Effects of retinoic acid on proliferation, phenotype and expression of cyclin-dependent kinase inhibitors in TGF-β1-stimulated rat hepatic stellate cells

World Journal of Gastroenterology

Volumn 6, Issue 6, 2000, Pages 819-823

  Huang, G C ^a   Zhang, J S ^a   Zhang, Y E ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; MESSENGER RNA; RETINOIC ACID; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; IN SITU HYBRIDIZATION; LIVER FIBROSIS; MALE; MOLECULAR DYNAMICS; NONHUMAN; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; STELLATE CELL; TRANSCRIPTION REGULATION;

EID: 0034529939     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v6.i6.819     Document Type: Article

References (58)

1. Nonalcoholic steatohepatitis
2. Molecular mechanisms of hepatic fibrosis and principles of therapy
3. Molecular mechanisms in the reversible regulation of morphology, proliferation and collagen metabolism in hepatic stellate cells by the three-dimensional structure of the extracellular matrix
4. Signal transduction in hepatic stellate cells
5. Molecular regulation of hepatic fibrogenesis
6. Cytokines and fibrogenesis
7. Chronic alcohol intake interferes with retinoid metabolism and signaling
8. Diminished retinoic acid signaling in hepatic stellate cells in cholestatic liver fibrosis
9. Retinoid signaling in liver and hepatic fibrosis
10. Perisinusoidal stellate cells of the liver: Important roles in retinol metabolism and fibrosis
11. Novel insights into the biology and physiology of the Ito cell
12. Transdifferentiation of hepatic stellate cells (Ito cells) to myofibroblasts: A key event in hepatic fibrogenesis
13. The cellular basis of hepatic fibrosis
14. Tissue distribution, quantitation and proliferation kinetics of fat-storing cells in carbon tetrachloride-injured rat liver
15. Hepatic fibrogenesis: The puzzle of interacting cells, fibrogenic cytokines, regulatory loops, and extracellular matrix molecules
16. Pathogenesis of liver fibrosis
17. Retinol uptake and metabolism, and cellular retinol binding protein expression in an in vitro model of hepatic stellate cells
18. Retinol and extracellular collagen matrices modulate hepatic Ito cell collagen phenotype and cellular retinol binding protein levels
19. Retinoic acid and transforming growth factor β differentially inhibit platelet-derived-growth-factor-induced Ito-cell activation
20. The effect of retinol on Ito cell proliferation in vitro
21. Retinoic acid suppresses the response to platelet-derived growth factor in human hepatic Ito-cell-like myofibroblasts: A post-receptor mechanism independent of raf / fos / jun / egr activation
22. Retinoic acid modulates rat Ito cell proliferation, collagen, and transforming growth factor β production
23. Retinol esterification activity contributes to retinol transport in stellate cells
24. 4-induced hepatic inflammation and fibrosis in rats
25. Regulation of differentiated phenotype of rat hepatic lipocytes by retinoids in primary culture
26. Ito cell expression of a nuclear retinoic acid receptor
27. The effect of retinoic acid on Ito cell proliferation and content of DNA and RNA
28. Modulation of p53, WAF1/ p21 and BCL-2 expression during retinoic acid-induced differentiation of NB4 promyelocytic cells
29. Retinoids irreversibly inhibit in vitro growth of Epstein-Barr virus-immortalized B lymphocytes
30. WAF1/CIP1 gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation
31. Changes in expression of cell cycle regulators and their hepatic lobular distribution in partial hepatectomy-induced regenerating rat liver
32. Activation of cdk4 and cdk2 during rat liver regeneration is associated with intranuclear rearrangements of cyclin-cdk complexes
33. Regulation of expression and activity of distinct pRB, E2F, D-type cyclin, and CKI family members during terminal differentiation of P19 cells
34. Retinoic acid and the cyclin dependent kinase inhibitors synergistically alter proliferation and morphology of U343 astrocytoma cells
35. Retinoic acid inhibition of cell cycle progression in MCF-7 human breast cancer cells
36. p27Kip1: A key mediator of retinoic acid induced growth arrest in the SMS-KCNR human neuroblastoma cell line
37. cdc2 involved in retinoic acid-induced apoptosis in human hepatoma Hep3B cells
38. Expression of cyclins D1, D2 and E correlates with proliferation of rat stellate cells in culture
39. Effects of heparin on the growth, extracellular matrix and matrix metalloproteinase gene expression in rat hepatic stellate cells
40. A new approach for measurement of cytotoxicity using colorimetric assay
41. Immunohistochemical study on myoglobin in electrocution
42. Transforming growth factor-beta gene expression normal and fibrotic rat liver
43. Transforming growth factor-beta (TGF-beta): A key role in liver fibrogenesis
44. The response of rat liver perisinusoidal lipocytes to polypeptide growth regulator changes with their transdifferentiation into myofibroblast-like cells in culture
45. Role of transforming growth factor β1 in the liver cirrhosis
46. Suppression of experimental hepatic fibrosis by administration of vitamin A
47. Altered distribution of the nuclear receptor RARβ accompanies proliferation and differentiation changes caused by retinoic acid in CACO-2 cells
48. Retinoids and their receptors in differentiation, embryogenesis, and neoplasia
49. The effects of Vitamine A on 3T3 cells, liver lipocytes proliferation and procollagen III expression
50. Inhibition of myeloma cell growth by all-trans retinoic acid is associated with upregulation of p21WAF1 and dephosphorylation of the retinoblastoma protein
51. Antiproliferative effects of retinoic acid/interferon in cervical carcinoma cell lines: Cooperative growth suppression of IRF-1 and p53
52. p27Kip1 accumulation is associated with retinoic-induced neuroblastoma differentiation: Evidence of a decreased proteasome-dependent degradation
53. Cyclin D-CDK subunit arrangement is dependent on the availability of competing INK4 and p21 class inhibitors
54. Inhibition of growth of human leukemia cell lines by retrovirally expressed wild-type p16INK4A
55. G1 phase progression: Cycling on cue
56. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/ CDK4
57. Mutation of cell cycle regulators. Biological and clinical implications for human neoplasia
58. Regulation of the human p21/WAF1/ Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members