Molecular mapping of the physiological cell death process: Mitochondrial events may be disordered

Annals of the New York Academy of Sciences

Volumn 926, Issue , 2000, Pages 142-148

  Floryk, Daniel ^a   Ucker, David S ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

Bcl 2; Caspases; Cytochrome c; Membrane potential; Transient transfection

Indexed keywords

CASPASE; CYTOCHROME C; PROTEIN BCL 2;

CELL DEATH; CONFERENCE PAPER; CYTOFLUOROMETRY; CYTOLOGY; DISSOLUTION; ENZYME ACTIVITY; ENZYME RELEASE; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION;

EID: 0034502268     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2000.tb05608.x     Document Type: Conference Paper

References (23)

1. Caspase-dependent Cdk activity is a requisite effector of apoptotic death events
2. The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
3. Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
4. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
5. Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development
6. Differential requirement for caspase 9 in apoptotic pathways in vivo
7. Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
8. Apaf1 is required for mitochondrial pathways of apoptosis and brain development
9. Commitment and effector phases of the physiological cell death pathway elucidated with respect to Bcl-2, caspase, and cyclin-dependent kinase activities
10. Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis
11. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
12. The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant
13. Mitochondrial depolarization accompanies cytochrome c release during apoptosis in PC6 cells
14. Simultaneous imaging of cell and mitochondrial membrane potentials
15. Tetramethyl rhodamine methyl ester (TMRM) is suitable for cytofluorometric measurements of mitochondrial membrane potential in cells treated with digitonin
16. 6(3) or rhodamine 123, is a reliable fluorescent probe to assess δψ changes in intact cells: Implications for studies on mitochondrial functionality during apoptosis
17. Use of rhodamine 123 to investigate alterations in mitochondrial activity in isolated mouse liver mitochondria
18. Localization of endoplasmic reticulum in living and glutaraldehyde-fixed cells with fluorescent dyes
19. J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential
20. A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5′,6,6′-tetrachloroq-1,1′,3,3′tetraethylbenzimidazo lcarbocyanine iodide (JC-1)
21. Photomodification of mitochondrial proteins by azido fatty acids and its effect on mitochondrial energetics: Further evidence for the role of the ADP/ATP carrier in fatty-acid-mediated uncoupling
22. Membrane potential can be determined in individual cells from the Nernstian distribution of cationic dyes
23. Imaging in five dimensions: Time-dependent membrane potentials in individual mitochondria