메뉴 건너뛰기




Volumn 56, Issue 21, 1996, Pages 4956-4964

Growth inhibition of human prostate cells in vitro by novel inhibitors of androgen synthesis

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTANOLONE; FINASTERIDE; KETOCONAZOLE; PREGNANE DERIVATIVE; STEROID 17ALPHA MONOOXYGENASE; STEROID 5ALPHA REDUCTASE INHIBITOR; TESTOSTERONE; TETRAHYDROCORTISONE;

EID: 0029950308     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (37)

References (44)
  • 1
    • 0002557103 scopus 로고
    • Endocrinology of the prostate
    • H. Lepor and R. K. Lawson (eds.), Philadelphia W, B Saunders
    • Cheng, E., Lee, C , and Grayhack, J. Endocrinology of the prostate. In: H. Lepor and R. K. Lawson (eds.), Prostate Diseases, pp 57-73. Philadelphia W, B Saunders, 1993.
    • (1993) Prostate Diseases , pp. 57-73
    • Cheng, E.1    Lee, C.2    Grayhack, J.3
  • 2
    • 0019888152 scopus 로고
    • 21 steroid side chain cleavage: Spectral and binding studies
    • 21 steroid side chain cleavage: spectral and binding studies. J. Biol. Chem. 250: 6134-6139, 1981.
    • (1981) J. Biol. Chem. , vol.250 , pp. 6134-6139
    • Nakajin, S.1    Hall, P.F.2    Onoda, M.3
  • 4
    • 0014429464 scopus 로고
    • The conversion of testosterone to 5α-androstan-17β-ol-3-one by rat prostate in vivo and in vitro
    • Bruchovsky, N., and Wilson, J D The conversion of testosterone to 5α-androstan-17β-ol-3-one by rat prostate in vivo and in vitro J Biol. Chem , 243: 2012-2021, 1968
    • (1968) J Biol. Chem , vol.243 , pp. 2012-2021
    • Bruchovsky, N.1    Wilson, J.D.2
  • 5
    • 78651135446 scopus 로고
    • Some aspects of relation of structure of steroids to their prostate-stimulating effects
    • E. P. Vollmer (ed.), National Cancer Institute Monograph No 12, Washington, DC U. S. Government Printing Office
    • Saunders, F J Some aspects of relation of structure of steroids to their prostate-stimulating effects. In: E. P. Vollmer (ed.), Prostate and Related Tissues (National Cancer Institute Monograph No 12), pp. 139-159 Washington, DC U. S. Government Printing Office, 1963.
    • (1963) Prostate and Related Tissues , pp. 139-159
    • Saunders, F.J.1
  • 6
    • 85003182599 scopus 로고
    • Relative potency of various steroids in anabolic-androgenic assay using the castrated rat
    • Dorfman, R. I , and Kincl, F. A. Relative potency of various steroids in anabolic-androgenic assay using the castrated rat. Endocrinology, 72, 259-266, 1963.
    • (1963) Endocrinology , vol.72 , pp. 259-266
    • Dorfman, R.I.1    Kincl, F.A.2
  • 7
    • 0022852328 scopus 로고
    • The dihydrotestosterone (DHT) hypothesis of prostate cancer and its therapeutic implications
    • Petrow, V The dihydrotestosterone (DHT) hypothesis of prostate cancer and its therapeutic implications. Prostate, 9 343-361, 1986.
    • (1986) Prostate , vol.9 , pp. 343-361
    • Petrow, V.1
  • 9
    • 0026587321 scopus 로고
    • Nuclear localization of androgen receptor in heterogeneous samples of normal, hyperplastic and neoplastic human prostate
    • Chodak, G. W., Kranc, D. M., Puy, L. A., Takeda, H , Johnson, K., and Chang, C. Nuclear localization of androgen receptor in heterogeneous samples of normal, hyperplastic and neoplastic human prostate J. Urol., 147: 798-803, 1992.
    • (1992) J. Urol. , vol.147 , pp. 798-803
    • Chodak, G.W.1    Kranc, D.M.2    Puy, L.A.3    Takeda, H.4    Johnson, K.5    Chang, C.6
  • 10
    • 0001189211 scopus 로고
    • Studies on prostatic cancer. II. The effects of castration on advanced carcinoma of the prostate gland
    • Huggins, C., Stevens, R. E , and Hodges, C. V. Studies on prostatic cancer. II. The effects of castration on advanced carcinoma of the prostate gland. Arch. Surg , 43: 209-223, 1941.
    • (1941) Arch. Surg , vol.43 , pp. 209-223
    • Huggins, C.1    Stevens, R.E.2    Hodges, C.V.3
  • 13
    • 0000139770 scopus 로고
    • Treatment of newly diagnosed stage D2 prostate cancer with leuprolide and flutamide or leuprolide alone, phase III: Prognostic significance of minimal disease
    • Crawford, E. D., Eisenberger, M., and McLeod, D. Treatment of newly diagnosed stage D2 prostate cancer with leuprolide and flutamide or leuprolide alone, phase III: prognostic significance of minimal disease J Urol., 147: 417A, 1992.
    • (1992) J Urol. , vol.147
    • Crawford, E.D.1    Eisenberger, M.2    McLeod, D.3
  • 14
    • 0028309781 scopus 로고
    • Role of maximal androgen blockade in advanced prostate cancer
    • Denis, L. Role of maximal androgen blockade in advanced prostate cancer Prostate, 5 (Suppl ) 17-22, 1994.
    • (1994) Prostate , vol.5 , Issue.SUPPL. , pp. 17-22
    • Denis, L.1
  • 15
    • 0021167082 scopus 로고
    • Ketoconazole therapy for advanced prostatic cancer
    • Trachtenberg, J , and Pont, A. Ketoconazole therapy for advanced prostatic cancer Lancet, 2: 433-435, 1984
    • (1984) Lancet , vol.2 , pp. 433-435
    • Trachtenberg, J.1    Pont, A.2
  • 16
    • 0022625136 scopus 로고
    • Objective responses to ketoconazole therapy in patients with relapsed progressive prostatic cancer
    • Williams, G , Kerle, D J , Doble, A , Dunlop, H., Smith, C , Allen, J., Yeo, T , and Bloom, S. R Objective responses to ketoconazole therapy in patients with relapsed progressive prostatic cancer Br J Urol , 58: 45-51, 1986.
    • (1986) Br J Urol , vol.58 , pp. 45-51
    • Williams, G.1    Kerle, D.J.2    Doble, A.3    Dunlop, H.4    Smith, C.5    Allen, J.6    Yeo, T.7    Bloom, S.R.8
  • 17
    • 0024343385 scopus 로고
    • High dose ketoconazole for the treatment of hormone refractory metastatic prostate cancer: 16 cases and review of the literature
    • Jubelirer, S. J , and Hogan, T. High dose ketoconazole for the treatment of hormone refractory metastatic prostate cancer: 16 cases and review of the literature. J Urol , 142: 89-91, 1989
    • (1989) J Urol , vol.142 , pp. 89-91
    • Jubelirer, S.J.1    Hogan, T.2
  • 18
    • 0026449007 scopus 로고
    • Sequential androgen blockade, a biological study in the inhibition of prostatic growth
    • Fleshner, N. E , and Trachtenberg, J Sequential androgen blockade, a biological study in the inhibition of prostatic growth. J Urol , 148 1928-1931, 1992.
    • (1992) J Urol , vol.148 , pp. 1928-1931
    • Fleshner, N.E.1    Trachtenberg, J.2
  • 19
    • 0027372343 scopus 로고
    • Treatment of advanced prostate cancer with the combination of finasteride plus flutamide early results
    • Fleshner, N. E , and Trachtenberg, J. Treatment of advanced prostate cancer with the combination of finasteride plus flutamide early results. Eur Urol , 24 (Suppl. 2): 106-112, 1993.
    • (1993) Eur Urol , vol.24 , Issue.2 SUPPL. , pp. 106-112
    • Fleshner, N.E.1    Trachtenberg, J.2
  • 20
    • 0028925624 scopus 로고
    • Inhibition of androgen synthesis by 22-hydroximino-23,24-bisnor-4-cholen-3-one
    • Li, J-S., Li, Y , Son, C., and Brodie, A M. H Inhibition of androgen synthesis by 22-hydroximino-23,24-bisnor-4-cholen-3-one. Prostate, 26: 140-150, 1995.
    • (1995) Prostate , vol.26 , pp. 140-150
    • Li, J.-S.1    Li, Y.2    Son, C.3    Brodie, A.M.H.4
  • 21
    • 0028225858 scopus 로고
    • A ligand-dependent bipartite nuclear targeting signal in the human androgen receptor
    • Zhou, Z-X., Sar, M., Simental, J. A., Lane, M. V., and Wilson, E M. A ligand-dependent bipartite nuclear targeting signal in the human androgen receptor. J. Biol Chem. 269: 13115-13123, 1994
    • (1994) J. Biol Chem. , vol.269 , pp. 13115-13123
    • Zhou, Z.-X.1    Sar, M.2    Simental, J.A.3    Lane, M.V.4    Wilson, E.M.5
  • 23
    • 0018405978 scopus 로고
    • Anti-androgenicity of flutamide and its metabolite Sch 16423
    • Neri, R., Peets, E , and Watnick, A. Anti-androgenicity of flutamide and its metabolite Sch 16423 Biochem. Soc. Trans., 7, 565-569, 1979.
    • (1979) Biochem. Soc. Trans. , vol.7 , pp. 565-569
    • Neri, R.1    Peets, E.2    Watnick, A.3
  • 25
    • 0000941760 scopus 로고
    • Bilateral adrenalectomy in prostatic cancer
    • Huggins, C , and Scott, W. W. Bilateral adrenalectomy in prostatic cancer. Ann. Surg , 122: 1031-1041, 1945.
    • (1945) Ann. Surg , vol.122 , pp. 1031-1041
    • Huggins, C.1    Scott, W.W.2
  • 26
    • 0015970931 scopus 로고
    • Steroids of adrenal origin metabolized by human prostatic tissue both in vivo and in vitro
    • Harper, M E , Pike, A., Peeling, W B , and Griffiths, K. Steroids of adrenal origin metabolized by human prostatic tissue both in vivo and in vitro. J Endocrinol., 60: 117-125, 1974.
    • (1974) J Endocrinol. , vol.60 , pp. 117-125
    • Harper, M.E.1    Pike, A.2    Peeling, W.B.3    Griffiths, K.4
  • 28
    • 0025648521 scopus 로고
    • Stimulatory effects of antiandrogens on LNCaP human prostate tumor cell growth, EGF-receptor level and acid phosphatase secretion
    • Schuurmans, A. L. G., Bolt, J., Veldscholte, J., and Mulder, E. Stimulatory effects of antiandrogens on LNCaP human prostate tumor cell growth, EGF-receptor level and acid phosphatase secretion. J Steroid Biochem Mol Biol , 37: 849-853, 1990.
    • (1990) J Steroid Biochem Mol Biol , vol.37 , pp. 849-853
    • Schuurmans, A.L.G.1    Bolt, J.2    Veldscholte, J.3    Mulder, E.4
  • 29
    • 0024351830 scopus 로고
    • Aberrant response in vitro of hormone responsive prostate cancer cells to antiandrogens
    • Wilding, G., Chen, M., and Gelmann, E. P. Aberrant response in vitro of hormone responsive prostate cancer cells to antiandrogens. Prostate, 14: 103-115, 1989.
    • (1989) Prostate , vol.14 , pp. 103-115
    • Wilding, G.1    Chen, M.2    Gelmann, E.P.3
  • 30
    • 0026591729 scopus 로고
    • Anti-androgens and mutated androgen receptor of LNCaP cells: Differential effects on binding affinity, heat-shock protein interaction, and transcription activation
    • Veldscholte, J., Berrevoets, C. A., Brinkmann, A. O., Grootegoed, J. A., and Mulder, E. Anti-androgens and mutated androgen receptor of LNCaP cells: differential effects on binding affinity, heat-shock protein interaction, and transcription activation. Biochemistry, 31, 2393-2399, 1992.
    • (1992) Biochemistry , vol.31 , pp. 2393-2399
    • Veldscholte, J.1    Berrevoets, C.A.2    Brinkmann, A.O.3    Grootegoed, J.A.4    Mulder, E.5
  • 31
    • 0025940350 scopus 로고
    • Stimulation of apolipoprotein D secretion by steroids coincides with inhibition of cell proliferation in human LNCaP prostate cancer cells
    • Simard, J., Veilleux, R., de Launoit, Y , Haagensen, D. E , and Labrie, F. Stimulation of apolipoprotein D secretion by steroids coincides with inhibition of cell proliferation in human LNCaP prostate cancer cells. Cancer Res., 51: 4336-4341, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 4336-4341
    • Simard, J.1    Veilleux, R.2    De Launoit, Y.3    Haagensen, D.E.4    Labrie, F.5
  • 32
    • 0024241675 scopus 로고
    • Regulation of growth and epidermal growth factor receptor levels of LNCaP prostate tumor cells by different steroids
    • Schuurmans, A. L. G., Bolt, J , Voorhorst, M M., Blankenstein, R. A., and Mulder, E. Regulation of growth and epidermal growth factor receptor levels of LNCaP prostate tumor cells by different steroids. Int. J Cancer, 42: 917-922, 1988.
    • (1988) Int. J Cancer , vol.42 , pp. 917-922
    • Schuurmans, A.L.G.1    Bolt, J.2    Voorhorst, M.M.3    Blankenstein, R.A.4    Mulder, E.5
  • 33
    • 0023010543 scopus 로고
    • Androgen-dependent growth regulation of and release of specific protein(s) by the androgen receptor containing human prostate tumor cell line LNCaP
    • Berns, E. M. J J., de Boer, W., and Mulder, E. Androgen-dependent growth regulation of and release of specific protein(s) by the androgen receptor containing human prostate tumor cell line LNCaP. Prostate, 9: 247-259, 1986.
    • (1986) Prostate , vol.9 , pp. 247-259
    • Berns, E.M.J.J.1    De Boer, W.2    Mulder, E.3
  • 34
    • 0026755277 scopus 로고
    • Immunohistochemistry and biochemistry in detection of androgen, progesterone and estrogen receptors in benign and malignant human prostatic tumors
    • Brolin, J., Skoog, L., and Ekman, P Immunohistochemistry and biochemistry in detection of androgen, progesterone and estrogen receptors in benign and malignant human prostatic tumors. Prostate, 20: 281-295, 1992
    • (1992) Prostate , vol.20 , pp. 281-295
    • Brolin, J.1    Skoog, L.2    Ekman, P.3
  • 36
    • 0022390704 scopus 로고
    • Species differences in prostatic steroid 5α-reductases of rat, dog, and human
    • Liang, T., Cascieri, M. A., Cheung, A. H., Reynolds, G. F , and Rasmusson, G. H. Species differences in prostatic steroid 5α-reductases of rat, dog, and human. Endocrinology, 117: 571-579, 1985.
    • (1985) Endocrinology , vol.117 , pp. 571-579
    • Liang, T.1    Cascieri, M.A.2    Cheung, A.H.3    Reynolds, G.F.4    Rasmusson, G.H.5
  • 41
    • 0027203411 scopus 로고
    • Flutamide withdrawal syndrome: Its impact on clinical trials in hormone-refractory prostate cancer
    • Scher, H. I., and Kelly, W. K. Flutamide withdrawal syndrome: its impact on clinical trials in hormone-refractory prostate cancer. J. Clin. Oncol., 11: 1566-1572, 1993.
    • (1993) J. Clin. Oncol. , vol.11 , pp. 1566-1572
    • Scher, H.I.1    Kelly, W.K.2
  • 42
    • 0027249588 scopus 로고
    • Response to flutamide withdrawal in advanced prostate cancer in progression under combination therapy
    • Dupont, A., Gomez, J-L., Cusan, L., Koutsilieris, M., and Librie, F. Response to flutamide withdrawal in advanced prostate cancer in progression under combination therapy. J. Urol., 150 908-913, 1993.
    • (1993) J. Urol. , vol.150 , pp. 908-913
    • Dupont, A.1    Gomez, J.-L.2    Cusan, L.3    Koutsilieris, M.4    Librie, F.5
  • 43
    • 85003173512 scopus 로고
    • Mutant androgen receptor detected in an advanced-stage prostatic carcinoma is activated by adrenal androgens and progesterone
    • Culig, Z., Hobisch, A., Cronauer, M. V., Cato, A. C. B , Hittmair, A., Radmayr, C., Eberle, J., Bartsch, G , and Klocker, H. Mutant androgen receptor detected in an advanced-stage prostatic carcinoma is activated by adrenal androgens and progesterone. Mol. Endocrinol., 7: 1541-1550, 1993.
    • (1993) Mol. Endocrinol. , vol.7 , pp. 1541-1550
    • Culig, Z.1    Hobisch, A.2    Cronauer, M.V.3    Cato, A.C.B.4    Hittmair, A.5    Radmayr, C.6    Eberle, J.7    Bartsch, G.8    Klocker, H.9
  • 44
    • 0028804247 scopus 로고
    • Mutant androgen receptors in prostatic tumors distinguish between amino-acid sequence requirements for transactivation and ligand binding
    • Peterziel, H., Culig, Z , Stober, J., Hobisch, A., Radmayr, C., Bartsch, G., Klocker, H., and Cato, A. C B. Mutant androgen receptors in prostatic tumors distinguish between amino-acid sequence requirements for transactivation and ligand binding. Int. J. Cancer, 63: 544-550, 1995.
    • (1995) Int. J. Cancer , vol.63 , pp. 544-550
    • Peterziel, H.1    Culig, Z.2    Stober, J.3    Hobisch, A.4    Radmayr, C.5    Bartsch, G.6    Klocker, H.7    Cato, A.C.B.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.