Molecular basis of ligand recognition by integrin α5β1. II. Specificity of Arg-Gly-Asp binding is determined by Trp157 of the α subunit

Journal of Biological Chemistry

Volumn 275, Issue 27, 2000, Pages 20337-20345

  Humphries, Jonathan D ^a   Askari, Janet A ^a   Zhang, Xi Ping ^b   Takada, Yoshi ^b   Humphries, Martin J ^a   Mould, A Paul ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; CYCLOPEPTIDE; EPITOPE; INTEGRIN; MONOCLONAL ANTIBODY; PROTEIN SUBUNIT; TRYPTOPHAN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE;

ANIMALS; ANTIBODIES, MONOCLONAL; BINDING SITES; CELL ADHESION; CHO CELLS; CRICETINAE; HUMANS; LIGANDS; MUTATION; OLIGOPEPTIDES; PROTEIN BINDING; RECEPTORS, FIBRONECTIN; SUBSTRATE SPECIFICITY; TRYPTOPHAN;

EID: 0034617222     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M000568200     Document Type: Article

References (54)

1. Hynes, R. O. (1992) Cell 69, 11-25
2. Springer, T. A. (1994) Cell 76, 301-316
3. Fernandez, C., Clark, K., Burrows, L., Schofield, N. R., and Humphries, M. J. (1998) Front. Biosci. 3, 684-700
4. Aota, S., Nomizu, M., and Yamada, K. M. (1994) J. Biol. Chem. 269, 24756-24761
5. Bowditch, R. D., Hariharan, M., Tominna, E. F., Smith, J. W., Yamada, K. M., Getzoff, E. D., and Ginsberg, M. H. (1994) J. Biol. Chem. 269, 10856-10863
6. Tan, K., Casasnovas, J. M., Liu, J., Briskin, M. J., Springer, T. A., and Wang, J. (1998) Structure 6, 793-801
7. Kraft, S., Diefenbach, B., Mehta, R., Jonczyk, A., Luckenbach, G. A., and Goodman, S. (1999) J. Biol. Chem. 274, 1979-1985
8. Koivunen, E., Gay, D., and Ruoslahti, E. (1993) J. Biol. Chem. 268, 20205-20210
9. Koivunen, E., Wang, B., and Ruoslahti, E. (1994) J. Cell Biol. 124, 373-380
10. Koivunen, E., Wang, B., and Ruoslahti, E. (1995) Bio/Technology 13, 265-270
11. Tuckwell, D. S., Brass, A. M., and Humphries, M. J. (1992) Biochem. J. 285, 325-331
12. Diamond, M. S., Garcia-Aguilar, J., Bickford, J. K., Corbi, A. L., and Springer, T. A. (1993) J. Cell Biol. 120, 1031-1043
13. Humphries, M. J., and Newham, P. (1998) Trends Cell Biol. 8, 78-83
14. Takada, Y., Kamata, T., Irie, A., Puzon-McLaughlin, W., and Zhang, X-P. (1997) Matrix Biol. 16, 143-151
15. Springer, T. A. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 65-72
16. Irie, A., Kamata, T., Puzon-McLaughlin, W., and Takada, Y. (1995) EMBO J. 14, 5550-5556
17. Irie, A., Kamata, T., and Takada, Y. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 7198-7203
18. Mould, A. P., Askari, J. A., Aota, S., Yamada, K. M., Irie, A., Takada, Y., Harden, H. J., and Humphries, M. J. (1997) J. Biol. Chem. 272, 17283-17292
19. Krukonis, E. S., Dersch, P., Eble, J. A., and Isberg, R. (1998) J. Biol. Chem. 273, 31837-31843
20. Mould, A. P., Burrows, L., and Humphries, M. J. (1998) J. Biol. Chem. 273, 25664-25672
21. Lee, O.-J., Rieu, P., Arnaout, M. A., and Liddington, R. (1995) Cell 80, 631-638
22. Tozer, E. C., Liddington, R. C., Sutcliffe, M. J., Smeeton, A. H., and Loftus, J. C. (1996) J. Biol. Chem. 271, 21978-21984
23. Tuckwell, D. S., and Humphries, M. J. (1997) FEBS Lett. 400, 297-303
24. Puzon-McLaughlin, W., and Takada, Y. (1996) J. Biol. Chem. 271, 20438-20443
25. Goodman, T. G., and Bajt, M. L. (1996) J. Biol. Chem. 271, 23729-23736
26. Lin, E. C. K., Ratnikov, B. I., Tsai, P. M., Gonzalez, E. R., McDonald, S., Pelletier, A. J., and Smith, J. W. (1997) J. Biol. Chem. 272, 14236-14243
27. Tam, J. P., Wu, C-R., Liu, W., and Zhang, J-W. (1991). Am. Chem. Soc. 113, 6657-6662
28. Mould, A. P., Akiyama, S. K., and Humphries, M. J. (1996) J. Biol. Chem. 271, 20365-20374
29. Danen, E. H. J., Aota, S., van Kraats, A. A., Yamada, K. M., Riuter, D. J., and van Muijen G. N. P. (1995) J. Biol. Chem. 270, 21612-21618
30. Mould, A. P., Akiyama, S. K., and Humphries, M. J. (1995) J. Biol. Chem. 270, 26270-26277
31. Burrows, L., Clark, K., Mould, A. P., and Humphries, M. J. (1999) Biochem. J. 344, 527-533
32. Schreiner, C. L., Bauer, J. S., Danilov, Y. N., Hussein, S., Sczekan, M., and Juliano, R. L. (1989) J. Cell Biol. 109, 3157-3167
33. Mahler, H. R., and Cordes, E. H. (1966) Biological Chemistry, pp. 250-253, Harper and Row, New York
34. Müller, B., Zerwes, H.-G., Tangemann, K., Peter, J., and Engel, J. (1993) J. Biol. Chem. 268, 6800-6808
35. Kuijpers, T. W., Mul, E. P., Blom, M., Kovach, N., Gaeta, F. C. A., Tollefson, V., Elices, M. J., and Harlan, J. M. (1993) J. Exp. Med. 178, 279-284
36. Clackson, T., and Wells, J. A. (1995) Science 267, 383-386
37. McGaughey, G. B., Gagné, M., and Rappe, A. K. (1998) J. Biol. Chem. 273, 15458-15463
38. Bogan, A. A., and Thorn, K. S. (1998) J. Mol. Biol. 280, 1-9
39. Ruoslahti, E. (1996) Ann. Rev. Cell Dev. Biol. 12, 697-715
40. D'Souza, S. E., Ginsberg, M. H., Burke, T. A., Lam, S. C. T., and Plow, E. F. (1988) Science 242, 91-93
41. Smith, J. W., and Cheresh, D. A. (1988) J. Biol. Chem. 263, 18726-18731
42. Takada, Y., and Puzon, W. (1993) J. Biol. Chem. 268, 17597-17601
43. Shih, D.-T., Boettiger, D., and Buck, C. A. (1997) J. Cell Sci. 110, 2619-2628
44. Bitan, G., Schleiber, L., Greenberg, Z., Rosenblatt, M., and Chorev, M. (1999) Biochemistry 38, 3414-3420
45. Cierniewski, C. S., Byzova, T., Papierak, M., Haas, T., Niewiarowska, J., Zhang, L., Cieslak, M., and Plow, E. F. (1999) J. Biol. Chem. 274, 16923-16932
46. Bajt, M. L., and Loftus, J. C. (1994) J. Biol. Chem. 269, 20913-20919
47. Loftus, J. C., and Liddington, R. C. (1997) J. Clin. Invest. 99, 2302-2306
48. Mould, A. P., Garratt, A. N., Puzon-McLaughlin, W., Takada, Y., and Humphries, M. J. (1998) Biochem. J. 331, 821-828
49. Mould, A. P., Askari, J. A., and Humphries, M. J. (2000) J. Biol. Chem. 275, 20324-20336
50. Zhang, X.-P., Puzon-McLaughlin, W., Irie, A., Kovach, N., Prokopishyn, N. L., Laferte, S., Takeuchi, K., Tsuji, T., and Takada, Y. (1999) Biochemistry 38, 14424-14431
51. Honda, S., Tomiyama, Y., Shiraga, M., Tadokoro, S., Takamatsu, J., Saito, H., Kurata, Y., and Matsuzawa, Y. (1998) J. Clin. Invest. 102, 1183-1192
52. Takagi, J., Kamata, T., Meredith, J., Puzon-McLaughlin, W., and Takada, Y. (1997) J. Biol. Chem. 272, 19794-19800
53. Lin, E. C. K., Ratnikov, B. I., Tsai, P. M., Carron, C. P., Myers, D. M., Barbas, C. F., III, and Smith, J. W. (1997) J. Biol. Chem. 272, 23912-23920
54. Curley, G. P., Blum, H., and Humphries, M. J. (1999) Cell. Mol. Life Sci. 56, 427-441