Improving lipase enantioselectivity in organic solvents by forming substrate salts with chiral agents

Biotechnology and Bioengineering

Volumn 69, Issue 5, 2000, Pages 577-583

  Shin, Jong Shik ^a   Luque, Susana ^a   Klibanov, Alexander M ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Enantioselectivity; Lipase; Molecular modeling; Nonaqueous enzymology; Organic solvents; Salts

Indexed keywords

ACETONITRILE; BACTERIA; CATALYST SELECTIVITY; COMPOSITION EFFECTS; MATHEMATICAL MODELS; MOLECULAR STRUCTURE; ORGANIC ACIDS; ORGANIC SOLVENTS; SALTS; STEREOCHEMISTRY;

BRONSTED-LOWRY ACID; ENANTIOSELECTIVITY; LIPASE; MANDELIC ACID; PROPANOLYSIS;

ENZYMES;

ACETONITRILE; MANDELIC ACID; ORGANIC SOLVENT; PHENYLALANINE METHYL ESTER; SODIUM CHLORIDE; TRIACYLGLYCEROL LIPASE;

ARTICLE; BURKHOLDERIA CEPACIA; CRYSTALLIZATION; DIASTEREOISOMER; ENANTIOMER; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SPECIFICITY; MOLECULAR MODEL; NONHUMAN; STEREOCHEMISTRY;

BIOTECHNOLOGY; BURKHOLDERIA CEPACIA; LIPASE; MODELS, MOLECULAR; PHENYLALANINE; SALTS; SOLVENTS; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

BURKHOLDERIA; BURKHOLDERIA CEPACIA; FELIS CATUS; PSEUDOMONAS;

EID: 0034609593     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0290(20000905)69:5<577::AID-BIT12>3.0.CO;2-Y     Document Type: Article

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