Eicosanoid mediator expression in mononuclear and polymorphonuclear cells in normal subjects and patients with atopic asthma and cystic fibrosis

Thorax

Volumn 51, Issue 12, 1996, Pages 1223-1228

  Kuitert, L M ^a   Newton, R ^a   Barnes, N C ^b   Adcock, I M ^a   Barnes, P J ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b LONDON CHEST HOSPITAL   (United Kingdom)

Author keywords

asthma; cystic fibrosis; eicosanoids; leukotrienes

Indexed keywords

ICOSANOID; LEUKOTRIENE; STEROID;

ADULT; ARTICLE; ASTHMA; CLINICAL ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; INHALATIONAL DRUG ADMINISTRATION; MALE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION;

EID: 0029843321     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.51.12.1223     Document Type: Article

References (33)

1. Lewis RA, Austen KF, Soberman RJ. Leukotrienes and other products of the 5-lipoxygenase pathway. N Engl J Med 1990;323:645-55.
2. Arm JP, Lee TH. Sulphidopeptide leukotrienes in asthma (editorial review). Clin Sci 1993;84:501-10.
3. O'Banion MK, Winn VD, Young DA. cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase. Proc Natl Acad Sci USA 1992; 89:4888-92.
4. Mitchell JA, Larkin S, Williams TJ. Cyclooxygenase-2: regulation and relevance in inflammation. Biochem Pharmacol 1995;50:1535-42.
5. Christie PE, Spur BW, Lee TH. The effects of lipoxin A4 on airway responses in asthmatic subjects. Am Rev Respir Dis 1992;145:1281-4.
6. Serhan CN. Lipoxin biosynthesis and its impact in inflammatory and vascular events. Biochim Biophys Acta 1994;1212:1-25.
7. Fischer DB, Christman JW, Badr KF. Fifteen-S-hydroxyeicosatetraenoic acid (15-S-HETE) specifically antagonises the chemotactic action and glomerular synthesis of leukotriene B4 in the rat. Kidney Int 1992;41:1155-60.
8. Serhan CN. Lipoxins: eicosanoids carrying intra- and intercellular messages. J Bioenerg Biomembr 1991;23:105-22.
9. Miadonna A, Tedeschi A, Brasca C, Folco G, Sala A, Murphy RC. Mediator release after endobronchial antigen challenge in patients with respiratory allergy. J Allergy Clin Immunol 1990;85:906-13
10. Sampson AP, Green CP, Spencer DA, Piper PJ, Price JF. Leukotrienes in the blood and urine of children with acute asthma. Ann NY Acad Sci 1991;629:437-9.
11. Sampson AP, Thomas RU, Costello JF, Piper PJ. Fnhanced leukotriene synthesis in leukocytes of atopic and asthmatic subjects. Br J Clin Pharmacol 1992;33:423-30.
12. Lee TH, Crea AEG, Gant V, Spur BW, Marron BE, Nicolaou KC, et al. Identification of lipoxin A4 and its relationship to the sulfidopeptide leukotrienes C4, D4, and E4 in the bronchoalveolar lavage fluids obtained from patients with selected pulmonary diseases. Am Rev Respir Dis 1990;141:1453-8.
13. Israel E, Rubin P, Kemp JP, Grossman J, Pierson W, Siegel SC, et al. The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma. Ann Intern Med 1994;119:1059-66.
14. Gough NM. Rapid and quantitative preparation of cytoplasmic RNA from small numbers of cells. Anal Biochem 1988;173:93-5.
15. Bennett CF, Chiang M-Y, Monia BP, Crooke ST. Regulation of 5-lipoxygenase and 5-lipoxygenase activating protein expression in HL-60 cells. Biochem J 1993;289:33-9.
16. Kargman S, Rouzer CA. Studies on the regulation, biosynthesis, and activation of 5-lipoxygenase in differentiated HL60 cells. J Biol Chem 1989;264:13313-20.
17. Malaviya R, Jakschik BA. Reversible translocation of 5-lipoxygenase in mast cells upon IgE/antigen stimulation. J Biol Chem 1993;268:4939-44.
18. Coffey MJ, Wilcoxen SE, Peters-Golden M. Increases in 5-lipoxygenase activating protein account for enhanced capacity for 5-lipoxygenase metabolism that accompanies differentiation of peripheral blood munocytes into alveolar macrophages. Am J Respir Cell Mol Biol 1994;11:153-8.
19. Pueringer RJ, Bahns CC, Hunninghake GW. Alveolar macrophages have greater amounts of the enzyme 5-lipoxygenase than do monocytes. J Appl Physiol 1992;73: 781-6.
20. Bigby TD, Holrzman MJ. Enhanced 5-lipoxygenase activity from lung macrophages compared to monocytes from normal subjects. J Immunol 1987;138:1546-50.
21. Zakrzewski JT, Barnes NC, Piper PJ, Costello JE. Detection of sputum eicosanoids in cystic fibrosis and in normal saliva by bioassay and rudioimmunoassay. Br J Pharmacol 1987;23:19-27.
22. Sampson AP, Spencer DA, Green CP, Piper PJ, Price JF. Leukotrienes in the sputum and urine of cystic fibrosis children. Br J Clin Pharmacol 1990;30:861-9.
23. Lin AL, Bienkowski MJ, Gorman RR. Regulation of prostaglandin H synthase mRNA levels and prostaglandin biosynthesis by platelet-derived growth factor. J Biol Cham 1989;264:17379-83.
24. Ali A, Ford-Hutchinson AW, Nicholson DW. Activation of protein kinase C down-regulates leukotriene CA synthase activity and attenuates cysteinyl leukotriene production in un eosinophilic substrain of HL-60 cells. J Immunol 1994; 153:776-88.
25. Hempel SL, Monik MM, Hunninghake GW. Lipopolysaccharide induces prostaglandin H synthase-2 protein and mRNA in human alveolar macrophages and blood monocytes. J Clin Invest 1994;93:391-6.
26. Sigal E. The molecular biology of mammalian arachidonic acid metabolism. Am J Physiol 1991;260:L13-28.
27. Nadel JA, Conrad DJ, Ueki IF, Schuster A, Sigal E. Immunocytochemical localisation of arachidonate 15-lipoxygenase in erythrocytes, leukocytes, and airway cells. J Clin Invest 1991;87:1139-45.
28. Conrad DJ, Kuhn H, Mulkins M, Highland E, Sigal E. Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase. Proc Natl Acad Sci USA 1992;89:217-21.
29. Nassar GM, Morrow JD, Roberts II LJ, Lakkis FG, Badr KF. Induction of 15-lipoxygenase by interleukin-13 in human blood monocytes. J Biol Chem 1994;269:27631-4.
30. Sigal E, Conrad DJ. Human 15-lipoxygenase: a potential effector molecule for interleukin-4. Adv Prostaglandin Thromboxane Leukot Res 1994;22:309-16.
31. Shannon VR, Chanez P, Bousquet J, Holtzman MJ. Histochemical evidence for induction of arachidonate 15-lipoxygenase in airway disease. Am Rev Respir Dis 1993;147: 1024-8.
32. Badr KF. 15-lipoxygenase products as leukotriene antagonists: therapeutic potential in glomerulonephritis. Kidney Int 1992;42(Suppl 38):S101-8.
33. Bonfield TL, Konstan MW, Burfeind P, Panuska JR, Milliard JB, Berger M. Normal bronchial epithelial cells constitutively produce the anti-inflammatory cytokine interleukin-10, which is downregulated in cystic fibrosis. Am J Respir Cell Mol Biol 1995;13:257-61.