Localization and signaling of Gβ subunit Ste4p are controlled by a-factor receptor and the a-specific protein Asg7p

Molecular and Cellular Biology

Volumn 20, Issue 23, 2000, Pages 8826-8835

  Kim, J ^a   Bortz, E ^a   Zhong, H ^a   Leeuw, T ^a   Leberer, E ^a   Vershon, A K ^a   Hirsch, J P ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; GUANINE NUCLEOTIDE BINDING PROTEIN; MATING HORMONE ALPHA FACTOR; PHEROMONE; PROTEIN ASG7P; PROTEIN STE4P; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BETA CHAIN; CELL LINE; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HAPLOIDY; MATING; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; YEAST CELL;

CELL COMPARTMENTATION; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GTP-BINDING PROTEIN BETA SUBUNITS; HETEROTRIMERIC GTP-BINDING PROTEINS; MODELS, BIOLOGICAL; PHEROMONES; PROTEIN BINDING; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, MATING FACTOR; RECEPTORS, PHEROMONE; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0034462601     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.23.8826-8835.2000     Document Type: Article

References (38)

1. KSR-1 binds to G-protein βγ subunits and inhibits βγ-induced mitogen-activated protein kinase activation
2. Pheromone-induced phosphorylation of a G protein β subunit in S. cerevisiae is associated with an adaptive response to mating pheromone
3. 1 arrest response in cells expressing an inappropriate pheromone receptor
4. The DAF2-2 mutation, a dominant inhibitor of the STE4 step in the α-factor signalling pathway of Saccharomyces cerevisiae MATa cells
5. 'Marker swap' plasmids: Convenient tools for budding yeast molecular genetics
6. A potential positive feedback loop controlling CLN1 and CLN2 gene expression at the start of the yeast cell cycle
7. The yeast SCG1 gene: A Gα-like protein implicated in the a- and α-factor response pathway
8. Meiotic gene conversion and crossing over: Their relationship to each other and to chromosome synapsis and segregation
9. Crystal structure at 2.4 Å resolution of the complex of transducin βγ and its regulator, phosducin
10. New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites
11. Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer
12. Subunit interactions of GTP-binding proteins
13. The pheromone receptors inhibit the pheromone response pathway in Saccharomyces cerevisiae by a process that is independent of their associated Gα protein
14. The Gβγ complex of the yeast pheromone response pathway: Subcellular fractionation and protein-protein interactions
15. Transformation of intact yeast cells with alkali cations
16. S. cerevisiae α pheromone receptors activate a novel signal transduction pathway for mating partner discrimination
17. β subunit
18. Dominant-negative mutants of a yeast G-protein β subunit identify two functional regions involved in pheromone signalling
19. Pheromone signalling and polarized morphogenesis in yeast
20. Functional characterization of the Cdc42p binding domain of yeast Ste20p protein kinase
21. The photoreceptor-specific 33 kDa phosphoprotein of mammalian retina: Generation of monospecific antibodies and localization by immunocytochemistry
22. β protein of Saccharomyces cerevisiae does not affect its mating-specific signaling function
23. Nuclear shuttling of yeast scaffold Ste5 is required for its recruitment to the plasma membrane and activation of the mating MAPK cascade
24. Significance of C-terminal cysteine modifications to the biological activity of the Saccharomyces cerevisiae a-factor mating pheromone
25. Identification and regulation of a gene required for cell fusion during mating of the yeast Saccharomyces cerevisiae
26. Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast
27. Rhodopsin/transducin interactions. I. Characterization of the binding of the transducin-βγ subunit complex to rhodopsin using fluorescence spectroscopy
28. Role of βγ subunits of G proteins in targeting the β-adrenergic receptor kinase to membrane-bound receptors
29. Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gβγ complex underlies activation of the yeast pheromone response pathway
30. Asg7p-Ste3p repression of pheromone signaling: Regulation of the zygotic transition to vegetative growth
31. Pheromone response and signal transduction during the mating process of Saccharomyces cerevisiae
32. Receptor and membrane interaction sites on Gβ
33. PCR-synthesis of marker cassettes with long flanking homology regions for gene disruptions in S. cerevisiae
34. Plugging it in: Signaling circuits and the yeast cell cycle
35. The phosphorylation state of phosducin determines its ability to block transducin subunit interactions and inhibit transducin binding to activated rhodopsin
36. Identification of target sites of the α2-Mcm1 repressor complex in the yeast genome