSON, J.C., and HARLAN, J.M. (1993). Anti-P-selectin monoclonal antibody attenuates reperfusion injury to the rabbit ear. J. Clin. Invest. 92, 2042-2047.
58. WINN, R.K., PAULSON, J.C., and HARLAN, J.M. (1994). A monoclonal antibody to P-selectin ameliorates injury associated with hemorrhagic shock in rabbits. Am. J. Physiol. 267, H2391-H2397.
59. ZIMMERMAN, J. (1986). Polymorphonuclear leukocytes -agents of host defense and autoinjury, in: Critical Care State of the Art. B. Chernow and S. Shoemaker (eds), Society of Critical Care Medicine: Fullerton, CA, pps. 281-299.