Changes in expression of cell cycle regulators and their hepatic lobular distribution in partial hepatectomy-induced regenerating rat liver

Journal of Korean Medical Science

Volumn 14, Issue 6, 1999, Pages 635-642

  Jeong, Jin Sook ^a   Lee, Jeong Hee ^a   Kim, Hyeong In ^a   Park, Joo In ^a  

^a Dong A University College of Medicine   (South Korea)

Author keywords

Cyclin dependent kinases; Cyclins; Enzyme inhibitors; Hepatectomy; Liver regeneration

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLINE;

ANIMAL; ARTICLE; CELL CYCLE; CELL CYCLE S PHASE; DRUG ANTAGONISM; FLOW CYTOMETRY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; INTERPHASE; LIVER; LIVER REGENERATION; LIVER RESECTION; MALE; METABOLISM; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; CELL CYCLE; CYCLIN-DEPENDENT KINASES; CYCLINS; FLOW CYTOMETRY; HEPATECTOMY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INTERPHASE; LIVER; LIVER REGENERATION; MALE; RATS; RATS, SPRAGUE-DAWLEY; S PHASE;

EID: 0033256641     PISSN: 10118934     EISSN: None     Source Type: Journal    
DOI: 10.3346/jkms.1999.14.6.635     Document Type: Article

References (31)

1. Steer CJ. Liver regeneration. FASEB J 1995; 9: 1396-400.
2. Higgins GM, Anderson RM. Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal. Arch Pathol 1931; 12: 186-202.
3. Fausto N, Webber EM. Liver regeneration. In The Liver, Biology and Pathobiology. New York: Raven press, 1994: 1059-84.
4. Loyer P, Glaise D, Carious S, Baffet G, Meijer L, Gaguen-Guillouzo C. Expression and activation of CDKs (1 and 2) and cyclins in the cell progression during liver regeneration. J Biol Chem 1994; 269: 2491-500.
5. Goldworthy TL, Goldworthy SM, Sprankle CS, Butterworth BE. Expression of myc, fos and Ha-ras associated with chemically induced cell proliferation in rat liver. Cell Prolif 1994; 27: 269-78.
6. Michalopoulos GK, DeFrances MC. Liver regeneration. Science 1997; 276: 60-6.
7. Pines J. The cell cycle kinases. Sem Cancer Biol 1994; 5: 305-13.
8. Van den Heuval S, Harlow E. Distinct roles for cyclin-dependent kinases in cell cycle control. Science 1993; 262: 2050-4.
9. Draetta G. Mammalian G1 cyclins. Curr Opin Cell Biol 1994; 6: 842-6.
10. King RW, Jackson PK, Kirschner MW. Mitosis in transition. Cell 1994; 79: 563-71.
11. Nurse P. Ordering S phase and M phase in the cell cycle. Cell 1994; 79: 547-50.
12. Sherr CJ. G1 progression; Cycling on cue. Cell 1994; 79: 551-5.
13. Heichman KA, Roberts JM. Rules to replicate by. Cell 1994; 79: 557-62.
14. Hunter T, Pines J. Cyclins and cancer II: Cyclin D and CDK inhibitors come of age. Cell 1994; 79: 573-82.
15. Sherr C, Roberts JM. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev 1995; 9: 1149-63.
16. Peter M, Herkowitz I. Joining the complex; Cyclin-dependent kinase inhibitory proteins and the cell cycle. Cell 1994; 79: 181-4.
17. Grana X, Reddy EP. Cell cycle control in mammalian cells: Role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs). Oncogene 1995; 11: 211-9.
18. Jaumot M, Estanyol JM, Serratosa J, Agel N, Bach O. Activation of Cdk4 and Cdk2 during rat liver regeneration is associated with intranuclear rearrangements of cyclin-cdk complexes. Hepatology 1999; 29; 385-95.
19. Laemmli UK. Cleavage of structural protein during the assembly of the head of bacteriphage T4. Nature 1970; 227: 680-3.
20. Loyer P, Caribou S, Glaise D, Bilodeau M, Baffet G, Guguen-Guillouzo C. Growth factor dependence of progression through G1 and S phase of adult rat hepatocytes in vitro. J Biol Chem 1996; 271: 11484-92.
21. Cho H, Lim IK, Lee JH. Changes in the expression of cell cycle regulators during rat liver regeneration after partial hepatectomy. Exp Mol Med 1996; 28: 187-91.
22. Rininger JA, Goldsworthy TL, Babish JG. Time course comparison of cell-cycle protein expression following partial hepatectomy and WY14,643-induced hepatic cell proliferation in F344 rats. Carcinogenesis 1997; 18: 935-41.
23. Ehrenfried JA, Ko TC, Thompson A, Evers BM. Cell cycle-mediated regulation of hepatic regeneration Surgery 1997; 122: 927-35.
24. Ando K, Griffin JD. CDK4 integrates gronth stimulatory and inhibitory signals during G1 phase of hematopoietic cells. Oncogene 1995; 10: 751-5.
25. Lu XP, Koch KS, Lew DJ, Dulic V, Pines J, Reed SI, Hunter T, Leffert HL. Induction of cyclin mRNA and cyclin associated histone HI kinase during liver regeneration. J Biol Chem 1992; 267: 2841-4.
26. Akbrecht JH, Hu MY, Cerra FB. Distinct patterns of cyclin D1 regulation in models of liver regeneration and human liver. Biophys Res Commun 1995; 209: 648-55.
27. Walker DH, Maller JL. Role of the cyclin A in the dependence of mitosis on completion of DNA replication. Nature 1991; 345: 314-7.
28. Pagano M, Repperkok R, Verde F, Ansorge W, Dreaetta G. Cyclin A is required at two points in the human cell cycle. EMBO J 1992; 11: 961-71.
29. Rosenblatt J, Gu Y, Morgan DO. Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A. Proc Natl Acad Sci USA 1992; 89: 2824-8.
30. Chao Y, Shih YL, Chiu JH, Chau GY, Lui WY, Yang WK, Lee SD, Huang TS. Overexpression of cyclin A but not skp 2 correlates with the tumor relapse of human hepatocellular carcinoma. Cancer Res 1998; 58: 985-90.
31. Hengst L, Dulic V, Slingerland JM, Lees E, Reed SI. A cell cycle-related inhibitor of cyclin-dependent kinases. Proc Natl Acad Sci USA 1994; 91: 5291-5.