메뉴 건너뛰기




Volumn 83, Issue 12, 1998, Pages 4386-4390

Activating mutations of the G(s)α gene are associated with low levels of Gsα protein in growth hormone-secreting tumors

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; GROWTH HORMONE; GUANINE NUCLEOTIDE BINDING PROTEIN; MUTANT PROTEIN; CHOLERA TOXIN; HUMAN GROWTH HORMONE; MESSENGER RNA;

EID: 0032252404     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.83.12.5354     Document Type: Article
Times cited : (50)

References (29)
  • 1
    • 0031158860 scopus 로고    scopus 로고
    • Genetic basis of endocrine disease: Pituitary tumor pathogenesis
    • 1. Shimon I, Melmed S. 1997 Genetic basis of endocrine disease: pituitary tumor pathogenesis. J Clin Endocrinol Metab. 82:1675-1681.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1675-1681
    • Shimon, I.1    Melmed, S.2
  • 4
    • 15144342434 scopus 로고    scopus 로고
    • Mutations of the MEN 1 tumor suppressor gene in pituitary tumors
    • 4. Zhuang Z, Ezzat SZ, Vortmejer AO, et al. 1997 Mutations of the MEN 1 tumor suppressor gene in pituitary tumors. Cancer Res. 57:5446-5451.
    • (1997) Cancer Res , vol.57 , pp. 5446-5451
    • Zhuang, Z.1    Ezzat, S.Z.2    Vortmejer, A.O.3
  • 5
    • 0031732536 scopus 로고    scopus 로고
    • Molecular characterization of the Men 1 tumor suppressor gene in sporadic pituitary tumors
    • 5. Prezant TR, Levine J, Melmed S. 1998 Molecular characterization of the Men 1 tumor suppressor gene in sporadic pituitary tumors. J Clin Endocrinol Metab. 83:1388-1391.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1388-1391
    • Prezant, T.R.1    Levine, J.2    Melmed, S.3
  • 6
    • 1842413392 scopus 로고
    • Growth hormone releasing factor stimulates cell proliferation of somatotrophs in vitro
    • 6. Billestrup N, Swanson LW, Vale W. 1986 Growth hormone releasing factor stimulates cell proliferation of somatotrophs in vitro. Proc Natl Acad Sci USA. 83:6854-6857.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 6854-6857
    • Billestrup, N.1    Swanson, L.W.2    Vale, W.3
  • 7
    • 0025127424 scopus 로고
    • Two G protein oncogenes in human endocrine tumors
    • 7. Lyons J, Landis CA, Harsh G, et al. 1990 Two G protein oncogenes in human endocrine tumors. Science. 249:655-659.
    • (1990) Science , vol.249 , pp. 655-659
    • Lyons, J.1    Landis, C.A.2    Harsh, G.3
  • 11
    • 0025965495 scopus 로고
    • Activation of the cyclic AMP cascade as an oncogenic mechanism: The thyroid example
    • 11. Maenhaut C, Roger PP, Reuse S, Dumont JE. 1991 Activation of the cyclic AMP cascade as an oncogenic mechanism: the thyroid example. Biochimie. 73:29-36.
    • (1991) Biochimie , vol.73 , pp. 29-36
    • Maenhaut, C.1    Roger, P.P.2    Reuse, S.3    Dumont, J.E.4
  • 13
    • 0029961869 scopus 로고    scopus 로고
    • Oncogenic role of heterotrimeric G proteins
    • 13. Vallar L. 1996 Oncogenic role of heterotrimeric G proteins. Cancer Surv. 27:325-338.
    • (1996) Cancer Surv , vol.27 , pp. 325-338
    • Vallar, L.1
  • 14
    • 0030612245 scopus 로고    scopus 로고
    • sα enhances activation of the adenylyl cyclase signal transduction cascade
    • sα enhances activation of the adenylyl cyclase signal transduction cascade. Mol Endocrinol. 11:1053-1061.
    • (1997) Mol Endocrinol , vol.11 , pp. 1053-1061
    • Yang, X.1    Lee, F.Y.G.2    Wand, G.S.3
  • 15
    • 0026335108 scopus 로고
    • Increased stimulatory G protein in neoplastic human thyroid tissues
    • 15. Siperstein AE, Miller RA, Landis C, Bourne H, Clark OH. 1991 Increased stimulatory G protein in neoplastic human thyroid tissues. Surgery. 110:949-953.
    • (1991) Surgery , vol.110 , pp. 949-953
    • Siperstein, A.E.1    Miller, R.A.2    Landis, C.3    Bourne, H.4    Clark, O.H.5
  • 17
    • 0029664322 scopus 로고    scopus 로고
    • sα protein-adenylate cyclase pathway may not be sufficient to generate toxic thyroid adenomas
    • sα protein-adenylate cyclase pathway may not be sufficient to generate toxic thyroid adenomas. J Clin Endocrinol Metab. 81:1898-1904.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 1898-1904
    • Derwahl, M.1    Hamacher, C.2    Russo, D.3
  • 18
    • 0029017174 scopus 로고
    • The cyclic adenosine 3′,5′ monophosphate-responsive factor CREB is constitutively activated in human somatotroph adenomas
    • 18. Bertherat J, Chanson P, Montminy M. 1995 The cyclic adenosine 3′,5′ monophosphate-responsive factor CREB is constitutively activated in human somatotroph adenomas. Mol Endocrinol. 9:777-783.
    • (1995) Mol Endocrinol , vol.9 , pp. 777-783
    • Bertherat, J.1    Chanson, P.2    Montminy, M.3
  • 19
    • 0000863638 scopus 로고
    • Morphological studies on mixed growth hormone (GH) and prolactin (PRL)-secreting adenomas. Coexistence of GH and PRL in the same secretory granules
    • 19. Bassetti M, Spada A, Arosio M, Vallar L, Brina M, Giannattasio G. 1986 Morphological studies on mixed growth hormone (GH) and prolactin (PRL)-secreting adenomas. Coexistence of GH and PRL in the same secretory granules. J Clin Endocrinol Metab. 418:405-410.
    • (1986) J Clin Endocrinol Metab , vol.418 , pp. 405-410
    • Bassetti, M.1    Spada, A.2    Arosio, M.3    Vallar, L.4    Brina, M.5    Giannattasio, G.6
  • 21
    • 0031023099 scopus 로고    scopus 로고
    • Intercellular adehesion molecule-1 is expressed on human granulosa cells and mediates their binding to lymphoid cells
    • 21. Viganò P, Gaffuri B, Ragni G, Di Blasio AM, Vignali M. 1997 Intercellular adehesion molecule-1 is expressed on human granulosa cells and mediates their binding to lymphoid cells. J Clin Endocrinol Metab 82:101-105.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 101-105
    • Viganò, P.1    Gaffuri, B.2    Ragni, G.3    Di Blasio, A.M.4    Vignali, M.5
  • 22
    • 0030656476 scopus 로고    scopus 로고
    • Immunodetection of G proteins in human pituitary adenomas; evidence for a low expression of proteins of the Gi subfamily
    • 22. Ballarè E, Mantovani S, Bassetti M, Lania A, Spada A. 1997 Immunodetection of G proteins in human pituitary adenomas; evidence for a low expression of proteins of the Gi subfamily. Eur J Endocrinol. 137:482-489.
    • (1997) Eur J Endocrinol , vol.137 , pp. 482-489
    • Ballarè, E.1    Mantovani, S.2    Bassetti, M.3    Lania, A.4    Spada, A.5
  • 24
    • 0023522307 scopus 로고
    • s and adenylate cyclase activity in human GH-secreting pituitary adenomas
    • s and adenylate cyclase activity in human GH-secreting pituitary adenomas. Nature. 330:566-567.
    • (1987) Nature , vol.330 , pp. 566-567
    • Vallar, L.1    Spada, A.2    Giannattasio, G.3
  • 25
    • 0027202237 scopus 로고
    • Clinical and biochemical characteristics of acromegalic patients harboring gsp-positive and gsp-negative pituitary rumors
    • 25. Adams EF, Brockmeier S, Friedmann E, Roth M, Buchfelder M, Fahlbusch R. 1993 Clinical and biochemical characteristics of acromegalic patients harboring gsp-positive and gsp-negative pituitary rumors. Neurosurgery. 33:198-203.
    • (1993) Neurosurgery , vol.33 , pp. 198-203
    • Adams, E.F.1    Brockmeier, S.2    Friedmann, E.3    Roth, M.4    Buchfelder, M.5    Fahlbusch, R.6
  • 28
    • 0026474549 scopus 로고
    • s in intact cells alters its abundance, rate of degradation and membrane avidity
    • s in intact cells alters its abundance, rate of degradation and membrane avidity. J Cell Biol. 119:1297-1305.
    • (1992) J Cell Biol , vol.119 , pp. 1297-1305
    • Levis, M.J.1    Bourne, H.R.2
  • 29
    • 0029941917 scopus 로고    scopus 로고
    • Mutations in G proteins and G protein-coupled receptors in endocrine disease
    • 29. Spiegel AM. 1996 Mutations in G proteins and G protein-coupled receptors in endocrine disease. J Clin Endocrinol Metab. 81:2434-2442.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 2434-2442
    • Spiegel, A.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.