Type 4 cyclic adenosine monophosphate-specific phosphodiesterases are expressed in discrete subcellular compartments during rat spermiogenesis

Endocrinology

Volumn 140, Issue 5, 1999, Pages 2297-2306

  Salanova, Michele ^a   Chun, Sang Young ^b,c   Iona, Saveria ^b   Puri, Claudia ^b   Stefanini, Mario ^b   Conti, Marco ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c Chonnam National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP PHOSPHODIESTERASE; ISOENZYME; MESSENGER RNA; RIBONUCLEASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; MALE; NONHUMAN; PACHYTENE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SPERMATID; SPERMATOCYTE; SPERMATOGENESIS; SPERMATOZOON MATURATION;

EID: 0033306841     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.140.5.6686     Document Type: Article

References (51)

1. The cyclic AMP-mediated stimulation of cell proliferation
2. A cAMP-phosphodiesterase consols PKA-dependent differentiation
3. Structure and regulation of G protein-coupled receptors: The beta 2-adrenergic receptor as a model
4. Signal transduction and gene regulation: The nuclear response to cAMP
5. Localization of A-kinase through anchoring proteins
6. A kinase anchor proteins and the intracellular targeting of signals carried by cyclic AMP
7. Cyclic nucleotide phosphodiesterases: Functional implications of multiple isoforms
8. cAMP compartmentation is responsible for a local activation of cardiac Ca2+ channels by beta-adrenergic agonists
9. Tailoring cAMP-signalling responses through isoform multiplicity
10. Recent progress in understanding the hormonal regulation of phosphodiesterases
11. The multiple PDE4 cyclic adenosine monophosphate-specifc phosphodiesterase gene family: Intracellular targeting, regulation and selective inhibition by compounds exerting anti-inflammatory and antidepressant action
12. The ratPDE3/IVd phosphodiesterase gene codes for multiple proteins differentially activated by cAMP-dependent protein kinase
13. Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation
14. Stimulation of p70S6 kinase via a growth hormone-controlled phosphatidylinositol 3-kinase pathway leads to the activation of a PDE4A cyclic AMP-specific phosphodiesterase in 3T3-F442A preadipocytes
15. The cAMP phosphodiesterase RD1 (rPDE-IVA) is expressed in brain as a 68kDa protein having a unique inhibitory domain at its N-terminus which confers membrane targeting
16. Engineered deletion of the unique N-terminal domain of the cyclic AMP-specific phosphodiesterase RD1 prevents plasma membrane association and the attainment of enhanced thermostability without altering its sensitivity to inhibition by rolipram
17. Chimeric constructs show that the unique N-terminal domain of the cyclic AMP phosphodiesterase RD1 (RNPDE4A1A; rPDE-IVA1) can confer membrane association upon the normally cytosolic protein chloramphenicol acetyltransferase
18. The SH3 domain of Src tyrosyl protein kinase interacts with the N-terminal splice region of the PDE4A cAMP-specific phosphodiesterase RPDE-6 (RNPDE4A5)
19. The human cyclic AMP-specific phosphodiesterase PDE-46 (HSPDE4A4B) expressed in transfected COS7 cells occurs as both particulate and cytosolic species that exhibit distinct kinetics of inhibition by the antidepressant nolipram
20. Developmental regulation of unique adenosine 3',5'-monophosphate-specific phosphodiesterase variants during rat spermatogenesis
21. Follicle-stimulating hormone stimulates estradiol-17β synthesis in cultured Sertoli cells
22. Pure Sertoli cell cultures: A new model for the study of somatic-germ cell interactions
23. The separation, physical characterization, and differentiation kinetics of spermatogonial cells of the mouse
24. Localization of adenosine receptors in rat testicular cells
25. Stage and cell-specific expression of the adenosine 3',5' monophosphate-phosphodiesterase genes in the rat seminiferous epithelium
26. The mRNA encoding a high-affinity cAMP phosphodiesterase is regulated by hormones and cAMP
27. Characterization of the rolipram-sensitive, cyclic AMP-specific phosphodiesterases: Identification and differential expression of immunologically distinct forms in the rat brain
28. Subcellular localization of Forssman glycolipid in epithelial MDCK cells by immuno-electronmicroscopy after freeze-substitution
29. Freeze-substitution and Lowicryl HM20 embedding of fixed rat brain: Suitability for immunogold ultrastructural localization of neural antigens
30. Use of colloidal gold particles in double-labeling immunoelectron microscopy of ultrathin frozen tissue sections
31. Properties and hormonal regulation of two structurally related cAMP phosphodiesterases from the rat Sertoli cell
32. Characterization of a hormone-inducible, high affinity adenosine 3'-5'-cyclic monophosphate phosphodiesterase from the rat Sertoli cell
33. Characterization of five different proteins produced by alternatively spliced mRNAs from the human cAMP-specific phosphodiesterase PDE4D gene
34. Characterization of an intronic promoter of a cyclic adenosine 3',5'-monophosphate (cAMP)-specific phosphodiesterase gene that confers hormone and cAMP inducibility
35. The short-term activation of a rolipram-sensitive, cAMP-specific phosphodiesterase by thyroid-stimulating hormone in thyroid FRTL-5 cells is mediated by a cAMP-dependent phosphorylation
36. Subcellular localization of the PDE variants
37. Unique adenosine 3',5' cyclic monophosphate phosphodiesterase messenger ribonucleic acids in rat spermatogenic cells: Evidence for differential gene expression during spermatogenesis
38. Heterologous expression and purification of recombinant rolipram-sensitive cyclic AMP-specific phosphodiesterases
39. Insertional mutation that causes acrosomal hypo-development: Its relationship to sperm head shaping
40. Linkage of manchette microtubules to the nuclear envelope and observations of the role of the manchette in nuclear shaping during spermiogenesis in rodents
41. Characterization of the structure of a low Km, rolipram-sensitive cAMP phosphodiesterase. Mapping of the catalytic domain
42. Recombinant expression of a type IV, cAMP-specific phosphodiesterase: Characterization and structure-function studies of deletion mutants
43. Gene expression during spermatogenesis
44. Translational regulation and deadenylation of a protamine mRNA during spermiogenesis in the mouse
45. Spermiogenesis deficiency and germ-cell apoptosis in CREM-mutant mice
46. Severe impairment of spermatogenesis in mice lacking the CREM gene
47. Characterization of S-AKAP84, a novel developmentally regulated A kinase anchor protein of male germ cells
48. Assembly of AKAP82, a protein kinase A anchor protein, into the fibrous sheath of mouse sperm
49. Organelle-specific targeting of protein kinase AII (PKAII). Molecular and in situ characterization of murine A kinase anchor proteins that recruit regulatory subunits of PKAII to the cytoplasmic surface of mitochondria
50. Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motility
51. Enhancement of motility and acrosome reaction in human spermatozoa: Differential activation by type-specific phosphodiesterase inhibitors